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The map label for this gene is mutT [C]

Identifier: 225851828

GI number: 225851828

Start: 310700

End: 311089

Strand: Direct

Name: mutT [C]

Synonym: BMEA_A0315

Alternate gene names: 225851828

Gene position: 310700-311089 (Clockwise)

Preceding gene: 225851825

Following gene: 225851832

Centisome position: 14.62

GC content: 60.77

Gene sequence:

>390_bases
ATGAAGACGATTCGTATTTCAGCAGCCATTATCCGCGATGAAGCGGGCCGTTTCCTTCTCGTGCGCAAGCGCGGTAGCGA
GATATTCTTTCAGCCCGGCGGCAAGATCGATGACGGCGAAGACCCGGAAACCTGCCTCTTGCGCGAGATCGAGGAGGAAC
TGGGCATCCGCATTGGCCGCAGCCAGTTGCGTTATGCGGCGAAAATGGCAGCCCCTGCCGCCAACGAAACGGATGCGACG
GTGGAAGCCGAGCTTTACCATCTTACGCTGGAGGAAGGGCAGGTGCCCATCGCCTCCAGCGAGATTGAGGAATTGCGGTG
GAACCCGCCGGGCGACACCACGCGGCCTGTCGCCCTTCTGTCGCAGGCCATTCAGGCACGGTTTGCCTGA

Upstream 100 bases:

>100_bases
GACCACGCGCCGAAGCCGCAAATTTTTATGATGAGGCTGCACGCGCTGTCAGCGCCATTATTCTTGACGGCATCCGCCTG
CGTGATGATGCTCCGAAATC

Downstream 100 bases:

>100_bases
ACGCGCTTCGCACTTTTTTGGAAATGCTCTATTGCGAAAGTCTTTTATTCGGCGGCCTCCTTCATGGCCGCCGGATTGTT
CGGATGCGTGGTCCAGTTGG

Product: nudix domain-containing protein

Products: 8-Oxo-Dgmp; Pyrophosphate. [C]

Alternate protein names: MutT Family NTP Pyrophosphatase; NUDIX Family Hydrolase; NTP Pyrophosphohydrolase; MutT/Nudix Family Hydrolase; MutT/Nudix Family Protein; Hydrolase Nudix Family; Hydrolase Nudix Family Protein; NUDIX Family Protein

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MKTIRISAAIIRDEAGRFLLVRKRGSEIFFQPGGKIDDGEDPETCLLREIEEELGIRIGRSQLRYAAKMAAPAANETDAT
VEAELYHLTLEEGQVPIASSEIEELRWNPPGDTTRPVALLSQAIQARFA

Sequences:

>Translated_129_residues
MKTIRISAAIIRDEAGRFLLVRKRGSEIFFQPGGKIDDGEDPETCLLREIEEELGIRIGRSQLRYAAKMAAPAANETDAT
VEAELYHLTLEEGQVPIASSEIEELRWNPPGDTTRPVALLSQAIQARFA
>Mature_129_residues
MKTIRISAAIIRDEAGRFLLVRKRGSEIFFQPGGKIDDGEDPETCLLREIEEELGIRIGRSQLRYAAKMAAPAANETDAT
VEAELYHLTLEEGQVPIASSEIEELRWNPPGDTTRPVALLSQAIQARFA

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 14307; Mature: 14307

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIRISAAIIRDEAGRFLLVRKRGSEIFFQPGGKIDDGEDPETCLLREIEEELGIRIGR
CCEEEEEHEEEECCCCCEEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEECH
SQLRYAAKMAAPAANETDATVEAELYHLTLEEGQVPIASSEIEELRWNPPGDTTRPVALL
HHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHCCCCCCCCCCHHHHHH
SQAIQARFA
HHHHHHCCC
>Mature Secondary Structure
MKTIRISAAIIRDEAGRFLLVRKRGSEIFFQPGGKIDDGEDPETCLLREIEEELGIRIGR
CCEEEEEHEEEECCCCCEEEEEECCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEECH
SQLRYAAKMAAPAANETDATVEAELYHLTLEEGQVPIASSEIEELRWNPPGDTTRPVALL
HHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHCCCCCCCCCCHHHHHH
SQAIQARFA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 8-Oxo-Dgtp; H2O [C]

Specific reaction: 8-Oxo-Dgtp + H2O = 8-Oxo-Dgmp + Pyrophosphate. [C]

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA