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The map label for this gene is galE [C]

Identifier: 225686614

GI number: 225686614

Start: 816815

End: 817825

Strand: Reverse

Name: galE [C]

Synonym: BMEA_B0831

Alternate gene names: 225686614

Gene position: 817825-816815 (Counterclockwise)

Preceding gene: 225686615

Following gene: 225686613

Centisome position: 68.98

GC content: 55.79

Gene sequence:

>1011_bases
ATGAGGCATATTATTTTCGGCGGTGACGGTTTTGTCGGGCGTTATCTCGCGCCCCAATTGCTGGCCGATGGCCATGAGGT
GATCGTCGCCGATATCGTCAAAAGCGATCTTGCGCATTATGGCGATGCGACCTTCGTTCATACGGATGTGACGGACCCGG
AATCGATCCGCAAGCTTGGCATTCGCGCCGATGACATGGTTTATAATCTCTCGGCCAAGATGCTTTCGCCCATTCAGGTC
CGCGCCAAGCGGCATGATTTCTTCTTCCCCGTGAACTATTACGGCACAGAGAACATCATAAAGGCGATGGATGCAGCGGG
GGCAAAAAAGCTGGTCCATTTCACCACCGATATGGTCTATGGCCACACCTATGTCTGGCCGCAAAAGGAAGATCACCCCT
GCAAGCCGCTCGGAGAATATGGGCTTTCCAAGCTGAAAACCGAGGAACTGGCGGCGCAATGGCGCACGCGCGGCATGAAT
ATCTCACTCTTCCGCCCGCGCCTCATCATCGGCCCCGGACGGCTTGGAATTCTCGAAAAGCTGTTCAAGCTGATAGACAA
TAACCTGCCCGTGCCGATGATCGGCTCCGGCAAGAACCCCTATCAGTTTATTTCGGTGTTCGATTGCGCATCTGCCGCTC
GCGCGGCCTTCAAGGCGGGCGTGCCGAACGAGGTGTATAATCTCGGTTCGCTCAATCTGCCGCCGGTGCGCAAGCTTCTG
GGCGATCTGATCAAACATGCGGGTTCAAAATCGATGCTGCTTCCCACGCCTGCCTGGGCGGTGAAGCGTACGCTTGATTT
CCTCGACTGGCTTAACATGCCGCTCATGGACCCGGAGCAATATCTGATCGCCGATGAGATGTGCGTTCTCGACGTTTCCA
AGGGCGAGCGTGAACTGGGCTGGATTCCGCAATATCGCGATGAAGACATGCTGATCGCTGCCTATAGTGAATATCGCAAG
AAGAAGGCCGGCGGCGCTGAAAACCGCCTGAGCCCGTCAAAAGCGGCCTGA

Upstream 100 bases:

>100_bases
GGTGCGGGAAGCCGATAAGGCAGTCACGGTACAGGAGCAGGCGCAGCTATAGGTTGTTTGCTCCATTTTCATTACGTCCA
TTCAAAGTGCGGGGTTCCAG

Downstream 100 bases:

>100_bases
GGAAGAAACCATGAAAAGCACGATTCATTCCGAAGGCGCCGCCGTGTCGGCAAGTGTTGCCAATCACACGCCGAAGCCGC
CGCTTTTAAGCGTCGATGAC

Product: UDP-glucuronic acid decarboxylase 1

Products: dTDP-4-dehydro-6-deoxy-D-glucose; H2O

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MRHIIFGGDGFVGRYLAPQLLADGHEVIVADIVKSDLAHYGDATFVHTDVTDPESIRKLGIRADDMVYNLSAKMLSPIQV
RAKRHDFFFPVNYYGTENIIKAMDAAGAKKLVHFTTDMVYGHTYVWPQKEDHPCKPLGEYGLSKLKTEELAAQWRTRGMN
ISLFRPRLIIGPGRLGILEKLFKLIDNNLPVPMIGSGKNPYQFISVFDCASAARAAFKAGVPNEVYNLGSLNLPPVRKLL
GDLIKHAGSKSMLLPTPAWAVKRTLDFLDWLNMPLMDPEQYLIADEMCVLDVSKGERELGWIPQYRDEDMLIAAYSEYRK
KKAGGAENRLSPSKAA

Sequences:

>Translated_336_residues
MRHIIFGGDGFVGRYLAPQLLADGHEVIVADIVKSDLAHYGDATFVHTDVTDPESIRKLGIRADDMVYNLSAKMLSPIQV
RAKRHDFFFPVNYYGTENIIKAMDAAGAKKLVHFTTDMVYGHTYVWPQKEDHPCKPLGEYGLSKLKTEELAAQWRTRGMN
ISLFRPRLIIGPGRLGILEKLFKLIDNNLPVPMIGSGKNPYQFISVFDCASAARAAFKAGVPNEVYNLGSLNLPPVRKLL
GDLIKHAGSKSMLLPTPAWAVKRTLDFLDWLNMPLMDPEQYLIADEMCVLDVSKGERELGWIPQYRDEDMLIAAYSEYRK
KKAGGAENRLSPSKAA
>Mature_336_residues
MRHIIFGGDGFVGRYLAPQLLADGHEVIVADIVKSDLAHYGDATFVHTDVTDPESIRKLGIRADDMVYNLSAKMLSPIQV
RAKRHDFFFPVNYYGTENIIKAMDAAGAKKLVHFTTDMVYGHTYVWPQKEDHPCKPLGEYGLSKLKTEELAAQWRTRGMN
ISLFRPRLIIGPGRLGILEKLFKLIDNNLPVPMIGSGKNPYQFISVFDCASAARAAFKAGVPNEVYNLGSLNLPPVRKLL
GDLIKHAGSKSMLLPTPAWAVKRTLDFLDWLNMPLMDPEQYLIADEMCVLDVSKGERELGWIPQYRDEDMLIAAYSEYRK
KKAGGAENRLSPSKAA

Specific function: Putative nucleotide sugar epimerase/dehydrogenase [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7657641, Length=269, Percent_Identity=24.1635687732342, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: 4.2.1.46

Molecular weight: Translated: 37612; Mature: 37612

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHIIFGGDGFVGRYLAPQLLADGHEVIVADIVKSDLAHYGDATFVHTDVTDPESIRKLG
CCEEEECCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHC
IRADDMVYNLSAKMLSPIQVRAKRHDFFFPVNYYGTENIIKAMDAAGAKKLVHFTTDMVY
CCHHHHEEECHHHHCCHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHC
GHTYVWPQKEDHPCKPLGEYGLSKLKTEELAAQWRTRGMNISLFRPRLIIGPGRLGILEK
CCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCHHHHHH
LFKLIDNNLPVPMIGSGKNPYQFISVFDCASAARAAFKAGVPNEVYNLGSLNLPPVRKLL
HHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHH
GDLIKHAGSKSMLLPTPAWAVKRTLDFLDWLNMPLMDPEQYLIADEMCVLDVSKGERELG
HHHHHHCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEECCCCCCCCC
WIPQYRDEDMLIAAYSEYRKKKAGGAENRLSPSKAA
CCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRHIIFGGDGFVGRYLAPQLLADGHEVIVADIVKSDLAHYGDATFVHTDVTDPESIRKLG
CCEEEECCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHC
IRADDMVYNLSAKMLSPIQVRAKRHDFFFPVNYYGTENIIKAMDAAGAKKLVHFTTDMVY
CCHHHHEEECHHHHCCHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHC
GHTYVWPQKEDHPCKPLGEYGLSKLKTEELAAQWRTRGMNISLFRPRLIIGPGRLGILEK
CCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCHHHHHH
LFKLIDNNLPVPMIGSGKNPYQFISVFDCASAARAAFKAGVPNEVYNLGSLNLPPVRKLL
HHHHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHH
GDLIKHAGSKSMLLPTPAWAVKRTLDFLDWLNMPLMDPEQYLIADEMCVLDVSKGERELG
HHHHHHCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCEEEEECCCCCCCCC
WIPQYRDEDMLIAAYSEYRKKKAGGAENRLSPSKAA
CCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDPglucose

Specific reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-D-glucose + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]