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The map label for this gene is nccN [H]

Identifier: 225853545

GI number: 225853545

Start: 2060101

End: 2060715

Strand: Direct

Name: nccN [H]

Synonym: BMEA_A2178

Alternate gene names: 225853545

Gene position: 2060101-2060715 (Clockwise)

Preceding gene: 225853544

Following gene: 225853546

Centisome position: 96.91

GC content: 54.8

Gene sequence:

>615_bases
ATGAAGACATTGGGTGAACTGGGGCTGTATCAGCGCCGCCGCCGCTTTGCGATCGGTGGGGTGATTGTTCTTTTGGTCAT
CGCGCTTATCTTCGTGCGCTCGCAATCGACCGGCTCGCTGCACGAATATATCGAAGCCTTCGGCATCAGTCTCATTGTTG
CGGCCATTATCGGGCGCATGTGGTGCACGCTTTATATCGGCGGACGCAAGAGCGCGGAAATCGTGCAGAGCGGCCCCTAT
TCGGTGACGCGCAACCCGCTTTATGTCTTCAGCAGCATTGGTGCGGTGGGCATCGGCGCCCAGACCGGCAGCCTCATCGT
CGCGGCAGCTTTCGGCGTGTTGTGTTATCTCGCCTTTTCGATTGTCATCCGGACGGAGGAGAAATTCCTCAAACAGAATT
TCGGGCGACCTTACGAAGCCTATTGTGCCAAGGTGCCGCGTTTTTTTCCGAAGTTTTCGCTGTTTCACGACGACAAGGAA
CTGATCGTGCGGCCAGACCGGATTTACCGTACCTTTACGGACGGTCTGGTTTTCTTCGTGGCCTATCCGTTCTTTGAATT
CGTGGAATATCTGCAAAACAGCCATATCCTGCCGGTGCTTCTGCGGCTTTATTGA

Upstream 100 bases:

>100_bases
TTTCCTTGAAACCATGCCGTGAAAGAAACCATGTCTTGGAAAAGCCGCCTTTCGGGCGGTTTTTCTTTGCTCGAAACGAA
TATTCAAAGATGGGACAACC

Downstream 100 bases:

>100_bases
CGTTTTCAGCTCAATTCGGGCATTGCGTTTTGCGGCCATTGGGCCTATAAGGCCGCGTTCAAACCGCCCGGCAGGGCATG
CCGTGGCGGTTTCGTATGCT

Product: nickel-cobalt-cadmium resistance protein NccN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MKTLGELGLYQRRRRFAIGGVIVLLVIALIFVRSQSTGSLHEYIEAFGISLIVAAIIGRMWCTLYIGGRKSAEIVQSGPY
SVTRNPLYVFSSIGAVGIGAQTGSLIVAAAFGVLCYLAFSIVIRTEEKFLKQNFGRPYEAYCAKVPRFFPKFSLFHDDKE
LIVRPDRIYRTFTDGLVFFVAYPFFEFVEYLQNSHILPVLLRLY

Sequences:

>Translated_204_residues
MKTLGELGLYQRRRRFAIGGVIVLLVIALIFVRSQSTGSLHEYIEAFGISLIVAAIIGRMWCTLYIGGRKSAEIVQSGPY
SVTRNPLYVFSSIGAVGIGAQTGSLIVAAAFGVLCYLAFSIVIRTEEKFLKQNFGRPYEAYCAKVPRFFPKFSLFHDDKE
LIVRPDRIYRTFTDGLVFFVAYPFFEFVEYLQNSHILPVLLRLY
>Mature_204_residues
MKTLGELGLYQRRRRFAIGGVIVLLVIALIFVRSQSTGSLHEYIEAFGISLIVAAIIGRMWCTLYIGGRKSAEIVQSGPY
SVTRNPLYVFSSIGAVGIGAQTGSLIVAAAFGVLCYLAFSIVIRTEEKFLKQNFGRPYEAYCAKVPRFFPKFSLFHDDKE
LIVRPDRIYRTFTDGLVFFVAYPFFEFVEYLQNSHILPVLLRLY

Specific function: Component of the NCC cation-efflux system that confers resistance to nickel, cobalt and cadmium. Appears to be involved in metal specificity but affects only nickel resistance. May be involved in nickel transport [H]

COG id: COG2020

COG function: function code O; Putative protein-S-isoprenylcysteine methyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To A.eutrophus CzcN [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007269 [H]

Pfam domain/function: PF04140 ICMT [H]

EC number: NA

Molecular weight: Translated: 23075; Mature: 23075

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLGELGLYQRRRRFAIGGVIVLLVIALIFVRSQSTGSLHEYIEAFGISLIVAAIIGRM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
WCTLYIGGRKSAEIVQSGPYSVTRNPLYVFSSIGAVGIGAQTGSLIVAAAFGVLCYLAFS
HHHHEECCCCCHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IVIRTEEKFLKQNFGRPYEAYCAKVPRFFPKFSLFHDDKELIVRPDRIYRTFTDGLVFFV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHCCCCHHHEECHHHHHHHHHHHHHHHH
AYPFFEFVEYLQNSHILPVLLRLY
HHHHHHHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure
MKTLGELGLYQRRRRFAIGGVIVLLVIALIFVRSQSTGSLHEYIEAFGISLIVAAIIGRM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
WCTLYIGGRKSAEIVQSGPYSVTRNPLYVFSSIGAVGIGAQTGSLIVAAAFGVLCYLAFS
HHHHEECCCCCHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IVIRTEEKFLKQNFGRPYEAYCAKVPRFFPKFSLFHDDKELIVRPDRIYRTFTDGLVFFV
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHCCCCHHHEECHHHHHHHHHHHHHHHH
AYPFFEFVEYLQNSHILPVLLRLY
HHHHHHHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7961470 [H]