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The map label for this gene is acpS

Identifier: 225852180

GI number: 225852180

Start: 670636

End: 671040

Strand: Direct

Name: acpS

Synonym: BMEA_A0696

Alternate gene names: 225852180

Gene position: 670636-671040 (Clockwise)

Preceding gene: 225852179

Following gene: 225852181

Centisome position: 31.55

GC content: 54.57

Gene sequence:

>405_bases
ATGATCGTTGGAATTGGAAGCGATCTCATTGATATTCGCCGGGTCGAAAAAACGCTGGAACGGCACGGCAGCCGTTTTCG
GGACCGGGTTTTTACCGAAATCGAGCAGAGGAAGTCGGAGGGGCGCAAGCAGCGCGCCGCGTCCTATGCAAAGCGTTTCG
CGGCGAAGGAAGCCTGCGCCAAGGCTCTTGGCACAGGCATTGCAGAGGGCGTTTTCTGGCGTGATATGGGCGTGGTGAAT
ACGCCTTCCGGCAAGCCGACCATGCATCTTACCGGCGGTGCGGCGAAGCAGCTTCAAAAGCTTCTTCCAGCCGGAACCAA
TGCTGCAATACATCTGACAATTACCGATGATTTTCCTTTGGCGCAGGCATTCGTCATTATCGAAGCCTTGCCAGTTTTAG
AATAA

Upstream 100 bases:

>100_bases
ATTTCGTAACCCGCTACGCCGTTTCCGTCTTCCGCCGCCGCCGTCTGGAGCGTCTGGCCGAAAAGCATCGCCTGCATCGC
CAGCGGGAGTTGCAGAAGGC

Downstream 100 bases:

>100_bases
TTGCGACTGTGACAGATAACTCTTACTCATAATCGTGCGAGACAGTGGCGGCGTGATTGCCTCGCGCAGCCTTAGCCGTT
ATTAGATCGCGTATAGGAAG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MIVGIGSDLIDIRRVEKTLERHGSRFRDRVFTEIEQRKSEGRKQRAASYAKRFAAKEACAKALGTGIAEGVFWRDMGVVN
TPSGKPTMHLTGGAAKQLQKLLPAGTNAAIHLTITDDFPLAQAFVIIEALPVLE

Sequences:

>Translated_134_residues
MIVGIGSDLIDIRRVEKTLERHGSRFRDRVFTEIEQRKSEGRKQRAASYAKRFAAKEACAKALGTGIAEGVFWRDMGVVN
TPSGKPTMHLTGGAAKQLQKLLPAGTNAAIHLTITDDFPLAQAFVIIEALPVLE
>Mature_134_residues
MIVGIGSDLIDIRRVEKTLERHGSRFRDRVFTEIEQRKSEGRKQRAASYAKRFAAKEACAKALGTGIAEGVFWRDMGVVN
TPSGKPTMHLTGGAAKQLQKLLPAGTNAAIHLTITDDFPLAQAFVIIEALPVLE

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=39.84375, Blast_Score=83, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_BRUA1 (B2SAD7)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001934641.1
- ProteinModelPortal:   B2SAD7
- SMR:   B2SAD7
- GeneID:   6327797
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I06360
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14645; Mature: 14645

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGIGSDLIDIRRVEKTLERHGSRFRDRVFTEIEQRKSEGRKQRAASYAKRFAAKEACA
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGIAEGVFWRDMGVVNTPSGKPTMHLTGGAAKQLQKLLPAGTNAAIHLTITDDFPL
HHHHHHHHHHHHHHCCCCEECCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCH
AQAFVIIEALPVLE
HHHHHHHHHHHCCC
>Mature Secondary Structure
MIVGIGSDLIDIRRVEKTLERHGSRFRDRVFTEIEQRKSEGRKQRAASYAKRFAAKEACA
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGIAEGVFWRDMGVVNTPSGKPTMHLTGGAAKQLQKLLPAGTNAAIHLTITDDFPL
HHHHHHHHHHHHHHCCCCEECCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEEECCCCCH
AQAFVIIEALPVLE
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA