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The map label for this gene is rcsC [C]

Identifier: 225852106

GI number: 225852106

Start: 590043

End: 591872

Strand: Direct

Name: rcsC [C]

Synonym: BMEA_A0616

Alternate gene names: 225852106

Gene position: 590043-591872 (Clockwise)

Preceding gene: 225852103

Following gene: 225852107

Centisome position: 27.76

GC content: 59.29

Gene sequence:

>1830_bases
TTGAACGTCATTCATTTGAAAGCAGCGCAGATCGTTCGCAACAGCCTGCATGGGCTGGCCTGCTTTCACGACCGTTTTTG
CCGGCGCTGGGTCGCAACGCCCGATGCGGCGTCGATACGCGTCATCGGTGCGGTTTTCACCTTGCCCTTCCTGCTTTGTG
CCGCTGTTGCGGCTTCGGGCGTCGCCGCTGGCCTGACGGATTTTGCTATTCTCGCTGGCAGTTTTACAGGCGTGGCGATG
ATTTTCTGTGCCCTGTCGCTCATGGGCCTGCGCGCGGGAATTCTGGGTGCGCTCAATTTTGCAGCCTATGGCGCGGGGCT
TGCCACAATTGGCGCTTTCTCGAACGGCAATGCGGCGCTGTGGCTGATGGCTGCGGGCCTGCCGCTTGAAATCTGGTTTG
CAAGCCGCAAGCCCGGCAGCACCATCGCAGGCTCCCTTGCAGCCATGGCGATCCTTGCTTTCCTCGCGGTGAAAACCGGC
GGGACTATATCGGGCGGCTCGCTCATTTCTGGTGCGATATTGTTGCTTTACGCGGCAAGTCTTGTTCTGCGGGGCGTTGC
CGTGGCGCGCAAGCCCGTGCAAATTTCTGTCGCCGCGCCACAGGTTGCCGTCGCTGCTGGCGATACGCAGTTCGGCCTCG
ATATTGAAGGTATTGTTTCTTCGGTCGATGGCGAGACGGCAAAGCTGCTTGGTGTGCAGCCGAAAATGCTGGAAGGCACG
GCGCTGATCGACCGCGTACATGTGGCTGACCGCGTACAGTATCTTTCGCTTCTGGCCGATCTTCGCGCAGGCATGGCCAC
CCGCAAGGTGGATGTGCGTCTGCGTTCAATCGAAAATGGCAATCCGGTTTTTCGCGCCTATCGCTTTGAGGGGGCGGGCA
GCGACCGGGCCATTACCCTGATTGGCCGTTCGCTGGAAGGCGAACAGAAGCTTCTCGATGAAATCGCGATGCTGAAAGCG
GAACTGGAATCCGAACGAATCGGCAAGGGCCGCCTTCTGGCTACCGTTAGCCACGAGTTGCGCACGCCGCTCAATTCCAT
CATCGGTTTTTCCGACATGCTGACGCATGAAATCGGTGGCAAGCTCGCCAGTGACAGGCAGCGTGAATATGCGGGCCTCA
TCCATCAGTCCGGCCATTATCTGCTTGAGCTGGTCAATGCTGTCCTCGACAATTCGCGGCTGGAAACCGGCACTTATTCC
ATCGCGCCGCAGAGCTTCGTCTTCCGCGATGCCGTAGAAATGTGCACGGCGGTCATGCTGCCGCAGGCAGAAAAGAAGGG
CGTTGACTTCTGTCACCGGGTTGGCAATGGTGTGGGTGAACTCGTGGCTGATCGCCGCGCGGTGCAGCAGATTCTGCTCA
ACCTTGCCACCAATGCGGTGAAGTTTACCCAATCGGGCGGTTGTGTCACCATTGATGCCGCGCGCGTCATGGCAGATGGG
TGCCCGATGCTGGAATTCAGCGTTTCGGATACCGGCATTGGCATCGAGCCGGAAGACCTCCAGCGGATCGGAACGCCTTT
TGTGCGCGCCGGCAACAGCTATACGCAGGCGCAGGAAGGAAGCGGTCTCGGTCTTTCGGTCGTCAAGGGATTGGTGGAAC
GGCATCAAGGCTCGATGCAGCTCAAGAGCCGCCCCGGCGAAGGCACGGTCGTCATGATCCGCCTGCCGCTGGCTGGCCCG
CAATATCGCGCAGGAGAAGAACAACAGGAACTTGGCACGGTGATCGATATGTACCGTCACCAGGGAGAAAGGCGTAATGA
CTGGCAGAAAGACGAAATCCGGGACCAAAGCCCAGAGCAGCCACATGCGCAAACCCGCAAAACGGCGTAG

Upstream 100 bases:

>100_bases
GTTTCTTTAAAGCCTCATCTGCAATCTGGAGCCAACCGGAGGGCTGTTTTTCAAAATCGGCTTTCATGGGCAAGAATATT
GCGAGAGTGAGTAGGACACG

Downstream 100 bases:

>100_bases
CCTCGCAGCACGGCTCCTTCATTTCTTTTTCACGTCGGCTTCGGTGCTTGCGATAGCTGCCGGGGATTTTGTCGTGCGCA
ATCCTGTCCTGACCGGGGGT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MNVIHLKAAQIVRNSLHGLACFHDRFCRRWVATPDAASIRVIGAVFTLPFLLCAAVAASGVAAGLTDFAILAGSFTGVAM
IFCALSLMGLRAGILGALNFAAYGAGLATIGAFSNGNAALWLMAAGLPLEIWFASRKPGSTIAGSLAAMAILAFLAVKTG
GTISGGSLISGAILLLYAASLVLRGVAVARKPVQISVAAPQVAVAAGDTQFGLDIEGIVSSVDGETAKLLGVQPKMLEGT
ALIDRVHVADRVQYLSLLADLRAGMATRKVDVRLRSIENGNPVFRAYRFEGAGSDRAITLIGRSLEGEQKLLDEIAMLKA
ELESERIGKGRLLATVSHELRTPLNSIIGFSDMLTHEIGGKLASDRQREYAGLIHQSGHYLLELVNAVLDNSRLETGTYS
IAPQSFVFRDAVEMCTAVMLPQAEKKGVDFCHRVGNGVGELVADRRAVQQILLNLATNAVKFTQSGGCVTIDAARVMADG
CPMLEFSVSDTGIGIEPEDLQRIGTPFVRAGNSYTQAQEGSGLGLSVVKGLVERHQGSMQLKSRPGEGTVVMIRLPLAGP
QYRAGEEQQELGTVIDMYRHQGERRNDWQKDEIRDQSPEQPHAQTRKTA

Sequences:

>Translated_609_residues
MNVIHLKAAQIVRNSLHGLACFHDRFCRRWVATPDAASIRVIGAVFTLPFLLCAAVAASGVAAGLTDFAILAGSFTGVAM
IFCALSLMGLRAGILGALNFAAYGAGLATIGAFSNGNAALWLMAAGLPLEIWFASRKPGSTIAGSLAAMAILAFLAVKTG
GTISGGSLISGAILLLYAASLVLRGVAVARKPVQISVAAPQVAVAAGDTQFGLDIEGIVSSVDGETAKLLGVQPKMLEGT
ALIDRVHVADRVQYLSLLADLRAGMATRKVDVRLRSIENGNPVFRAYRFEGAGSDRAITLIGRSLEGEQKLLDEIAMLKA
ELESERIGKGRLLATVSHELRTPLNSIIGFSDMLTHEIGGKLASDRQREYAGLIHQSGHYLLELVNAVLDNSRLETGTYS
IAPQSFVFRDAVEMCTAVMLPQAEKKGVDFCHRVGNGVGELVADRRAVQQILLNLATNAVKFTQSGGCVTIDAARVMADG
CPMLEFSVSDTGIGIEPEDLQRIGTPFVRAGNSYTQAQEGSGLGLSVVKGLVERHQGSMQLKSRPGEGTVVMIRLPLAGP
QYRAGEEQQELGTVIDMYRHQGERRNDWQKDEIRDQSPEQPHAQTRKTA
>Mature_609_residues
MNVIHLKAAQIVRNSLHGLACFHDRFCRRWVATPDAASIRVIGAVFTLPFLLCAAVAASGVAAGLTDFAILAGSFTGVAM
IFCALSLMGLRAGILGALNFAAYGAGLATIGAFSNGNAALWLMAAGLPLEIWFASRKPGSTIAGSLAAMAILAFLAVKTG
GTISGGSLISGAILLLYAASLVLRGVAVARKPVQISVAAPQVAVAAGDTQFGLDIEGIVSSVDGETAKLLGVQPKMLEGT
ALIDRVHVADRVQYLSLLADLRAGMATRKVDVRLRSIENGNPVFRAYRFEGAGSDRAITLIGRSLEGEQKLLDEIAMLKA
ELESERIGKGRLLATVSHELRTPLNSIIGFSDMLTHEIGGKLASDRQREYAGLIHQSGHYLLELVNAVLDNSRLETGTYS
IAPQSFVFRDAVEMCTAVMLPQAEKKGVDFCHRVGNGVGELVADRRAVQQILLNLATNAVKFTQSGGCVTIDAARVMADG
CPMLEFSVSDTGIGIEPEDLQRIGTPFVRAGNSYTQAQEGSGLGLSVVKGLVERHQGSMQLKSRPGEGTVVMIRLPLAGP
QYRAGEEQQELGTVIDMYRHQGERRNDWQKDEIRDQSPEQPHAQTRKTA

Specific function: Member Of The Two-Component Regulatory System rcsC/rcsB Involved In The Regulation Of The Expression Of Genes Involved In Colanic Acid Capsule Synthesis. rcsC Probably Functions As A Membrane-Associated Protein Kinase That Phosphorylates rcsB In Response

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAC (PAS-associated C-terminal) domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=237, Percent_Identity=35.4430379746835, Blast_Score=129, Evalue=8e-31,
Organism=Escherichia coli, GI1789149, Length=273, Percent_Identity=31.5018315018315, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1788713, Length=278, Percent_Identity=30.2158273381295, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=32.0512820512821, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI87081816, Length=252, Percent_Identity=30.952380952381, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790436, Length=264, Percent_Identity=26.8939393939394, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=29.2576419213974, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=28.8702928870293, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=26.890756302521, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=241, Percent_Identity=28.2157676348548, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1788393, Length=250, Percent_Identity=26.8, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786783, Length=255, Percent_Identity=25.0980392156863, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64814; Mature: 64814

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIHLKAAQIVRNSLHGLACFHDRFCRRWVATPDAASIRVIGAVFTLPFLLCAAVAASG
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VAAGLTDFAILAGSFTGVAMIFCALSLMGLRAGILGALNFAAYGAGLATIGAFSNGNAAL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEE
WLMAAGLPLEIWFASRKPGSTIAGSLAAMAILAFLAVKTGGTISGGSLISGAILLLYAAS
EEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LVLRGVAVARKPVQISVAAPQVAVAAGDTQFGLDIEGIVSSVDGETAKLLGVQPKMLEGT
HHHHHHHHHCCCEEEEEECCEEEEEECCCCCCCCHHHHHHHCCCCHHHHCCCCCHHHCCH
ALIDRVHVADRVQYLSLLADLRAGMATRKVDVRLRSIENGNPVFRAYRFEGAGSDRAITL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEECCCCCCEEEEEEECCCCCCCEEEE
IGRSLEGEQKLLDEIAMLKAELESERIGKGRLLATVSHELRTPLNSIIGFSDMLTHEIGG
EECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCHHHHHCHHHHHHHHHCC
KLASDRQREYAGLIHQSGHYLLELVNAVLDNSRLETGTYSIAPQSFVFRDAVEMCTAVML
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHC
PQAEKKGVDFCHRVGNGVGELVADRRAVQQILLNLATNAVKFTQSGGCVTIDAARVMADG
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEHHHHHHCC
CPMLEFSVSDTGIGIEPEDLQRIGTPFVRAGNSYTQAQEGSGLGLSVVKGLVERHQGSMQ
CCEEEEEECCCCCCCCHHHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEE
LKSRPGEGTVVMIRLPLAGPQYRAGEEQQELGTVIDMYRHQGERRNDWQKDEIRDQSPEQ
ECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCC
PHAQTRKTA
CCCCCCCCC
>Mature Secondary Structure
MNVIHLKAAQIVRNSLHGLACFHDRFCRRWVATPDAASIRVIGAVFTLPFLLCAAVAASG
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VAAGLTDFAILAGSFTGVAMIFCALSLMGLRAGILGALNFAAYGAGLATIGAFSNGNAAL
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEE
WLMAAGLPLEIWFASRKPGSTIAGSLAAMAILAFLAVKTGGTISGGSLISGAILLLYAAS
EEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
LVLRGVAVARKPVQISVAAPQVAVAAGDTQFGLDIEGIVSSVDGETAKLLGVQPKMLEGT
HHHHHHHHHCCCEEEEEECCEEEEEECCCCCCCCHHHHHHHCCCCHHHHCCCCCHHHCCH
ALIDRVHVADRVQYLSLLADLRAGMATRKVDVRLRSIENGNPVFRAYRFEGAGSDRAITL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEEECCCCCCEEEEEEECCCCCCCEEEE
IGRSLEGEQKLLDEIAMLKAELESERIGKGRLLATVSHELRTPLNSIIGFSDMLTHEIGG
EECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHCCHHHHHCHHHHHHHHHCC
KLASDRQREYAGLIHQSGHYLLELVNAVLDNSRLETGTYSIAPQSFVFRDAVEMCTAVML
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHC
PQAEKKGVDFCHRVGNGVGELVADRRAVQQILLNLATNAVKFTQSGGCVTIDAARVMADG
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEHHHHHHCC
CPMLEFSVSDTGIGIEPEDLQRIGTPFVRAGNSYTQAQEGSGLGLSVVKGLVERHQGSMQ
CCEEEEEECCCCCCCCHHHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCEE
LKSRPGEGTVVMIRLPLAGPQYRAGEEQQELGTVIDMYRHQGERRNDWQKDEIRDQSPEQ
ECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCC
PHAQTRKTA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430; 7756693 [H]