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The map label for this gene is panC [H]

Identifier: 225851874

GI number: 225851874

Start: 360630

End: 361511

Strand: Direct

Name: panC [H]

Synonym: BMEA_A0367

Alternate gene names: 225851874

Gene position: 360630-361511 (Clockwise)

Preceding gene: 225851873

Following gene: 225851875

Centisome position: 16.97

GC content: 61.22

Gene sequence:

>882_bases
ATGCAGATCATCCACACCATCGAGGAATTGCGCCAGGCGCTTGCGCCTGCCAGGCAGCAGGGCAAAAAGATCGGCTTCGT
GCCGACTATGGGTTATCTCCATAAGGGCCATCTGGAGCTTGTGCGCCGCGCGCGCGTGGAAAACGATGTGACGCTGGTGT
CGATCTTCGTCAACCCACTGCAATTTGGCGCGAATGAAGACCTCGGCAGATATCCCCGTGATCTGGAGCGCGACGCCGGC
CTTTTGCATGACGCGCAGGTGGATTATCTTTTTGCGCCTACGGTGAGCGATATGTATCCTCGTCCCATGCAGACAGTGGT
GGACGTGCCCCCGCTTGGCAACCAGATGGAAGGTGAGGCGCGCCCCGGCCATTTTGCCGGTGTTGCAACGGTGGTGAGCA
AGCTATTCAACATCGTCGGGCCGGATGCAGCCTATTTCGGCGAGAAGGACTTCCAGCAGCTCGTCATCATCCGCCGTATG
GTGGACGACATGGCCATTCCGGTGCGCATCGTCGGTGTTGAAACCGTGCGCGAGGATGACGGGCTCGCCTGTTCGTCGCG
CAATGTCTACCTGACGCCCGAACAGCGCCGCGCCGCCATCATCGTCCCGCAGGCGCTTGATGAGGCTGACCGGCTCTACC
GTTCAGGCATGGATGACCCGGATGCGCTGGAAGCAGCCATTCGCACATTCATCGGCAGGCAACCGCTGGCCGTGCCCGAA
GTGATTGCGATCCGCGATCCCGAAACGCTGGAGCGGCTGCCCGCCCTGCAGGGAAGGCCGATCCTCGTTGCGCTTTTCGT
GCGTGTGGGGGCGACGCGGCTTCTGGATAATCGTGTGATCGGACATGCGGCGCCACAGATCACACAGGAAAGGGCAGCCT
GA

Upstream 100 bases:

>100_bases
TGATCATGCCTTAGAGCATTTTCGAGCCAAAACTGCTTCGCACTTTTGCTGGAAATGCTTTAGGACTTGCGGCCAGTCAT
TCGGCTGGCAGGAGGACCCC

Downstream 100 bases:

>100_bases
CATGAGTGCACCCGTAACCCGCAAACGGCTGACGCCGAAGGTTATTCAGGCGATGAAGGGCGAGTGTCCCATCGTCAGCC
TCACCGCTTATACGACGCCG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MQIIHTIEELRQALAPARQQGKKIGFVPTMGYLHKGHLELVRRARVENDVTLVSIFVNPLQFGANEDLGRYPRDLERDAG
LLHDAQVDYLFAPTVSDMYPRPMQTVVDVPPLGNQMEGEARPGHFAGVATVVSKLFNIVGPDAAYFGEKDFQQLVIIRRM
VDDMAIPVRIVGVETVREDDGLACSSRNVYLTPEQRRAAIIVPQALDEADRLYRSGMDDPDALEAAIRTFIGRQPLAVPE
VIAIRDPETLERLPALQGRPILVALFVRVGATRLLDNRVIGHAAPQITQERAA

Sequences:

>Translated_293_residues
MQIIHTIEELRQALAPARQQGKKIGFVPTMGYLHKGHLELVRRARVENDVTLVSIFVNPLQFGANEDLGRYPRDLERDAG
LLHDAQVDYLFAPTVSDMYPRPMQTVVDVPPLGNQMEGEARPGHFAGVATVVSKLFNIVGPDAAYFGEKDFQQLVIIRRM
VDDMAIPVRIVGVETVREDDGLACSSRNVYLTPEQRRAAIIVPQALDEADRLYRSGMDDPDALEAAIRTFIGRQPLAVPE
VIAIRDPETLERLPALQGRPILVALFVRVGATRLLDNRVIGHAAPQITQERAA
>Mature_293_residues
MQIIHTIEELRQALAPARQQGKKIGFVPTMGYLHKGHLELVRRARVENDVTLVSIFVNPLQFGANEDLGRYPRDLERDAG
LLHDAQVDYLFAPTVSDMYPRPMQTVVDVPPLGNQMEGEARPGHFAGVATVVSKLFNIVGPDAAYFGEKDFQQLVIIRRM
VDDMAIPVRIVGVETVREDDGLACSSRNVYLTPEQRRAAIIVPQALDEADRLYRSGMDDPDALEAAIRTFIGRQPLAVPE
VIAIRDPETLERLPALQGRPILVALFVRVGATRLLDNRVIGHAAPQITQERAA

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=284, Percent_Identity=47.5352112676056, Blast_Score=234, Evalue=4e-63,
Organism=Saccharomyces cerevisiae, GI6322046, Length=312, Percent_Identity=38.1410256410256, Blast_Score=190, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 32525; Mature: 32525

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIIHTIEELRQALAPARQQGKKIGFVPTMGYLHKGHLELVRRARVENDVTLVSIFVNPL
CHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHH
QFGANEDLGRYPRDLERDAGLLHDAQVDYLFAPTVSDMYPRPMQTVVDVPPLGNQMEGEA
HCCCCCCCCCCCHHHHHHCCCCCCCCCCEEECCCHHHHCCCCHHHHCCCCCCCCCCCCCC
RPGHFAGVATVVSKLFNIVGPDAAYFGEKDFQQLVIIRRMVDDMAIPVRIVGVETVREDD
CCCHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHEECCC
GLACSSRNVYLTPEQRRAAIIVPQALDEADRLYRSGMDDPDALEAAIRTFIGRQPLAVPE
CCEECCCCEEECCCCCCEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
VIAIRDPETLERLPALQGRPILVALFVRVGATRLLDNRVIGHAAPQITQERAA
EEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC
>Mature Secondary Structure
MQIIHTIEELRQALAPARQQGKKIGFVPTMGYLHKGHLELVRRARVENDVTLVSIFVNPL
CHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHH
QFGANEDLGRYPRDLERDAGLLHDAQVDYLFAPTVSDMYPRPMQTVVDVPPLGNQMEGEA
HCCCCCCCCCCCHHHHHHCCCCCCCCCCEEECCCHHHHCCCCHHHHCCCCCCCCCCCCCC
RPGHFAGVATVVSKLFNIVGPDAAYFGEKDFQQLVIIRRMVDDMAIPVRIVGVETVREDD
CCCHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHEECCC
GLACSSRNVYLTPEQRRAAIIVPQALDEADRLYRSGMDDPDALEAAIRTFIGRQPLAVPE
CCEECCCCEEECCCCCCEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCC
VIAIRDPETLERLPALQGRPILVALFVRVGATRLLDNRVIGHAAPQITQERAA
EEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA