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The map label for this gene is trpD

Identifier: 225852639

GI number: 225852639

Start: 1137588

End: 1138607

Strand: Direct

Name: trpD

Synonym: BMEA_A1184

Alternate gene names: 225852639

Gene position: 1137588-1138607 (Clockwise)

Preceding gene: 225852638

Following gene: 225852640

Centisome position: 53.52

GC content: 61.76

Gene sequence:

>1020_bases
ATGGCTGATTTGAAACCCTATATCGCAAAAGCCGCGTCGGGAGAGCCGCTCCCGCTGGGAGATGCAAAAGCCGCTTTCGA
CATCATGATGTCGGGCCAGGCAACGCCCTCGCAAATCGGCGGCTTCCTCATGGCGCTGCGCGTGCGCGGCGAAACGGTGC
CGGAAATCGCCGGTGCGGTGGCTTCCATGAGATCCCGCATGATCCCGGTCATCGCGCCCGATGATGCGATGGATATCGTC
GGCACGGGCGGCGACCAATCCGGTTCCTACAATGTGTCGAGCTGTACGGCGTTCGTCGTGGCCGGTGCGGGCGTACCGGT
TGCCAAACATGGCAACCGCGCGCTTTCGTCCCGCTCCGGCGCAGCCGACGCATTGGCGGCGCTCGGCATCAATATCGAGG
CCGACGCAGACACCATTGGCCGCAGCATCAGCGAAGCCGGTCTCGGCTTCATGTTCGCACCGATGCATCATTCCGCCATG
CGTCATGTGGGCCCTTCCCGCGTGGAATTGGGTACCCGCACGATCTTCAATCTGCTCGGCCCACTTTCCAATCCGGCCAG
TGTCAAACGCCAGCTCGTCGGCGTCTTCGCCCCGCAATGGCTGGAACCGCTGGCCCATGTATTGAAAGAGCTTGGCTCCG
AAACGGCTTGGGTTGTCTACGGTGACGGTCTCGACGAAATGACGACGGCTGGCACCACGCAGGTTGCAGCACTTGAAAAC
GGCCAGATCCGCACCTTTGAAATCACCCCGGAAGAAGTGGGCCTTCGCCGCTGCTCGCCCGCCGAACTGAAGGGGGGCGA
AGCTGCCGAAAATGCCAAGGCCCTTCTTGGCGTTCTGGAGGGCAAGGACAGCGCCTACCGCGATATCGTGCTGCTCAATT
CAGGCGCCGCGCTCGTCGTTGCGGGCAAAGCGGAAAACCTGAAAGACGGAATTGCGCAAGCCGTACAGTCCATCGACAGC
GGCGCAGCCCTTGCGGTTTTGCAAAAGGTCATTGCCGTTTCCAACGACAAGCCGGCCTGA

Upstream 100 bases:

>100_bases
TGCTGCAACAGCTTGTCGGGGAATTGCAGAAGCAATATCCGGTGAAGGTGAACCAGGCCGTCATCAACAGCGCGTTTGCC
TTCTAAAAGCGGTGGATGTG

Downstream 100 bases:

>100_bases
CAGGAAGGATCGCGCCATGTCCACCGATATTCTTCGCAAGATCGAAGCCTATAAGCGGGAAGAAATAGCCGCCGCCAAGG
CGCGTCTTGCCCTTGATGAA

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MADLKPYIAKAASGEPLPLGDAKAAFDIMMSGQATPSQIGGFLMALRVRGETVPEIAGAVASMRSRMIPVIAPDDAMDIV
GTGGDQSGSYNVSSCTAFVVAGAGVPVAKHGNRALSSRSGAADALAALGINIEADADTIGRSISEAGLGFMFAPMHHSAM
RHVGPSRVELGTRTIFNLLGPLSNPASVKRQLVGVFAPQWLEPLAHVLKELGSETAWVVYGDGLDEMTTAGTTQVAALEN
GQIRTFEITPEEVGLRRCSPAELKGGEAAENAKALLGVLEGKDSAYRDIVLLNSGAALVVAGKAENLKDGIAQAVQSIDS
GAALAVLQKVIAVSNDKPA

Sequences:

>Translated_339_residues
MADLKPYIAKAASGEPLPLGDAKAAFDIMMSGQATPSQIGGFLMALRVRGETVPEIAGAVASMRSRMIPVIAPDDAMDIV
GTGGDQSGSYNVSSCTAFVVAGAGVPVAKHGNRALSSRSGAADALAALGINIEADADTIGRSISEAGLGFMFAPMHHSAM
RHVGPSRVELGTRTIFNLLGPLSNPASVKRQLVGVFAPQWLEPLAHVLKELGSETAWVVYGDGLDEMTTAGTTQVAALEN
GQIRTFEITPEEVGLRRCSPAELKGGEAAENAKALLGVLEGKDSAYRDIVLLNSGAALVVAGKAENLKDGIAQAVQSIDS
GAALAVLQKVIAVSNDKPA
>Mature_338_residues
ADLKPYIAKAASGEPLPLGDAKAAFDIMMSGQATPSQIGGFLMALRVRGETVPEIAGAVASMRSRMIPVIAPDDAMDIVG
TGGDQSGSYNVSSCTAFVVAGAGVPVAKHGNRALSSRSGAADALAALGINIEADADTIGRSISEAGLGFMFAPMHHSAMR
HVGPSRVELGTRTIFNLLGPLSNPASVKRQLVGVFAPQWLEPLAHVLKELGSETAWVVYGDGLDEMTTAGTTQVAALENG
QIRTFEITPEEVGLRRCSPAELKGGEAAENAKALLGVLEGKDSAYRDIVLLNSGAALVVAGKAENLKDGIAQAVQSIDSG
AALAVLQKVIAVSNDKPA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=321, Percent_Identity=38.3177570093458, Blast_Score=215, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6320561, Length=327, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=4e-36,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_BRUA1 (B2S5Z0)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935061.1
- ProteinModelPortal:   B2S5Z0
- SMR:   B2S5Z0
- GeneID:   6328629
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I10800
- HOGENOM:   HBG559996
- OMA:   ATPSQMG
- ProtClustDB:   PRK00188
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 34839; Mature: 34708

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLKPYIAKAASGEPLPLGDAKAAFDIMMSGQATPSQIGGFLMALRVRGETVPEIAGAV
CCCCCHHHHHCCCCCCCCCCCCHHHHHHEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
ASMRSRMIPVIAPDDAMDIVGTGGDQSGSYNVSSCTAFVVAGAGVPVAKHGNRALSSRSG
HHHHHCCCEEECCCCCEEEEECCCCCCCCCCHHHHEEEEEECCCCCCCCCCCHHHHCCCC
AADALAALGINIEADADTIGRSISEAGLGFMFAPMHHSAMRHVGPSRVELGTRTIFNLLG
HHHHHHHHCCCEECCHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCHHHHHHHHHHHHHC
PLSNPASVKRQLVGVFAPQWLEPLAHVLKELGSETAWVVYGDGLDEMTTAGTTQVAALEN
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCEEEEEECC
GQIRTFEITPEEVGLRRCSPAELKGGEAAENAKALLGVLEGKDSAYRDIVLLNSGAALVV
CCEEEEEECHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEE
AGKAENLKDGIAQAVQSIDSGAALAVLQKVIAVSNDKPA
ECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ADLKPYIAKAASGEPLPLGDAKAAFDIMMSGQATPSQIGGFLMALRVRGETVPEIAGAV
CCCCHHHHHCCCCCCCCCCCCHHHHHHEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
ASMRSRMIPVIAPDDAMDIVGTGGDQSGSYNVSSCTAFVVAGAGVPVAKHGNRALSSRSG
HHHHHCCCEEECCCCCEEEEECCCCCCCCCCHHHHEEEEEECCCCCCCCCCCHHHHCCCC
AADALAALGINIEADADTIGRSISEAGLGFMFAPMHHSAMRHVGPSRVELGTRTIFNLLG
HHHHHHHHCCCEECCHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCHHHHHHHHHHHHHC
PLSNPASVKRQLVGVFAPQWLEPLAHVLKELGSETAWVVYGDGLDEMTTAGTTQVAALEN
CCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCEEEEEECC
GQIRTFEITPEEVGLRRCSPAELKGGEAAENAKALLGVLEGKDSAYRDIVLLNSGAALVV
CCEEEEEECHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEE
AGKAENLKDGIAQAVQSIDSGAALAVLQKVIAVSNDKPA
ECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA