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The map label for this gene is mmgC [H]

Identifier: 225686562

GI number: 225686562

Start: 757442

End: 759235

Strand: Reverse

Name: mmgC [H]

Synonym: BMEA_B0774

Alternate gene names: 225686562

Gene position: 759235-757442 (Counterclockwise)

Preceding gene: 225686563

Following gene: 225686561

Centisome position: 64.04

GC content: 58.19

Gene sequence:

>1794_bases
ATGCCAAGTTATCGCGCGCCGGTTGAGGATACGAATTTCGTTCTCAACGACGTTTTGAATTATCAGCGTTACAACAATCT
GCCGGGCTTTGCCGAAGCAGCGCCCGATGTCGTCGAGGCAATCCTGTCGGAAGGCGCAAAGCTGGCTGAAGGCACGCTCT
TCCCCGTCAACCAGACGGCGGATCGCGAAGGCTGCACCCGTCATGCGGATGGCTCCGTCACCACGCCCAAGGGCTACAAG
GAAGCCTATAATCTCTATCGCGAAGGCGGCTGGCTCGGCCTTGCGGTGCCGGAGCAATATGGCGGGCAGGGGCTTCCCTA
TCTGCTGCACACTGCCGTCGGCGAATATATGTCGTCGGCCAATATGGCGCTCACCATGTATCCGGGCCTGACGCAAGGCG
CGATCGCCGCGATCCTCACCCACGGCACCGACGAGCAGAAGGACACCTATCTGCCGAAGATGGTGGAGGGCACCTGGACC
GGCACGATGAACCTGACCGAGCCGCATTGCGGCACCGATCTGGGGCTCCTGCGCACCAGCGCTGTGCCGCAAGCCGATGG
CACTTACAAGATCTCCGGCCAGAAGATTTTTATCTCGGCTGGCGAACACGACATGTCGGAAAACATCATCCATCTGGTGC
TGGCCCGTATCGAGGGCGCGCCGGAAGGCGTGAAGGGTATTTCGCTGTTCATCGTGCCGAAGTTCATTCTTGATGAAAAC
GGCAATCCCGGCACCCGCAATGGCGTTTCCTGCGGTTCCATCGAAGAAAAGATGGGCATCCATGGCAATGCCACCTGCGT
CATGAATTATGATGAGGCGACCGGCTATCTGATCGGCGAGGCCAACAAGGGCCTGCGCGCCATGTTCACCATGATGAACG
AAGCGCGCCTCGGTGTGGCCTTGCAGGGCCTTTCCATCGCCGAAACGGCCTATCAGAACGCGGTGATCTATGCGCGCGAA
CGCATTCAGGGCCGCGCGCTTTCAGGTGCTGTAGCGCCGGAAAAGAAAGCCGATCCGATCATCGTCCATCCCGATATCCG
CCGCAACCTCATGAATATCCGCGCTTTCAACGAGGCCGGTCGTGCGCTTATCCTGTGGATTGCGCTTCATTCCGATATTG
CGCATCGCTCTGGTGACGAGGCCGAACGTCAGGCTGCCGATGATCTGGTCGGCCTTTTGACGCCGGTTTTGAAGGGCGTT
CTGACAGACAAGGGTTTTGAACATGCCGTCATGGCGCAGCAGGTTTTCGGCGGCCATGGCTATATCGAAGAACAGGGCAT
GAGCCAGTATGTGCGCGATGCGCGCATTGCCATGATCTATGAAGGTGCGAACGGCATTCAGGCGCTCGACCTCGTCGGCC
GTAAGCTGGCGCTGAACGGTGGCCGCGCCATCACTGCCTTCTTCAAGGAAGTGGGCGAGTTCTGCGAAACCAATCGCGAA
AATGAAAAGCTCTCCTTCTTCACCAAATATCTGAAGAAGGGCGTCAACGACCTTCAGGCCGCAACCATGTGGCTGATGCA
GAATGCAATGGCCAAGCCCGATAATGCGGGTGCTGCCTCCAATGATTACATGCATCTCTTCGGTCTGGTGGCGCTGGGCT
ATATGTGGGCGCGCATGGCCAAGGTCGCAGAAGAAAAGCTGGCTGCGGGTGAAGGCAACAAGGCGTTTTTCGAGGCAAAA
CTCGTCACCGCGCGCTATTATTTCGAGCGGATCATGCCCGAAAGCGTTACGCATCTGGCGCGCATCCAGTCGGGTGCGGA
TAGCATGATGGCGCTTAACGCGGGCACATTCTGA

Upstream 100 bases:

>100_bases
GCGATTCCGCCCTTATGTGACCAATCATGCATGAACGTGGTTGGAAGCATTTTCCGCCAAGGGCGAAAAATGCGCAAGGT
TATTGATTTGGAGGATCTCG

Downstream 100 bases:

>100_bases
GGCTTTTTGATTTGAGCCGGTGCCGGGGGCACCGGCGGGCCAAATTTGGCTGGAAGGAGCAAACATGGCTGAGGCTTATA
TTTACGATCACGTGCGCACG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 597; Mature: 596

