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The map label for this gene is 225853323

Identifier: 225853323

GI number: 225853323

Start: 1838946

End: 1839653

Strand: Reverse

Name: 225853323

Synonym: BMEA_A1939

Alternate gene names: NA

Gene position: 1839653-1838946 (Counterclockwise)

Preceding gene: 225853324

Following gene: 225853322

Centisome position: 86.54

GC content: 58.76

Gene sequence:

>708_bases
ATGAAGCGGGTTCTTGTTACACGGCCTGAGCCGGCAGCAGCGCAAACCGCAGCAAAGCTTCGCGCGGCGGGCTATGAGCC
AGTGCTTCTGCCGTTGAGCCGCACCGTGGCGCTTTCCTTTACCGTTCCCGATGAAGTTTTCGACGCGCTCACCATTACGA
GCGCCAATGCCTTTCGCCATATTGCGCCGGAGCGGCTTTTGCCCTACCGCACGCTGCCGCTTTTTGCTGTGGGTGAGGGG
ACAGCGAAGGCTGCGCAGGAGGCCGGTTTTAAACATGTGATCGAGGGTGGGGGCGATGCCGTTCGCCTTGCCGGGACCAT
GCGGCAGGCGCTGGCGCCAACTGCGCGCGTCCTTTATCTTGCCGGGCGGGTTCGCCAGCCGGTTTTTGAAGATGAGGTGG
CGGCAAATGGTCTTTCAATGATGGTTTGCGATGTCTACGACACTGAGTCGGTCATGTATCCGCCGCAGGCGCTTTCCCGC
ATTCTCGGCCATGCGCCATTTGTCGCGGTGATGCTTTATTCAGGCGTGGCGGCGGCCAGTTTTGTCGAAGCGATGCGCTC
CATTACGCCGCCATTCGATGAGAAGACGCGGTTTTTATGCATTTCGGCGCGGGTTGCGGCCAAATTGCCTTCCAGTTGGC
TGCAACAGGCGCTGGTTTCGGATCATCCAGATGAAAAGGGGCTTTTCCGCTTGTTTTCTAAACTTTGA

Upstream 100 bases:

>100_bases
CAGCCGCGCTCGGCACAGATGCGGCAAACCGCGTGCGCGCCATGGCGGGCCCGCATTTCTTTGATGGGTGGCAGTAGCAT
TGTCGGAGCGGTGAAACCGG

Downstream 100 bases:

>100_bases
CTCTTTTCCGCGCAACCTTCCTTCATCTGAAGATTTTATCTGATAGAGTTTCAGCAACCAATCGGCGATTACGAGAGGAT
CCATGGCGAAATCCGGCACC

Product: uroporphyrinogen-III synthase

Products: uroporphyrinogen III; H2O

Alternate protein names: Uroporphyrinogen-III Synthase Protein; Uroporphyrinogen III Synthase

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKRVLVTRPEPAAAQTAAKLRAAGYEPVLLPLSRTVALSFTVPDEVFDALTITSANAFRHIAPERLLPYRTLPLFAVGEG
TAKAAQEAGFKHVIEGGGDAVRLAGTMRQALAPTARVLYLAGRVRQPVFEDEVAANGLSMMVCDVYDTESVMYPPQALSR
ILGHAPFVAVMLYSGVAAASFVEAMRSITPPFDEKTRFLCISARVAAKLPSSWLQQALVSDHPDEKGLFRLFSKL

Sequences:

>Translated_235_residues
MKRVLVTRPEPAAAQTAAKLRAAGYEPVLLPLSRTVALSFTVPDEVFDALTITSANAFRHIAPERLLPYRTLPLFAVGEG
TAKAAQEAGFKHVIEGGGDAVRLAGTMRQALAPTARVLYLAGRVRQPVFEDEVAANGLSMMVCDVYDTESVMYPPQALSR
ILGHAPFVAVMLYSGVAAASFVEAMRSITPPFDEKTRFLCISARVAAKLPSSWLQQALVSDHPDEKGLFRLFSKL
>Mature_235_residues
MKRVLVTRPEPAAAQTAAKLRAAGYEPVLLPLSRTVALSFTVPDEVFDALTITSANAFRHIAPERLLPYRTLPLFAVGEG
TAKAAQEAGFKHVIEGGGDAVRLAGTMRQALAPTARVLYLAGRVRQPVFEDEVAANGLSMMVCDVYDTESVMYPPQALSR
ILGHAPFVAVMLYSGVAAASFVEAMRSITPPFDEKTRFLCISARVAAKLPSSWLQQALVSDHPDEKGLFRLFSKL

Specific function: Unknown

COG id: COG1587

COG function: function code H; Uroporphyrinogen-III synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.2.1.75

Molecular weight: Translated: 25430; Mature: 25430

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLVTRPEPAAAQTAAKLRAAGYEPVLLPLSRTVALSFTVPDEVFDALTITSANAFRH
CCCEEEECCCCHHHHHHHHHHHCCCCCEEEECCCEEEEEEECCHHHHHHHHHCCCHHHHH
IAPERLLPYRTLPLFAVGEGTAKAAQEAGFKHVIEGGGDAVRLAGTMRQALAPTARVLYL
CCHHHCCCCCCCCEEEECCCHHHHHHHCCHHHHHCCCCCEEHHHHHHHHHHCHHHHHHHH
AGRVRQPVFEDEVAANGLSMMVCDVYDTESVMYPPQALSRILGHAPFVAVMLYSGVAAAS
HHHHCCCCHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
FVEAMRSITPPFDEKTRFLCISARVAAKLPSSWLQQALVSDHPDEKGLFRLFSKL
HHHHHHHCCCCCCCCCEEEEEEHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKRVLVTRPEPAAAQTAAKLRAAGYEPVLLPLSRTVALSFTVPDEVFDALTITSANAFRH
CCCEEEECCCCHHHHHHHHHHHCCCCCEEEECCCEEEEEEECCHHHHHHHHHCCCHHHHH
IAPERLLPYRTLPLFAVGEGTAKAAQEAGFKHVIEGGGDAVRLAGTMRQALAPTARVLYL
CCHHHCCCCCCCCEEEECCCHHHHHHHCCHHHHHCCCCCEEHHHHHHHHHHCHHHHHHHH
AGRVRQPVFEDEVAANGLSMMVCDVYDTESVMYPPQALSRILGHAPFVAVMLYSGVAAAS
HHHHCCCCHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
FVEAMRSITPPFDEKTRFLCISARVAAKLPSSWLQQALVSDHPDEKGLFRLFSKL
HHHHHHHCCCCCCCCCEEEEEEHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: hydroxymethylbilane

Specific reaction: hydroxymethylbilane = uroporphyrinogen III + H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA