Click here to switch to the map view.

The map label for this gene is intZ [H]

Identifier: 225851776

GI number: 225851776

Start: 259204

End: 260400

Strand: Direct

Name: intZ [H]

Synonym: BMEA_A0257

Alternate gene names: 225851776

Gene position: 259204-260400 (Clockwise)

Preceding gene: 225851772

Following gene: 225851778

Centisome position: 12.19

GC content: 55.47

Gene sequence:

>1197_bases
GTGCGTGCAATAAACCGATTGAGCGCAAGGGCGGCAACAACATTGGGACCGGGGAAGCACAATGACGGTGCGGGCCTTTG
GCTGCACAAGCGCCCGGATGGTGGCGGGCAATGGATTCTCCGTGTCACCATTCATGGTAGGCGCAGAGAGATGGGGCTTG
GCTCTGCGCTTGAGGTGTCATTGAAAGAGGCGCGTGAAGCCGCTGAAAAGTGGCGCGCCATGGTTCGCTCGAACATCGAT
CCAATCAAAGAGCGCGAACGCCAGAAGCGTGAAGCTGCTCGCAATCTGCATTTGTTGAAAGATGTGGCAATTGATGCATT
TGAGAGCCGGAAAGCTGAATTGAAGGGCGACGGTGACGCTGGTCGCTGGTTCAGCCCGCTTGAGCATCATATTTTGCCGA
AACTCGGCAAGGTTCCGGTAGCCGATATTGATCAGAAGGATATTCGCGACACGCTTGCGCCGATCTGGCATTCGAAAGCT
GAAACCGCACGGAAGGCTATCAATAGACTTGCCATATGCATGAGGCATGCAGCGGCCCTTGGTTTGGACGTTGATTTGCA
GGCAACAGAAAAAGCTCGCGCCCTTCTCGGTAAGCAGCGCCATAAAGCCCAGAATATCCCGGCCATGCCGTGGCAGGAGG
TCCCTGCCTTTTATGCGACCTTGACTGACGACTCGGTTACGCATCTTGCTATGCGCCTGCTTATCCTGACGGGCGTTCGG
TCGGGGCCGCTTCGTTCGATCCATGAGAGCCAGATAGACGGCAATGTCTGGACCATTCCCGGTGAAGCCATGAAAGGCCG
GAAGGATGCAACGAATGACTTCCGTGTCCCGCTTACAGTCGAGGCGATGAAAGTTATAGATATTGCCCGCCGCCATGCGC
GTGACGGCTTTCTTTTCCCGAATGTTCGCAGCGGAGTTATCAGCGATATGACGCTGGGTATGTTCATGCGCAGGGCCAAG
CTTGAAGCACGTCCGCATGGCTTCCGCTCCAGCTTGCGGGACTGGATAGCTGAAACGACAGATACGCCCCACGATATTGC
AGAAACGGTTCTTGGGCATACGGTCGGCGGATCGGTCGAGCGTGCCTATCGACGTACTGATTTCTTGGAACAGCGGCGTG
TTTTGATGGAGCGCTGGGCAAACCATGTGGCCGGTAATGGTGCTCAGATTTTACAGCTTATGAAGGCAGGAGCATGA

Upstream 100 bases:

>100_bases
TGTTACGTTCAATATCAGCAATTCTCATCATCTTTCATTTAATCGCATGATGAAGGGGGGATTGGTGGGTGGGTAGAATT
AGTCTGGTAGGGCGACAAAG

Downstream 100 bases:

>100_bases
AAAAGTCGCGCAACCACAAGGAATTGGAAACAGTCTTGTCAAATTTGAACGCGGCGCGAGCTGATCCTGATGATGGGTTT
GTCATCCTGTCTCAGTCAGA

Product: putative integrase DNA protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MRAINRLSARAATTLGPGKHNDGAGLWLHKRPDGGGQWILRVTIHGRRREMGLGSALEVSLKEAREAAEKWRAMVRSNID
PIKERERQKREAARNLHLLKDVAIDAFESRKAELKGDGDAGRWFSPLEHHILPKLGKVPVADIDQKDIRDTLAPIWHSKA
ETARKAINRLAICMRHAAALGLDVDLQATEKARALLGKQRHKAQNIPAMPWQEVPAFYATLTDDSVTHLAMRLLILTGVR
SGPLRSIHESQIDGNVWTIPGEAMKGRKDATNDFRVPLTVEAMKVIDIARRHARDGFLFPNVRSGVISDMTLGMFMRRAK
LEARPHGFRSSLRDWIAETTDTPHDIAETVLGHTVGGSVERAYRRTDFLEQRRVLMERWANHVAGNGAQILQLMKAGA

Sequences:

>Translated_398_residues
MRAINRLSARAATTLGPGKHNDGAGLWLHKRPDGGGQWILRVTIHGRRREMGLGSALEVSLKEAREAAEKWRAMVRSNID
PIKERERQKREAARNLHLLKDVAIDAFESRKAELKGDGDAGRWFSPLEHHILPKLGKVPVADIDQKDIRDTLAPIWHSKA
ETARKAINRLAICMRHAAALGLDVDLQATEKARALLGKQRHKAQNIPAMPWQEVPAFYATLTDDSVTHLAMRLLILTGVR
SGPLRSIHESQIDGNVWTIPGEAMKGRKDATNDFRVPLTVEAMKVIDIARRHARDGFLFPNVRSGVISDMTLGMFMRRAK
LEARPHGFRSSLRDWIAETTDTPHDIAETVLGHTVGGSVERAYRRTDFLEQRRVLMERWANHVAGNGAQILQLMKAGA
>Mature_398_residues
MRAINRLSARAATTLGPGKHNDGAGLWLHKRPDGGGQWILRVTIHGRRREMGLGSALEVSLKEAREAAEKWRAMVRSNID
PIKERERQKREAARNLHLLKDVAIDAFESRKAELKGDGDAGRWFSPLEHHILPKLGKVPVADIDQKDIRDTLAPIWHSKA
ETARKAINRLAICMRHAAALGLDVDLQATEKARALLGKQRHKAQNIPAMPWQEVPAFYATLTDDSVTHLAMRLLILTGVR
SGPLRSIHESQIDGNVWTIPGEAMKGRKDATNDFRVPLTVEAMKVIDIARRHARDGFLFPNVRSGVISDMTLGMFMRRAK
LEARPHGFRSSLRDWIAETTDTPHDIAETVLGHTVGGSVERAYRRTDFLEQRRVLMERWANHVAGNGAQILQLMKAGA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=396, Percent_Identity=29.2929292929293, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788690, Length=377, Percent_Identity=26.525198938992, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1788974, Length=390, Percent_Identity=28.2051282051282, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44530; Mature: 44530

Theoretical pI: Translated: 10.90; Mature: 10.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAINRLSARAATTLGPGKHNDGAGLWLHKRPDGGGQWILRVTIHGRRREMGLGSALEVS
CCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEECCHHHCCCCHHHHHH
LKEAREAAEKWRAMVRSNIDPIKERERQKREAARNLHLLKDVAIDAFESRKAELKGDGDA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GRWFSPLEHHILPKLGKVPVADIDQKDIRDTLAPIWHSKAETARKAINRLAICMRHAAAL
CCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLDVDLQATEKARALLGKQRHKAQNIPAMPWQEVPAFYATLTDDSVTHLAMRLLILTGVR
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHEECCCCHHHHHHHHHHHHHCCC
SGPLRSIHESQIDGNVWTIPGEAMKGRKDATNDFRVPLTVEAMKVIDIARRHARDGFLFP
CCCHHHHHHHHCCCCEEECCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
NVRSGVISDMTLGMFMRRAKLEARPHGFRSSLRDWIAETTDTPHDIAETVLGHTVGGSVE
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHH
RAYRRTDFLEQRRVLMERWANHVAGNGAQILQLMKAGA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRAINRLSARAATTLGPGKHNDGAGLWLHKRPDGGGQWILRVTIHGRRREMGLGSALEVS
CCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCEEEEEEEEECCHHHCCCCHHHHHH
LKEAREAAEKWRAMVRSNIDPIKERERQKREAARNLHLLKDVAIDAFESRKAELKGDGDA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GRWFSPLEHHILPKLGKVPVADIDQKDIRDTLAPIWHSKAETARKAINRLAICMRHAAAL
CCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLDVDLQATEKARALLGKQRHKAQNIPAMPWQEVPAFYATLTDDSVTHLAMRLLILTGVR
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHEECCCCHHHHHHHHHHHHHCCC
SGPLRSIHESQIDGNVWTIPGEAMKGRKDATNDFRVPLTVEAMKVIDIARRHARDGFLFP
CCCHHHHHHHHCCCCEEECCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
NVRSGVISDMTLGMFMRRAKLEARPHGFRSSLRDWIAETTDTPHDIAETVLGHTVGGSVE
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHH
RAYRRTDFLEQRRVLMERWANHVAGNGAQILQLMKAGA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]