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The map label for this gene is glpD [H]

Identifier: 225851731

GI number: 225851731

Start: 210692

End: 212194

Strand: Direct

Name: glpD [H]

Synonym: BMEA_A0209

Alternate gene names: 225851731

Gene position: 210692-212194 (Clockwise)

Preceding gene: 225851730

Following gene: 225851732

Centisome position: 9.91

GC content: 60.21

Gene sequence:

>1503_bases
ATGGTGCAGGAAAAACAATTCGATATTTTTATTATAGGTGGCGGCATCAATGGCTGCGGCATTGCCCGTGATGCGGTGGG
GCGGGGCTTCACCGTTGGGCTGGCCGAGATGAACGATCTGGCAAGCGGCACCTCTTCGCGCGCAACCAAGCTCATTCACG
GTGGTTTGCGCTATCTGGAACATTATGAATTCCGGCTGGTGCGCGAGGCGCTGATGGAGCGCGAGGTGCTGTGGGCCAAT
GCGCCGCATATCATCCATCCGATGCGTTTCGTGCTGCCTTATCATAAGGGCGGCCTACGTCCCGCCTGGCTGTTGCGGCT
TGGCCTGTTTCTTTACGACCATCTGGGCGGCCGCAAGAAGCTTCCCGCCACGCGCACGCTCAACATGCGCACCGACAAGG
CCGGCGAACCGCTGAAACCGCTTTTCACCAAGGCTTTTGAATATTCCGATTGCTGGGTGGACGATGCGCGCTTCGTGGCG
CTCACCGCCCGCGATGCGGCTGATCGCGGCGCGAAGATCGCGACCCGAACGAGCGTCGTTGCCGCAAGCCGCGACGGGCA
GGGCTGGACCATCACACTGGAAGATACCGGCACCGGCAGGCGTGAGAACGTACACGCCCGCCTTCTGGTCAATGCCGCCG
GGCCGTGGGCCGACAAGGTTCTGCAAAGTGTGGAAGGCGACCGGCAATTGCACAATATCCGTCTGGTGCAGGGCAGCCAT
ATCGTCGTGCGCAGGAAGTTTTCCGACCCGCGCGCCTATTTCTTCCAGAACAACGACGGGCGCATCATCTTCGCCATTCC
TTATGAAGATGATTTCACCCTGATTGGCACCACGGATCAGGATTATAAGGGCGACCCGGCCAAGGTGGCGATCACCGACA
GCGAGACCGATTATCTCTGCCAGGCGGCAAGCGAATATTTCCGCGAGCCGGTGCGCCGGGAGGATATCGTCTGGACCTAT
TCCGGCGTGCGCCCGCTCTATGATGACGGGGCCAGCAAGGCGCAGGAGGCAACCCGCGACTATGTGCTGAAGGAAGATGC
GCCAGATGGTCTGGCGCCGCTCATCAATGTTTTCGGCGGCAAGCTCACCACAGCACGCAAGCTTGCCGAACATATGCTGC
AGAAAATCGAGCACCGGCTTGGCCGCAAGGGCGCCCCATGGACCCATGCAGCACCATTGCCAGGCGGGGATTTCGAGGAT
GTGGCTTTTGAAACGGAACTGAAGAAGCTTGAGGCAGCCTATCCTTTCCTTGATGCGCGCCGCCTGTTCCGGCTCTATGG
CACCCGGGCATATAAGCTTTTGGGGCAGGCTTCTTCGCTGGGCGATCTTGGCCGTCATTTTGGCAGCGATCTCTATGAGG
CGGAAGTGCGCTATCTTGTCGAAAATGAATGGGCGCGAAGCGCGGAAGACATTTTGTGGCGGCGCACCAAGCTCGGCCTG
CGCCTGACGGCGGCGGAAGTCGCGGCCGTGCAGGGCTTTGTGGAGCCTGCAATCGCCGCCTAA

Upstream 100 bases:

>100_bases
GGAGCAAAAAGATGATTAGTTTCGTTTGATTTTCATTTGCTTTCGTATTGAATGAATTATATTCGCTTTGGTGTTCGCAG
GCCGGTTTTCGGGGTACGCC

Downstream 100 bases:

>100_bases
AGGGTTGTGCTTGCCAGTCTTGCGTTAAAGAGCCATTATTCTCCCAGAGCCTGTTCCAAAAGTCGTCCTGTGCGGCTGCA
AATGGCAATTTATCTGCGTT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MVQEKQFDIFIIGGGINGCGIARDAVGRGFTVGLAEMNDLASGTSSRATKLIHGGLRYLEHYEFRLVREALMEREVLWAN
APHIIHPMRFVLPYHKGGLRPAWLLRLGLFLYDHLGGRKKLPATRTLNMRTDKAGEPLKPLFTKAFEYSDCWVDDARFVA
LTARDAADRGAKIATRTSVVAASRDGQGWTITLEDTGTGRRENVHARLLVNAAGPWADKVLQSVEGDRQLHNIRLVQGSH
IVVRRKFSDPRAYFFQNNDGRIIFAIPYEDDFTLIGTTDQDYKGDPAKVAITDSETDYLCQAASEYFREPVRREDIVWTY
SGVRPLYDDGASKAQEATRDYVLKEDAPDGLAPLINVFGGKLTTARKLAEHMLQKIEHRLGRKGAPWTHAAPLPGGDFED
VAFETELKKLEAAYPFLDARRLFRLYGTRAYKLLGQASSLGDLGRHFGSDLYEAEVRYLVENEWARSAEDILWRRTKLGL
RLTAAEVAAVQGFVEPAIAA

Sequences:

>Translated_500_residues
MVQEKQFDIFIIGGGINGCGIARDAVGRGFTVGLAEMNDLASGTSSRATKLIHGGLRYLEHYEFRLVREALMEREVLWAN
APHIIHPMRFVLPYHKGGLRPAWLLRLGLFLYDHLGGRKKLPATRTLNMRTDKAGEPLKPLFTKAFEYSDCWVDDARFVA
LTARDAADRGAKIATRTSVVAASRDGQGWTITLEDTGTGRRENVHARLLVNAAGPWADKVLQSVEGDRQLHNIRLVQGSH
IVVRRKFSDPRAYFFQNNDGRIIFAIPYEDDFTLIGTTDQDYKGDPAKVAITDSETDYLCQAASEYFREPVRREDIVWTY
SGVRPLYDDGASKAQEATRDYVLKEDAPDGLAPLINVFGGKLTTARKLAEHMLQKIEHRLGRKGAPWTHAAPLPGGDFED
VAFETELKKLEAAYPFLDARRLFRLYGTRAYKLLGQASSLGDLGRHFGSDLYEAEVRYLVENEWARSAEDILWRRTKLGL
RLTAAEVAAVQGFVEPAIAA
>Mature_500_residues
MVQEKQFDIFIIGGGINGCGIARDAVGRGFTVGLAEMNDLASGTSSRATKLIHGGLRYLEHYEFRLVREALMEREVLWAN
APHIIHPMRFVLPYHKGGLRPAWLLRLGLFLYDHLGGRKKLPATRTLNMRTDKAGEPLKPLFTKAFEYSDCWVDDARFVA
LTARDAADRGAKIATRTSVVAASRDGQGWTITLEDTGTGRRENVHARLLVNAAGPWADKVLQSVEGDRQLHNIRLVQGSH
IVVRRKFSDPRAYFFQNNDGRIIFAIPYEDDFTLIGTTDQDYKGDPAKVAITDSETDYLCQAASEYFREPVRREDIVWTY
SGVRPLYDDGASKAQEATRDYVLKEDAPDGLAPLINVFGGKLTTARKLAEHMLQKIEHRLGRKGAPWTHAAPLPGGDFED
VAFETELKKLEAAYPFLDARRLFRLYGTRAYKLLGQASSLGDLGRHFGSDLYEAEVRYLVENEWARSAEDILWRRTKLGL
RLTAAEVAAVQGFVEPAIAA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=524, Percent_Identity=31.8702290076336, Blast_Score=185, Evalue=8e-47,
Organism=Homo sapiens, GI285002231, Length=524, Percent_Identity=31.8702290076336, Blast_Score=185, Evalue=8e-47,
Organism=Escherichia coli, GI2367226, Length=474, Percent_Identity=49.57805907173, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI1788574, Length=492, Percent_Identity=27.0325203252033, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI115534726, Length=517, Percent_Identity=30.3675048355899, Blast_Score=172, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17509253, Length=511, Percent_Identity=30.3326810176125, Blast_Score=161, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6322036, Length=418, Percent_Identity=30.8612440191388, Blast_Score=144, Evalue=4e-35,
Organism=Drosophila melanogaster, GI161077125, Length=539, Percent_Identity=30.2411873840445, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24653942, Length=539, Percent_Identity=30.2411873840445, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24653944, Length=539, Percent_Identity=30.2411873840445, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI20130025, Length=539, Percent_Identity=30.2411873840445, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24586295, Length=525, Percent_Identity=28, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI19921278, Length=519, Percent_Identity=24.8554913294798, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 55983; Mature: 55983

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQEKQFDIFIIGGGINGCGIARDAVGRGFTVGLAEMNDLASGTSSRATKLIHGGLRYLE
CCCCCEEEEEEEECCCCCCCCCHHHCCCCEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHH
HYEFRLVREALMEREVLWANAPHIIHPMRFVLPYHKGGLRPAWLLRLGLFLYDHLGGRKK
HHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
LPATRTLNMRTDKAGEPLKPLFTKAFEYSDCWVDDARFVALTARDAADRGAKIATRTSVV
CCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEECCCEEEEEEECCCCCCCCEEEEHHEEE
AASRDGQGWTITLEDTGTGRRENVHARLLVNAAGPWADKVLQSVEGDRQLHNIRLVQGSH
EECCCCCCEEEEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEEEECCE
IVVRRKFSDPRAYFFQNNDGRIIFAIPYEDDFTLIGTTDQDYKGDPAKVAITDSETDYLC
EEEEEECCCCCEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCEEEEECCCHHHHH
QAASEYFREPVRREDIVWTYSGVRPLYDDGASKAQEATRDYVLKEDAPDGLAPLINVFGG
HHHHHHHHCCCCCCCEEEEECCCCCHHCCCHHHHHHHHHHCEECCCCCCHHHHHHHHHCC
KLTTARKLAEHMLQKIEHRLGRKGAPWTHAAPLPGGDFEDVAFETELKKLEAAYPFLDAR
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHH
RLFRLYGTRAYKLLGQASSLGDLGRHFGSDLYEAEVRYLVENEWARSAEDILWRRTKLGL
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
RLTAAEVAAVQGFVEPAIAA
EEHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVQEKQFDIFIIGGGINGCGIARDAVGRGFTVGLAEMNDLASGTSSRATKLIHGGLRYLE
CCCCCEEEEEEEECCCCCCCCCHHHCCCCEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHH
HYEFRLVREALMEREVLWANAPHIIHPMRFVLPYHKGGLRPAWLLRLGLFLYDHLGGRKK
HHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
LPATRTLNMRTDKAGEPLKPLFTKAFEYSDCWVDDARFVALTARDAADRGAKIATRTSVV
CCCCEEEECCCCCCCCCHHHHHHHHHCCCCCEECCCEEEEEEECCCCCCCCEEEEHHEEE
AASRDGQGWTITLEDTGTGRRENVHARLLVNAAGPWADKVLQSVEGDRQLHNIRLVQGSH
EECCCCCCEEEEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHCCCCCEEEEEEEECCE
IVVRRKFSDPRAYFFQNNDGRIIFAIPYEDDFTLIGTTDQDYKGDPAKVAITDSETDYLC
EEEEEECCCCCEEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCCCEEEEECCCHHHHH
QAASEYFREPVRREDIVWTYSGVRPLYDDGASKAQEATRDYVLKEDAPDGLAPLINVFGG
HHHHHHHHCCCCCCCEEEEECCCCCHHCCCHHHHHHHHHHCEECCCCCCHHHHHHHHHCC
KLTTARKLAEHMLQKIEHRLGRKGAPWTHAAPLPGGDFEDVAFETELKKLEAAYPFLDAR
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHH
RLFRLYGTRAYKLLGQASSLGDLGRHFGSDLYEAEVRYLVENEWARSAEDILWRRTKLGL
HHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCE
RLTAAEVAAVQGFVEPAIAA
EEHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]