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The map label for this gene is cysH [H]

Identifier: 225851714

GI number: 225851714

Start: 193569

End: 194327

Strand: Direct

Name: cysH [H]

Synonym: BMEA_A0189

Alternate gene names: 225851714

Gene position: 193569-194327 (Clockwise)

Preceding gene: 225851713

Following gene: 225851715

Centisome position: 9.11

GC content: 63.37

Gene sequence:

>759_bases
GTGCTGCCTGACGCCGACATTGCCGATGCGGATGAGCGCGGTGCCGCGCAAGCCCGGCTTCTCGAAGCAAGCCACGGCGC
ATCCGCGCCGCACGAAATAATCGCGCTTGTCACGCATGAGCTTTTCGAGGGGCGGGTTGCGGTTGTTTCGTCCTTCGGGG
CGGAATCGGCGGTGCTCCTGCATATGATCTCGCAGATCGACCGGGCAACGCCGGTGCTGTTTCTCGATACGGGCAAGCAT
TTTCGCGCCACACTCGATTATCGCCATCAACTGGTGGGTCGCCTGGGCCTTGCCGATGTGCGGGATATCCTGCCTGTTGC
GGACAGCCTGGCAAAGGAAGACCCGTTCGGCGCCTTGTCGATGACCGACAAGGACCGTTGCTGCTTTATCCGCAAGGTGG
AGCCGATGGCGCGCGCCGTTGCGCCTTACCGGGCATGGATGACGGGACGTAAGCAGTTTCAGGCATCCACCCGCAATGGG
CTGCCGGTGTTTGAATCGGTTGGCCCGCGTATCCGTATCAACCCGCTGGCGCGCTGGCGGGCCGAAGACCTCAGGGCCTA
TGCCGAAAAGTACAGCCTGCCGCCGCACCCGCTGACCGCGCAGGGCTATCGCTCCATCGGCTGCATGCCTTGCACACGCC
CCGTCTCGGAGGGCGAGGATCAGCGTGCCGGACGCTGGGCGGGGTCGGAAAAGACCGAATGCGGCATTCATCTTTCCGGC
CTTGCCGATAGCCTGAAGGGCATCCCGAAAGCTGTGTAA

Upstream 100 bases:

>100_bases
TATCTGGGCCTGCGCGAAAGTGCGGAGGAAACTTTCCTTGCCGCTTATCGCCGGGTGGGAATGGAGCCTTTCAAACGCGC
TCTTTATGGGGAGATAAGAA

Downstream 100 bases:

>100_bases
CGGTTTTTGGAACAGATGTGCGTTAAGAGACCATGCGAGTGAGAGAGCGTAAATGAGCAGCACAAACGAAACAAAACTCT
GGTCTCGCGATGGTTTCCGC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MLPDADIADADERGAAQARLLEASHGASAPHEIIALVTHELFEGRVAVVSSFGAESAVLLHMISQIDRATPVLFLDTGKH
FRATLDYRHQLVGRLGLADVRDILPVADSLAKEDPFGALSMTDKDRCCFIRKVEPMARAVAPYRAWMTGRKQFQASTRNG
LPVFESVGPRIRINPLARWRAEDLRAYAEKYSLPPHPLTAQGYRSIGCMPCTRPVSEGEDQRAGRWAGSEKTECGIHLSG
LADSLKGIPKAV

Sequences:

>Translated_252_residues
MLPDADIADADERGAAQARLLEASHGASAPHEIIALVTHELFEGRVAVVSSFGAESAVLLHMISQIDRATPVLFLDTGKH
FRATLDYRHQLVGRLGLADVRDILPVADSLAKEDPFGALSMTDKDRCCFIRKVEPMARAVAPYRAWMTGRKQFQASTRNG
LPVFESVGPRIRINPLARWRAEDLRAYAEKYSLPPHPLTAQGYRSIGCMPCTRPVSEGEDQRAGRWAGSEKTECGIHLSG
LADSLKGIPKAV
>Mature_252_residues
MLPDADIADADERGAAQARLLEASHGASAPHEIIALVTHELFEGRVAVVSSFGAESAVLLHMISQIDRATPVLFLDTGKH
FRATLDYRHQLVGRLGLADVRDILPVADSLAKEDPFGALSMTDKDRCCFIRKVEPMARAVAPYRAWMTGRKQFQASTRNG
LPVFESVGPRIRINPLARWRAEDLRAYAEKYSLPPHPLTAQGYRSIGCMPCTRPVSEGEDQRAGRWAGSEKTECGIHLSG
LADSLKGIPKAV

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=199, Percent_Identity=31.1557788944724, Blast_Score=94, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6325425, Length=225, Percent_Identity=35.1111111111111, Blast_Score=115, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27568; Mature: 27568

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPDADIADADERGAAQARLLEASHGASAPHEIIALVTHELFEGRVAVVSSFGAESAVLL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHH
HMISQIDRATPVLFLDTGKHFRATLDYRHQLVGRLGLADVRDILPVADSLAKEDPFGALS
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEE
MTDKDRCCFIRKVEPMARAVAPYRAWMTGRKQFQASTRNGLPVFESVGPRIRINPLARWR
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEECHHHHHH
AEDLRAYAEKYSLPPHPLTAQGYRSIGCMPCTRPVSEGEDQRAGRWAGSEKTECGIHLSG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCEEHHH
LADSLKGIPKAV
HHHHHHCCCCCC
>Mature Secondary Structure
MLPDADIADADERGAAQARLLEASHGASAPHEIIALVTHELFEGRVAVVSSFGAESAVLL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHH
HMISQIDRATPVLFLDTGKHFRATLDYRHQLVGRLGLADVRDILPVADSLAKEDPFGALS
HHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEE
MTDKDRCCFIRKVEPMARAVAPYRAWMTGRKQFQASTRNGLPVFESVGPRIRINPLARWR
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEECHHHHHH
AEDLRAYAEKYSLPPHPLTAQGYRSIGCMPCTRPVSEGEDQRAGRWAGSEKTECGIHLSG
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCEEHHH
LADSLKGIPKAV
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]