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The map label for this gene is lepB [H]

Identifier: 225852181

GI number: 225852181

Start: 671151

End: 671933

Strand: Direct

Name: lepB [H]

Synonym: BMEA_A0697

Alternate gene names: 225852181

Gene position: 671151-671933 (Clockwise)

Preceding gene: 225852180

Following gene: 225852182

Centisome position: 31.57

GC content: 56.58

Gene sequence:

>783_bases
ATGAGCGTGTCCAGCAAGAACGAAACTAAAAAATCCGGTGGCCTTGGCGAAACCATCAGCGTTATCGTGCAGGCGCTGCT
CCTGGCGCTGATTATCCGCACCCTTCTTTTCCAGCCTTTCAGCATTCCGTCCGGCTCCATGCGCCCCACGCTTCTGGAAG
GCGATTACCTGTTCGTGTCGAAATATGCCTATGGCTATTCGCGCTATTCGCTGCCTTTTGGCCTGGATCTCTTTTCGGGC
CGTATCTGGAGCGCGGAGCCGAAGCGCGGCGACGTTGTGGTGTTCAAACTGCCGAGCGATACGTCCGTCGATTACATCAA
GCGCGTGATCGGCCTGCCGGGCGACCGTGTGCAGATGCGCGGCGGCGTTCTCTATATCAACGACAAGCCGGTCAAGCGCG
AGCGCGTGGGCACGATCAACAATCCGGATGTGACGGAAGAGAACCGCCCCGTGGAAGTCTATCGTGAGACGCTGCCCAAT
GGCGTGACCTATGACACGCTGGAGCTTGCCCCGAATTCGATTGGCGATGACACCCGCGTCTTTGAAGTTCCTGCCGGTCA
TTATTTCATGATGGGCGACAATCGCGACAACTCCCTCGATAGCCGTTTCGGCGTGGGCTATGTGCCGTTTGAAAATCTCG
TCGGCCGCGCCAATATCATTTTCTTCTCCATTGCCGACAAGGCAAGCCCGCTTGAAATATGGAAATGGCCAACTGATGTC
CGGTTCAACCGGCTGTTTACCTGGGTCAGCGGTGAACCGCACACGGCCGTTACCGGAAATTAA

Upstream 100 bases:

>100_bases
GACAGATAACTCTTACTCATAATCGTGCGAGACAGTGGCGGCGTGATTGCCTCGCGCAGCCTTAGCCGTTATTAGATCGC
GTATAGGAAGCGGAGATACA

Downstream 100 bases:

>100_bases
GATGGTTTCGGCAAACAAGACTGCATCGATATTGGAAGAGCGCACAGGCCACCGTTTCCTCAATCTGAAACGGCTGGAAC
GCGCGCTCACCCATTCAAGC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSVSSKNETKKSGGLGETISVIVQALLLALIIRTLLFQPFSIPSGSMRPTLLEGDYLFVSKYAYGYSRYSLPFGLDLFSG
RIWSAEPKRGDVVVFKLPSDTSVDYIKRVIGLPGDRVQMRGGVLYINDKPVKRERVGTINNPDVTEENRPVEVYRETLPN
GVTYDTLELAPNSIGDDTRVFEVPAGHYFMMGDNRDNSLDSRFGVGYVPFENLVGRANIIFFSIADKASPLEIWKWPTDV
RFNRLFTWVSGEPHTAVTGN

Sequences:

>Translated_260_residues
MSVSSKNETKKSGGLGETISVIVQALLLALIIRTLLFQPFSIPSGSMRPTLLEGDYLFVSKYAYGYSRYSLPFGLDLFSG
RIWSAEPKRGDVVVFKLPSDTSVDYIKRVIGLPGDRVQMRGGVLYINDKPVKRERVGTINNPDVTEENRPVEVYRETLPN
GVTYDTLELAPNSIGDDTRVFEVPAGHYFMMGDNRDNSLDSRFGVGYVPFENLVGRANIIFFSIADKASPLEIWKWPTDV
RFNRLFTWVSGEPHTAVTGN
>Mature_259_residues
SVSSKNETKKSGGLGETISVIVQALLLALIIRTLLFQPFSIPSGSMRPTLLEGDYLFVSKYAYGYSRYSLPFGLDLFSGR
IWSAEPKRGDVVVFKLPSDTSVDYIKRVIGLPGDRVQMRGGVLYINDKPVKRERVGTINNPDVTEENRPVEVYRETLPNG
VTYDTLELAPNSIGDDTRVFEVPAGHYFMMGDNRDNSLDSRFGVGYVPFENLVGRANIIFFSIADKASPLEIWKWPTDVR
FNRLFTWVSGEPHTAVTGN

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=282, Percent_Identity=36.1702127659575, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 29084; Mature: 28953

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSSKNETKKSGGLGETISVIVQALLLALIIRTLLFQPFSIPSGSMRPTLLEGDYLFVS
CCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEEEEE
KYAYGYSRYSLPFGLDLFSGRIWSAEPKRGDVVVFKLPSDTSVDYIKRVIGLPGDRVQMR
EECCCCEEECCCCCCHHHCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEE
GGVLYINDKPVKRERVGTINNPDVTEENRPVEVYRETLPNGVTYDTLELAPNSIGDDTRV
CCEEEECCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEHEECCCCCCCCCEE
FEVPAGHYFMMGDNRDNSLDSRFGVGYVPFENLVGRANIIFFSIADKASPLEIWKWPTDV
EEECCCEEEEEECCCCCCCCHHCCCCCCCHHHHCCCCEEEEEEECCCCCCCEEEECCCCC
RFNRLFTWVSGEPHTAVTGN
EEEEEEEEECCCCCEEECCC
>Mature Secondary Structure 
SVSSKNETKKSGGLGETISVIVQALLLALIIRTLLFQPFSIPSGSMRPTLLEGDYLFVS
CCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCEEEEE
KYAYGYSRYSLPFGLDLFSGRIWSAEPKRGDVVVFKLPSDTSVDYIKRVIGLPGDRVQMR
EECCCCEEECCCCCCHHHCCEEECCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCEEEEE
GGVLYINDKPVKRERVGTINNPDVTEENRPVEVYRETLPNGVTYDTLELAPNSIGDDTRV
CCEEEECCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEHEECCCCCCCCCEE
FEVPAGHYFMMGDNRDNSLDSRFGVGYVPFENLVGRANIIFFSIADKASPLEIWKWPTDV
EEECCCEEEEEECCCCCCCCHHCCCCCCCHHHHCCCCEEEEEEECCCCCCCEEEECCCCC
RFNRLFTWVSGEPHTAVTGN
EEEEEEEEECCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA