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The map label for this gene is ubiA [H]

Identifier: 225851951

GI number: 225851951

Start: 440880

End: 441881

Strand: Direct

Name: ubiA [H]

Synonym: BMEA_A0446

Alternate gene names: 225851951

Gene position: 440880-441881 (Clockwise)

Preceding gene: 225851949

Following gene: 225851953

Centisome position: 20.74

GC content: 61.48

Gene sequence:

>1002_bases
ATGCAGCAACCACAGGCAAATTCCGATATCCAGTCGCGCGCGGCGCGCGGGCGGGTGAAGGATGCGCCCTCCGGCCATTG
GGTCTATCGCGTCCTGCCGCAATGGCTCTGGCCCTATGCGCAGCTTGCCCGCTGGGACCGTCCGATCGGCTGGCAGCTTT
TGCTCTGGCCCTGCTGGTGGTCCACCGCACTTGTGGCGGGTGCTGGCGCAAAGGCTGGCGACGGCGCATGGTCCGTGCTG
CCGTCTTTCTGGCATCTTTTCCTGTTCCTCGTCGGCGCCATCGCCATGCGCGGCGCAGGCTGCACCTATAATGATCTGGT
CGATCAGGAGATCGACGACAAGGTGGACCGTACGCGCTCGCGCCCGTTGCCTTCGGGGCAGGTGACGCGCAAACAGGCCA
AGCTGTTTGTGGTTTTGCAGGCGCTGGTCGGCCTTGCTGTCGTGCTGCAATTCAACTGGTTTTCCGTCGGGCTCGGCATT
TTCTCGCTTCTGATCGTCGCCGCCTATCCCTTCATGAAGCGCATCACCGACTGGCCGCAATTCGTGCTGGGGCTTGCCTT
CTCATGGGGTGCATTGATGGGTTGGGCTGCAACGGAAGGCTCACTCAGCCTTCCGCCGGTGCTGCTCTATATCGGTGCGA
TCCTGTGGACCATCGGCTATGACACGATCTACGCCCATCAGGATAAGGAAGACGATGCGCTGGTCGGTGTACGCTCCACC
GCGCGGCTTTTCGGCAAGCACACGAAAACGGCGCTCATGGTGCTTTATGGCGGGGCAATCGGCTTTTTCGCGGCAGCTTT
CGCCGTGGCCCAGGTGCCCATGCCCGCCCTCGCCGGCCTGCTGGCGGCTGGCGCGCATCTTTATCGCCAGATACTCGTGC
TCGATATCGACAATCCCGACCAGTGCCTGCGGCTCTTCAAGTCGAACAATATTGTCGGCTGGCTGATCTTTCTTGGGCTT
GTATTCGGAACCCTCTGGGTTGCGGTAAAGCCGCTTGTATGA

Upstream 100 bases:

>100_bases
TTCCGGCTGTCTATTGCTCCCGCTTGTCGAGAGCAATACCAAAGGGTTAGATTTTGGCCAATAATGCCGGAATTGACGGT
TTTTTTGAACGGATTGGGCC

Downstream 100 bases:

>100_bases
AGGAAGGCCACCGTTTCGGGTGGCCTTTGCGTTGTTAGATCAGGGATAAAGCCTGTCCTTGTTCCAGTCGCCTTCCGGCG
TTGGCCGCGTGAAAAGCACA

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MQQPQANSDIQSRAARGRVKDAPSGHWVYRVLPQWLWPYAQLARWDRPIGWQLLLWPCWWSTALVAGAGAKAGDGAWSVL
PSFWHLFLFLVGAIAMRGAGCTYNDLVDQEIDDKVDRTRSRPLPSGQVTRKQAKLFVVLQALVGLAVVLQFNWFSVGLGI
FSLLIVAAYPFMKRITDWPQFVLGLAFSWGALMGWAATEGSLSLPPVLLYIGAILWTIGYDTIYAHQDKEDDALVGVRST
ARLFGKHTKTALMVLYGGAIGFFAAAFAVAQVPMPALAGLLAAGAHLYRQILVLDIDNPDQCLRLFKSNNIVGWLIFLGL
VFGTLWVAVKPLV

Sequences:

>Translated_333_residues
MQQPQANSDIQSRAARGRVKDAPSGHWVYRVLPQWLWPYAQLARWDRPIGWQLLLWPCWWSTALVAGAGAKAGDGAWSVL
PSFWHLFLFLVGAIAMRGAGCTYNDLVDQEIDDKVDRTRSRPLPSGQVTRKQAKLFVVLQALVGLAVVLQFNWFSVGLGI
FSLLIVAAYPFMKRITDWPQFVLGLAFSWGALMGWAATEGSLSLPPVLLYIGAILWTIGYDTIYAHQDKEDDALVGVRST
ARLFGKHTKTALMVLYGGAIGFFAAAFAVAQVPMPALAGLLAAGAHLYRQILVLDIDNPDQCLRLFKSNNIVGWLIFLGL
VFGTLWVAVKPLV
>Mature_333_residues
MQQPQANSDIQSRAARGRVKDAPSGHWVYRVLPQWLWPYAQLARWDRPIGWQLLLWPCWWSTALVAGAGAKAGDGAWSVL
PSFWHLFLFLVGAIAMRGAGCTYNDLVDQEIDDKVDRTRSRPLPSGQVTRKQAKLFVVLQALVGLAVVLQFNWFSVGLGI
FSLLIVAAYPFMKRITDWPQFVLGLAFSWGALMGWAATEGSLSLPPVLLYIGAILWTIGYDTIYAHQDKEDDALVGVRST
ARLFGKHTKTALMVLYGGAIGFFAAAFAVAQVPMPALAGLLAAGAHLYRQILVLDIDNPDQCLRLFKSNNIVGWLIFLGL
VFGTLWVAVKPLV

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=295, Percent_Identity=45.7627118644068, Blast_Score=246, Evalue=3e-65,
Organism=Escherichia coli, GI1790473, Length=283, Percent_Identity=38.86925795053, Blast_Score=176, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17553718, Length=294, Percent_Identity=45.9183673469388, Blast_Score=228, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI32565247, Length=307, Percent_Identity=42.0195439739414, Blast_Score=208, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17553720, Length=351, Percent_Identity=35.042735042735, Blast_Score=170, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI32565245, Length=162, Percent_Identity=46.2962962962963, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI32565243, Length=161, Percent_Identity=45.9627329192547, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324370, Length=295, Percent_Identity=38.9830508474576, Blast_Score=179, Evalue=6e-46,
Organism=Drosophila melanogaster, GI21355567, Length=290, Percent_Identity=52.7586206896552, Blast_Score=273, Evalue=1e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 36739; Mature: 36739

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQPQANSDIQSRAARGRVKDAPSGHWVYRVLPQWLWPYAQLARWDRPIGWQLLLWPCWW
CCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHH
STALVAGAGAKAGDGAWSVLPSFWHLFLFLVGAIAMRGAGCTYNDLVDQEIDDKVDRTRS
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
RPLPSGQVTRKQAKLFVVLQALVGLAVVLQFNWFSVGLGIFSLLIVAAYPFMKRITDWPQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLGLAFSWGALMGWAATEGSLSLPPVLLYIGAILWTIGYDTIYAHQDKEDDALVGVRST
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHEEECCCCCCCHHEEHHHH
ARLFGKHTKTALMVLYGGAIGFFAAAFAVAQVPMPALAGLLAAGAHLYRQILVLDIDNPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEECCCHH
QCLRLFKSNNIVGWLIFLGLVFGTLWVAVKPLV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQQPQANSDIQSRAARGRVKDAPSGHWVYRVLPQWLWPYAQLARWDRPIGWQLLLWPCWW
CCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHH
STALVAGAGAKAGDGAWSVLPSFWHLFLFLVGAIAMRGAGCTYNDLVDQEIDDKVDRTRS
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
RPLPSGQVTRKQAKLFVVLQALVGLAVVLQFNWFSVGLGIFSLLIVAAYPFMKRITDWPQ
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVLGLAFSWGALMGWAATEGSLSLPPVLLYIGAILWTIGYDTIYAHQDKEDDALVGVRST
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHEEECCCCCCCHHEEHHHH
ARLFGKHTKTALMVLYGGAIGFFAAAFAVAQVPMPALAGLLAAGAHLYRQILVLDIDNPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEECCCHH
QCLRLFKSNNIVGWLIFLGLVFGTLWVAVKPLV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA