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The map label for this gene is patA [H]

Identifier: 225686613

GI number: 225686613

Start: 815350

End: 816804

Strand: Reverse

Name: patA [H]

Synonym: BMEA_B0830

Alternate gene names: 225686613

Gene position: 816804-815350 (Counterclockwise)

Preceding gene: 225686614

Following gene: 225686610

Centisome position: 68.9

GC content: 57.39

Gene sequence:

>1455_bases
ATGAAAAGCACGATTCATTCCGAAGGCGCCGCCGTGTCGGCAAGTGTTGCCAATCACACGCCGAAGCCGCCGCTTTTAAG
CGTCGATGACGCCAAGGCGCTCGACCTGCCGCGCATGACGGAACTTTTCACCGCGCATCTCAACCCCGGCCAGCTTCATT
TCATGAAGCTTCTGGGCTTCCACAAGGTGAAGGTGGAGCGCGCTGAAGGCATGTATTATTACGACCAGAACGGTCGCAGG
ATACTGGATTTCTTCGGCGGTTTCGGCTCGCTGGCCTTCGGCCACAATCACCCGCGCATCATCGCGGCGCGGCGCAAGTT
TCAGGAAGAACTGCGCCATGAGATCGCAATCGCCTTCATGTCGCAATATGCAGCGGCACTTGCCTATGACCTTGCCGCCT
GCTCGCCGGGTGATCTCGACATGGTATTCCTTGGGTCTTCCGGTTCTGAAGCCATGGAAGCGGCCATCAAGGTTGCTGAA
CGCGCCGCAGGGCCGAAAAAGCCCAAGATCGTCTATGCCGAGAATTCCTTCCACGGCAAGACCAAGGGGGTGCTCTCCAT
CACCGATGGCGGGCTTTACCGAGGCGAATTCAAGCTGGTGGACAATACGGTCCGTGTGCCTTTCGGCGATATCACGGCGA
TTGAGAACGCCTTTCGCAGCGACCCGGAAATCGGCACTATCGTCCTGGAAACGGTGCAGGGTGGCTGTGGCATCATTCAG
GCGGATGCCGAATTCTGGCAGAAGCTGCGCCAGCTTTGCGACCGGTATGGTGTGATCTGGGTGGCGGATGAAGTGCAGTG
CGGCTTTGGCCGTACTGGAAAGTTCTACGCCTTTGAGCATTACGGCGTTATCCCGGATGTGACGGCTCTGGCAAAGTCTC
TGGGCGGCGGCAAGGCCGCAATGGCGGCCATGATCGCCCGGCGCGATATTTATATGAAGGCCTATGGCACGCCGAAGACG
GCGATGATCCACGCCATGGCAACGTTCGGCGGTATTGGCGAGGCCTGCATTACCGCCATCGAGGCGGTCAATATTCTCTA
TGATGAACAGCTCATCGATAACTCCGCCGAGGTTGGCGATTATCTTCTGGAACGGCTGAAAGAATTGCAGGTGCGTTATC
CGGGCCTTTTGAAGGATGTGCGCGGCAAGGGCATGATGGTGGGGCTGGAATTCCACGATTTCTCGCAGGCAATGCCGATG
GTTCTGCGGCCTATGCTCGCCATGCTGGATGACAAGCTGAAAGGCTCGTTTCCGGGCTTCATCGGCAGCCATCTGCTGCG
CGATCACGGCGTTCTCGTTGCCTTTACCGAATATAACCGCAATGTCATCCGCCTTGAGCCGCCGCTCATCTGCCAACGTG
CCCATGTGGACGAGTTCATCAAGGCGCTGGACGAAGTCCTGTCACGCGGGATCGTGAAAATCGTCAAGGACTTTATCAAG
GCGCAGATCAAGTAA

Upstream 100 bases:

>100_bases
GAAGACATGCTGATCGCTGCCTATAGTGAATATCGCAAGAAGAAGGCCGGCGGCGCTGAAAACCGCCTGAGCCCGTCAAA
AGCGGCCTGAGGAAGAAACC

Downstream 100 bases:

>100_bases
ACCCGGTCGGGATTAGAGCGCATCCCGAAAAGTGTGAAACGGTTTTCGGAAAAGATGCGCGTCAAAACAAAGGATTAGAG
CGCCGATCTGATTCAATCAG

Product: Putrescine aminotransferase

Products: NA

Alternate protein names: Putrescine--2-oxoglutaric acid transaminase; PAT; PATase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MKSTIHSEGAAVSASVANHTPKPPLLSVDDAKALDLPRMTELFTAHLNPGQLHFMKLLGFHKVKVERAEGMYYYDQNGRR
ILDFFGGFGSLAFGHNHPRIIAARRKFQEELRHEIAIAFMSQYAAALAYDLAACSPGDLDMVFLGSSGSEAMEAAIKVAE
RAAGPKKPKIVYAENSFHGKTKGVLSITDGGLYRGEFKLVDNTVRVPFGDITAIENAFRSDPEIGTIVLETVQGGCGIIQ
ADAEFWQKLRQLCDRYGVIWVADEVQCGFGRTGKFYAFEHYGVIPDVTALAKSLGGGKAAMAAMIARRDIYMKAYGTPKT
AMIHAMATFGGIGEACITAIEAVNILYDEQLIDNSAEVGDYLLERLKELQVRYPGLLKDVRGKGMMVGLEFHDFSQAMPM
VLRPMLAMLDDKLKGSFPGFIGSHLLRDHGVLVAFTEYNRNVIRLEPPLICQRAHVDEFIKALDEVLSRGIVKIVKDFIK
AQIK

Sequences:

>Translated_484_residues
MKSTIHSEGAAVSASVANHTPKPPLLSVDDAKALDLPRMTELFTAHLNPGQLHFMKLLGFHKVKVERAEGMYYYDQNGRR
ILDFFGGFGSLAFGHNHPRIIAARRKFQEELRHEIAIAFMSQYAAALAYDLAACSPGDLDMVFLGSSGSEAMEAAIKVAE
RAAGPKKPKIVYAENSFHGKTKGVLSITDGGLYRGEFKLVDNTVRVPFGDITAIENAFRSDPEIGTIVLETVQGGCGIIQ
ADAEFWQKLRQLCDRYGVIWVADEVQCGFGRTGKFYAFEHYGVIPDVTALAKSLGGGKAAMAAMIARRDIYMKAYGTPKT
AMIHAMATFGGIGEACITAIEAVNILYDEQLIDNSAEVGDYLLERLKELQVRYPGLLKDVRGKGMMVGLEFHDFSQAMPM
VLRPMLAMLDDKLKGSFPGFIGSHLLRDHGVLVAFTEYNRNVIRLEPPLICQRAHVDEFIKALDEVLSRGIVKIVKDFIK
AQIK
>Mature_484_residues
MKSTIHSEGAAVSASVANHTPKPPLLSVDDAKALDLPRMTELFTAHLNPGQLHFMKLLGFHKVKVERAEGMYYYDQNGRR
ILDFFGGFGSLAFGHNHPRIIAARRKFQEELRHEIAIAFMSQYAAALAYDLAACSPGDLDMVFLGSSGSEAMEAAIKVAE
RAAGPKKPKIVYAENSFHGKTKGVLSITDGGLYRGEFKLVDNTVRVPFGDITAIENAFRSDPEIGTIVLETVQGGCGIIQ
ADAEFWQKLRQLCDRYGVIWVADEVQCGFGRTGKFYAFEHYGVIPDVTALAKSLGGGKAAMAAMIARRDIYMKAYGTPKT
AMIHAMATFGGIGEACITAIEAVNILYDEQLIDNSAEVGDYLLERLKELQVRYPGLLKDVRGKGMMVGLEFHDFSQAMPM
VLRPMLAMLDDKLKGSFPGFIGSHLLRDHGVLVAFTEYNRNVIRLEPPLICQRAHVDEFIKALDEVLSRGIVKIVKDFIK
AQIK

Specific function: Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithi

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=474, Percent_Identity=26.7932489451477, Blast_Score=156, Evalue=5e-38,
Organism=Homo sapiens, GI13994255, Length=401, Percent_Identity=28.927680798005, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI37574042, Length=433, Percent_Identity=25.1732101616628, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI226442705, Length=433, Percent_Identity=24.7113163972286, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI24119277, Length=430, Percent_Identity=24.4186046511628, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI284507298, Length=332, Percent_Identity=29.2168674698795, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI226442709, Length=403, Percent_Identity=24.8138957816377, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI188536080, Length=457, Percent_Identity=22.5382932166302, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI38679950, Length=457, Percent_Identity=22.5382932166302, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI38679946, Length=457, Percent_Identity=22.5382932166302, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI145693181, Length=454, Percent_Identity=32.3788546255507, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789759, Length=409, Percent_Identity=30.8068459657702, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1789016, Length=426, Percent_Identity=30.0469483568075, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1788044, Length=416, Percent_Identity=29.8076923076923, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1787560, Length=420, Percent_Identity=29.7619047619048, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1786991, Length=269, Percent_Identity=31.2267657992565, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786349, Length=389, Percent_Identity=28.2776349614396, Blast_Score=124, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=426, Percent_Identity=28.4037558685446, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=27.5229357798165, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI25144274, Length=312, Percent_Identity=30.1282051282051, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71992977, Length=442, Percent_Identity=24.4343891402715, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17541228, Length=443, Percent_Identity=24.6049661399549, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323470, Length=415, Percent_Identity=29.3975903614458, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6324432, Length=335, Percent_Identity=31.3432835820896, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6324386, Length=314, Percent_Identity=24.5222929936306, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28574759, Length=466, Percent_Identity=29.6137339055794, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI161085790, Length=473, Percent_Identity=28.7526427061311, Blast_Score=159, Evalue=6e-39,
Organism=Drosophila melanogaster, GI21357415, Length=413, Percent_Identity=26.634382566586, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI21356575, Length=440, Percent_Identity=25.9090909090909, Blast_Score=133, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR017747
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.82 [H]

Molecular weight: Translated: 53313; Mature: 53313

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTIHSEGAAVSASVANHTPKPPLLSVDDAKALDLPRMTELFTAHLNPGQLHFMKLLGF
CCCCCCCCCCEEEEHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCH
HKVKVERAEGMYYYDQNGRRILDFFGGFGSLAFGHNHPRIIAARRKFQEELRHEIAIAFM
HHEEEECCCCEEEECCCCCEEHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
SQYAAALAYDLAACSPGDLDMVFLGSSGSEAMEAAIKVAERAAGPKKPKIVYAENSFHGK
HHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
TKGVLSITDGGLYRGEFKLVDNTVRVPFGDITAIENAFRSDPEIGTIVLETVQGGCGIIQ
CCCEEEEECCCEEECEEEEECCEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCEEE
ADAEFWQKLRQLCDRYGVIWVADEVQCGFGRTGKFYAFEHYGVIPDVTALAKSLGGGKAA
CCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCHHH
MAAMIARRDIYMKAYGTPKTAMIHAMATFGGIGEACITAIEAVNILYDEQLIDNSAEVGD
HHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YLLERLKELQVRYPGLLKDVRGKGMMVGLEFHDFSQAMPMVLRPMLAMLDDKLKGSFPGF
HHHHHHHHHHHCCCCHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
IGSHLLRDHGVLVAFTEYNRNVIRLEPPLICQRAHVDEFIKALDEVLSRGIVKIVKDFIK
HHHHHHHCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQIK
HCCC
>Mature Secondary Structure
MKSTIHSEGAAVSASVANHTPKPPLLSVDDAKALDLPRMTELFTAHLNPGQLHFMKLLGF
CCCCCCCCCCEEEEHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCH
HKVKVERAEGMYYYDQNGRRILDFFGGFGSLAFGHNHPRIIAARRKFQEELRHEIAIAFM
HHEEEECCCCEEEECCCCCEEHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
SQYAAALAYDLAACSPGDLDMVFLGSSGSEAMEAAIKVAERAAGPKKPKIVYAENSFHGK
HHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
TKGVLSITDGGLYRGEFKLVDNTVRVPFGDITAIENAFRSDPEIGTIVLETVQGGCGIIQ
CCCEEEEECCCEEECEEEEECCEEECCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCEEE
ADAEFWQKLRQLCDRYGVIWVADEVQCGFGRTGKFYAFEHYGVIPDVTALAKSLGGGKAA
CCHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCHHH
MAAMIARRDIYMKAYGTPKTAMIHAMATFGGIGEACITAIEAVNILYDEQLIDNSAEVGD
HHHHHHHHHEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
YLLERLKELQVRYPGLLKDVRGKGMMVGLEFHDFSQAMPMVLRPMLAMLDDKLKGSFPGF
HHHHHHHHHHHCCCCHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
IGSHLLRDHGVLVAFTEYNRNVIRLEPPLICQRAHVDEFIKALDEVLSRGIVKIVKDFIK
HHHHHHHCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQIK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA