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The map label for this gene is gpsA

Identifier: 225853326

GI number: 225853326

Start: 1841816

End: 1842796

Strand: Direct

Name: gpsA

Synonym: BMEA_A1942

Alternate gene names: 225853326

Gene position: 1841816-1842796 (Clockwise)

Preceding gene: 225853325

Following gene: 225853327

Centisome position: 86.65

GC content: 62.49

Gene sequence:

>981_bases
ATGAGCACGAAAATTGCCGTTCTGGGTGGTGGCGCATGGGGCACGGCGCTTGCCGCCATGGCTGCAAAGGGCGGCCATGA
AAGCTGGCTTTACGCCCGCGATGCCGAAACAGTCGTGGCAATAAACAAGGATCGTCGCAATCCGCGCTATCTGGGTGACA
TCACCTTGGCCGACGGCATTCGCGCCAGCACCGATGCGGCAGCGGTTGTGACTGGCGCCGATGCGGTTCTTGCTGTCATC
CCGGCGCAAGCCATGCGAAACGGCCTGTCCGAACTTGGAACGCTCATCCCGCAGGCTTCACCCATCGTTCTTTGCGCAAA
AGGGATCGAGCAGAATACCGGGCGGCTCATGTCGGAAGTGGTGGCGGAAATTTTGCCGGACCATCGCATTGCAGCCCTTT
CCGGCCCAAGCTTCGCCAGCGACGTGGCGCGCGGCCTGCCGACAGCCGTGACGGTTGCCTGCGAGGATGCAAACACCGCA
GACCGGCTTGCGGCCCTTCTTTCCGGCCCGGCCTTTCGCTGCTATTCCACCACCGATCTCAAGGGGGTCGAAACCGGCGG
CGCATTGAAAAACGTTCTGGCCATTGCGGCAGGCGCCGCCATCGGGCGCGGCTATGGGGCAAGCGCGCAAGCTGCCCTTG
TCACGCGTGGCTTTGCCGAACTGCGCCGCATCGGACAGGCGATGAGCGCAAGGCCCGAAACCATTATGGGGCTTTCCGGC
CTTGGCGACCTGATGCTCACCTGCTCCTCGTCGCAGTCGCGCAATTATTCCTATGGATTGGCGCTGGGACGCGGCGAAGA
CCTGACCAGCCGGCCGCTGGCCGAAGGCGTGGCCACCGCGCCGATTGCCGCAGAGCTTTGCCGCAAGCACAATATTTCCG
CGCCCATCATCGATGCCGTGGGGGCGCTGCTTGACGGAAAAATCACCATCGATGAAGCAGTCACCGCTCTTCTCAACCGA
CCACTCAAGACCGAGGATTAA

Upstream 100 bases:

>100_bases
CCCAAGCGCCTGATTCGCTTGACATCGCCCCGCGCTCGCGCTGGCCGCTCGACGAAAAATCCGCGCCGGTCTTCGGCACG
GGACGGCGGGGAGCAAAGGC

Downstream 100 bases:

>100_bases
AATGCTGTTTGCCCTCCTGTGCAATGACAAGCCCGACCATCTGCAAGTGCGTCTCGATACCCGCCCGGCGCATCTGGACT
ATCTGAAGAGCCTCGGCGAC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSTKIAVLGGGAWGTALAAMAAKGGHESWLYARDAETVVAINKDRRNPRYLGDITLADGIRASTDAAAVVTGADAVLAVI
PAQAMRNGLSELGTLIPQASPIVLCAKGIEQNTGRLMSEVVAEILPDHRIAALSGPSFASDVARGLPTAVTVACEDANTA
DRLAALLSGPAFRCYSTTDLKGVETGGALKNVLAIAAGAAIGRGYGASAQAALVTRGFAELRRIGQAMSARPETIMGLSG
LGDLMLTCSSSQSRNYSYGLALGRGEDLTSRPLAEGVATAPIAAELCRKHNISAPIIDAVGALLDGKITIDEAVTALLNR
PLKTED

Sequences:

>Translated_326_residues
MSTKIAVLGGGAWGTALAAMAAKGGHESWLYARDAETVVAINKDRRNPRYLGDITLADGIRASTDAAAVVTGADAVLAVI
PAQAMRNGLSELGTLIPQASPIVLCAKGIEQNTGRLMSEVVAEILPDHRIAALSGPSFASDVARGLPTAVTVACEDANTA
DRLAALLSGPAFRCYSTTDLKGVETGGALKNVLAIAAGAAIGRGYGASAQAALVTRGFAELRRIGQAMSARPETIMGLSG
LGDLMLTCSSSQSRNYSYGLALGRGEDLTSRPLAEGVATAPIAAELCRKHNISAPIIDAVGALLDGKITIDEAVTALLNR
PLKTED
>Mature_325_residues
STKIAVLGGGAWGTALAAMAAKGGHESWLYARDAETVVAINKDRRNPRYLGDITLADGIRASTDAAAVVTGADAVLAVIP
AQAMRNGLSELGTLIPQASPIVLCAKGIEQNTGRLMSEVVAEILPDHRIAALSGPSFASDVARGLPTAVTVACEDANTAD
RLAALLSGPAFRCYSTTDLKGVETGGALKNVLAIAAGAAIGRGYGASAQAALVTRGFAELRRIGQAMSARPETIMGLSGL
GDLMLTCSSSQSRNYSYGLALGRGEDLTSRPLAEGVATAPIAAELCRKHNISAPIIDAVGALLDGKITIDEAVTALLNRP
LKTED

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=282, Percent_Identity=29.0780141843972, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI24307999, Length=278, Percent_Identity=26.2589928057554, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1790037, Length=328, Percent_Identity=39.3292682926829, Blast_Score=231, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI17507425, Length=352, Percent_Identity=26.1363636363636, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI32564399, Length=345, Percent_Identity=26.9565217391304, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193210136, Length=354, Percent_Identity=26.5536723163842, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI32564403, Length=354, Percent_Identity=26.5536723163842, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI193210134, Length=342, Percent_Identity=24.5614035087719, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6324513, Length=274, Percent_Identity=30.6569343065693, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320181, Length=273, Percent_Identity=30.4029304029304, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136204, Length=350, Percent_Identity=24.8571428571429, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17136200, Length=350, Percent_Identity=24.8571428571429, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17136202, Length=355, Percent_Identity=24.5070422535211, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI22026922, Length=360, Percent_Identity=23.3333333333333, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362270, Length=339, Percent_Identity=24.4837758112094, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI45551945, Length=234, Percent_Identity=26.4957264957265, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_BRUA1 (B2S844)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935727.1
- ProteinModelPortal:   B2S844
- SMR:   B2S844
- GeneID:   6326871
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I17710
- HOGENOM:   HBG586392
- OMA:   AKGIEHG
- ProtClustDB:   PRK00094
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 33378; Mature: 33246

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 190-190 BINDING 107-107 BINDING 107-107 BINDING 139-139 BINDING 254-254 BINDING 275-275

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKIAVLGGGAWGTALAAMAAKGGHESWLYARDAETVVAINKDRRNPRYLGDITLADGI
CCCEEEEEECCHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCCCEEEEEEECCCC
RASTDAAAVVTGADAVLAVIPAQAMRNGLSELGTLIPQASPIVLCAKGIEQNTGRLMSEV
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHH
VAEILPDHRIAALSGPSFASDVARGLPTAVTVACEDANTADRLAALLSGPAFRCYSTTDL
HHHHCCCCEEEEECCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCCC
KGVETGGALKNVLAIAAGAAIGRGYGASAQAALVTRGFAELRRIGQAMSARPETIMGLSG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCC
LGDLMLTCSSSQSRNYSYGLALGRGEDLTSRPLAEGVATAPIAAELCRKHNISAPIIDAV
CCCEEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCHHHHHH
GALLDGKITIDEAVTALLNRPLKTED
HHHHCCCEEHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
STKIAVLGGGAWGTALAAMAAKGGHESWLYARDAETVVAINKDRRNPRYLGDITLADGI
CCEEEEEECCHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCCCEEEEEEECCCC
RASTDAAAVVTGADAVLAVIPAQAMRNGLSELGTLIPQASPIVLCAKGIEQNTGRLMSEV
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHH
VAEILPDHRIAALSGPSFASDVARGLPTAVTVACEDANTADRLAALLSGPAFRCYSTTDL
HHHHCCCCEEEEECCCCHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCEEEECCCCC
KGVETGGALKNVLAIAAGAAIGRGYGASAQAALVTRGFAELRRIGQAMSARPETIMGLSG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCC
LGDLMLTCSSSQSRNYSYGLALGRGEDLTSRPLAEGVATAPIAAELCRKHNISAPIIDAV
CCCEEEEECCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCHHHHHH
GALLDGKITIDEAVTALLNRPLKTED
HHHHCCCEEHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA