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The map label for this gene is folB [H]

Identifier: 225852534

GI number: 225852534

Start: 1015363

End: 1015722

Strand: Direct

Name: folB [H]

Synonym: BMEA_A1071

Alternate gene names: 225852534

Gene position: 1015363-1015722 (Clockwise)

Preceding gene: 225852533

Following gene: 225852535

Centisome position: 47.77

GC content: 52.78

Gene sequence:

>360_bases
GTGTACACGATCCGCATCATGAACTGTGCCTTTTTTGCGCATCACGGTGTCTTCGATGAAGAACACAAGCTCGGACAACG
ATTCTATGTCGATGCCGTTCTGGATGTTGATGAGGGCAACTCGCTGGAAAGCGACAATATTGACGGAACAGTTCATTACG
GAATTGCCTTCTCCGTCATTGAAGGCATCATCATGGGCCGCCAGCGTTATCTGATCGAAACCCTCGCGCTTGATGTCGCC
AAGGCGCTCGTCGCACGGTTTCCTCAGATAAAGCGGGCTGAGATCACGATCCGCAAGCCGAATGCCCCGGTTTCGGGCGT
CCTCGATTATGTGGAAGTAACCGTGGTTTACCCCCAGTGA

Upstream 100 bases:

>100_bases
CTTCCGTGTTCACAATGTCGCTTTTAACAGAGATGCACTTGCAGTTGCGGATGCTATCCTGCAAAGCAACGTCAGGATCT
AACAATAGGAAGTGAAGCCC

Downstream 100 bases:

>100_bases
GCACTCCGCCGAAACCATTGCGCGCCTGGCTTGGCCTCGGCGGCAATATCGATGATCCGATCATCTCCATGGCGAGCGCG
CTTCGTATGCTGGATGGACG

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MYTIRIMNCAFFAHHGVFDEEHKLGQRFYVDAVLDVDEGNSLESDNIDGTVHYGIAFSVIEGIIMGRQRYLIETLALDVA
KALVARFPQIKRAEITIRKPNAPVSGVLDYVEVTVVYPQ

Sequences:

>Translated_119_residues
MYTIRIMNCAFFAHHGVFDEEHKLGQRFYVDAVLDVDEGNSLESDNIDGTVHYGIAFSVIEGIIMGRQRYLIETLALDVA
KALVARFPQIKRAEITIRKPNAPVSGVLDYVEVTVVYPQ
>Mature_119_residues
MYTIRIMNCAFFAHHGVFDEEHKLGQRFYVDAVLDVDEGNSLESDNIDGTVHYGIAFSVIEGIIMGRQRYLIETLALDVA
KALVARFPQIKRAEITIRKPNAPVSGVLDYVEVTVVYPQ

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13402; Mature: 13402

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTIRIMNCAFFAHHGVFDEEHKLGQRFYVDAVLDVDEGNSLESDNIDGTVHYGIAFSVI
CEEEEEEEEEEEHHCCCCCCHHHCCCEEEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHH
EGIIMGRQRYLIETLALDVAKALVARFPQIKRAEITIRKPNAPVSGVLDYVEVTVVYPQ
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHEEEEEEEEEECC
>Mature Secondary Structure
MYTIRIMNCAFFAHHGVFDEEHKLGQRFYVDAVLDVDEGNSLESDNIDGTVHYGIAFSVI
CEEEEEEEEEEEHHCCCCCCHHHCCCEEEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHH
EGIIMGRQRYLIETLALDVAKALVARFPQIKRAEITIRKPNAPVSGVLDYVEVTVVYPQ
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9168622 [H]