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The map label for this gene is glpR [H]

Identifier: 225851730

GI number: 225851730

Start: 209819

End: 210610

Strand: Direct

Name: glpR [H]

Synonym: BMEA_A0208

Alternate gene names: 225851730

Gene position: 209819-210610 (Clockwise)

Preceding gene: 225851729

Following gene: 225851731

Centisome position: 9.87

GC content: 58.21

Gene sequence:

>792_bases
ATGCAGCTCACACCTCGCCATCATGCAATTGTGGAACTCGCGCGCCGCAAGGGGCAGGTTCTGGTGGACGATCTTGCCGT
GGCTTTCGATGTCACCCCGCAAACTGTGCGAAAAGATCTGAACGACCTCTGCCGCGCCCGCCTTCTGCGACGCATCCACG
GAGGTGCGCTCTATCCTTCCGGCGTGGAGAATATGGAATATGAGGCGCGCCGGCGTATCGCGGCGCATGAAAAGGAATCC
ATCGGGCGTGCCACGGCTGCGATCATCCCGGATGGCGCTTCGCTTTTCATCAATATCGGGACAACCACCGAGGCTGTCAG
TCATGCGCTTGTTGACCATAATCATCTGATGGTCATCACCAATAATATCAATGTCGCCAATACGCTGCGCGTCTACCCCT
CCATCGAAGTGGTGATTGCCGGCGGCGTGGTCCGCGCCTCCGATGGCGGCATCGTGGGCGAGGCGGCTGTGGATTTCATC
CGCCAGTTCAAGGTGGATTTCGCGATCATTGGAACATCGGCCATCGACGAAGATGGGGCCTTGCTCGATTTCGATTTCCG
CGAGGTGAAGGTGGCGCAGGCCATCATCGCCAATGCGCGCCATGTTATTCTGGTCACGGATTCCGCCAAGCTGGAACGAA
CCGCGCCGGTGCGCATCGGCCATCTGTCGCAGGTCAACACTTTCATCACCGACCGTTGCACTTCCCTGCAATTGCAGGAT
CTGTGCCGCGAACATGGGGTGGAGCTGATCGAAACCCTGGCCGGAAAGGAACCGGAGCAAAAAGATGATTAG

Upstream 100 bases:

>100_bases
GGTCCGGAACCTGGCGTGTAATCCGATCGGCGTGAAACGAGGGCCGATCAGATTATGCTTCAAAACAGACAGTCAGAACA
ATTCCAGTGCTGGAAACGCA

Downstream 100 bases:

>100_bases
TTTCGTTTGATTTTCATTTGCTTTCGTATTGAATGAATTATATTCGCTTTGGTGTTCGCAGGCCGGTTTTCGGGGTACGC
CATGGTGCAGGAAAAACAAT

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MQLTPRHHAIVELARRKGQVLVDDLAVAFDVTPQTVRKDLNDLCRARLLRRIHGGALYPSGVENMEYEARRRIAAHEKES
IGRATAAIIPDGASLFINIGTTTEAVSHALVDHNHLMVITNNINVANTLRVYPSIEVVIAGGVVRASDGGIVGEAAVDFI
RQFKVDFAIIGTSAIDEDGALLDFDFREVKVAQAIIANARHVILVTDSAKLERTAPVRIGHLSQVNTFITDRCTSLQLQD
LCREHGVELIETLAGKEPEQKDD

Sequences:

>Translated_263_residues
MQLTPRHHAIVELARRKGQVLVDDLAVAFDVTPQTVRKDLNDLCRARLLRRIHGGALYPSGVENMEYEARRRIAAHEKES
IGRATAAIIPDGASLFINIGTTTEAVSHALVDHNHLMVITNNINVANTLRVYPSIEVVIAGGVVRASDGGIVGEAAVDFI
RQFKVDFAIIGTSAIDEDGALLDFDFREVKVAQAIIANARHVILVTDSAKLERTAPVRIGHLSQVNTFITDRCTSLQLQD
LCREHGVELIETLAGKEPEQKDD
>Mature_263_residues
MQLTPRHHAIVELARRKGQVLVDDLAVAFDVTPQTVRKDLNDLCRARLLRRIHGGALYPSGVENMEYEARRRIAAHEKES
IGRATAAIIPDGASLFINIGTTTEAVSHALVDHNHLMVITNNINVANTLRVYPSIEVVIAGGVVRASDGGIVGEAAVDFI
RQFKVDFAIIGTSAIDEDGALLDFDFREVKVAQAIIANARHVILVTDSAKLERTAPVRIGHLSQVNTFITDRCTSLQLQD
LCREHGVELIETLAGKEPEQKDD

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=249, Percent_Identity=46.5863453815261, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI87082344, Length=246, Percent_Identity=39.4308943089431, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI1789059, Length=253, Percent_Identity=29.2490118577075, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788069, Length=252, Percent_Identity=25.7936507936508, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=26.984126984127, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI226510968, Length=227, Percent_Identity=28.1938325991189, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=27.3913043478261, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1790753, Length=206, Percent_Identity=28.1553398058252, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1789170, Length=230, Percent_Identity=26.0869565217391, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1787063, Length=224, Percent_Identity=22.3214285714286, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28794; Mature: 28794

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTPRHHAIVELARRKGQVLVDDLAVAFDVTPQTVRKDLNDLCRARLLRRIHGGALYPS
CCCCCHHHHHHHHHHHCCCEEEEEEHEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GVENMEYEARRRIAAHEKESIGRATAAIIPDGASLFINIGTTTEAVSHALVDHNHLMVIT
CCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCHHHHHHHHHHCCCEEEEEE
NNINVANTLRVYPSIEVVIAGGVVRASDGGIVGEAAVDFIRQFKVDFAIIGTSAIDEDGA
CCCCCCEEEEECCCEEEEEECCEEEECCCCEEHHHHHHHHHHHCCCEEEEECCCCCCCCC
LLDFDFREVKVAQAIIANARHVILVTDSAKLERTAPVRIGHLSQVNTFITDRCTSLQLQD
EEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHCCHHHHH
LCREHGVELIETLAGKEPEQKDD
HHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQLTPRHHAIVELARRKGQVLVDDLAVAFDVTPQTVRKDLNDLCRARLLRRIHGGALYPS
CCCCCHHHHHHHHHHHCCCEEEEEEHEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GVENMEYEARRRIAAHEKESIGRATAAIIPDGASLFINIGTTTEAVSHALVDHNHLMVIT
CCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEECCCHHHHHHHHHHCCCEEEEEE
NNINVANTLRVYPSIEVVIAGGVVRASDGGIVGEAAVDFIRQFKVDFAIIGTSAIDEDGA
CCCCCCEEEEECCCEEEEEECCEEEECCCCEEHHHHHHHHHHHCCCEEEEECCCCCCCCC
LLDFDFREVKVAQAIIANARHVILVTDSAKLERTAPVRIGHLSQVNTFITDRCTSLQLQD
EEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHCCHHHHH
LCREHGVELIETLAGKEPEQKDD
HHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]