Protein sequence:

>597_residues
MPSYRAPVEDTNFVLNDVLNYQRYNNLPGFAEAAPDVVEAILSEGAKLAEGTLFPVNQTADREGCTRHADGSVTTPKGYK
EAYNLYREGGWLGLAVPEQYGGQGLPYLLHTAVGEYMSSANMALTMYPGLTQGAIAAILTHGTDEQKDTYLPKMVEGTWT
GTMNLTEPHCGTDLGLLRTSAVPQADGTYKISGQKIFISAGEHDMSENIIHLVLARIEGAPEGVKGISLFIVPKFILDEN
GNPGTRNGVSCGSIEEKMGIHGNATCVMNYDEATGYLIGEANKGLRAMFTMMNEARLGVALQGLSIAETAYQNAVIYARE
RIQGRALSGAVAPEKKADPIIVHPDIRRNLMNIRAFNEAGRALILWIALHSDIAHRSGDEAERQAADDLVGLLTPVLKGV
LTDKGFEHAVMAQQVFGGHGYIEEQGMSQYVRDARIAMIYEGANGIQALDLVGRKLALNGGRAITAFFKEVGEFCETNRE
NEKLSFFTKYLKKGVNDLQAATMWLMQNAMAKPDNAGAASNDYMHLFGLVALGYMWARMAKVAEEKLAAGEGNKAFFEAK
LVTARYYFERIMPESVTHLARIQSGADSMMALNAGTF

Sequences:

>Translated_597_residues
MPSYRAPVEDTNFVLNDVLNYQRYNNLPGFAEAAPDVVEAILSEGAKLAEGTLFPVNQTADREGCTRHADGSVTTPKGYK
EAYNLYREGGWLGLAVPEQYGGQGLPYLLHTAVGEYMSSANMALTMYPGLTQGAIAAILTHGTDEQKDTYLPKMVEGTWT
GTMNLTEPHCGTDLGLLRTSAVPQADGTYKISGQKIFISAGEHDMSENIIHLVLARIEGAPEGVKGISLFIVPKFILDEN
GNPGTRNGVSCGSIEEKMGIHGNATCVMNYDEATGYLIGEANKGLRAMFTMMNEARLGVALQGLSIAETAYQNAVIYARE
RIQGRALSGAVAPEKKADPIIVHPDIRRNLMNIRAFNEAGRALILWIALHSDIAHRSGDEAERQAADDLVGLLTPVLKGV
LTDKGFEHAVMAQQVFGGHGYIEEQGMSQYVRDARIAMIYEGANGIQALDLVGRKLALNGGRAITAFFKEVGEFCETNRE
NEKLSFFTKYLKKGVNDLQAATMWLMQNAMAKPDNAGAASNDYMHLFGLVALGYMWARMAKVAEEKLAAGEGNKAFFEAK
LVTARYYFERIMPESVTHLARIQSGADSMMALNAGTF
>Mature_596_residues
PSYRAPVEDTNFVLNDVLNYQRYNNLPGFAEAAPDVVEAILSEGAKLAEGTLFPVNQTADREGCTRHADGSVTTPKGYKE
AYNLYREGGWLGLAVPEQYGGQGLPYLLHTAVGEYMSSANMALTMYPGLTQGAIAAILTHGTDEQKDTYLPKMVEGTWTG
TMNLTEPHCGTDLGLLRTSAVPQADGTYKISGQKIFISAGEHDMSENIIHLVLARIEGAPEGVKGISLFIVPKFILDENG
NPGTRNGVSCGSIEEKMGIHGNATCVMNYDEATGYLIGEANKGLRAMFTMMNEARLGVALQGLSIAETAYQNAVIYARER
IQGRALSGAVAPEKKADPIIVHPDIRRNLMNIRAFNEAGRALILWIALHSDIAHRSGDEAERQAADDLVGLLTPVLKGVL
TDKGFEHAVMAQQVFGGHGYIEEQGMSQYVRDARIAMIYEGANGIQALDLVGRKLALNGGRAITAFFKEVGEFCETNREN
EKLSFFTKYLKKGVNDLQAATMWLMQNAMAKPDNAGAASNDYMHLFGLVALGYMWARMAKVAEEKLAAGEGNKAFFEAKL
VTARYYFERIMPESVTHLARIQSGADSMMALNAGTF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=364, Percent_Identity=27.4725274725275, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4557233, Length=429, Percent_Identity=27.2727272727273, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI7656849, Length=371, Percent_Identity=27.7628032345013, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI226958412, Length=416, Percent_Identity=25.4807692307692, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI226958414, Length=372, Percent_Identity=26.0752688172043, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI76496475, Length=373, Percent_Identity=26.5415549597855, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI4557235, Length=373, Percent_Identity=26.5415549597855, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI4501857, Length=389, Percent_Identity=25.4498714652956, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI21361497, Length=406, Percent_Identity=25.1231527093596, Blast_Score=94, Evalue=4e-19,
Organism=Escherichia coli, GI87082384, Length=336, Percent_Identity=27.6785714285714, Blast_Score=116, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17508101, Length=364, Percent_Identity=27.7472527472527, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71990804, Length=281, Percent_Identity=29.5373665480427, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17533517, Length=426, Percent_Identity=24.1784037558685, Blast_Score=99, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=364, Percent_Identity=24.1758241758242, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985184, Length=371, Percent_Identity=26.1455525606469, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=408, Percent_Identity=24.0196078431373, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=386, Percent_Identity=26.6839378238342, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=383, Percent_Identity=26.1096605744125, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI86563383, Length=416, Percent_Identity=26.4423076923077, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI86563381, Length=414, Percent_Identity=26.0869565217391, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32563615, Length=236, Percent_Identity=25.4237288135593, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=244, Percent_Identity=27.8688524590164, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=370, Percent_Identity=25.1351351351351, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=381, Percent_Identity=22.8346456692913, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=345, Percent_Identity=25.5072463768116, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17551932, Length=382, Percent_Identity=23.0366492146597, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=28.042328042328, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646207, Length=368, Percent_Identity=26.3586956521739, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI21355753, Length=371, Percent_Identity=25.0673854447439, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281363737, Length=372, Percent_Identity=25.8064516129032, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24666513, Length=408, Percent_Identity=24.2647058823529, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19920834, Length=341, Percent_Identity=28.1524926686217, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 64910; Mature: 64779

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSYRAPVEDTNFVLNDVLNYQRYNNLPGFAEAAPDVVEAILSEGAKLAEGTLFPVNQTA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCHHHCCEEECCCCCC
DREGCTRHADGSVTTPKGYKEAYNLYREGGWLGLAVPEQYGGQGLPYLLHTAVGEYMSSA
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHCCCCCHHHHHHHHHHHHHCC
NMALTMYPGLTQGAIAAILTHGTDEQKDTYLPKMVEGTWTGTMNLTEPHCGTDLGLLRTS
CEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCCEECEEECCCCCCCCCHHHHHHC
AVPQADGTYKISGQKIFISAGEHDMSENIIHLVLARIEGAPEGVKGISLFIVPKFILDEN
CCCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHEECCC
GNPGTRNGVSCGSIEEKMGIHGNATCVMNYDEATGYLIGEANKGLRAMFTMMNEARLGVA
CCCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCEE
LQGLSIAETAYQNAVIYARERIQGRALSGAVAPEKKADPIIVHPDIRRNLMNIRAFNEAG
ECCCHHHHHHHHHHHEEEHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCC
RALILWIALHSDIAHRSGDEAERQAADDLVGLLTPVLKGVLTDKGFEHAVMAQQVFGGHG
CEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
YIEEQGMSQYVRDARIAMIYEGANGIQALDLVGRKLALNGGRAITAFFKEVGEFCETNRE
CCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHCHHEEECCCHHHHHHHHHHHHHHHCCCC
NEKLSFFTKYLKKGVNDLQAATMWLMQNAMAKPDNAGAASNDYMHLFGLVALGYMWARMA
CHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KVAEEKLAAGEGNKAFFEAKLVTARYYFERIMPESVTHLARIQSGADSMMALNAGTF
HHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEECCCCC
>Mature Secondary Structure 
PSYRAPVEDTNFVLNDVLNYQRYNNLPGFAEAAPDVVEAILSEGAKLAEGTLFPVNQTA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCHHHCCEEECCCCCC
DREGCTRHADGSVTTPKGYKEAYNLYREGGWLGLAVPEQYGGQGLPYLLHTAVGEYMSSA
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHCCCCCHHHHHHHHHHHHHCC
NMALTMYPGLTQGAIAAILTHGTDEQKDTYLPKMVEGTWTGTMNLTEPHCGTDLGLLRTS
CEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCHHHCCCEECEEECCCCCCCCCHHHHHHC
AVPQADGTYKISGQKIFISAGEHDMSENIIHLVLARIEGAPEGVKGISLFIVPKFILDEN
CCCCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEHEECCC
GNPGTRNGVSCGSIEEKMGIHGNATCVMNYDEATGYLIGEANKGLRAMFTMMNEARLGVA
CCCCCCCCCCCCCHHHHHCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHCCEE
LQGLSIAETAYQNAVIYARERIQGRALSGAVAPEKKADPIIVHPDIRRNLMNIRAFNEAG
ECCCHHHHHHHHHHHEEEHHHHCCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCC
RALILWIALHSDIAHRSGDEAERQAADDLVGLLTPVLKGVLTDKGFEHAVMAQQVFGGHG
CEEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
YIEEQGMSQYVRDARIAMIYEGANGIQALDLVGRKLALNGGRAITAFFKEVGEFCETNRE
CCCHHHHHHHHCCCEEEEEEECCCCCHHHHHHCHHEEECCCHHHHHHHHHHHHHHHCCCC
NEKLSFFTKYLKKGVNDLQAATMWLMQNAMAKPDNAGAASNDYMHLFGLVALGYMWARMA
CHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KVAEEKLAAGEGNKAFFEAKLVTARYYFERIMPESVTHLARIQSGADSMMALNAGTF
HHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]