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The map label for this gene is infC

Identifier: 225853544

GI number: 225853544

Start: 2059568

End: 2059972

Strand: Direct

Name: infC

Synonym: BMEA_A2177

Alternate gene names: 225853544

Gene position: 2059568-2059972 (Clockwise)

Preceding gene: 225853532

Following gene: 225853545

Centisome position: 96.89

GC content: 54.57

Gene sequence:

>405_bases
ATGGCCATGGCGGAAGAGGCGGGTCTCGATCTTGTTGAGATCGTGCCGAACGCCGAACCGCCAGTTTGCAAGATCGTGGA
CCTTGGCAAGCTGAAATATCAAAATCAGAAAAAAGCCGCCGAAGCGCGCAAGAAGCAGAAGACGGTCGAGATCAAGGAAA
TCAAGATGCGGCCGAACATCGACACCCATGACTATGAGGTGAAGATGAAAGCAGCGCAGCGTTTCTTTGAGGAAGGCGAC
AAGGTCAAGGTCACCTTGCGTTTCCGTGGCCGTGAAATGGCGCACCAGGAACTGGGTATGAAGCTTCTGCAACGCGTCAA
GGAAGACACGGTTGAAATCGCCAAGGTGGAATCCGAGCCGAAGCTCGAAGGCCGCCAGATGATGATGGTGCTGGCACCTC
GCTGA

Upstream 100 bases:

>100_bases
GAAAGACGGACCGCGCTCCAACCGTGATATCCGGGTTCCCCGGGTTCAGCTTATTGACGCCGAAGGCCAGAACCATGGGG
ACGTTTCCATTCAGGAAGCC

Downstream 100 bases:

>100_bases
TTTTGCATCCGTTTTCGGGAAACGCCGTTTTCCTTGAAACCATGCCGTGAAAGAAACCATGTCTTGGAAAAGCCGCCTTT
CGGGCGGTTTTTCTTTGCTC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 133

Protein sequence:

>134_residues
MAMAEEAGLDLVEIVPNAEPPVCKIVDLGKLKYQNQKKAAEARKKQKTVEIKEIKMRPNIDTHDYEVKMKAAQRFFEEGD
KVKVTLRFRGREMAHQELGMKLLQRVKEDTVEIAKVESEPKLEGRQMMMVLAPR

Sequences:

>Translated_134_residues
MAMAEEAGLDLVEIVPNAEPPVCKIVDLGKLKYQNQKKAAEARKKQKTVEIKEIKMRPNIDTHDYEVKMKAAQRFFEEGD
KVKVTLRFRGREMAHQELGMKLLQRVKEDTVEIAKVESEPKLEGRQMMMVLAPR
>Mature_133_residues
AMAEEAGLDLVEIVPNAEPPVCKIVDLGKLKYQNQKKAAEARKKQKTVEIKEIKMRPNIDTHDYEVKMKAAQRFFEEGDK
VKVTLRFRGREMAHQELGMKLLQRVKEDTVEIAKVESEPKLEGRQMMMVLAPR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=132, Percent_Identity=63.6363636363636, Blast_Score=163, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_BRUAB (P0A3L0)

Other databases:

- EMBL:   AF196569
- EMBL:   AE017223
- RefSeq:   YP_222750.1
- ProteinModelPortal:   P0A3L0
- GeneID:   3340531
- GenomeReviews:   AE017223_GR
- KEGG:   bmb:BruAb1_2092
- HOGENOM:   HBG744268
- OMA:   FDRRAPV
- ProtClustDB:   PRK00028
- BioCyc:   BABO262698:BRUAB1_2092-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 15451; Mature: 15320

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMAEEAGLDLVEIVPNAEPPVCKIVDLGKLKYQNQKKAAEARKKQKTVEIKEIKMRPNI
CCCCCHHCCCEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCC
DTHDYEVKMKAAQRFFEEGDKVKVTLRFRGREMAHQELGMKLLQRVKEDTVEIAKVESEP
CCCCCEEHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KLEGRQMMMVLAPR
CCCCCEEEEEECCC
>Mature Secondary Structure 
AMAEEAGLDLVEIVPNAEPPVCKIVDLGKLKYQNQKKAAEARKKQKTVEIKEIKMRPNI
CCCCHHCCCEEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCC
DTHDYEVKMKAAQRFFEEGDKVKVTLRFRGREMAHQELGMKLLQRVKEDTVEIAKVESEP
CCCCCEEHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KLEGRQMMMVLAPR
CCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA