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The map label for this gene is ygjG [C]

Identifier: 225686686

GI number: 225686686

Start: 890534

End: 891439

Strand: Direct

Name: ygjG [C]

Synonym: BMEA_B0909

Alternate gene names: 225686686

Gene position: 890534-891439 (Clockwise)

Preceding gene: 225686683

Following gene: 225686690

Centisome position: 75.12

GC content: 59.71

Gene sequence:

>906_bases
ATGGTTCTGGGCCGCGAGAAGGGGTATCACGGCGTCGGCTTTGGCGGCATTTCCGTCGGCGGCCTCGTCAACAACCGCTG
TGTCTTCCCGCAGATCCCCGCCGATCACCTGCGTCATACGCTCGATATCGAAAAGAACGCCTTCTCCAAGGGCCTGCCTG
CAAACGGCATCGAACTGGCCGACGATCTGGAACGCCTCGTACAATTGCATGGCGCTGAAAAGATCGCCGCCGTCATCGTT
GAACCCATGTCCGGTTCGGCTGGCGTCATCCTGCCGCCAAAGGGCTATCTGGAGCGCATCCGCGCCACGGCAGACAAATA
CGGCATCCTGCTCATTTTCGATGAAGTCATCACCGGCTTCGGCCGTCTCGGTACGCCGTTCGCGGTTGATTATTTCGGCG
TTGTCCCTGATCTCGTGACGACCGCCAAGGGCCTCACCAACGGCGCAATTCCGATGGGCGCCGTCTTTGCCGCCCGCAAG
GTCTATGACGGTCTGATGACCGGCCCGGAAAATGCCATCGAACTCTTCCATGGCTACACTTATTCCGGCCATCCGGTTGC
TTCCGCCGCCGGTTTGGCAACGCTTGAAATCTACGCCGAGGAAGGGCTTTTGACCCGCGGTGCAGGCCTTGCCGATTACT
GGCAGGAAGCGCTTCATTCGCTGAAAGGCGCGCCGAATGTCATCGATATCCGCAATCTTGGCCTTGTCGGCGCTGTCGAA
CTCGCATCGCGCAAGGATGCGCCGGGCGCCCGCGCCTACGACATTTTCGTCGAGTGTTTCAAGAAGGGCCTGCTTATCCG
CGTCACCGGCGACGTGATTGCACTGTCACCGCCGCTCATCATCGAAAAGGAACAGATCGACACGATCATTTCGGTTCTCG
GTGACGCCATCAAACGCGCGGCCTGA

Upstream 100 bases:

>100_bases
GACCGCGTGTTTTTCACCAATTCCGGTTCCGAGTCAGTCGATACGGCGCTGAAGATCAGCCATTGCCTATCAGCGCGCCA
TCGGCCAGGGCACCCGCACC

Downstream 100 bases:

>100_bases
TCATCACCCGGATCAAGCCGCAACCTGGCCGCCGCTGTTCCCCTGCGGCGGCTTTTTTCTTTCGGTTTTATCAGCCGTGA
GATGGCGTAAACCGCGCCAC

Product: Omega-amino acid--pyruvate aminotransferase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MVLGREKGYHGVGFGGISVGGLVNNRCVFPQIPADHLRHTLDIEKNAFSKGLPANGIELADDLERLVQLHGAEKIAAVIV
EPMSGSAGVILPPKGYLERIRATADKYGILLIFDEVITGFGRLGTPFAVDYFGVVPDLVTTAKGLTNGAIPMGAVFAARK
VYDGLMTGPENAIELFHGYTYSGHPVASAAGLATLEIYAEEGLLTRGAGLADYWQEALHSLKGAPNVIDIRNLGLVGAVE
LASRKDAPGARAYDIFVECFKKGLLIRVTGDVIALSPPLIIEKEQIDTIISVLGDAIKRAA

Sequences:

>Translated_301_residues
MVLGREKGYHGVGFGGISVGGLVNNRCVFPQIPADHLRHTLDIEKNAFSKGLPANGIELADDLERLVQLHGAEKIAAVIV
EPMSGSAGVILPPKGYLERIRATADKYGILLIFDEVITGFGRLGTPFAVDYFGVVPDLVTTAKGLTNGAIPMGAVFAARK
VYDGLMTGPENAIELFHGYTYSGHPVASAAGLATLEIYAEEGLLTRGAGLADYWQEALHSLKGAPNVIDIRNLGLVGAVE
LASRKDAPGARAYDIFVECFKKGLLIRVTGDVIALSPPLIIEKEQIDTIISVLGDAIKRAA
>Mature_301_residues
MVLGREKGYHGVGFGGISVGGLVNNRCVFPQIPADHLRHTLDIEKNAFSKGLPANGIELADDLERLVQLHGAEKIAAVIV
EPMSGSAGVILPPKGYLERIRATADKYGILLIFDEVITGFGRLGTPFAVDYFGVVPDLVTTAKGLTNGAIPMGAVFAARK
VYDGLMTGPENAIELFHGYTYSGHPVASAAGLATLEIYAEEGLLTRGAGLADYWQEALHSLKGAPNVIDIRNLGLVGAVE
LASRKDAPGARAYDIFVECFKKGLLIRVTGDVIALSPPLIIEKEQIDTIISVLGDAIKRAA

