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The map label for this gene is aspS [H]

Identifier: 225852268

GI number: 225852268

Start: 758439

End: 760226

Strand: Direct

Name: aspS [H]

Synonym: BMEA_A0791

Alternate gene names: 225852268

Gene position: 758439-760226 (Clockwise)

Preceding gene: 225852266

Following gene: 225852270

Centisome position: 35.68

GC content: 58.45

Gene sequence:

>1788_bases
ATGCACCGTTACCGCAGCCATACCTGCGCAGCCCTTCGCAAGACGGACGTTGGTTCTAATGTCCGTCTGTCCGGCTGGGT
TCACCGCGTCCGTGACCATGGCGGCATTCTCTTCATCGATCTTCGCGATCATTACGGCATTACCCAGATTGTGGCCGATC
CTGATTCGCCCGCGTTCAAGGTTGCCGAAACCGTTCGCGGCGAGTGGGTCATCCGCGTCGATGGTGAAGTGAAGGCTCGC
GCCGACGATGCGGTCAATACGAACCTGCCGACCGGCGAAGTCGAAATCTTCGCAACCGAAATCGAAGTGCTTTCGCCTGC
GAAGGAACTGCCGCTGCCGGTTTTCGGCGAGCCGGACTATCCGGAAGATATTCGCCTGAAATACCGCTTCCTCGATTTGC
GCCGCGAAACGCTGCACAAGAACATCATGAGCCGCACAAAGATCATCGCCGCGATGCGTCGCCGCATGACCGAAATCGGC
TTCAATGAATTCTCCACGCCGATCCTGACGGCTTCCTCGCCGGAAGGCGCGCGCGACTTCCTCGTGCCGAGCCGCATTCA
TCCCGGAAAATTCTATGCGCTGCCGCAGGCGCCGCAGCAGTACAAGCAGCTTCTGATGGTGGCCGGTTTCGACCGCTATT
TCCAGATTGCGCCCTGCTTCCGCGATGAAGACCCGCGTGCCGACCGCCTGCCGGGCGAGTTCTATCAGCTCGACCTTGAA
ATGAGCTTCGTGACCCAGGAAGAAGTCTGGGAAACCATGGAACCCGTCATGCGCGGCATTTTTGAAGAATTTGCCGAAGG
CAAGCCGGTGACGAAAGTGTTCCGCCGCATCGCTTATGACGACGCGATCCGCACCTATGGTTCGGACAAGCCGGACCTGC
GCAACCCGATTGAGATGCAGGCCGTGACCGACCATTTCGCCGGATCGGGCTTCAAGGTCTTCGCAAACATGATCGCCAAC
GACGCAAAAGTCGAAGTCTGGGCCATTCCGGCCAAGACCGGCGGCTCCAGAGCTTTCTGCGACCGCATGAATTCCTGGGC
GCAGAGCGAAGGCCAGCCGGGCCTTGGCTATATCTTCTGGCGCAAGGAAGGCGACAAGCTTGAAGGCGCTGGCCCGATCG
CCAAGAATATCGGCGAAGAGCGCACCGAAGCGATCCGCAAGCAGATGGGCCTTGAAGACGGCGATGCCTGCTTCTTCGTG
GCTGGCCTGCCGTCCAAGTTCTACAAATTCGCAGGCGATGCCCGCACCCGCGCAGGCGAAGAACTGAATCTCGTCGATCG
CGACCGTTTTGAACTGGCTTGGATTATCGATTTCCCGTTCTACGAATGGGACGAGGACAACAAGAAGATCGACTTTGCGC
ATAATCCGTTCTCCATGCCGCAGGGTGGCATGGATGCGCTGGAAAACATGGACCCGCTGGAAATTAAGGCCTATCAGTAC
GATCTCGTCTGCAATGGTTTTGAAATTGCCTCCGGCTCGATCCGTAACCAGTTGCCGGAAGTCATGGTCAAGGCTTTCGA
GAAGGTGGGTCTCAGCCAGCAGGACGTGGAAGAGCGTTTCGGCGGCCTTTACCGTGCCTTCCAATATGGTGCGCCTCCGC
ATGGCGGCATGGCGGCCGGCATCGACCGTGTCATCATGTTGCTTGTCGGCGCGAAGAACCTGCGTGAAATCTCGCTCTTC
CCGATGAACCAGCAGGCGCTTGATCTTCTGATGGGCGCGCCTTCGGAAGTTTCACCGGCACAGCTTCGTGACCTGCATGT
GCGCCTGGCGCCAGTGCAAAAGAGCTAA

Upstream 100 bases:

>100_bases
TACAGTGCAGACTTGACAAAACCCGGTCAAAATGCGCTTTTCCGCCAGAATTTGCAGCGCTTGCCTGCACTGACTTATCC
TATTCCAAAAGGCAGAAATC

Downstream 100 bases:

>100_bases
ACTGATAGAAAAACCCGGTCTTGAGCCGGGCTTTTTGACTTTAATTGTCGGCCTCCACACTGATTTTCAAAAGCTGGATG
ATCTTTGTCGGGTCCAGCGA

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 595; Mature: 595

Protein sequence:

>595_residues
MHRYRSHTCAALRKTDVGSNVRLSGWVHRVRDHGGILFIDLRDHYGITQIVADPDSPAFKVAETVRGEWVIRVDGEVKAR
ADDAVNTNLPTGEVEIFATEIEVLSPAKELPLPVFGEPDYPEDIRLKYRFLDLRRETLHKNIMSRTKIIAAMRRRMTEIG
FNEFSTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMVAGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLE
MSFVTQEEVWETMEPVMRGIFEEFAEGKPVTKVFRRIAYDDAIRTYGSDKPDLRNPIEMQAVTDHFAGSGFKVFANMIAN
DAKVEVWAIPAKTGGSRAFCDRMNSWAQSEGQPGLGYIFWRKEGDKLEGAGPIAKNIGEERTEAIRKQMGLEDGDACFFV
AGLPSKFYKFAGDARTRAGEELNLVDRDRFELAWIIDFPFYEWDEDNKKIDFAHNPFSMPQGGMDALENMDPLEIKAYQY
DLVCNGFEIASGSIRNQLPEVMVKAFEKVGLSQQDVEERFGGLYRAFQYGAPPHGGMAAGIDRVIMLLVGAKNLREISLF
PMNQQALDLLMGAPSEVSPAQLRDLHVRLAPVQKS

Sequences:

>Translated_595_residues
MHRYRSHTCAALRKTDVGSNVRLSGWVHRVRDHGGILFIDLRDHYGITQIVADPDSPAFKVAETVRGEWVIRVDGEVKAR
ADDAVNTNLPTGEVEIFATEIEVLSPAKELPLPVFGEPDYPEDIRLKYRFLDLRRETLHKNIMSRTKIIAAMRRRMTEIG
FNEFSTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMVAGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLE
MSFVTQEEVWETMEPVMRGIFEEFAEGKPVTKVFRRIAYDDAIRTYGSDKPDLRNPIEMQAVTDHFAGSGFKVFANMIAN
DAKVEVWAIPAKTGGSRAFCDRMNSWAQSEGQPGLGYIFWRKEGDKLEGAGPIAKNIGEERTEAIRKQMGLEDGDACFFV
AGLPSKFYKFAGDARTRAGEELNLVDRDRFELAWIIDFPFYEWDEDNKKIDFAHNPFSMPQGGMDALENMDPLEIKAYQY
DLVCNGFEIASGSIRNQLPEVMVKAFEKVGLSQQDVEERFGGLYRAFQYGAPPHGGMAAGIDRVIMLLVGAKNLREISLF
PMNQQALDLLMGAPSEVSPAQLRDLHVRLAPVQKS
>Mature_595_residues
MHRYRSHTCAALRKTDVGSNVRLSGWVHRVRDHGGILFIDLRDHYGITQIVADPDSPAFKVAETVRGEWVIRVDGEVKAR
ADDAVNTNLPTGEVEIFATEIEVLSPAKELPLPVFGEPDYPEDIRLKYRFLDLRRETLHKNIMSRTKIIAAMRRRMTEIG
FNEFSTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMVAGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLE
MSFVTQEEVWETMEPVMRGIFEEFAEGKPVTKVFRRIAYDDAIRTYGSDKPDLRNPIEMQAVTDHFAGSGFKVFANMIAN
DAKVEVWAIPAKTGGSRAFCDRMNSWAQSEGQPGLGYIFWRKEGDKLEGAGPIAKNIGEERTEAIRKQMGLEDGDACFFV
AGLPSKFYKFAGDARTRAGEELNLVDRDRFELAWIIDFPFYEWDEDNKKIDFAHNPFSMPQGGMDALENMDPLEIKAYQY
DLVCNGFEIASGSIRNQLPEVMVKAFEKVGLSQQDVEERFGGLYRAFQYGAPPHGGMAAGIDRVIMLLVGAKNLREISLF
PMNQQALDLLMGAPSEVSPAQLRDLHVRLAPVQKS

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI40789249, Length=598, Percent_Identity=33.2775919732441, Blast_Score=324, Evalue=1e-88,
Organism=Homo sapiens, GI45439306, Length=271, Percent_Identity=29.1512915129151, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI194272210, Length=274, Percent_Identity=27.7372262773723, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI5031815, Length=274, Percent_Identity=27.7372262773723, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI226491502, Length=255, Percent_Identity=24.7058823529412, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1788173, Length=589, Percent_Identity=41.0865874363328, Blast_Score=437, Evalue=1e-123,
Organism=Escherichia coli, GI1790571, Length=290, Percent_Identity=28.9655172413793, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789256, Length=301, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI32566633, Length=602, Percent_Identity=32.2259136212625, Blast_Score=273, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17551876, Length=302, Percent_Identity=27.1523178807947, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71984122, Length=292, Percent_Identity=26.3698630136986, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994340, Length=244, Percent_Identity=26.6393442622951, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17535925, Length=244, Percent_Identity=26.6393442622951, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17535927, Length=244, Percent_Identity=26.6393442622951, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325153, Length=661, Percent_Identity=28.1391830559758, Blast_Score=214, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6323011, Length=271, Percent_Identity=29.1512915129151, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321807, Length=290, Percent_Identity=23.1034482758621, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24584738, Length=606, Percent_Identity=33.1683168316832, Blast_Score=299, Evalue=4e-81,
Organism=Drosophila melanogaster, GI17136276, Length=262, Percent_Identity=29.7709923664122, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24640849, Length=260, Percent_Identity=26.5384615384615, Blast_Score=76, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24640851, Length=260, Percent_Identity=26.5384615384615, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19921528, Length=281, Percent_Identity=27.0462633451957, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 67273; Mature: 67273

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRYRSHTCAALRKTDVGSNVRLSGWVHRVRDHGGILFIDLRDHYGITQIVADPDSPAFK
CCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCHHH
VAETVRGEWVIRVDGEVKARADDAVNTNLPTGEVEIFATEIEVLSPAKELPLPVFGEPDY
HHHHCCCCEEEEECCCEEECCCCCCCCCCCCCCEEEEEEEHHHHCCHHHCCCCCCCCCCC
PEDIRLKYRFLDLRRETLHKNIMSRTKIIAAMRRRMTEIGFNEFSTPILTASSPEGARDF
CHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHC
LVPSRIHPGKFYALPQAPQQYKQLLMVAGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLE
CCCCCCCCCCEEECCCCHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCEEEEEEE
MSFVTQEEVWETMEPVMRGIFEEFAEGKPVTKVFRRIAYDDAIRTYGSDKPDLRNPIEMQ
EEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
AVTDHFAGSGFKVFANMIANDAKVEVWAIPAKTGGSRAFCDRMNSWAQSEGQPGLGYIFW
HHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEE
RKEGDKLEGAGPIAKNIGEERTEAIRKQMGLEDGDACFFVAGLPSKFYKFAGDARTRAGE
ECCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCHHHCCCC
ELNLVDRDRFELAWIIDFPFYEWDEDNKKIDFAHNPFSMPQGGMDALENMDPLEIKAYQY
CCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCHHHHCCCCCCEEEEEEE
DLVCNGFEIASGSIRNQLPEVMVKAFEKVGLSQQDVEERFGGLYRAFQYGAPPHGGMAAG
EEEECCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IDRVIMLLVGAKNLREISLFPMNQQALDLLMGAPSEVSPAQLRDLHVRLAPVQKS
HHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCCHHHHHEEEEEEECCCCC
>Mature Secondary Structure
MHRYRSHTCAALRKTDVGSNVRLSGWVHRVRDHGGILFIDLRDHYGITQIVADPDSPAFK
CCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCHHH
VAETVRGEWVIRVDGEVKARADDAVNTNLPTGEVEIFATEIEVLSPAKELPLPVFGEPDY
HHHHCCCCEEEEECCCEEECCCCCCCCCCCCCCEEEEEEEHHHHCCHHHCCCCCCCCCCC
PEDIRLKYRFLDLRRETLHKNIMSRTKIIAAMRRRMTEIGFNEFSTPILTASSPEGARDF
CHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHC
LVPSRIHPGKFYALPQAPQQYKQLLMVAGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLE
CCCCCCCCCCEEECCCCHHHHHHHHHHHCCCHHEEECCCCCCCCCCCCCCCCCEEEEEEE
MSFVTQEEVWETMEPVMRGIFEEFAEGKPVTKVFRRIAYDDAIRTYGSDKPDLRNPIEMQ
EEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
AVTDHFAGSGFKVFANMIANDAKVEVWAIPAKTGGSRAFCDRMNSWAQSEGQPGLGYIFW
HHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEE
RKEGDKLEGAGPIAKNIGEERTEAIRKQMGLEDGDACFFVAGLPSKFYKFAGDARTRAGE
ECCCCCCCCCCCHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCHHHCCCC
ELNLVDRDRFELAWIIDFPFYEWDEDNKKIDFAHNPFSMPQGGMDALENMDPLEIKAYQY
CCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCHHHHCCCCCCEEEEEEE
DLVCNGFEIASGSIRNQLPEVMVKAFEKVGLSQQDVEERFGGLYRAFQYGAPPHGGMAAG
EEEECCEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IDRVIMLLVGAKNLREISLFPMNQQALDLLMGAPSEVSPAQLRDLHVRLAPVQKS
HHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCCHHHHHEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA