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The map label for this gene is degU [H]

Identifier: 225851885

GI number: 225851885

Start: 371959

End: 372600

Strand: Direct

Name: degU [H]

Synonym: BMEA_A0378

Alternate gene names: 225851885

Gene position: 371959-372600 (Clockwise)

Preceding gene: 225851884

Following gene: 225851886

Centisome position: 17.5

GC content: 56.07

Gene sequence:

>642_bases
ATGACGAATGAATGCAAGATTCGCGTATTGTTGGTGGACAATCATCCGCTGGTGCTGGACGGCCTGCGCGCCGTGCTTGA
AACCTATGACGATATTGATATTGCCGGTGCGGCCTCCAATGCGCGCGTTGCACTTGAAATGGCGCTGGCCGTTAATCCCG
ACGTGGTGCTGATGGATATCAACATGCCGCTTCTGAACGGCATTGACGCCATCGAGCTTTTCAAGCGGCAGTTGCCCAAT
GTCCGTATTCTCATGCTCTCCATGCATGACAGCCGCGAATATATCTCCACCTCCATCATGCGCGGGGCCTCGGGCTATAT
CTTGAAAGATGTCTCGACCAACGAGATCGTGACAGCCATCCATGCTGTCGCCTCCGGCGGCACCTATTTTTCATCGGGCG
TTTCGGAAGCACTGCTCGAAAGCGGCGAGAAGAGATCCGAAGGCCTGTCGGCGCGTGAAAATGATGTGCTGGTTCTGGTG
GCGGAAGGCGGCAGCAATCGCGAGATCGCGGCCCGGCTCGGTATTTCCGAGGCAACTGTCGAAACGCACCGCAAGAATAT
CAAGAAGAAACTCGGTATCGCCAGCACGGCCGGCCTCACACGTTACGCCATCGAGAACCGGCTGTGCCTGTCTTCACTTT
AG

Upstream 100 bases:

>100_bases
TTGGCGGTGTGCTCTTGGTTGAAACGAGTGCAGATGGTACGCAACTGACCGCACGTCTGCCGAAATCGGCAACGGAAAGA
AGGCTGGAACCGGAAGTCGC

Downstream 100 bases:

>100_bases
GGCGGTTCCGCTTAAAACGAAATCGCTGGAACCGCTCTATCTCTTTGTTTTATCGCATTATTTAACGCATCGAAGCGGGA
TCGGAAATCAGTCCAGTGGA

Product: LuxR family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTNECKIRVLLVDNHPLVLDGLRAVLETYDDIDIAGAASNARVALEMALAVNPDVVLMDINMPLLNGIDAIELFKRQLPN
VRILMLSMHDSREYISTSIMRGASGYILKDVSTNEIVTAIHAVASGGTYFSSGVSEALLESGEKRSEGLSARENDVLVLV
AEGGSNREIAARLGISEATVETHRKNIKKKLGIASTAGLTRYAIENRLCLSSL

Sequences:

>Translated_213_residues
MTNECKIRVLLVDNHPLVLDGLRAVLETYDDIDIAGAASNARVALEMALAVNPDVVLMDINMPLLNGIDAIELFKRQLPN
VRILMLSMHDSREYISTSIMRGASGYILKDVSTNEIVTAIHAVASGGTYFSSGVSEALLESGEKRSEGLSARENDVLVLV
AEGGSNREIAARLGISEATVETHRKNIKKKLGIASTAGLTRYAIENRLCLSSL
>Mature_212_residues
TNECKIRVLLVDNHPLVLDGLRAVLETYDDIDIAGAASNARVALEMALAVNPDVVLMDINMPLLNGIDAIELFKRQLPNV
RILMLSMHDSREYISTSIMRGASGYILKDVSTNEIVTAIHAVASGGTYFSSGVSEALLESGEKRSEGLSARENDVLVLVA
EGGSNREIAARLGISEATVETHRKNIKKKLGIASTAGLTRYAIENRLCLSSL

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=33.9712918660287, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1787473, Length=190, Percent_Identity=33.6842105263158, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788521, Length=212, Percent_Identity=33.0188679245283, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1790102, Length=196, Percent_Identity=32.6530612244898, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1788712, Length=202, Percent_Identity=29.2079207920792, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1786747, Length=199, Percent_Identity=28.643216080402, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1788546, Length=205, Percent_Identity=29.2682926829268, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22981; Mature: 22850

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNECKIRVLLVDNHPLVLDGLRAVLETYDDIDIAGAASNARVALEMALAVNPDVVLMDI
CCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEEEEEECCCCEEEEEC
NMPLLNGIDAIELFKRQLPNVRILMLSMHDSREYISTSIMRGASGYILKDVSTNEIVTAI
CCHHHCCCCHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEECCCCHHHHHHH
HAVASGGTYFSSGVSEALLESGEKRSEGLSARENDVLVLVAEGGSNREIAARLGISEATV
HHHHCCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHH
ETHRKNIKKKLGIASTAGLTRYAIENRLCLSSL
HHHHHHHHHHHCCCHHCCHHHHHHHCCHHHCCC
>Mature Secondary Structure 
TNECKIRVLLVDNHPLVLDGLRAVLETYDDIDIAGAASNARVALEMALAVNPDVVLMDI
CCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEEEEEECCCCEEEEEC
NMPLLNGIDAIELFKRQLPNVRILMLSMHDSREYISTSIMRGASGYILKDVSTNEIVTAI
CCHHHCCCCHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHCCCCCEEEECCCCHHHHHHH
HAVASGGTYFSSGVSEALLESGEKRSEGLSARENDVLVLVAEGGSNREIAARLGISEATV
HHHHCCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEECCCCCCEEEEECCCCHHHH
ETHRKNIKKKLGIASTAGLTRYAIENRLCLSSL
HHHHHHHHHHHCCCHHCCHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]