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The map label for this gene is rnc

Identifier: 225852182

GI number: 225852182

Start: 671902

End: 672639

Strand: Direct

Name: rnc

Synonym: BMEA_A0698

Alternate gene names: 225852182

Gene position: 671902-672639 (Clockwise)

Preceding gene: 225852181

Following gene: 225852183

Centisome position: 31.61

GC content: 58.81

Gene sequence:

>738_bases
GTGAACCGCACACGGCCGTTACCGGAAATTAAGATGGTTTCGGCAAACAAGACTGCATCGATATTGGAAGAGCGCACAGG
CCACCGTTTCCTCAATCTGAAACGGCTGGAACGCGCGCTCACCCATTCAAGCGTACAGGCGCCCGCGCGCGCCAATTATG
AAAGACTGGAGTTTCTGGGCGACCGCGTGCTGGGCCTGACGGTTGCCGAAATGCTGTTCGAGGCTTTCCCGGAAGCATCG
GAAGGCGAATTGTCCGTGCGTCTCAACGCGCTGGTCAATGCCGAGACATGTGCCGCCATTGCCGATGAAATCGGCCTTGC
CGATCTCATTCATACCGGCTCCGACATCAAATCGTTGAACGACAAGCGCCTCCTGAATGTGCGCGCCGACGTGGTTGAGG
CGCTGATCGCCACCATCTATCTCGACGGCGGGCTGGAAGCGGCGCGGTCTTTCATCCAGCGTTACTGGAAAAAGCGTTCG
CTCGAAACGGGTGCAGCGCGCCGCGATGCCAAGACCGAATTGCAGGAATGGGCGCACCAGCAGGGCAATGTTCACCCGGT
CTATGCCATTTTGAGCCGCTCCGGCCCGGATCATGATCCGCTGTTTCTGGTGGAAGTGACGGTGAAGGGGTTCGCGCCGG
AAAAGGGCGAGGGGCGTTCAAAACGCATCGCTGAACAGAGTGCGGCGGAAGCCATGCTTTACCGCGAGGGTGTCTGGAAA
CGTGACGGTTCTGCTTGA

Upstream 100 bases:

>100_bases
AATATCATTTTCTTCTCCATTGCCGACAAGGCAAGCCCGCTTGAAATATGGAAATGGCCAACTGATGTCCGGTTCAACCG
GCTGTTTACCTGGGTCAGCG

Downstream 100 bases:

>100_bases
GGTAAAACCGGCGTTTTTTGTATCGAATTATACTATAGTCAAATGATTGCGACGGTGATCGGCTTGAAAGCGGCTCTGTT
GCAACGGGATGCTGTTGCTC

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNRTRPLPEIKMVSANKTASILEERTGHRFLNLKRLERALTHSSVQAPARANYERLEFLGDRVLGLTVAEMLFEAFPEAS
EGELSVRLNALVNAETCAAIADEIGLADLIHTGSDIKSLNDKRLLNVRADVVEALIATIYLDGGLEAARSFIQRYWKKRS
LETGAARRDAKTELQEWAHQQGNVHPVYAILSRSGPDHDPLFLVEVTVKGFAPEKGEGRSKRIAEQSAAEAMLYREGVWK
RDGSA

Sequences:

>Translated_245_residues
MNRTRPLPEIKMVSANKTASILEERTGHRFLNLKRLERALTHSSVQAPARANYERLEFLGDRVLGLTVAEMLFEAFPEAS
EGELSVRLNALVNAETCAAIADEIGLADLIHTGSDIKSLNDKRLLNVRADVVEALIATIYLDGGLEAARSFIQRYWKKRS
LETGAARRDAKTELQEWAHQQGNVHPVYAILSRSGPDHDPLFLVEVTVKGFAPEKGEGRSKRIAEQSAAEAMLYREGVWK
RDGSA
>Mature_245_residues
MNRTRPLPEIKMVSANKTASILEERTGHRFLNLKRLERALTHSSVQAPARANYERLEFLGDRVLGLTVAEMLFEAFPEAS
EGELSVRLNALVNAETCAAIADEIGLADLIHTGSDIKSLNDKRLLNVRADVVEALIATIYLDGGLEAARSFIQRYWKKRS
LETGAARRDAKTELQEWAHQQGNVHPVYAILSRSGPDHDPLFLVEVTVKGFAPEKGEGRSKRIAEQSAAEAMLYREGVWK
RDGSA

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain

Homologues:

Organism=Homo sapiens, GI155030234, Length=220, Percent_Identity=32.2727272727273, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI155030236, Length=220, Percent_Identity=32.2727272727273, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1788920, Length=205, Percent_Identity=33.6585365853659, Blast_Score=104, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17506883, Length=228, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193202651, Length=228, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17137682, Length=230, Percent_Identity=28.695652173913, Blast_Score=84, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNC_BRUA1 (B2SAD9)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001934643.1
- ProteinModelPortal:   B2SAD9
- SMR:   B2SAD9
- GeneID:   6327799
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I06380
- HOGENOM:   HBG744556
- OMA:   ALTHKSF
- ProtClustDB:   PRK12371
- GO:   GO:0005737
- HAMAP:   MF_00104
- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907
- Gene3D:   G3DSA:3.30.160.20
- Gene3D:   G3DSA:1.10.1520.10
- SMART:   SM00358
- SMART:   SM00535
- TIGRFAMs:   TIGR02191

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3; SSF69065 RNase_III

EC number: =3.1.26.3

Molecular weight: Translated: 27220; Mature: 27220

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50137 DS_RBD; PS00517 RNASE_3_1; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTRPLPEIKMVSANKTASILEERTGHRFLNLKRLERALTHSSVQAPARANYERLEFLG
CCCCCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHH
DRVLGLTVAEMLFEAFPEASEGELSVRLNALVNAETCAAIADEIGLADLIHTGSDIKSLN
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHCHHHHHHHHHHHHHHHHHHCCCHHHHCC
DKRLLNVRADVVEALIATIYLDGGLEAARSFIQRYWKKRSLETGAARRDAKTELQEWAHQ
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
QGNVHPVYAILSRSGPDHDPLFLVEVTVKGFAPEKGEGRSKRIAEQSAAEAMLYREGVWK
CCCCCHHHHEECCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
RDGSA
CCCCC
>Mature Secondary Structure
MNRTRPLPEIKMVSANKTASILEERTGHRFLNLKRLERALTHSSVQAPARANYERLEFLG
CCCCCCCCCEEEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHH
DRVLGLTVAEMLFEAFPEASEGELSVRLNALVNAETCAAIADEIGLADLIHTGSDIKSLN
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHCHHHHHHHHHHHHHHHHHHCCCHHHHCC
DKRLLNVRADVVEALIATIYLDGGLEAARSFIQRYWKKRSLETGAARRDAKTELQEWAHQ
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
QGNVHPVYAILSRSGPDHDPLFLVEVTVKGFAPEKGEGRSKRIAEQSAAEAMLYREGVWK
CCCCCHHHHEECCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
RDGSA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA