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The map label for this gene is ppiD [H]

Identifier: 225852638

GI number: 225852638

Start: 1135687

End: 1137573

Strand: Direct

Name: ppiD [H]

Synonym: BMEA_A1183

Alternate gene names: 225852638

Gene position: 1135687-1137573 (Clockwise)

Preceding gene: 225852622

Following gene: 225852639

Centisome position: 53.43

GC content: 59.19

Gene sequence:

>1887_bases
ATGCTCGATAGCCTGCGTTCCGCCGCTCAATCCTGGATCGCCAAACTTTTGCTTGGCCTGCTTGTGCTAAGCTTTGCGAT
CTGGGGCATCTCGGATGTCTTCCGTGGCGGCATGGCAGGCAACGCCGCGCTGACAGCCGGTGATTCCGAGGTCAGCGCGA
CCGATTATCGCTTTGCCTACGAACAGCAGCTTATGCGCCTTTCGCAGCAGTTCCGCCAGCGGCTCACCCGCGAACAGGCC
AAGGCAATCGGCGTCGAGAACCAGGTTCTGGCCCAGCTTGCCGCCGGTGTCGTGCTGGATGAAGCAGCCCGCAACATGCA
GCTTGGCCTTTCCCAGGACGCCATTGCCCGCCTGACCGCCGAAGATCCCGCCTTCCATGATGCAGGCGGCAATTTCAACC
GCGCGCGGTTTGATGCGGTTTTGCGCCAGTCCGGCATTCGCGCCGAGGATTATCTGGAAAACCGTGCGAAAGTCGCCCGC
CGCCAGCAGATCGTCGAAGCAGCAACGGACGGCATGAAACTGCCGGATACGATGCTGAAGGCACTTGCCCTCTATCAGGG
CGAAAGCCGCAGCGCCGACTATATCGATGTGCCTGCCGAAAAGGCCGACGCCATTCCCGCACCGTCAGAGGATGTGCTCA
AGGCCTATTTTGAAGCGCACAAGGAAGATTACAAGGCGCCGGAATATCGCAAGATCAGCTATGTGAAGCTGGAGCCGTCC
GATATTGCCGACCCTGCCGCCGTCACGCAGGATGAGATCAGCGAATATTATGAAAAGAACAAGGCCCGTTTCAGCACGCC
TAAGACGCGCACCATCGAACAGCTGAACTTTGCCGACGATGCCGCCGCTGAAGCCGCCCACCAGAAGATCGAGGCAGGCA
CCAGCTTCCTCGATATCGGCAAGGAACAGGGCAAGACCGAAAGCGATCTGACGCTCGGCACTTTTGAAAAATCCGGCATT
CCCGACCAGACCATTGCCGACGCCGCCTTCGCGCTTGGCGAAGGTGCGGTCAGCCCGGTTGTCAAGGGAATCTTCGGCCC
GGTCCTGCTGCGTGTAACGAAAATCAACCCGGCGCATGAGAAGCCGCTTTCCGAAGTCGAAGGAGAAATCCGCAACACGC
TCGCCACCAATATTGCAGCCAGCAGCATCAACAGCCTGCACGATTCCTATGAGCAGGAACGTTCGGACGGGGCAACCATG
GCCGATGTCGCCAAAAAGCTGCACCTGAAAATGGTAACGGTCGATGCAATCGATGCCGAAGGCGACGATCCTGCGGGCAA
GCCTGTTGAACTGCCGAATGCGCAGGCGCTGCTTCCAGCCGTCTTTCAGGCTGAACAGGGCTTCGACAACGACCCGCTCA
CCATGGGTAATATCGGCTATCTCTGGTATCAGGTGGATGGCGTTACCCCTGCCCGCGACCGCACGCTCGATGAAGTCAAG
GACAAGGTCGTGGCGGCATGGAAGGGCGAGGAAGCCGTCAAGCGCCTCAACCAGCGCATGGAAGAATTGAAGAAGCGCGT
CGAAGACGGCGCAACGCTTGACACAATCGCTTCCGAACTGGGCCTTGAAAAGCAGACCAAGCGCGGCATCACCCGCACCA
CCAACGACGCCGACATCGGTTCGGCTGCAACCGCGCAGATTTTCCGTGGCGCGAACGGTCTGGTCGGCACGGCTGCCGCG
CCCTCCGACGATGCGCAAATTCTCTTCAAGGTAACGGAGGTCACCAAACCTGCCGCCGCCGGACCGGAAGCAATCCCGGA
AGATCAGCAGAAATATCTGGCGACCGCGCTTGCGGATGATATGCTGCAACAGCTTGTCGGGGAATTGCAGAAGCAATATC
CGGTGAAGGTGAACCAGGCCGTCATCAACAGCGCGTTTGCCTTCTAA

Upstream 100 bases:

>100_bases
TCAACACAATGAGACCTTGCATATGGGGCTTGCTTGAGGTTATCCCCTGACTGGCTCATTTTATAAAGCCAAGCTTCAAT
TTGTTCTTGAAGGGTTTACA

Downstream 100 bases:

>100_bases
AAGCGGTGGATGTGATGGCTGATTTGAAACCCTATATCGCAAAAGCCGCGTCGGGAGAGCCGCTCCCGCTGGGAGATGCA
AAAGCCGCTTTCGACATCAT

Product: rotamase family protein

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 628; Mature: 628

Protein sequence:

>628_residues
MLDSLRSAAQSWIAKLLLGLLVLSFAIWGISDVFRGGMAGNAALTAGDSEVSATDYRFAYEQQLMRLSQQFRQRLTREQA
KAIGVENQVLAQLAAGVVLDEAARNMQLGLSQDAIARLTAEDPAFHDAGGNFNRARFDAVLRQSGIRAEDYLENRAKVAR
RQQIVEAATDGMKLPDTMLKALALYQGESRSADYIDVPAEKADAIPAPSEDVLKAYFEAHKEDYKAPEYRKISYVKLEPS
DIADPAAVTQDEISEYYEKNKARFSTPKTRTIEQLNFADDAAAEAAHQKIEAGTSFLDIGKEQGKTESDLTLGTFEKSGI
PDQTIADAAFALGEGAVSPVVKGIFGPVLLRVTKINPAHEKPLSEVEGEIRNTLATNIAASSINSLHDSYEQERSDGATM
ADVAKKLHLKMVTVDAIDAEGDDPAGKPVELPNAQALLPAVFQAEQGFDNDPLTMGNIGYLWYQVDGVTPARDRTLDEVK
DKVVAAWKGEEAVKRLNQRMEELKKRVEDGATLDTIASELGLEKQTKRGITRTTNDADIGSAATAQIFRGANGLVGTAAA
PSDDAQILFKVTEVTKPAAAGPEAIPEDQQKYLATALADDMLQQLVGELQKQYPVKVNQAVINSAFAF

Sequences:

>Translated_628_residues
MLDSLRSAAQSWIAKLLLGLLVLSFAIWGISDVFRGGMAGNAALTAGDSEVSATDYRFAYEQQLMRLSQQFRQRLTREQA
KAIGVENQVLAQLAAGVVLDEAARNMQLGLSQDAIARLTAEDPAFHDAGGNFNRARFDAVLRQSGIRAEDYLENRAKVAR
RQQIVEAATDGMKLPDTMLKALALYQGESRSADYIDVPAEKADAIPAPSEDVLKAYFEAHKEDYKAPEYRKISYVKLEPS
DIADPAAVTQDEISEYYEKNKARFSTPKTRTIEQLNFADDAAAEAAHQKIEAGTSFLDIGKEQGKTESDLTLGTFEKSGI
PDQTIADAAFALGEGAVSPVVKGIFGPVLLRVTKINPAHEKPLSEVEGEIRNTLATNIAASSINSLHDSYEQERSDGATM
ADVAKKLHLKMVTVDAIDAEGDDPAGKPVELPNAQALLPAVFQAEQGFDNDPLTMGNIGYLWYQVDGVTPARDRTLDEVK
DKVVAAWKGEEAVKRLNQRMEELKKRVEDGATLDTIASELGLEKQTKRGITRTTNDADIGSAATAQIFRGANGLVGTAAA
PSDDAQILFKVTEVTKPAAAGPEAIPEDQQKYLATALADDMLQQLVGELQKQYPVKVNQAVINSAFAF
>Mature_628_residues
MLDSLRSAAQSWIAKLLLGLLVLSFAIWGISDVFRGGMAGNAALTAGDSEVSATDYRFAYEQQLMRLSQQFRQRLTREQA
KAIGVENQVLAQLAAGVVLDEAARNMQLGLSQDAIARLTAEDPAFHDAGGNFNRARFDAVLRQSGIRAEDYLENRAKVAR
RQQIVEAATDGMKLPDTMLKALALYQGESRSADYIDVPAEKADAIPAPSEDVLKAYFEAHKEDYKAPEYRKISYVKLEPS
DIADPAAVTQDEISEYYEKNKARFSTPKTRTIEQLNFADDAAAEAAHQKIEAGTSFLDIGKEQGKTESDLTLGTFEKSGI
PDQTIADAAFALGEGAVSPVVKGIFGPVLLRVTKINPAHEKPLSEVEGEIRNTLATNIAASSINSLHDSYEQERSDGATM
ADVAKKLHLKMVTVDAIDAEGDDPAGKPVELPNAQALLPAVFQAEQGFDNDPLTMGNIGYLWYQVDGVTPARDRTLDEVK
DKVVAAWKGEEAVKRLNQRMEELKKRVEDGATLDTIASELGLEKQTKRGITRTTNDADIGSAATAQIFRGANGLVGTAAA
PSDDAQILFKVTEVTKPAAAGPEAIPEDQQKYLATALADDMLQQLVGELQKQYPVKVNQAVINSAFAF

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=413, Percent_Identity=27.8450363196126, Blast_Score=143, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68080; Mature: 68080

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSLRSAAQSWIAKLLLGLLVLSFAIWGISDVFRGGMAGNAALTAGDSEVSATDYRFAY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHH
EQQLMRLSQQFRQRLTREQAKAIGVENQVLAQLAAGVVLDEAARNMQLGLSQDAIARLTA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
EDPAFHDAGGNFNRARFDAVLRQSGIRAEDYLENRAKVARRQQIVEAATDGMKLPDTMLK
CCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ALALYQGESRSADYIDVPAEKADAIPAPSEDVLKAYFEAHKEDYKAPEYRKISYVKLEPS
HHHHHCCCCCCCCEEECCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
DIADPAAVTQDEISEYYEKNKARFSTPKTRTIEQLNFADDAAAEAAHQKIEAGTSFLDIG
CCCCCHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHCC
KEQGKTESDLTLGTFEKSGIPDQTIADAAFALGEGAVSPVVKGIFGPVLLRVTKINPAHE
HHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHC
KPLSEVEGEIRNTLATNIAASSINSLHDSYEQERSDGATMADVAKKLHLKMVTVDAIDAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEEEECCC
GDDPAGKPVELPNAQALLPAVFQAEQGFDNDPLTMGNIGYLWYQVDGVTPARDRTLDEVK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCEEEEEEECCCCCHHHCHHHHHH
DKVVAAWKGEEAVKRLNQRMEELKKRVEDGATLDTIASELGLEKQTKRGITRTTNDADIG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
SAATAQIFRGANGLVGTAAAPSDDAQILFKVTEVTKPAAAGPEAIPEDQQKYLATALADD
CHHHHHHHHCCCCCEECCCCCCCCHHEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
MLQQLVGELQKQYPVKVNQAVINSAFAF
HHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLDSLRSAAQSWIAKLLLGLLVLSFAIWGISDVFRGGMAGNAALTAGDSEVSATDYRFAY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHH
EQQLMRLSQQFRQRLTREQAKAIGVENQVLAQLAAGVVLDEAARNMQLGLSQDAIARLTA
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
EDPAFHDAGGNFNRARFDAVLRQSGIRAEDYLENRAKVARRQQIVEAATDGMKLPDTMLK
CCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ALALYQGESRSADYIDVPAEKADAIPAPSEDVLKAYFEAHKEDYKAPEYRKISYVKLEPS
HHHHHCCCCCCCCEEECCCHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCC
DIADPAAVTQDEISEYYEKNKARFSTPKTRTIEQLNFADDAAAEAAHQKIEAGTSFLDIG
CCCCCHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHCC
KEQGKTESDLTLGTFEKSGIPDQTIADAAFALGEGAVSPVVKGIFGPVLLRVTKINPAHE
HHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHC
KPLSEVEGEIRNTLATNIAASSINSLHDSYEQERSDGATMADVAKKLHLKMVTVDAIDAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEEEEEEEECCC
GDDPAGKPVELPNAQALLPAVFQAEQGFDNDPLTMGNIGYLWYQVDGVTPARDRTLDEVK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCEEEEEEECCCCCHHHCHHHHHH
DKVVAAWKGEEAVKRLNQRMEELKKRVEDGATLDTIASELGLEKQTKRGITRTTNDADIG
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHCCCCCCCCCCCCC
SAATAQIFRGANGLVGTAAAPSDDAQILFKVTEVTKPAAAGPEAIPEDQQKYLATALADD
CHHHHHHHHCCCCCEECCCCCCCCHHEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
MLQQLVGELQKQYPVKVNQAVINSAFAF
HHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]