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The map label for this gene is 225853337

Identifier: 225853337

GI number: 225853337

Start: 1853398

End: 1853769

Strand: Reverse

Name: 225853337

Synonym: BMEA_A1953

Alternate gene names: NA

Gene position: 1853769-1853398 (Counterclockwise)

Preceding gene: 225853338

Following gene: 225853335

Centisome position: 87.21

GC content: 55.91

Gene sequence:

>372_bases
ATGCTCGATCATATCGGTTTCAATATTGCGGATATGAAAAAGTCGCGCGCATTTTATGATGCGGCGCTGTCTCCGCTTGG
TATCGGCCATGCCATGGAATTCGGAGATTGGGTTGGCTACGGGCGAAATGGCAAGCCGGAATTCTGGATCGGAGCACAGA
AAGGCGCGAAACTGGAAGGCGTGTTGCATGTGGCCTTTTCAGCCGGGACGCGTTCGGAAGTGGACCGCTTTTACGAAGCC
GCAATCGCTGCCGGGGGCAGGGATAATGGCAAGCCGGGCCTGAGGCCCCACTACCACCCGGATTACTATGCGGCTTTCGT
GCTGGACCCGGATGGCCACAATATAGAAGTCGTCTGCCATCTGCCGGAATAA

Upstream 100 bases:

>100_bases
CAACCTTCCCCTTTTGCTATGTTCGGTCCGCGTTGTAGACTTGATCTCTTGAAGTGTTTTCATATTTTTGCAGGAAACAA
TTATATGGGAGGGACCGAAC

Downstream 100 bases:

>100_bases
AGCACTTCCAGCGATTCTGTTAAAACAGGAACCGCGTAGGCGTTTCACACTTTTGCTGGAAATGCTCTAGGGACGAGGCC
TGGACTCAGATAGGCTCGCC

Product: glyoxalase/bleomycin resistance protein/dioxygenase

Products: glutathione; methylglyoxal

Alternate protein names: Glyoxalase Family Protein; Lactoylglutathione Lyase; Lactoylglutathione Lyase Protein; Glyoxalase; Glyoxalase/Bleomycin Resistance Protein; Glyoxalase/Dioxygenase; Dioxygenase; Lactoylglutathione Lyase-Like Lyase; Exported Glyoxalase; Asparaginyl-TRNA Synthetase; Glyoxylase; Glyoxalase/Bleomycin Resistance/Dioxygenase; Glyoxalase-Family Protein; Glyoxalase Family Protein Family Protein; Lactoylgluthathione Lyase; Dioxygenase-Family Protein; Glyoxylase Protein

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MLDHIGFNIADMKKSRAFYDAALSPLGIGHAMEFGDWVGYGRNGKPEFWIGAQKGAKLEGVLHVAFSAGTRSEVDRFYEA
AIAAGGRDNGKPGLRPHYHPDYYAAFVLDPDGHNIEVVCHLPE

Sequences:

>Translated_123_residues
MLDHIGFNIADMKKSRAFYDAALSPLGIGHAMEFGDWVGYGRNGKPEFWIGAQKGAKLEGVLHVAFSAGTRSEVDRFYEA
AIAAGGRDNGKPGLRPHYHPDYYAAFVLDPDGHNIEVVCHLPE
>Mature_123_residues
MLDHIGFNIADMKKSRAFYDAALSPLGIGHAMEFGDWVGYGRNGKPEFWIGAQKGAKLEGVLHVAFSAGTRSEVDRFYEA
AIAAGGRDNGKPGLRPHYHPDYYAAFVLDPDGHNIEVVCHLPE

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.4.1.5

Molecular weight: Translated: 13473; Mature: 13473

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDHIGFNIADMKKSRAFYDAALSPLGIGHAMEFGDWVGYGRNGKPEFWIGAQKGAKLEG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCEEEECCCCCCEEE
VLHVAFSAGTRSEVDRFYEAAIAAGGRDNGKPGLRPHYHPDYYAAFVLDPDGHNIEVVCH
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEE
LPE
CCC
>Mature Secondary Structure
MLDHIGFNIADMKKSRAFYDAALSPLGIGHAMEFGDWVGYGRNGKPEFWIGAQKGAKLEG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCEEEECCCCCCEEE
VLHVAFSAGTRSEVDRFYEAAIAAGGRDNGKPGLRPHYHPDYYAAFVLDPDGHNIEVVCH
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEEEE
LPE
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA