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The map label for this gene is coaA [H]

Identifier: 225853518

GI number: 225853518

Start: 2027368

End: 2028336

Strand: Direct

Name: coaA [H]

Synonym: BMEA_A2149

Alternate gene names: 225853518

Gene position: 2027368-2028336 (Clockwise)

Preceding gene: 225853517

Following gene: 225853520

Centisome position: 95.37

GC content: 57.59

Gene sequence:

>969_bases
ATGTGGGAAAAAGTCGATCAGCTCACCCCGTCCCGGTATTCGCCCTACCGCTTCTTTTCGGCGCAGGAATGGGCAGCCTT
CCGGGCCGATACACCGCTCACCCTCACCTATGAAGAGGTCAAGCGGCTGCGCTCGCTGGGCGACCCGATTGATCTGGATG
AAGTGCGGCGCATCTATCTGTCGCTCTCGCGGCTTCTTTATGCGCATGTGGAGGCAAGCCAGCTTCTGTTTCGCCAGCGC
CAGCAATTCCTCAACATGGAGGAATCCTACAAGACCCCCTTCATCATCGGTGTGGCCGGGTCCGTGGCGGTGGGCAAGTC
CACCATGGCACGTATCCTCAAGGAGCTTCTGGCCCGCTGGCCGTCAAGCCCCAAGGTCGACCTCGTGACGACCGACGGTT
TTCTCTATCCCAACGCGGTCCTGCGCGAGCAGAACATGATGGAGCGAAAGGGCTTTCCCGAAAGCTACGATATTGGCGCG
GTCCTGCGCTTCCTGTCGGCGATCAAGGCGGGCATGAGCCGTGTGCGCGCGCCGCTCTATTCGCATTTGAGCTATGATGT
GCTCCCCGGCGAGTACCAGATCGTCGACAAGCCCGATATTCTGATTTTTGAAGGCATTAACGTGTTGCAGGTGCGCGATC
TGCCGGAAGACGGCAAGATGGTGCCTTTCGTATCGGATTTCTTCGATTTCTCGATCTATATCGATGCCGATCCGCGCCTG
ATCCATAAATGGTATATCGACCGCTTCATGCGCCTGCGTGAAACGGCGTTTCGCGACCCGCAATCCTTCTTCCATCGCTA
TTCGCAGCTTTCGCAGGAGGCGGCCCGCTCCATCGCCGAGGGCCTCTGGCAGAATATCAACCTGAAGAACCTGAATGAGA
ATATTCTGCCCACCCGCCCCCGCGCCGATCTCATCTTGCGAAAAGGCAGCGATCATCTGATTGAGGAAGTGGCTCTCAGG
AAAATCTGA

Upstream 100 bases:

>100_bases
TGGCGCTGGAGGATGTGCTTCAGGAACTTCAGCGCCGCACCGCCCAGACCGGCCTTGCGGAAAAGGCCAGCCGCCCGAAG
GGCTGAAAGGCAAATCGTCC

Downstream 100 bases:

>100_bases
CGCGAGCATTCTTTCCCCATGACCGGATGCAAAACCGGTTCCCGCTTCCGGGTCATTACAGCCTAATCAAAAGAAACCTT
GCCGCGTCCTTTTTTGATCT

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MWEKVDQLTPSRYSPYRFFSAQEWAAFRADTPLTLTYEEVKRLRSLGDPIDLDEVRRIYLSLSRLLYAHVEASQLLFRQR
QQFLNMEESYKTPFIIGVAGSVAVGKSTMARILKELLARWPSSPKVDLVTTDGFLYPNAVLREQNMMERKGFPESYDIGA
VLRFLSAIKAGMSRVRAPLYSHLSYDVLPGEYQIVDKPDILIFEGINVLQVRDLPEDGKMVPFVSDFFDFSIYIDADPRL
IHKWYIDRFMRLRETAFRDPQSFFHRYSQLSQEAARSIAEGLWQNINLKNLNENILPTRPRADLILRKGSDHLIEEVALR
KI

Sequences:

>Translated_322_residues
MWEKVDQLTPSRYSPYRFFSAQEWAAFRADTPLTLTYEEVKRLRSLGDPIDLDEVRRIYLSLSRLLYAHVEASQLLFRQR
QQFLNMEESYKTPFIIGVAGSVAVGKSTMARILKELLARWPSSPKVDLVTTDGFLYPNAVLREQNMMERKGFPESYDIGA
VLRFLSAIKAGMSRVRAPLYSHLSYDVLPGEYQIVDKPDILIFEGINVLQVRDLPEDGKMVPFVSDFFDFSIYIDADPRL
IHKWYIDRFMRLRETAFRDPQSFFHRYSQLSQEAARSIAEGLWQNINLKNLNENILPTRPRADLILRKGSDHLIEEVALR
KI
>Mature_322_residues
MWEKVDQLTPSRYSPYRFFSAQEWAAFRADTPLTLTYEEVKRLRSLGDPIDLDEVRRIYLSLSRLLYAHVEASQLLFRQR
QQFLNMEESYKTPFIIGVAGSVAVGKSTMARILKELLARWPSSPKVDLVTTDGFLYPNAVLREQNMMERKGFPESYDIGA
VLRFLSAIKAGMSRVRAPLYSHLSYDVLPGEYQIVDKPDILIFEGINVLQVRDLPEDGKMVPFVSDFFDFSIYIDADPRL
IHKWYIDRFMRLRETAFRDPQSFFHRYSQLSQEAARSIAEGLWQNINLKNLNENILPTRPRADLILRKGSDHLIEEVALR
KI

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=311, Percent_Identity=51.7684887459807, Blast_Score=317, Evalue=5e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 37478; Mature: 37478

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWEKVDQLTPSRYSPYRFFSAQEWAAFRADTPLTLTYEEVKRLRSLGDPIDLDEVRRIYL
CCCCHHHCCCCCCCCEEECCCHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHH
SLSRLLYAHVEASQLLFRQRQQFLNMEESYKTPFIIGVAGSVAVGKSTMARILKELLARW
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHC
PSSPKVDLVTTDGFLYPNAVLREQNMMERKGFPESYDIGAVLRFLSAIKAGMSRVRAPLY
CCCCCEEEEECCCEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SHLSYDVLPGEYQIVDKPDILIFEGINVLQVRDLPEDGKMVPFVSDFFDFSIYIDADPRL
HHCCCCCCCCCEEEECCCCEEEECCCCEEEEECCCCCCCCCCCHHHCCCEEEEECCCHHH
IHKWYIDRFMRLRETAFRDPQSFFHRYSQLSQEAARSIAEGLWQNINLKNLNENILPTRP
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
RADLILRKGSDHLIEEVALRKI
CHHEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure
MWEKVDQLTPSRYSPYRFFSAQEWAAFRADTPLTLTYEEVKRLRSLGDPIDLDEVRRIYL
CCCCHHHCCCCCCCCEEECCCHHHHHHCCCCCCEEEHHHHHHHHHCCCCCCHHHHHHHHH
SLSRLLYAHVEASQLLFRQRQQFLNMEESYKTPFIIGVAGSVAVGKSTMARILKELLARW
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHC
PSSPKVDLVTTDGFLYPNAVLREQNMMERKGFPESYDIGAVLRFLSAIKAGMSRVRAPLY
CCCCCEEEEECCCEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
SHLSYDVLPGEYQIVDKPDILIFEGINVLQVRDLPEDGKMVPFVSDFFDFSIYIDADPRL
HHCCCCCCCCCEEEECCCCEEEECCCCEEEEECCCCCCCCCCCHHHCCCEEEEECCCHHH
IHKWYIDRFMRLRETAFRDPQSFFHRYSQLSQEAARSIAEGLWQNINLKNLNENILPTRP
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
RADLILRKGSDHLIEEVALRKI
CHHEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA