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The map label for this gene is rdgB [C]

Identifier: 225851707

GI number: 225851707

Start: 186763

End: 187425

Strand: Direct

Name: rdgB [C]

Synonym: BMEA_A0182

Alternate gene names: 225851707

Gene position: 186763-187425 (Clockwise)

Preceding gene: 225851706

Following gene: 225851708

Centisome position: 8.79

GC content: 59.58

Gene sequence:

>663_bases
ATGAGAATGCTGGAAAAGGGCAAGCTGATCGTCGCCTCGCACAATGCGGGCAAGCTCAGGGAATTTGACGGGTTGATCGG
CCCGTTCGGTTTCGAGGTGAGTTCGGTCGCGGCCCTTGGCCTGCCAGAACCGGACGAGACCGGCACGACCTTTGAGGAAA
ACGCCTATATCAAGGCGCTTGCCGCCGCCAAGGCAACGGGCTTTCCAGCTTTATCCGACGATTCCGGCCTGATGGTGGAC
GCACTTGACGGCGAACCGGGCGTCTACACGGCCAACTGGGCGGAAACGGAAGACGGCAAACGCGATTTCGACATGGCCAT
GCAGAAGGTGGAAAATCTTTTGCAGGAAAAGGGCGCGACGACGCCTGATAAACGCAAGGCGCGTTTCGTCTCGGTCATCT
GCCTTGCCTGGCCCGATGGCGAGGCGGAATATTTCCGTGGTGAAGTGGAAGGCACGCTCGTCTGGCCACCGCGCGGCAAT
ATCGGTTTCGGTTACGATCCGGTGTTTCTGCCCGATGGATACGGGAAAACCTTCGGCGAAATGACGGCGGAAGAAAAGCA
TGGCTGGAAGCCGGGTGACGCCAGCGCGCTGTCGCACCGGGCCCGCGCCTTCAAGCTTTTTGCCGAAAAGGCACTCAACG
TGGTATCGGCTCCGGCAGAATGA

Upstream 100 bases:

>100_bases
AGGCCGATTTCGATTGGCCCAATGGCGCACATTCGATTTATTTCCGCGATCCGTCCGGCAATTCGCTGGAGATTGCCGAA
CCCAAACTGTGGAATTGAAA

Downstream 100 bases:

>100_bases
ACAAGCTGTTTCCCCCTTTGCAGGCCAAAAATGCTGCCAGCACCTATCCCGTCATGCATGCTGATGGGGAAACCGCCTTT
GGCATTTATGTGCACTGGCC

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRMLEKGKLIVASHNAGKLREFDGLIGPFGFEVSSVAALGLPEPDETGTTFEENAYIKALAAAKATGFPALSDDSGLMVD
ALDGEPGVYTANWAETEDGKRDFDMAMQKVENLLQEKGATTPDKRKARFVSVICLAWPDGEAEYFRGEVEGTLVWPPRGN
IGFGYDPVFLPDGYGKTFGEMTAEEKHGWKPGDASALSHRARAFKLFAEKALNVVSAPAE

Sequences:

>Translated_220_residues
MRMLEKGKLIVASHNAGKLREFDGLIGPFGFEVSSVAALGLPEPDETGTTFEENAYIKALAAAKATGFPALSDDSGLMVD
ALDGEPGVYTANWAETEDGKRDFDMAMQKVENLLQEKGATTPDKRKARFVSVICLAWPDGEAEYFRGEVEGTLVWPPRGN
IGFGYDPVFLPDGYGKTFGEMTAEEKHGWKPGDASALSHRARAFKLFAEKALNVVSAPAE
>Mature_220_residues
MRMLEKGKLIVASHNAGKLREFDGLIGPFGFEVSSVAALGLPEPDETGTTFEENAYIKALAAAKATGFPALSDDSGLMVD
ALDGEPGVYTANWAETEDGKRDFDMAMQKVENLLQEKGATTPDKRKARFVSVICLAWPDGEAEYFRGEVEGTLVWPPRGN
IGFGYDPVFLPDGYGKTFGEMTAEEKHGWKPGDASALSHRARAFKLFAEKALNVVSAPAE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=208, Percent_Identity=38.4615384615385, Blast_Score=131, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6322529, Length=215, Percent_Identity=28.3720930232558, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_BRUME (P64305)

Other databases:

- EMBL:   AE008917
- PIR:   AF3473
- RefSeq:   NP_540689.1
- ProteinModelPortal:   P64305
- SMR:   P64305
- GeneID:   1197483
- GenomeReviews:   AE008917_GR
- KEGG:   bme:BMEI1772
- HOGENOM:   HBG697237
- OMA:   VYTADWA
- PhylomeDB:   P64305
- ProtClustDB:   PRK00120
- BioCyc:   BMEL224914:BMEI1772-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 23795; Mature: 23795

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMLEKGKLIVASHNAGKLREFDGLIGPFGFEVSSVAALGLPEPDETGTTFEENAYIKAL
CCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCHHHEEECCCCCCCCCCCEECCCHHHHHH
AAAKATGFPALSDDSGLMVDALDGEPGVYTANWAETEDGKRDFDMAMQKVENLLQEKGAT
HHHHHCCCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
TPDKRKARFVSVICLAWPDGEAEYFRGEVEGTLVWPPRGNIGFGYDPVFLPDGYGKTFGE
CCCHHHHEEEEEEEEECCCCCHHHEECCCCEEEEECCCCCCCCCCCCEECCCCCCCHHHH
MTAEEKHGWKPGDASALSHRARAFKLFAEKALNVVSAPAE
HCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRMLEKGKLIVASHNAGKLREFDGLIGPFGFEVSSVAALGLPEPDETGTTFEENAYIKAL
CCCCCCCCEEEEECCCCCHHHHCCCCCCCCCCHHHEEECCCCCCCCCCCEECCCHHHHHH
AAAKATGFPALSDDSGLMVDALDGEPGVYTANWAETEDGKRDFDMAMQKVENLLQEKGAT
HHHHHCCCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
TPDKRKARFVSVICLAWPDGEAEYFRGEVEGTLVWPPRGNIGFGYDPVFLPDGYGKTFGE
CCCHHHHEEEEEEEEECCCCCHHHEECCCCEEEEECCCCCCCCCCCCEECCCCCCCHHHH
MTAEEKHGWKPGDASALSHRARAFKLFAEKALNVVSAPAE
HCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688