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The map label for this gene is pgi [H]

Identifier: 225851832

GI number: 225851832

Start: 314735

End: 316384

Strand: Direct

Name: pgi [H]

Synonym: BMEA_A0320

Alternate gene names: 225851832

Gene position: 314735-316384 (Clockwise)

Preceding gene: 225851828

Following gene: 225851833

Centisome position: 14.81

GC content: 60.55

Gene sequence:

>1650_bases
ATGGCAAGAGACGCGACGAAGCTTGAAGCAACGGTCGCAAAGCTGAAAAAGCATTGGGCGGAATCGGCCCCGCGCGATAT
GCGCGCGGCATTCAGCGCCGACCCCGGCCGGTTCGGGCGATATTCGCTCTGCCTGGATGATCTTCTGTTCGACTGGTCGA
AGTGCCGGGTTAACGACGAGACCATGGCGCTGTTGAAAGAGCTGGCCGTCGCTGCCGATGTGGAAGGGCGCCGCGCCGCC
ATGTTCGCGGGCGAGCATATCAACAATACCGAAGACCGCGCCGTTCTGCATGTGGCGCTGCGCGACACGTCCTCGAAGGA
AGTGCTGGTTGACGGGCATAATGTACTGCCGGATGTGAAACATGTGCTCGACCGCATGGCCGCTTTTGCGGATGGCATCC
GGTCCGGCGCGTTGAAGGGCGCGACCGGCCGGAAGATTACCGATATCGTGAATATCGGCATTGGCGGTTCCGATCTGGGG
CCTGTCATGGCGACGCTGGCGCTTGCGCCCTATCATGATGAGCCACGCGCGCATTTCGTTTCCAATATCGATGGCGCGCA
TATTGCCGACACGCTTTCGCCGCTTGATCCGGCATCGACGCTTATCATTGTCGCGTCGAAGACTTTTACGACCATTGAAA
CCATGACGAACGCGCAGACGGCGCGCAAATGGGTGGCAGACACCCTGGGCGAGGCGGCGGTGGGCGCGCATTTTGCTGCC
GTTTCCACTGCGCTCGACAAGGTTGCGGCCTTCGGCATTCCTGAAGATCGTGTTTTCGGCTTCTGGGACTGGGTTGGCGG
GCGTTATTCGGTCTGGTCGGCCATCGGCCTGCCGGTGATGATCGCCGTCGGCCCGGATAATTTCCGCAAGTTCCTTGCGG
GCGCACACGCCATGGATGTGCATTTCCGCGATGCGCCACTGGAAAAGAACCTGCCCGTCATGCTCGGCCTCATCGGCTAT
TGGCATCGCGCAATCTGCGGTTATGGCAGCCGCGCCATCATTCCTTATGACCAGCGCCTTTCGCGCCTCCCGGCCTATTT
GCAGCAGCTCGATATGGAATCGAACGGCAAGAGCGTGACGCTGGATGGCAAGCCGGTTTCCGGCCCAACCGGCCCCGTTG
TCTGGGGTGAGCCCGGCACCAATGGCCAGCACGCCTTTTTCCAGCTTCTGCATCAGGGAACCGATACGATCCCGCTGGAA
TTCATCGTGGCGGCCAAGGGCCACGAGCCGACACTGGATCACCAGCATGAAATGCTGATGGCAAACTGCCTTGCCCAGTC
CGAAGCCCTGATGAAAGGCCGCACGCTGGACGAGGCGCGTGCGCAGTTGCAGGCAAAGAACCTGCCTGCGTCGCAAGTGG
AGCGCATTGCCCCGCACCGCGTCTTTTCCGGCAACCGCCCATCCCTGACGCTCATCCATGACATGCTCGACCCCTATACG
CTGGGTCGCCTGATCGCGCTTTACGAACATCGTGTTTTCGTCGAAGCGCAGATTTTCGGCATCAATGCCTTCGATCAATG
GGGCGTGGAACTGGGTAAGGAACTGGCGACGGAACTTTTGCCGGTTGTATCGGGCAAGGAAGGGGCGAGTGGTCGCGACG
CTTCCACGCAAGGGCTTGTCGCGCATCTGCATGCGCGAAGGAAAGCTTGA

Upstream 100 bases:

>100_bases
CGCTCTGTCTAAAGTGGAAGTTGGGTAATTTATTTGCCGCAAACCTTCTCTAAACCGCCTAATATCCGAGATTAAATCGA
TTTGATTCGGGAGTAGCACC

Downstream 100 bases:

>100_bases
CCGCATTATCTGTAAGGTTAGAAATACGAGAAAAGCCGGACCAGAAGCATGATCCCGAAAAGTGTAAGCGGCTTCGGAAC
AAGATCGTGCTTCTGGCCCG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MARDATKLEATVAKLKKHWAESAPRDMRAAFSADPGRFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAA
MFAGEHINNTEDRAVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLG
PVMATLALAPYHDEPRAHFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAAVGAHFAA
VSTALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGY
WHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLE
FIVAAKGHEPTLDHQHEMLMANCLAQSEALMKGRTLDEARAQLQAKNLPASQVERIAPHRVFSGNRPSLTLIHDMLDPYT
LGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEGASGRDASTQGLVAHLHARRKA

Sequences:

>Translated_549_residues
MARDATKLEATVAKLKKHWAESAPRDMRAAFSADPGRFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAA
MFAGEHINNTEDRAVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLG
PVMATLALAPYHDEPRAHFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAAVGAHFAA
VSTALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGY
WHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLE
FIVAAKGHEPTLDHQHEMLMANCLAQSEALMKGRTLDEARAQLQAKNLPASQVERIAPHRVFSGNRPSLTLIHDMLDPYT
LGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEGASGRDASTQGLVAHLHARRKA
>Mature_548_residues
ARDATKLEATVAKLKKHWAESAPRDMRAAFSADPGRFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAAM
FAGEHINNTEDRAVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGP
VMATLALAPYHDEPRAHFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAAVGAHFAAV
STALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYW
HRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEF
IVAAKGHEPTLDHQHEMLMANCLAQSEALMKGRTLDEARAQLQAKNLPASQVERIAPHRVFSGNRPSLTLIHDMLDPYTL
GRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEGASGRDASTQGLVAHLHARRKA

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=544, Percent_Identity=51.2867647058823, Blast_Score=566, Evalue=1e-161,
Organism=Homo sapiens, GI296080693, Length=531, Percent_Identity=48.3992467043315, Blast_Score=511, Evalue=1e-145,
Organism=Escherichia coli, GI1790457, Length=535, Percent_Identity=50.0934579439252, Blast_Score=553, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71996708, Length=543, Percent_Identity=50.0920810313076, Blast_Score=554, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71996703, Length=543, Percent_Identity=50.0920810313076, Blast_Score=553, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6319673, Length=547, Percent_Identity=49.7257769652651, Blast_Score=523, Evalue=1e-149,
Organism=Drosophila melanogaster, GI24651916, Length=548, Percent_Identity=50.1824817518248, Blast_Score=557, Evalue=1e-159,
Organism=Drosophila melanogaster, GI24651914, Length=548, Percent_Identity=50.1824817518248, Blast_Score=557, Evalue=1e-159,
Organism=Drosophila melanogaster, GI17737445, Length=548, Percent_Identity=50.1824817518248, Blast_Score=557, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 59643; Mature: 59512

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARDATKLEATVAKLKKHWAESAPRDMRAAFSADPGRFGRYSLCLDDLLFDWSKCRVNDE
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHCCCHH
TMALLKELAVAADVEGRRAAMFAGEHINNTEDRAVLHVALRDTSSKEVLVDGHNVLPDVK
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCHHHH
HVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPYHDEPRAHFV
HHHHHHHHHHHHHHHCCCCCCCCCEEEHEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHH
SNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAAVGAHFAA
HCCCCCHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSTALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNFRKFLAGAHAMDV
HHHHHHHHHHCCCCCHHEEEEHHCCCCCCHHHHHCCCCEEEEECCHHHHHHHHCCCEEEE
HFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVT
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHCCCCCCCEEE
LDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHEPTLDHQHEMLM
ECCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHH
ANCLAQSEALMKGRTLDEARAQLQAKNLPASQVERIAPHRVFSGNRPSLTLIHDMLDPYT
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEEHHHHHCCHHH
LGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEGASGRDASTQGLV
HHHHHHHHHCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
AHLHARRKA
HHHHHHCCC
>Mature Secondary Structure 
ARDATKLEATVAKLKKHWAESAPRDMRAAFSADPGRFGRYSLCLDDLLFDWSKCRVNDE
CCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHCHHHHCCCHH
TMALLKELAVAADVEGRRAAMFAGEHINNTEDRAVLHVALRDTSSKEVLVDGHNVLPDVK
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEEEEECCCCCEEEECCCCCCHHHH
HVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPYHDEPRAHFV
HHHHHHHHHHHHHHHCCCCCCCCCEEEHEEEECCCCCCHHHHHHHHHHCCCCCCCHHHHH
SNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAAVGAHFAA
HCCCCCHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSTALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNFRKFLAGAHAMDV
HHHHHHHHHHCCCCCHHEEEEHHCCCCCCHHHHHCCCCEEEEECCHHHHHHHHCCCEEEE
HFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVT
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHCCCCCCCEEE
LDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHEPTLDHQHEMLM
ECCCCCCCCCCCEEECCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHH
ANCLAQSEALMKGRTLDEARAQLQAKNLPASQVERIAPHRVFSGNRPSLTLIHDMLDPYT
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCEEHHHHHCCHHH
LGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEGASGRDASTQGLV
HHHHHHHHHCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
AHLHARRKA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA