BacMap

Definition	Brucella melitensis ATCC 23457 chromosome chromosome I, complete sequence.
Accession	NC_012441
Length	2,125,701

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The map label for this gene is cbpA [H]

Identifier: 225851953

GI number: 225851953

Start: 443420

End: 444361

Strand: Direct

Name: cbpA [H]

Synonym: BMEA_A0449

Alternate gene names: 225851953

Gene position: 443420-444361 (Clockwise)

Preceding gene: 225851951

Following gene: 225851955

Centisome position: 20.86

GC content: 59.98

Gene sequence:

>942_bases
ATGCGCGATCCCTATAGCGTGCTGGGCGTCGCCAAAACGGCGAAGCCCGAAGAAATAAAATCGGCCTTTCGCAAGCTGGC
CAAGAAGCACCACCCGGATCAGAATCAGGACGATCCGAAGGCGCAGGAGCGATTTGCGGAAGTGAATCAGGCCTATGAAA
TCATAGGCGACAAGGACAAGCGCGCCCAGTTCGACCGTGGCGAAATCGATGTCGAAGGCAAGCCGGTATTTCAGGGATTT
GCCGGCGGACAGGGGTTTGGCGGCGCGCATGGCGATCCTTTCGCGGGCTTCCGCCAGGGCGGCGGCAACAGTCATTTTGA
GTTCCGGGGCGGTCCCGGCGGATTTCAGGGTGGCGGCTTTGGCGGTGCGGAAGATATTCTGAACGATCTTTTCGGCGATG
CTTTTGGCGGCGGTCGCTCTGGCGCGCGCCAGCGCGGCCCGTCCAAGGGGGCGGACCTGTCTGCATCCATTGATATTTCG
CTTTCGCAGGCCGTGGGCGCGGAAAAGGTCGAGGCTATCTTTCCAAACGGCAAGCATCTGAAAATAAAACTGCCGAAATT
CGTCGAGGATGGCCAGACCATTCGCCTCAAGGGGCAGGGTGAACCGCTGATGGGCGGTACGCCGGGGGACGCGCTGGTGA
CGATCCGCTTCAAGCCGCATTCGCGTTTCCGCTTGGAAGGCCGCGACGTTCATGTCGACCTTCCGGTCAGCATTGACGAT
GCGGTTCTGGGCGGCAAGCAGGAAGTGGAAACGCTTGATGGGCGCATTTCGGTGAAGATTCCCGCATGGTCCAGTTCCGA
CCGCGTATTGCGCCTGAAGGAAAAGGGCCTTCCCTTGAAAGCGGGCGGCAGGGGCGACCTCTATGTCCATGTCCGCATCA
TGCTGCCGGAGGGCGGCGACAAGGAGCTTGAAGACTTCCTGCAAAAACGCAGGGTTGTGTGA

Upstream 100 bases:

>100_bases
CCGTGTGAGGCTGGAACTTTTGCGGCTGTATACGCATATTAGCTGTGAAAACGAGTCTATCCATTGGCTTTACAGCCTTT
TTTCCTGAAAGAGGAACTAT

Downstream 100 bases:

>100_bases
GCTTCAATCGGTTGAAGCGAAGGTGTTGTCACTTTGCGCCAGTAACGTGACAATACCAGCCTTTTTATCCGCAATTGCTT
GAAGGATAGCGAAGCCTGTG

Product: chaperone protein DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MRDPYSVLGVAKTAKPEEIKSAFRKLAKKHHPDQNQDDPKAQERFAEVNQAYEIIGDKDKRAQFDRGEIDVEGKPVFQGF
AGGQGFGGAHGDPFAGFRQGGGNSHFEFRGGPGGFQGGGFGGAEDILNDLFGDAFGGGRSGARQRGPSKGADLSASIDIS
LSQAVGAEKVEAIFPNGKHLKIKLPKFVEDGQTIRLKGQGEPLMGGTPGDALVTIRFKPHSRFRLEGRDVHVDLPVSIDD
AVLGGKQEVETLDGRISVKIPAWSSSDRVLRLKEKGLPLKAGGRGDLYVHVRIMLPEGGDKELEDFLQKRRVV

Sequences:

>Translated_313_residues
MRDPYSVLGVAKTAKPEEIKSAFRKLAKKHHPDQNQDDPKAQERFAEVNQAYEIIGDKDKRAQFDRGEIDVEGKPVFQGF
AGGQGFGGAHGDPFAGFRQGGGNSHFEFRGGPGGFQGGGFGGAEDILNDLFGDAFGGGRSGARQRGPSKGADLSASIDIS
LSQAVGAEKVEAIFPNGKHLKIKLPKFVEDGQTIRLKGQGEPLMGGTPGDALVTIRFKPHSRFRLEGRDVHVDLPVSIDD
AVLGGKQEVETLDGRISVKIPAWSSSDRVLRLKEKGLPLKAGGRGDLYVHVRIMLPEGGDKELEDFLQKRRVV
>Mature_313_residues
MRDPYSVLGVAKTAKPEEIKSAFRKLAKKHHPDQNQDDPKAQERFAEVNQAYEIIGDKDKRAQFDRGEIDVEGKPVFQGF
AGGQGFGGAHGDPFAGFRQGGGNSHFEFRGGPGGFQGGGFGGAEDILNDLFGDAFGGGRSGARQRGPSKGADLSASIDIS
LSQAVGAEKVEAIFPNGKHLKIKLPKFVEDGQTIRLKGQGEPLMGGTPGDALVTIRFKPHSRFRLEGRDVHVDLPVSIDD
AVLGGKQEVETLDGRISVKIPAWSSSDRVLRLKEKGLPLKAGGRGDLYVHVRIMLPEGGDKELEDFLQKRRVV

Specific function: DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adapt

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm, nucleoid [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI5453690, Length=323, Percent_Identity=30.9597523219814, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI194328760, Length=346, Percent_Identity=27.7456647398844, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI194328758, Length=346, Percent_Identity=27.7456647398844, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI6631085, Length=338, Percent_Identity=30.4733727810651, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI56549115, Length=343, Percent_Identity=26.530612244898, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI201862518, Length=343, Percent_Identity=26.530612244898, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI201862587, Length=343, Percent_Identity=27.1137026239067, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI7706495, Length=274, Percent_Identity=28.8321167883212, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4504511, Length=339, Percent_Identity=29.4985250737463, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI39204547, Length=312, Percent_Identity=27.5641025641026, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI205360838, Length=110, Percent_Identity=39.0909090909091, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI205360840, Length=110, Percent_Identity=39.0909090909091, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI29126218, Length=62, Percent_Identity=53.2258064516129, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI24308127, Length=65, Percent_Identity=49.2307692307692, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI56687498, Length=64, Percent_Identity=46.875, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI23503241, Length=119, Percent_Identity=37.8151260504202, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI45504382, Length=62, Percent_Identity=46.7741935483871, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4885495, Length=67, Percent_Identity=47.7611940298507, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI47777312, Length=135, Percent_Identity=39.2592592592593, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI17388799, Length=67, Percent_Identity=49.2537313432836, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787235, Length=327, Percent_Identity=31.1926605504587, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786197, Length=297, Percent_Identity=30.3030303030303, Blast_Score=91, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI212645553, Length=299, Percent_Identity=32.7759197324415, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17534355, Length=320, Percent_Identity=32.5, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17554644, Length=91, Percent_Identity=45.0549450549451, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115532378, Length=85, Percent_Identity=42.3529411764706, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI86563276, Length=106, Percent_Identity=41.5094339622642, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554900, Length=166, Percent_Identity=29.5180722891566, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532476, Length=64, Percent_Identity=43.75, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322194, Length=62, Percent_Identity=48.3870967741936, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323813, Length=152, Percent_Identity=37.5, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323119, Length=64, Percent_Identity=48.4375, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323870, Length=65, Percent_Identity=41.5384615384615, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24658562, Length=332, Percent_Identity=33.1325301204819, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24658555, Length=332, Percent_Identity=33.1325301204819, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI19920464, Length=312, Percent_Identity=28.525641025641, Blast_Score=108, Evalue=7e-24,
Organism=Drosophila melanogaster, GI85726398, Length=343, Percent_Identity=30.3206997084548, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18858081, Length=344, Percent_Identity=29.0697674418605, Blast_Score=94, Evalue=9e-20,
Organism=Drosophila melanogaster, GI45552811, Length=348, Percent_Identity=27.8735632183908, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45549272, Length=64, Percent_Identity=50, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI45552813, Length=64, Percent_Identity=50, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24646562, Length=63, Percent_Identity=49.2063492063492, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646560, Length=63, Percent_Identity=49.2063492063492, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646558, Length=63, Percent_Identity=49.2063492063492, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24646556, Length=63, Percent_Identity=49.2063492063492, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357547, Length=63, Percent_Identity=49.2063492063492, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355911, Length=110, Percent_Identity=39.0909090909091, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737735, Length=62, Percent_Identity=46.7741935483871, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24668523, Length=62, Percent_Identity=46.7741935483871, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574723, Length=62, Percent_Identity=46.7741935483871, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654066, Length=66, Percent_Identity=45.4545454545455, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24654070, Length=66, Percent_Identity=45.4545454545455, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24654068, Length=66, Percent_Identity=45.4545454545455, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24654072, Length=66, Percent_Identity=45.4545454545455, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C [H]

EC number: NA

Molecular weight: Translated: 33749; Mature: 33749

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDPYSVLGVAKTAKPEEIKSAFRKLAKKHHPDQNQDDPKAQERFAEVNQAYEIIGDKDK
CCCCHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHH
RAQFDRGEIDVEGKPVFQGFAGGQGFGGAHGDPFAGFRQGGGNSHFEFRGGPGGFQGGGF
CCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCHHHCCCCCCCEEECCCCCCCCCCCC
GGAEDILNDLFGDAFGGGRSGARQRGPSKGADLSASIDISLSQAVGAEKVEAIFPNGKHL
CCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCEEEEEEEEHHHCCCHHHEEECCCCCEE
KIKLPKFVEDGQTIRLKGQGEPLMGGTPGDALVTIRFKPHSRFRLEGRDVHVDLPVSIDD
EEECCHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCEEEECCCEEEEEECCCCCH
AVLGGKQEVETLDGRISVKIPAWSSSDRVLRLKEKGLPLKAGGRGDLYVHVRIMLPEGGD
HHCCCHHHHHHCCCEEEEEECCCCCCCCEEEECCCCCCEECCCCCCEEEEEEEEECCCCC
KELEDFLQKRRVV
HHHHHHHHHHCCC
>Mature Secondary Structure
MRDPYSVLGVAKTAKPEEIKSAFRKLAKKHHPDQNQDDPKAQERFAEVNQAYEIIGDKDK
CCCCHHHHEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHH
RAQFDRGEIDVEGKPVFQGFAGGQGFGGAHGDPFAGFRQGGGNSHFEFRGGPGGFQGGGF
CCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCCCHHHCCCCCCCEEECCCCCCCCCCCC
GGAEDILNDLFGDAFGGGRSGARQRGPSKGADLSASIDISLSQAVGAEKVEAIFPNGKHL
CCHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCEEEEEEEEHHHCCCHHHEEECCCCCEE
KIKLPKFVEDGQTIRLKGQGEPLMGGTPGDALVTIRFKPHSRFRLEGRDVHVDLPVSIDD
EEECCHHHCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCEEEECCCEEEEEECCCCCH
AVLGGKQEVETLDGRISVKIPAWSSSDRVLRLKEKGLPLKAGGRGDLYVHVRIMLPEGGD
HHCCCHHHHHHCCCEEEEEECCCCCCCCEEEECCCCCCEECCCCCCEEEEEEEEECCCCC
KELEDFLQKRRVV
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA