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The map label for this gene is pyrH [H]

Identifier: 225852657

GI number: 225852657

Start: 1158760

End: 1159731

Strand: Reverse

Name: pyrH [H]

Synonym: BMEA_A1203

Alternate gene names: 225852657

Gene position: 1159731-1158760 (Counterclockwise)

Preceding gene: 225852658

Following gene: 225852656

Centisome position: 54.56

GC content: 57.51

Gene sequence:

>972_bases
TTGCCCGTATTGCTCTGGGTGAAGGCATCGAAAAGGAAGAAAGCGACTTCGCAGCCGAAGTGGCCGCAGCCGCCAAGGGC
TGATCGGTTTTCCAGCGCATCTTGCCGCGAAAACCGGTTTTCGCTTTTCGGGATGCGTCCATTGCCTGAAAAGCCTCTTG
ATTATGAAGGGCATCGCGTGACAACGCGGTGCCCTTCGTGTATCGCAACCCAAGCACAACCTTCGATCACGATCTGCGGA
GATCATTCCATGACCGGTAAGCCCGCCTACAAGCGCGTCCTGTTAAAAGCTTCAGGTGAAGCATTGATGGGCAGTCAGGG
TTTTGGCATCGACGTCTCGGTGGCCGACCGTATTGCAAACGACATCAAGCAGGCCCGTGCGCTTGGGGTGGAAGTGGGCG
TCGTGATCGGCGGTGGCAATATTTTTCGCGGCGTGGCGGTGGCTTCCAAAGGGGGCGATCGCGTGACGGGCGACCATATG
GGGATGCTTGCGACGGTCATCAATTCACTGGCGCTGCGCACGTCTCTGCACAAGATCGGCGTTGATTCCGTGGTGCTTTC
GGCCATTGCCATGCCTGAAATCTGCGAAAGCTTCTCACAGCGTCAGGCAACCGCCTATATGGATGAAGGCAAGGTGGTAA
TCTTTGCAGGCGGCACGGGCAACCCGTTCTTCACGACCGACTCGGCAGCAGCCTTGCGCGCCGCCGAAATCGAAGCCGAC
GCGCTCCTCAAAGGCACGCAGGTTGACGGCATCTATTCCGCCGATCCAAAGAAAGACCCCGGCGCCACCCGCTTCGAGCA
GCTCACCCACAAGGAAGTTCTCGATCGCGGGCTTGCCGTTATGGATACGGCTGCCGTCGCCCTTGCGCGCGAGAACAACA
TTCTGATAATAGTCTATTCCATCCATGAAAACGGCGGCTTGGCCGATATTCTGCAAGGCAAGGGGCGTTGCACGATTGTT
TCTGACAACTGA

Upstream 100 bases:

>100_bases
CTTCTCTCGCAGGCTTTCGTCATCAATCCGGACCTGACGGTTGAAGCCGCTCTCAAGGATGCCGAAAAGGCTATCGGTGC
ACCGGCCAAGATCACCGGCT

Downstream 100 bases:

>100_bases
TCGTGAACCTTGCTGCGTATTGAAGGAGAAAATGCATGAGCGATGCTTTTGACATCAACGACCTGAAACGCCGCATGGAG
GGCGCTGTCAACGCATTGAA

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MPVLLWVKASKRKKATSQPKWPQPPRADRFSSASCRENRFSLFGMRPLPEKPLDYEGHRVTTRCPSCIATQAQPSITICG
DHSMTGKPAYKRVLLKASGEALMGSQGFGIDVSVADRIANDIKQARALGVEVGVVIGGGNIFRGVAVASKGGDRVTGDHM
GMLATVINSLALRTSLHKIGVDSVVLSAIAMPEICESFSQRQATAYMDEGKVVIFAGGTGNPFFTTDSAAALRAAEIEAD
ALLKGTQVDGIYSADPKKDPGATRFEQLTHKEVLDRGLAVMDTAAVALARENNILIIVYSIHENGGLADILQGKGRCTIV
SDN

Sequences:

>Translated_323_residues
MPVLLWVKASKRKKATSQPKWPQPPRADRFSSASCRENRFSLFGMRPLPEKPLDYEGHRVTTRCPSCIATQAQPSITICG
DHSMTGKPAYKRVLLKASGEALMGSQGFGIDVSVADRIANDIKQARALGVEVGVVIGGGNIFRGVAVASKGGDRVTGDHM
GMLATVINSLALRTSLHKIGVDSVVLSAIAMPEICESFSQRQATAYMDEGKVVIFAGGTGNPFFTTDSAAALRAAEIEAD
ALLKGTQVDGIYSADPKKDPGATRFEQLTHKEVLDRGLAVMDTAAVALARENNILIIVYSIHENGGLADILQGKGRCTIV
SDN
>Mature_322_residues
PVLLWVKASKRKKATSQPKWPQPPRADRFSSASCRENRFSLFGMRPLPEKPLDYEGHRVTTRCPSCIATQAQPSITICGD
HSMTGKPAYKRVLLKASGEALMGSQGFGIDVSVADRIANDIKQARALGVEVGVVIGGGNIFRGVAVASKGGDRVTGDHMG
MLATVINSLALRTSLHKIGVDSVVLSAIAMPEICESFSQRQATAYMDEGKVVIFAGGTGNPFFTTDSAAALRAAEIEADA
LLKGTQVDGIYSADPKKDPGATRFEQLTHKEVLDRGLAVMDTAAVALARENNILIIVYSIHENGGLADILQGKGRCTIVS
DN

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=236, Percent_Identity=53.3898305084746, Blast_Score=267, Evalue=7e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 34411; Mature: 34280

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVLLWVKASKRKKATSQPKWPQPPRADRFSSASCRENRFSLFGMRPLPEKPLDYEGHRV
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEE
TTRCPSCIATQAQPSITICGDHSMTGKPAYKRVLLKASGEALMGSQGFGIDVSVADRIAN
ECCCCCHHCCCCCCCEEEECCCCCCCCHHHHEEEEECCCCEEECCCCCCEEHHHHHHHHH
DIKQARALGVEVGVVIGGGNIFRGVAVASKGGDRVTGDHMGMLATVINSLALRTSLHKIG
HHHHHHHCCEEEEEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
VDSVVLSAIAMPEICESFSQRQATAYMDEGKVVIFAGGTGNPFFTTDSAAALRAAEIEAD
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCCCCCEECCCHHHHHHHHCCHH
ALLKGTQVDGIYSADPKKDPGATRFEQLTHKEVLDRGLAVMDTAAVALARENNILIIVYS
HHCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHEEEECCCEEEEEEE
IHENGGLADILQGKGRCTIVSDN
EECCCCCHHHHCCCCCEEEEECC
>Mature Secondary Structure 
PVLLWVKASKRKKATSQPKWPQPPRADRFSSASCRENRFSLFGMRPLPEKPLDYEGHRV
CEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEE
TTRCPSCIATQAQPSITICGDHSMTGKPAYKRVLLKASGEALMGSQGFGIDVSVADRIAN
ECCCCCHHCCCCCCCEEEECCCCCCCCHHHHEEEEECCCCEEECCCCCCEEHHHHHHHHH
DIKQARALGVEVGVVIGGGNIFRGVAVASKGGDRVTGDHMGMLATVINSLALRTSLHKIG
HHHHHHHCCEEEEEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
VDSVVLSAIAMPEICESFSQRQATAYMDEGKVVIFAGGTGNPFFTTDSAAALRAAEIEAD
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCCCCCEECCCHHHHHHHHCCHH
ALLKGTQVDGIYSADPKKDPGATRFEQLTHKEVLDRGLAVMDTAAVALARENNILIIVYS
HHCCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHEEEECCCEEEEEEE
IHENGGLADILQGKGRCTIVSDN
EECCCCCHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA