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The map label for this gene is tlyC [H]

Identifier: 225853582

GI number: 225853582

Start: 2095081

End: 2096199

Strand: Direct

Name: tlyC [H]

Synonym: BMEA_A2216

Alternate gene names: 225853582

Gene position: 2095081-2096199 (Clockwise)

Preceding gene: 225853581

Following gene: 225853583

Centisome position: 98.56

GC content: 59.79

Gene sequence:

>1119_bases
ATGGCTGAACAGACTTTGCACCCTCTGTCCGCTGGCGATAATCGCGGCGAGACCCAAGATTCAGAAGGACAAAGTACGCA
GCGGTCGTCTGTGACCGAGAAGCGTTCCCTTTTGTCGAATATTTTCCCCTTTATGCGCGCGCGCCAGGCATCTTCCCTGC
GCGAAGATCTGGCCGATGCGCTTTCCAGCGCCACCAGCGAGGACGGTGCTGCATTTTCGCCCGAAGAAAAGGCGATGCTG
CACAATATCCTGCGCCTGCGCGAAATCCGCGTCGAGGACGTGATGATTCCCCGCGCCGACGTTGAAGCGGTCGAGATCAC
CACGCCGCTGTGGGAAGTGCTGGAACTTTTTGAAAAATCCGGCCATTCCCGTATGCCGGTCTATGCCGAGACGCTGGATG
ATCCGCGCGGCATGATCCATATCCGCGATGTTTTGAACTATATCACCCGTCAGGCGCGCCAGAAGGCACGGCGGCGCACG
ACGGCGAAATCTGCGGCGACGGAAGTGGCGCCGAAATTCGATATGAGCCGCATCGATCTGGCCAAGACCATCGGCGAGCT
CAATCTCATGCGCAAGGTGCTGTTCGTGCCGCCGTCCATGATGGCAAGCGGATTGATGGCGCGTATGCAGGCCAGCCATA
TCCAGATGGCGCTGGTCATCGATGAATATGGCGGCACCGACGGTCTGGTTTCGCTGGAAGACATTGTTGAAATGGTCGTC
GGCGATATCGAAGACGAACATGACGACGAAGAAATCATGATCGCGGAAGATGCCGATGGCGTTTTCGTGGTCGATGCGCG
CGCCGATCTGGAAGAACTGGCCGCCAGGATCGGCCCGGGCTTCGCAGTGGGCGAGCATGGCGAGGACGTGGACACGGTCG
GTGGCCTTATCTTCTCCGTTCTGGGACGCATCCCGGTGCGCGGTGAAGTGGTTCAGGCCATTCCGGATTATGAATTCCAC
GTATTGGAGGTTGACCCGCGCCGGGTGAAGAAGGTGCGCATCGTGCCGCTTTCCGCTGCCGATCGCCGGCGCCAGCAGCG
CGCTGTGGTTTCGGCCAGGCCGGAAGACCATGCGGCTGATGCGGCGCACGCCGCGCAAAACTCCAAAGAAGCCGGATGA

Upstream 100 bases:

>100_bases
AAGCGGAAGTGATGGAAGCGCGCGAGCGTGAAATCCTTCATGCTCTTGCCATTCCCGACCCTTATGCTGTATCCGATGAG
GACATTAACAACGATTGACC

Downstream 100 bases:

>100_bases
TCGCAAGGCTCGCGGGCAGGATCATTCTTCTTAGCGGCTGGCGTCGCGCGCTGGCCGCTTTTTTGAGTGGCGCTTTCGCA
ACCCTGACCCAGCCGCCTTT

Product: hemolysin C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MAEQTLHPLSAGDNRGETQDSEGQSTQRSSVTEKRSLLSNIFPFMRARQASSLREDLADALSSATSEDGAAFSPEEKAML
HNILRLREIRVEDVMIPRADVEAVEITTPLWEVLELFEKSGHSRMPVYAETLDDPRGMIHIRDVLNYITRQARQKARRRT
TAKSAATEVAPKFDMSRIDLAKTIGELNLMRKVLFVPPSMMASGLMARMQASHIQMALVIDEYGGTDGLVSLEDIVEMVV
GDIEDEHDDEEIMIAEDADGVFVVDARADLEELAARIGPGFAVGEHGEDVDTVGGLIFSVLGRIPVRGEVVQAIPDYEFH
VLEVDPRRVKKVRIVPLSAADRRRQQRAVVSARPEDHAADAAHAAQNSKEAG

Sequences:

>Translated_372_residues
MAEQTLHPLSAGDNRGETQDSEGQSTQRSSVTEKRSLLSNIFPFMRARQASSLREDLADALSSATSEDGAAFSPEEKAML
HNILRLREIRVEDVMIPRADVEAVEITTPLWEVLELFEKSGHSRMPVYAETLDDPRGMIHIRDVLNYITRQARQKARRRT
TAKSAATEVAPKFDMSRIDLAKTIGELNLMRKVLFVPPSMMASGLMARMQASHIQMALVIDEYGGTDGLVSLEDIVEMVV
GDIEDEHDDEEIMIAEDADGVFVVDARADLEELAARIGPGFAVGEHGEDVDTVGGLIFSVLGRIPVRGEVVQAIPDYEFH
VLEVDPRRVKKVRIVPLSAADRRRQQRAVVSARPEDHAADAAHAAQNSKEAG
>Mature_371_residues
AEQTLHPLSAGDNRGETQDSEGQSTQRSSVTEKRSLLSNIFPFMRARQASSLREDLADALSSATSEDGAAFSPEEKAMLH
NILRLREIRVEDVMIPRADVEAVEITTPLWEVLELFEKSGHSRMPVYAETLDDPRGMIHIRDVLNYITRQARQKARRRTT
AKSAATEVAPKFDMSRIDLAKTIGELNLMRKVLFVPPSMMASGLMARMQASHIQMALVIDEYGGTDGLVSLEDIVEMVVG
DIEDEHDDEEIMIAEDADGVFVVDARADLEELAARIGPGFAVGEHGEDVDTVGGLIFSVLGRIPVRGEVVQAIPDYEFHV
LEVDPRRVKKVRIVPLSAADRRRQQRAVVSARPEDHAADAAHAAQNSKEAG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=234, Percent_Identity=27.3504273504274, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1786879, Length=315, Percent_Identity=26.3492063492064, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI87082033, Length=274, Percent_Identity=26.2773722627737, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI145693175, Length=280, Percent_Identity=26.7857142857143, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788119, Length=298, Percent_Identity=24.8322147651007, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 41043; Mature: 40912

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQTLHPLSAGDNRGETQDSEGQSTQRSSVTEKRSLLSNIFPFMRARQASSLREDLADA
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSATSEDGAAFSPEEKAMLHNILRLREIRVEDVMIPRADVEAVEITTPLWEVLELFEKS
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECHHHHHHHHHHHHC
GHSRMPVYAETLDDPRGMIHIRDVLNYITRQARQKARRRTTAKSAATEVAPKFDMSRIDL
CCCCCCCHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AKTIGELNLMRKVLFVPPSMMASGLMARMQASHIQMALVIDEYGGTDGLVSLEDIVEMVV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCEEHHHHHHHHH
GDIEDEHDDEEIMIAEDADGVFVVDARADLEELAARIGPGFAVGEHGEDVDTVGGLIFSV
HCCCCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHCCCCEECCCCCCHHHHHHHHHHH
LGRIPVRGEVVQAIPDYEFHVLEVDPRRVKKVRIVPLSAADRRRQQRAVVSARPEDHAAD
HCCCCCCCHHHHHCCCCCEEEEEECHHHCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHH
AAHAAQNSKEAG
HHHHHCCCCCCC
>Mature Secondary Structure 
AEQTLHPLSAGDNRGETQDSEGQSTQRSSVTEKRSLLSNIFPFMRARQASSLREDLADA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSSATSEDGAAFSPEEKAMLHNILRLREIRVEDVMIPRADVEAVEITTPLWEVLELFEKS
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEECHHHHHHHHHHHHC
GHSRMPVYAETLDDPRGMIHIRDVLNYITRQARQKARRRTTAKSAATEVAPKFDMSRIDL
CCCCCCCHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AKTIGELNLMRKVLFVPPSMMASGLMARMQASHIQMALVIDEYGGTDGLVSLEDIVEMVV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCEEHHHHHHHHH
GDIEDEHDDEEIMIAEDADGVFVVDARADLEELAARIGPGFAVGEHGEDVDTVGGLIFSV
HCCCCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHCCCCEECCCCCCHHHHHHHHHHH
LGRIPVRGEVVQAIPDYEFHVLEVDPRRVKKVRIVPLSAADRRRQQRAVVSARPEDHAAD
HCCCCCCCHHHHHCCCCCEEEEEECHHHCCEEEEEECCHHHHHHHHHHHHHCCCCHHHHH
AAHAAQNSKEAG
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA