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The map label for this gene is gcp [H]

Identifier: 225853325

GI number: 225853325

Start: 1840740

End: 1841819

Strand: Direct

Name: gcp [H]

Synonym: BMEA_A1941

Alternate gene names: 225853325

Gene position: 1840740-1841819 (Clockwise)

Preceding gene: 225853319

Following gene: 225853326

Centisome position: 86.59

GC content: 63.61

Gene sequence:

>1080_bases
ATGCGCGTTCTTGGAATAGAAACAAGTTGCGACGAAACAGCCGCCGCAATCGTCGAGCGTGACGATATGGGCGAAGGGCG
GATTTTGTCCAATGTGGTTCTGAGCCAGATTGCCGAGCACGAGCCCTATGGCGGCGTGGTGCCGGAGATCGCCGCCCGCG
CCCATGTCGAGGCATTGGACAGGCTGGTGGACCGTGCCCTGAACGACGCGGGCCTGAAACTGTACGAGGTGGATGCAGTG
GCCGCTACGGCTGGCCCCGGCCTCATCGGCGGGCTGATCGTCGGGCTGATGACGGCAAAGGCGCTCGCCATGGCTGCACA
AAAGCCCTTCTATGCCGTCAACCATCTGGAAGGCCACGCGCTGACGGCGCGGCTGACCGACGGCCTGCCATTTCCCTATC
TGCTGCTTCTCGTTTCCGGTGGCCACACGCAGATGGTGCTTGTGCGCGGCATCGGCGATTATGAGCGCCTCGGCACCACC
ATCGACGATGCGCTGGGCGAAGCCTTCGACAAGACCGCAAAGCTTCTCGGCCTGCCTTATCCCGGTGGCCCGGCTGTCGA
GCGCATGGCGCTACAGGGCGACCAGAAGCGTTTTGCCCTGCCGCGCCCGCTGAAAGGCGAAGCACGGCTGGATTTTTCCT
TCTCCGGCCTTAAAACCGCCGTCCGCCAGACCGCAACCGAATTGGTGCCTCTCACCGATCAGGACGTCACCGATATATGC
GCCTCGTTTCAGGCTGCTGTCGCCGATACGCTTTCCGACCGTGTGGGCCGCTCGCTGGAGCGTTTCAAGACGGAATTCCC
GGATTGCGCCACGCCCTCCCTGGTGGTTGCAGGCGGGGTTGCAGCCAACAAGACCCTGCGTGCCGCACTGGAAAACCTCT
GCACCCGGCATGGCTTTGCCTTTATCGCTCCGCCGCTTAATCTTTGCACCGACAATGCAGCGATGATCGCATGGGCGGGG
GCTGAGCGCGCCGCGACCCAAGCGCCTGATTCGCTTGACATCGCCCCGCGCTCGCGCTGGCCGCTCGACGAAAAATCCGC
GCCGGTCTTCGGCACGGGACGGCGGGGAGCAAAGGCATGA

Upstream 100 bases:

>100_bases
CCGGGTTTCATCATTCGTTTTCATGCATGTCCAAAGGCAAAACCGGTTTCCACTTTTGCTGAACATGCGCCAATATGAGC
CAGGCAGGGTCTAACCGCAA

Downstream 100 bases:

>100_bases
GCACGAAAATTGCCGTTCTGGGTGGTGGCGCATGGGGCACGGCGCTTGCCGCCATGGCTGCAAAGGGCGGCCATGAAAGC
TGGCTTTACGCCCGCGATGC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRVLGIETSCDETAAAIVERDDMGEGRILSNVVLSQIAEHEPYGGVVPEIAARAHVEALDRLVDRALNDAGLKLYEVDAV
AATAGPGLIGGLIVGLMTAKALAMAAQKPFYAVNHLEGHALTARLTDGLPFPYLLLLVSGGHTQMVLVRGIGDYERLGTT
IDDALGEAFDKTAKLLGLPYPGGPAVERMALQGDQKRFALPRPLKGEARLDFSFSGLKTAVRQTATELVPLTDQDVTDIC
ASFQAAVADTLSDRVGRSLERFKTEFPDCATPSLVVAGGVAANKTLRAALENLCTRHGFAFIAPPLNLCTDNAAMIAWAG
AERAATQAPDSLDIAPRSRWPLDEKSAPVFGTGRRGAKA

Sequences:

>Translated_359_residues
MRVLGIETSCDETAAAIVERDDMGEGRILSNVVLSQIAEHEPYGGVVPEIAARAHVEALDRLVDRALNDAGLKLYEVDAV
AATAGPGLIGGLIVGLMTAKALAMAAQKPFYAVNHLEGHALTARLTDGLPFPYLLLLVSGGHTQMVLVRGIGDYERLGTT
IDDALGEAFDKTAKLLGLPYPGGPAVERMALQGDQKRFALPRPLKGEARLDFSFSGLKTAVRQTATELVPLTDQDVTDIC
ASFQAAVADTLSDRVGRSLERFKTEFPDCATPSLVVAGGVAANKTLRAALENLCTRHGFAFIAPPLNLCTDNAAMIAWAG
AERAATQAPDSLDIAPRSRWPLDEKSAPVFGTGRRGAKA
>Mature_359_residues
MRVLGIETSCDETAAAIVERDDMGEGRILSNVVLSQIAEHEPYGGVVPEIAARAHVEALDRLVDRALNDAGLKLYEVDAV
AATAGPGLIGGLIVGLMTAKALAMAAQKPFYAVNHLEGHALTARLTDGLPFPYLLLLVSGGHTQMVLVRGIGDYERLGTT
IDDALGEAFDKTAKLLGLPYPGGPAVERMALQGDQKRFALPRPLKGEARLDFSFSGLKTAVRQTATELVPLTDQDVTDIC
ASFQAAVADTLSDRVGRSLERFKTEFPDCATPSLVVAGGVAANKTLRAALENLCTRHGFAFIAPPLNLCTDNAAMIAWAG
AERAATQAPDSLDIAPRSRWPLDEKSAPVFGTGRRGAKA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=337, Percent_Identity=38.5756676557863, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI8923380, Length=347, Percent_Identity=31.700288184438, Blast_Score=140, Evalue=1e-33,
Organism=Escherichia coli, GI1789445, Length=350, Percent_Identity=51.1428571428571, Blast_Score=302, Evalue=3e-83,
Organism=Caenorhabditis elegans, GI17557464, Length=335, Percent_Identity=34.0298507462687, Blast_Score=164, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71995670, Length=323, Percent_Identity=32.8173374613003, Blast_Score=137, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6320099, Length=371, Percent_Identity=35.8490566037736, Blast_Score=186, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6322891, Length=349, Percent_Identity=26.3610315186246, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI20129063, Length=362, Percent_Identity=38.121546961326, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI21357207, Length=342, Percent_Identity=31.2865497076023, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37983; Mature: 37983

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIETSCDETAAAIVERDDMGEGRILSNVVLSQIAEHEPYGGVVPEIAARAHVEALD
CEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RLVDRALNDAGLKLYEVDAVAATAGPGLIGGLIVGLMTAKALAMAAQKPFYAVNHLEGHA
HHHHHHHHHCCCEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCE
LTARLTDGLPFPYLLLLVSGGHTQMVLVRGIGDYERLGTTIDDALGEAFDKTAKLLGLPY
EEEEECCCCCHHHHHHEECCCCEEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHCCCC
PGGPAVERMALQGDQKRFALPRPLKGEARLDFSFSGLKTAVRQTATELVPLTDQDVTDIC
CCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCHHHHH
ASFQAAVADTLSDRVGRSLERFKTEFPDCATPSLVVAGGVAANKTLRAALENLCTRHGFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCE
FIAPPLNLCTDNAAMIAWAGAERAATQAPDSLDIAPRSRWPLDEKSAPVFGTGRRGAKA
EECCCHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCC
>Mature Secondary Structure
MRVLGIETSCDETAAAIVERDDMGEGRILSNVVLSQIAEHEPYGGVVPEIAARAHVEALD
CEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
RLVDRALNDAGLKLYEVDAVAATAGPGLIGGLIVGLMTAKALAMAAQKPFYAVNHLEGHA
HHHHHHHHHCCCEEEEECHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCE
LTARLTDGLPFPYLLLLVSGGHTQMVLVRGIGDYERLGTTIDDALGEAFDKTAKLLGLPY
EEEEECCCCCHHHHHHEECCCCEEEEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHCCCC
PGGPAVERMALQGDQKRFALPRPLKGEARLDFSFSGLKTAVRQTATELVPLTDQDVTDIC
CCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCHHHHH
ASFQAAVADTLSDRVGRSLERFKTEFPDCATPSLVVAGGVAANKTLRAALENLCTRHGFA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCE
FIAPPLNLCTDNAAMIAWAGAERAATQAPDSLDIAPRSRWPLDEKSAPVFGTGRRGAKA
EECCCHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA