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The map label for this gene is ycgM [C]

Identifier: 225851771

GI number: 225851771

Start: 254927

End: 255772

Strand: Direct

Name: ycgM [C]

Synonym: BMEA_A0252

Alternate gene names: 225851771

Gene position: 254927-255772 (Clockwise)

Preceding gene: 225851770

Following gene: 225851772

Centisome position: 11.99

GC content: 59.22

Gene sequence:

>846_bases
ATGAAATTTCTTCGTTATGGCGCAGCCGGTCAGGAAAAGCCCGGCCTTCTCGACGCCGATGGCACCATCCGCGATCTGTC
GGCCCATGTAAGCGATCTGTCGGGTGCCGCGCTTGACCCGGATGCGCTGGCAAAGCTTGGCGCGCTGGATGTCAATTCGC
TGCCGAAGGTGGAAGGCAATCCGCGCATCGGCCCTTGCGTGGCGGGCACGGGCAAGTTCATCTGCATCGGGCTCAATTAT
TCCGATCACGCTGCGGAAACGGGTGCGGCGGTGCCGTCAGAACCGATCATCTTCATGAAGGCCACTTCGGCCATCGTCGG
CCCCAATGACGATCTTGTCATTCCGCGCGGCTCGCAAAAGACCGATTGGGAAGTGGAGCTTGGCATTATCATCGGCAAAA
CCGCGAAATATGTAAGCGAGGAAGACGCGCTTGATTATGTCGCCGGTTACTGCACCATCCATGACGTTTCCGAACGTGCT
TTCCAGATCGAGCGCCAGGGCCAGTGGACCAAAGGCAAGTCCTGCGACACGTTCGGCCCGACCGGCCCGTGGCTGGTGAC
GAAGGACGAGATCGCAGACCCGGAAAACCTTGCCGTGTGGCTGAAGGTCAATGGCGAAACCATGCAGAACGGCTCATCCA
GAACGATGATCTATGGTGTGCGGCATCTGGTTTCCTATCTCTCGCAGTTCATGTCGCTGCAACCCGGTGACATTATTTCC
ACCGGCACGCCTCCGGGCGTGGGCATGGGCATGAAGCCGCCGCGCTATCTCAAGGCTGGTGATGTCGTGGAACTCGGTAT
CGAGGGCCTCGGATCGCAGAAGCAGAACGTGCGCGCCGATAGCTGA

Upstream 100 bases:

>100_bases
GCAGGCGCGACCTATACCACCGGGCAGGCCTATAACATCGATGGGGGATGGTCGATCTAACCCTGATCGCCCCCAACCTG
TCCCTTTAAGGAGTAGATTT

Downstream 100 bases:

>100_bases
TAATGGACACACAATGACGAAAATCACCGATCTGCGCGTTTTCGACCTGCGCTTTCCGACGTCGCAAAGTCTGGACGGCT
CGGATGCGATGAATCCCGAC

Product: fumarylacetoacetate hydrolase domain-containing protein 2

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKFLRYGAAGQEKPGLLDADGTIRDLSAHVSDLSGAALDPDALAKLGALDVNSLPKVEGNPRIGPCVAGTGKFICIGLNY
SDHAAETGAAVPSEPIIFMKATSAIVGPNDDLVIPRGSQKTDWEVELGIIIGKTAKYVSEEDALDYVAGYCTIHDVSERA
FQIERQGQWTKGKSCDTFGPTGPWLVTKDEIADPENLAVWLKVNGETMQNGSSRTMIYGVRHLVSYLSQFMSLQPGDIIS
TGTPPGVGMGMKPPRYLKAGDVVELGIEGLGSQKQNVRADS

Sequences:

>Translated_281_residues
MKFLRYGAAGQEKPGLLDADGTIRDLSAHVSDLSGAALDPDALAKLGALDVNSLPKVEGNPRIGPCVAGTGKFICIGLNY
SDHAAETGAAVPSEPIIFMKATSAIVGPNDDLVIPRGSQKTDWEVELGIIIGKTAKYVSEEDALDYVAGYCTIHDVSERA
FQIERQGQWTKGKSCDTFGPTGPWLVTKDEIADPENLAVWLKVNGETMQNGSSRTMIYGVRHLVSYLSQFMSLQPGDIIS
TGTPPGVGMGMKPPRYLKAGDVVELGIEGLGSQKQNVRADS
>Mature_281_residues
MKFLRYGAAGQEKPGLLDADGTIRDLSAHVSDLSGAALDPDALAKLGALDVNSLPKVEGNPRIGPCVAGTGKFICIGLNY
SDHAAETGAAVPSEPIIFMKATSAIVGPNDDLVIPRGSQKTDWEVELGIIIGKTAKYVSEEDALDYVAGYCTIHDVSERA
FQIERQGQWTKGKSCDTFGPTGPWLVTKDEIADPENLAVWLKVNGETMQNGSSRTMIYGVRHLVSYLSQFMSLQPGDIIS
TGTPPGVGMGMKPPRYLKAGDVVELGIEGLGSQKQNVRADS

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=201, Percent_Identity=51.7412935323383, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI40786394, Length=201, Percent_Identity=50.7462686567164, Blast_Score=221, Evalue=5e-58,
Organism=Homo sapiens, GI13654274, Length=208, Percent_Identity=38.4615384615385, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI66348062, Length=201, Percent_Identity=38.8059701492537, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI215422413, Length=201, Percent_Identity=38.8059701492537, Blast_Score=149, Evalue=4e-36,
Organism=Escherichia coli, GI1787428, Length=201, Percent_Identity=35.3233830845771, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17557057, Length=210, Percent_Identity=36.1904761904762, Blast_Score=148, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6324161, Length=229, Percent_Identity=31.8777292576419, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI28572127, Length=286, Percent_Identity=41.2587412587413, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI28571789, Length=212, Percent_Identity=36.7924528301887, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24663695, Length=289, Percent_Identity=30.7958477508651, Blast_Score=145, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 29909; Mature: 29909

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLRYGAAGQEKPGLLDADGTIRDLSAHVSDLSGAALDPDALAKLGALDVNSLPKVEGN
CCCEECCCCCCCCCCEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCC
PRIGPCVAGTGKFICIGLNYSDHAAETGAAVPSEPIIFMKATSAIVGPNDDLVIPRGSQK
CCCCCEEECCCCEEEEECCCCHHHHHCCCCCCCCCEEEEEECCEEECCCCCEEEECCCCC
TDWEVELGIIIGKTAKYVSEEDALDYVAGYCTIHDVSERAFQIERQGQWTKGKSCDTFGP
CCEEEEEEEEEECCHHHHCHHHHHHHHHHEEEEEEHHHHHEEHHCCCCCCCCCCCCCCCC
TGPWLVTKDEIADPENLAVWLKVNGETMQNGSSRTMIYGVRHLVSYLSQFMSLQPGDIIS
CCCEEEEHHHCCCCCCEEEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGMGMKPPRYLKAGDVVELGIEGLGSQKQNVRADS
CCCCCCCCCCCCCCCCCCCCCEEEECHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKFLRYGAAGQEKPGLLDADGTIRDLSAHVSDLSGAALDPDALAKLGALDVNSLPKVEGN
CCCEECCCCCCCCCCEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCC
PRIGPCVAGTGKFICIGLNYSDHAAETGAAVPSEPIIFMKATSAIVGPNDDLVIPRGSQK
CCCCCEEECCCCEEEEECCCCHHHHHCCCCCCCCCEEEEEECCEEECCCCCEEEECCCCC
TDWEVELGIIIGKTAKYVSEEDALDYVAGYCTIHDVSERAFQIERQGQWTKGKSCDTFGP
CCEEEEEEEEEECCHHHHCHHHHHHHHHHEEEEEEHHHHHEEHHCCCCCCCCCCCCCCCC
TGPWLVTKDEIADPENLAVWLKVNGETMQNGSSRTMIYGVRHLVSYLSQFMSLQPGDIIS
CCCEEEEHHHCCCCCCEEEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGMGMKPPRYLKAGDVVELGIEGLGSQKQNVRADS
CCCCCCCCCCCCCCCCCCCCCEEEECHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA