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The map label for this gene is rocF

Identifier: 225686661

GI number: 225686661

Start: 859948

End: 860868

Strand: Reverse

Name: rocF

Synonym: BMEA_B0881

Alternate gene names: 225686661

Gene position: 860868-859948 (Counterclockwise)

Preceding gene: 225686663

Following gene: 225686660

Centisome position: 72.62

GC content: 59.83

Gene sequence:

>921_bases
ATGCATTGTAAGATTCTGGGGCTGCCCGTTCAGGAAGGCACTGGCCGCAAGGGCTGTAATATGGGGCCTGATTCCTATCG
TGCGGCCGGGATTGCCGATGCCATAAGGGAACTTGGGCACGAGTGCACAGATTTGGGCAATCTGGCGCCTGCCGCCCAGC
GCCCGCTACAGCATCCGAACCATGCAATCAAGGCGCTTCCATATGCCGTTGCCTGGATCGAAGCGATCAGCGAAGCGGCC
TATCGCGAAAGTGCGGAAGGGTTCCCGATCTTTCTTGGTGGCGATCACCTTCTGGCAGCGGGCACGGTTCCCGGTATTGC
GCGCCGCGCCGCTGAAAAGGGGCGCAAGCAATTCGTGCTCTGGCTCGATGCGCATACGGATTTCCATACGCTGGAAACCA
CGACCAGCGGCAATCTTCATGGTACGCCCGTTGCTTATTATACCGGTCAGAAGGGCTTTGAGGGCTATTTCCCCAAGCTT
GCAGCGCCGATCGATCCGCATAATGTCTGCATGTTGGGCATTCGCAGCGTCGATCCGGCTGAGCGGGAAGCGGTCAAGAA
AACAGAAGTTATCGTCTATGACATGCGGCTGATCGACGAGCATGGTGTTGCCGCCCTGCTGCGCCGGTTTCTGGAGCGCG
TGAAGGCGGAAGACGGGCTGTTGCATGTGAGCCTTGATGTCGATTTTCTCGATCCCTCCATCGCGCCGGCCGTGGGTACG
ACGGTGCCTGGCGGCGCGACCTTCCGTGAGGCGCATCTCATCATGGAGATGCTGCACGACAGCGGGCTGGTGACGAGCCT
CGATCTCGTTGAACTCAATCCCTTTCTTGATGAGCGCGGCCGCACGGCCGCCGTCATGGTGGACCTGATGGCGAGCCTTC
TGGGCCGCAGCGTCATGGACCGCCCGACCATCAGCTATTGA

Upstream 100 bases:

>100_bases
ATTCTGATAAACCAAACCGAGAAAATTGCCAATCCGGTTGGTTCACATCGCCAAGCATAAATGGTCAATTTTGATACAGA
TATTAGAAGGAATCCAATTT

Downstream 100 bases:

>100_bases
CGTGGCCCATGTGGCTGCCAAATGCTCAAGGAGCAATGATGACCCAACCGAACCTCAATATCGTTCCTTTCGTCAGCGTC
GATCATATGATGAAGCTGGT

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MHCKILGLPVQEGTGRKGCNMGPDSYRAAGIADAIRELGHECTDLGNLAPAAQRPLQHPNHAIKALPYAVAWIEAISEAA
YRESAEGFPIFLGGDHLLAAGTVPGIARRAAEKGRKQFVLWLDAHTDFHTLETTTSGNLHGTPVAYYTGQKGFEGYFPKL
AAPIDPHNVCMLGIRSVDPAEREAVKKTEVIVYDMRLIDEHGVAALLRRFLERVKAEDGLLHVSLDVDFLDPSIAPAVGT
TVPGGATFREAHLIMEMLHDSGLVTSLDLVELNPFLDERGRTAAVMVDLMASLLGRSVMDRPTISY

Sequences:

>Translated_306_residues
MHCKILGLPVQEGTGRKGCNMGPDSYRAAGIADAIRELGHECTDLGNLAPAAQRPLQHPNHAIKALPYAVAWIEAISEAA
YRESAEGFPIFLGGDHLLAAGTVPGIARRAAEKGRKQFVLWLDAHTDFHTLETTTSGNLHGTPVAYYTGQKGFEGYFPKL
AAPIDPHNVCMLGIRSVDPAEREAVKKTEVIVYDMRLIDEHGVAALLRRFLERVKAEDGLLHVSLDVDFLDPSIAPAVGT
TVPGGATFREAHLIMEMLHDSGLVTSLDLVELNPFLDERGRTAAVMVDLMASLLGRSVMDRPTISY
>Mature_306_residues
MHCKILGLPVQEGTGRKGCNMGPDSYRAAGIADAIRELGHECTDLGNLAPAAQRPLQHPNHAIKALPYAVAWIEAISEAA
YRESAEGFPIFLGGDHLLAAGTVPGIARRAAEKGRKQFVLWLDAHTDFHTLETTTSGNLHGTPVAYYTGQKGFEGYFPKL
AAPIDPHNVCMLGIRSVDPAEREAVKKTEVIVYDMRLIDEHGVAALLRRFLERVKAEDGLLHVSLDVDFLDPSIAPAVGT
TVPGGATFREAHLIMEMLHDSGLVTSLDLVELNPFLDERGRTAAVMVDLMASLLGRSVMDRPTISY

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family

Homologues:

Organism=Homo sapiens, GI4502215, Length=307, Percent_Identity=34.8534201954397, Blast_Score=168, Evalue=6e-42,
Organism=Homo sapiens, GI10947139, Length=304, Percent_Identity=34.2105263157895, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71996843, Length=226, Percent_Identity=30.9734513274336, Blast_Score=96, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6325146, Length=199, Percent_Identity=36.6834170854271, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24638886, Length=308, Percent_Identity=30.5194805194805, Blast_Score=128, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGI_BRUAB (P0A2Y1)

Other databases:

- EMBL:   U57319
- EMBL:   AE017224
- RefSeq:   YP_223125.1
- ProteinModelPortal:   P0A2Y1
- SMR:   P0A2Y1
- GeneID:   3341875
- GenomeReviews:   AE017224_GR
- KEGG:   bmb:BruAb2_0333
- HOGENOM:   HBG391953
- OMA:   CMEMIAD
- PhylomeDB:   P0A2Y1
- ProtClustDB:   CLSK861991
- BioCyc:   BABO262698:BRUAB2_0333-MONOMER
- BRENDA:   3.5.3.1
- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855
- Gene3D:   G3DSA:3.40.800.10
- PANTHER:   PTHR11358:SF2
- PANTHER:   PTHR11358
- PRINTS:   PR00116
- TIGRFAMs:   TIGR01229

Pfam domain/function: PF00491 Arginase

EC number: =3.5.3.1

Molecular weight: Translated: 33182; Mature: 33182

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS01053 ARGINASE_1; PS51409 ARGINASE_2; PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: BINDING 178-178 BINDING 271-271

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCKILGLPVQEGTGRKGCNMGPDSYRAAGIADAIRELGHECTDLGNLAPAAQRPLQHPN
CCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
HAIKALPYAVAWIEAISEAAYRESAEGFPIFLGGDHLLAAGTVPGIARRAAEKGRKQFVL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCHHHHHHHHHCCCEEEEE
WLDAHTDFHTLETTTSGNLHGTPVAYYTGQKGFEGYFPKLAAPIDPHNVCMLGIRSVDPA
EEECCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHH
EREAVKKTEVIVYDMRLIDEHGVAALLRRFLERVKAEDGLLHVSLDVDFLDPSIAPAVGT
HHHHHHHHHEEEEEEHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCC
TVPGGATFREAHLIMEMLHDSGLVTSLDLVELNPFLDERGRTAAVMVDLMASLLGRSVMD
CCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHC
RPTISY
CCCCCC
>Mature Secondary Structure
MHCKILGLPVQEGTGRKGCNMGPDSYRAAGIADAIRELGHECTDLGNLAPAAQRPLQHPN
CCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCC
HAIKALPYAVAWIEAISEAAYRESAEGFPIFLGGDHLLAAGTVPGIARRAAEKGRKQFVL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCHHHHHHHHHCCCEEEEE
WLDAHTDFHTLETTTSGNLHGTPVAYYTGQKGFEGYFPKLAAPIDPHNVCMLGIRSVDPA
EEECCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHH
EREAVKKTEVIVYDMRLIDEHGVAALLRRFLERVKAEDGLLHVSLDVDFLDPSIAPAVGT
HHHHHHHHHEEEEEEHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCC
TVPGGATFREAHLIMEMLHDSGLVTSLDLVELNPFLDERGRTAAVMVDLMASLLGRSVMD
CCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHC
RPTISY
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9375792