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI284507298, Length=256, Percent_Identity=31.25, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI4557809, Length=256, Percent_Identity=31.25, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI226442709, Length=281, Percent_Identity=29.1814946619217, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI37574042, Length=281, Percent_Identity=29.1814946619217, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI226442705, Length=281, Percent_Identity=29.1814946619217, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI13994255, Length=237, Percent_Identity=31.6455696202532, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI24119277, Length=270, Percent_Identity=28.5185185185185, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI145693181, Length=230, Percent_Identity=33.4782608695652, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789016, Length=259, Percent_Identity=32.4324324324324, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786991, Length=302, Percent_Identity=31.7880794701987, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1788044, Length=289, Percent_Identity=30.7958477508651, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787560, Length=254, Percent_Identity=33.0708661417323, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789759, Length=232, Percent_Identity=30.1724137931034, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1786349, Length=175, Percent_Identity=37.7142857142857, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32564660, Length=249, Percent_Identity=34.9397590361446, Blast_Score=124, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI25144274, Length=257, Percent_Identity=33.852140077821, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=257, Percent_Identity=33.852140077821, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71992977, Length=273, Percent_Identity=26.3736263736264, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323470, Length=307, Percent_Identity=28.9902280130293, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6324386, Length=326, Percent_Identity=28.5276073619632, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6324432, Length=304, Percent_Identity=27.3026315789474, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357415, Length=239, Percent_Identity=32.2175732217573, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI161085790, Length=237, Percent_Identity=35.4430379746835, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI28574759, Length=236, Percent_Identity=35.5932203389831, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI21356575, Length=238, Percent_Identity=34.0336134453782, Blast_Score=102, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 31901; Mature: 31901

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLGREKGYHGVGFGGISVGGLVNNRCVFPQIPADHLRHTLDIEKNAFSKGLPANGIELA
CCCCCCCCCCCCCCCCEEECCEECCCEECCCCCHHHHHHHHCCCHHHHHCCCCCCCCHHH
DDLERLVQLHGAEKIAAVIVEPMSGSAGVILPPKGYLERIRATADKYGILLIFDEVITGF
HHHHHHHHHHCHHHEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHCCEEEEEHHHHHHH
GRLGTPFAVDYFGVVPDLVTTAKGLTNGAIPMGAVFAARKVYDGLMTGPENAIELFHGYT
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
YSGHPVASAAGLATLEIYAEEGLLTRGAGLADYWQEALHSLKGAPNVIDIRNLGLVGAVE
CCCCCCHHHCCCEEEEEEECCCCEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHH
LASRKDAPGARAYDIFVECFKKGLLIRVTGDVIALSPPLIIEKEQIDTIISVLGDAIKRA
HHCCCCCCCCHHHHHHHHHHHCCEEEEEECCEEEECCCCEEEHHHHHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure
MVLGREKGYHGVGFGGISVGGLVNNRCVFPQIPADHLRHTLDIEKNAFSKGLPANGIELA
CCCCCCCCCCCCCCCCEEECCEECCCEECCCCCHHHHHHHHCCCHHHHHCCCCCCCCHHH
DDLERLVQLHGAEKIAAVIVEPMSGSAGVILPPKGYLERIRATADKYGILLIFDEVITGF
HHHHHHHHHHCHHHEEEEEEECCCCCCCEEECCHHHHHHHHHHHHHCCEEEEEHHHHHHH
GRLGTPFAVDYFGVVPDLVTTAKGLTNGAIPMGAVFAARKVYDGLMTGPENAIELFHGYT
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
YSGHPVASAAGLATLEIYAEEGLLTRGAGLADYWQEALHSLKGAPNVIDIRNLGLVGAVE
CCCCCCHHHCCCEEEEEEECCCCEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCHHHHH
LASRKDAPGARAYDIFVECFKKGLLIRVTGDVIALSPPLIIEKEQIDTIISVLGDAIKRA
HHCCCCCCCCHHHHHHHHHHHCCEEEEEECCEEEECCCCEEEHHHHHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]