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The map label for this gene is frr [H]

Identifier: 225852656

GI number: 225852656

Start: 1158164

End: 1158724

Strand: Reverse

Name: frr [H]

Synonym: BMEA_A1202

Alternate gene names: 225852656

Gene position: 1158724-1158164 (Counterclockwise)

Preceding gene: 225852657

Following gene: 225852655

Centisome position: 54.51

GC content: 58.11

Gene sequence:

>561_bases
ATGAGCGATGCTTTTGACATCAACGACCTGAAACGCCGCATGGAGGGCGCTGTCAACGCATTGAAGCACGACCTTGGCGG
TCTGCGCACCGGGCGCGCTTCGGCAAGCTTGCTGGAGCCGATCACCATCGAAGCCTATGGCTCGACCATGCCGATCAATC
AGGTTGCCAATATCAGCGTACCGGAGTCGCGCATGCTGTCCGTCAGCGTGTGGGACAAGAGCATGGTCGGTGCGGTGGAG
CGTGCAATCCGCGATTCTGGCCTTGGTCTCAACCCGATCACCGACGGGATGACGTTGCGCATTCGCCTGCCGGAGCTGAA
CGAACAGCGCCGCAAGGAATTGGTCAAGATCGCGCATCAATATGCAGAGCAGGGGCGTATCGCTGCCCGCCATGTTCGCC
GCGACGGCATGGACCAGCTGAAAAAGCTGGAGAAGGACAGCGTAATCAGTCAGGATGAAAGCCGGGTTCTGTCCGAAAAG
GTACAGAAGCTGACCGACGATACCATCGCCGAGATGGATAAGATCGTTGCTGTCAAGGAGGGGGAGATCATGCAGGTTTA
G

Upstream 100 bases:

>100_bases
AAAACGGCGGCTTGGCCGATATTCTGCAAGGCAAGGGGCGTTGCACGATTGTTTCTGACAACTGATCGTGAACCTTGCTG
CGTATTGAAGGAGAAAATGC

Downstream 100 bases:

>100_bases
GCCCTGGGCCTGGCATTGCATGATTTTAAAAGGAGAGCTGCGCCATGTCCGATCCGCGCCACATAGCCATTATCATGGAT
GGCAACGGCCGTTGGGCTAA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSDAFDINDLKRRMEGAVNALKHDLGGLRTGRASASLLEPITIEAYGSTMPINQVANISVPESRMLSVSVWDKSMVGAVE
RAIRDSGLGLNPITDGMTLRIRLPELNEQRRKELVKIAHQYAEQGRIAARHVRRDGMDQLKKLEKDSVISQDESRVLSEK
VQKLTDDTIAEMDKIVAVKEGEIMQV

Sequences:

>Translated_186_residues
MSDAFDINDLKRRMEGAVNALKHDLGGLRTGRASASLLEPITIEAYGSTMPINQVANISVPESRMLSVSVWDKSMVGAVE
RAIRDSGLGLNPITDGMTLRIRLPELNEQRRKELVKIAHQYAEQGRIAARHVRRDGMDQLKKLEKDSVISQDESRVLSEK
VQKLTDDTIAEMDKIVAVKEGEIMQV
>Mature_185_residues
SDAFDINDLKRRMEGAVNALKHDLGGLRTGRASASLLEPITIEAYGSTMPINQVANISVPESRMLSVSVWDKSMVGAVER
AIRDSGLGLNPITDGMTLRIRLPELNEQRRKELVKIAHQYAEQGRIAARHVRRDGMDQLKKLEKDSVISQDESRVLSEKV
QKLTDDTIAEMDKIVAVKEGEIMQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=184, Percent_Identity=29.8913043478261, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI291042689, Length=157, Percent_Identity=33.1210191082803, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=46.7391304347826, Blast_Score=163, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24661488, Length=185, Percent_Identity=25.4054054054054, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20723; Mature: 20592

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAFDINDLKRRMEGAVNALKHDLGGLRTGRASASLLEPITIEAYGSTMPINQVANISV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCEEEEECCCCCCHHHHCCCCC
PESRMLSVSVWDKSMVGAVERAIRDSGLGLNPITDGMTLRIRLPELNEQRRKELVKIAHQ
CHHHEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
YAEQGRIAARHVRRDGMDQLKKLEKDSVISQDESRVLSEKVQKLTDDTIAEMDKIVAVKE
HHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GEIMQV
CCEECC
>Mature Secondary Structure 
SDAFDINDLKRRMEGAVNALKHDLGGLRTGRASASLLEPITIEAYGSTMPINQVANISV
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCEEEEECCCCCCHHHHCCCCC
PESRMLSVSVWDKSMVGAVERAIRDSGLGLNPITDGMTLRIRLPELNEQRRKELVKIAHQ
CHHHEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
YAEQGRIAARHVRRDGMDQLKKLEKDSVISQDESRVLSEKVQKLTDDTIAEMDKIVAVKE
HHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GEIMQV
CCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA