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The map label for this gene is yjiA [H]

Identifier: 225853469

GI number: 225853469

Start: 1977687

End: 1978859

Strand: Reverse

Name: yjiA [H]

Synonym: BMEA_A2095

Alternate gene names: 225853469

Gene position: 1978859-1977687 (Counterclockwise)

Preceding gene: 225853470

Following gene: 225853463

Centisome position: 93.09

GC content: 59.59

Gene sequence:

>1173_bases
ATGCCTGATCCCATTCCCGTTTCCGTGCTGACCGGCTTTCTTGGCTCCGGCAAGACGACGCTGCTCAACCGGCTTTTGAA
AGATCCGGCGCTCAGCGATACAGCAGTCATTATCAACGAGTTCGGCGAGGTGAGCATTGACCATCTGCTGGTCGAGCAGG
CGAGCGAGGGCGTGATCGAGCTGGCTGACGGGTGTCTGTGCTGCACAGTGCGCGGTGAACTGGTCGATACGCTGGCCGAT
CTCATCGACCGGTTGCAGACCGGCCGCATCAAGGCGCTGAAGCGCGTCATCATCGAAACCACGGGGCTTGCCGATCCGGC
CCCGGTGCTGCATTCGATCATGGGTCATCCTCTTCTCACGCAGGTTTTCCGGCTTGATGGCGTGCTGGCTACCGTGGATG
CGGTGAACGGCATGGCAACGCTCGACAATCATGAGGAAGCCGTCAAACAGGCAGCCATGGCCGACCGCATCATCCTCACC
AAGACCGATCTGCCGGAAGCACAGGCTGGCTTGCCGGCATTGAAGGCACGGTTGCGCACGCTTAACCCCGGAGCCGATAT
TCTGGAAGCGGGGGAAGAGCGCACAGGCTATGCCGCGCTTTTTGAATGCGGGCTTTATAACCCGCAGACGAAATCGGCGG
ATGTGCGGCGCTGGCTTAAGGCCGAAGCCTATGAGGACGAGCATCATGGCCATGGCCATGTGTGCGGGCCGGATTGCGGT
CACGACCATCATCACCACGATCACCATCACGATCATCATAACGATCAGGGCTATGCGCATCATCATCATCATGACGATGC
GATCCGTTCGTTTTCACTGTGCCATGATGCGCCGATCCCGGTTTCGACCTTCGAGATGTTTCTCGATCTTCTGCGTTCGA
CCCATGGTGAAAAGCTCTTGCGCATGAAGGGTATCGTGCAGATTGCCGAAGACCCGGACCGCCCGGTCGTCATCCATGGT
GTGCAGAAGATTTTCCATCCGCCCGCGCGCCTGCCGCAATGGCCGCAAGGCAAGCGCGAAACGCTTCTGGTCCTGATTGT
GAAGGACTTGCCGGAGGCCTATGTGCGGGAACTTTTCGATGCCTTTCTGGGCCGGCCCGGCCTCGACAGGCCCGACCGCG
CAGCCATGACTGAAAATCCGCTGGCCATTCCGGGGTTCTCACCCCGCCGGTAA

Upstream 100 bases:

>100_bases
TCGATCAACCGGCCCGGCCAGCCCGGCATTTCGCGGGTTCCGGTGCCAATGCCGCGTCCGCAGCGCGCGCCAGGCGTAAA
GACAACGGCCATCAACTGAT

Downstream 100 bases:

>100_bases
GCCGGTAAGTATTTGCTTTATTTCCTGCGAATGAGAAAGCGGTGAAGCGTGCCTTCCCGCTCCTGCGCAATCAGGGAGTG
GCCTTCCTGTACGCAGAAAT

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MPDPIPVSVLTGFLGSGKTTLLNRLLKDPALSDTAVIINEFGEVSIDHLLVEQASEGVIELADGCLCCTVRGELVDTLAD
LIDRLQTGRIKALKRVIIETTGLADPAPVLHSIMGHPLLTQVFRLDGVLATVDAVNGMATLDNHEEAVKQAAMADRIILT
KTDLPEAQAGLPALKARLRTLNPGADILEAGEERTGYAALFECGLYNPQTKSADVRRWLKAEAYEDEHHGHGHVCGPDCG
HDHHHHDHHHDHHNDQGYAHHHHHDDAIRSFSLCHDAPIPVSTFEMFLDLLRSTHGEKLLRMKGIVQIAEDPDRPVVIHG
VQKIFHPPARLPQWPQGKRETLLVLIVKDLPEAYVRELFDAFLGRPGLDRPDRAAMTENPLAIPGFSPRR

Sequences:

>Translated_390_residues
MPDPIPVSVLTGFLGSGKTTLLNRLLKDPALSDTAVIINEFGEVSIDHLLVEQASEGVIELADGCLCCTVRGELVDTLAD
LIDRLQTGRIKALKRVIIETTGLADPAPVLHSIMGHPLLTQVFRLDGVLATVDAVNGMATLDNHEEAVKQAAMADRIILT
KTDLPEAQAGLPALKARLRTLNPGADILEAGEERTGYAALFECGLYNPQTKSADVRRWLKAEAYEDEHHGHGHVCGPDCG
HDHHHHDHHHDHHNDQGYAHHHHHDDAIRSFSLCHDAPIPVSTFEMFLDLLRSTHGEKLLRMKGIVQIAEDPDRPVVIHG
VQKIFHPPARLPQWPQGKRETLLVLIVKDLPEAYVRELFDAFLGRPGLDRPDRAAMTENPLAIPGFSPRR
>Mature_389_residues
PDPIPVSVLTGFLGSGKTTLLNRLLKDPALSDTAVIINEFGEVSIDHLLVEQASEGVIELADGCLCCTVRGELVDTLADL
IDRLQTGRIKALKRVIIETTGLADPAPVLHSIMGHPLLTQVFRLDGVLATVDAVNGMATLDNHEEAVKQAAMADRIILTK
TDLPEAQAGLPALKARLRTLNPGADILEAGEERTGYAALFECGLYNPQTKSADVRRWLKAEAYEDEHHGHGHVCGPDCGH
DHHHHDHHHDHHNDQGYAHHHHHDDAIRSFSLCHDAPIPVSTFEMFLDLLRSTHGEKLLRMKGIVQIAEDPDRPVVIHGV
QKIFHPPARLPQWPQGKRETLLVLIVKDLPEAYVRELFDAFLGRPGLDRPDRAAMTENPLAIPGFSPRR

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=378, Percent_Identity=27.7777777777778, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI126722884, Length=378, Percent_Identity=27.2486772486773, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI148727351, Length=378, Percent_Identity=27.5132275132275, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI146231952, Length=378, Percent_Identity=27.7777777777778, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI223941779, Length=198, Percent_Identity=37.3737373737374, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI223941776, Length=368, Percent_Identity=26.3586956521739, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI119120938, Length=139, Percent_Identity=38.1294964028777, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI87082430, Length=358, Percent_Identity=32.4022346368715, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788499, Length=173, Percent_Identity=34.1040462427746, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324356, Length=204, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 43009; Mature: 42877

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPIPVSVLTGFLGSGKTTLLNRLLKDPALSDTAVIINEFGEVSIDHLLVEQASEGVIE
CCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCHHH
LADGCLCCTVRGELVDTLADLIDRLQTGRIKALKRVIIETTGLADPAPVLHSIMGHPLLT
HHCCEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHH
QVFRLDGVLATVDAVNGMATLDNHEEAVKQAAMADRIILTKTDLPEAQAGLPALKARLRT
HHHHHCCHHHHHHHHCCCHHCCCHHHHHHHHHHHCCEEEEECCCCHHHCCCHHHHHHHHH
LNPGADILEAGEERTGYAALFECGLYNPQTKSADVRRWLKAEAYEDEHHGHGHVCGPDCG
CCCCHHHHHCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
HDHHHHDHHHDHHNDQGYAHHHHHDDAIRSFSLCHDAPIPVSTFEMFLDLLRSTHGEKLL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHH
RMKGIVQIAEDPDRPVVIHGVQKIFHPPARLPQWPQGKRETLLVLIVKDLPEAYVRELFD
HHHHHHHHCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHCCHHHHHHHHH
AFLGRPGLDRPDRAAMTENPLAIPGFSPRR
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PDPIPVSVLTGFLGSGKTTLLNRLLKDPALSDTAVIINEFGEVSIDHLLVEQASEGVIE
CCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCHHH
LADGCLCCTVRGELVDTLADLIDRLQTGRIKALKRVIIETTGLADPAPVLHSIMGHPLLT
HHCCEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHH
QVFRLDGVLATVDAVNGMATLDNHEEAVKQAAMADRIILTKTDLPEAQAGLPALKARLRT
HHHHHCCHHHHHHHHCCCHHCCCHHHHHHHHHHHCCEEEEECCCCHHHCCCHHHHHHHHH
LNPGADILEAGEERTGYAALFECGLYNPQTKSADVRRWLKAEAYEDEHHGHGHVCGPDCG
CCCCHHHHHCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
HDHHHHDHHHDHHNDQGYAHHHHHDDAIRSFSLCHDAPIPVSTFEMFLDLLRSTHGEKLL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHH
RMKGIVQIAEDPDRPVVIHGVQKIFHPPARLPQWPQGKRETLLVLIVKDLPEAYVRELFD
HHHHHHHHCCCCCCCEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHCCHHHHHHHHH
AFLGRPGLDRPDRAAMTENPLAIPGFSPRR
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]