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The map label for this gene is actR [H]

Identifier: 225851672

GI number: 225851672

Start: 151496

End: 152059

Strand: Direct

Name: actR [H]

Synonym: BMEA_A0143

Alternate gene names: 225851672

Gene position: 151496-152059 (Clockwise)

Preceding gene: 225851671

Following gene: 225851674

Centisome position: 7.13

GC content: 60.46

Gene sequence:

>564_bases
ATGGAAGACTTGAAGCAGGAAGACACCGAAGCCATAGGCAACGATCCCACCCTCCTTCTGGTTGATGACGACAAACCATT
CTTGCAGCGCCTGGCGCGTGCGATGGAAAGCCGGGGATTTCAGGTCACGACCGCTGAATCGGTTGAGGAAGGAATCGCCG
CCGTCAAGACATCTGCCCCCGCTTATGCGGTGGTGGACATGCGGCTTGGCGATGGCAACGGTCTCAATATCATCGAGGCG
ATCCGCTCGCGCCGTGCCGATACGCGCGCTATCGTTCTCACCGGATATGGCAATATCGCAACTGCCGTGAATGCCGTTAA
GCTCGGCGCCATCGACTATCTGTCGAAGCCCGCCGATGCGGATGAGGTGTTCGCCGCGCTCACCCGCCGCCCCGGCGAAA
AGGTTGCGCCGCCGGAAAATCCCATGTCTGCCGACCGGGTTCGCTGGGAGCATATCCAGCGTGTCTATGAAATGTGCGAG
CGCAATGTTTCCGAGACGGCACGCCGCCTCAATATGCATCGCCGCACTTTGCAACGCATCCTCGCCAAGCGCGCGCCGCG
CTGA

Upstream 100 bases:

>100_bases
ATGAAAATGGCCGTGAAATTGCTTTAATAATTCAATGGCTATTTGACTTTTTGACGCAGGAATATCAATAAGGGGCACGA
TTACAGGCAGGAAGCACCCG

Downstream 100 bases:

>100_bases
GATAGTCAATCGATTTCGGTGCCGGGTACGTCCAGCCCGGCAAGCTCGGCGGCCATGAGGCGGGCGGCCCCCGCACGGGC
AAAGCGCAGCATCAGCGCCT

Product: photosynthetic apparatus regulatory protein regA

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MEDLKQEDTEAIGNDPTLLLVDDDKPFLQRLARAMESRGFQVTTAESVEEGIAAVKTSAPAYAVVDMRLGDGNGLNIIEA
IRSRRADTRAIVLTGYGNIATAVNAVKLGAIDYLSKPADADEVFAALTRRPGEKVAPPENPMSADRVRWEHIQRVYEMCE
RNVSETARRLNMHRRTLQRILAKRAPR

Sequences:

>Translated_187_residues
MEDLKQEDTEAIGNDPTLLLVDDDKPFLQRLARAMESRGFQVTTAESVEEGIAAVKTSAPAYAVVDMRLGDGNGLNIIEA
IRSRRADTRAIVLTGYGNIATAVNAVKLGAIDYLSKPADADEVFAALTRRPGEKVAPPENPMSADRVRWEHIQRVYEMCE
RNVSETARRLNMHRRTLQRILAKRAPR
>Mature_187_residues
MEDLKQEDTEAIGNDPTLLLVDDDKPFLQRLARAMESRGFQVTTAESVEEGIAAVKTSAPAYAVVDMRLGDGNGLNIIEA
IRSRRADTRAIVLTGYGNIATAVNAVKLGAIDYLSKPADADEVFAALTRRPGEKVAPPENPMSADRVRWEHIQRVYEMCE
RNVSETARRLNMHRRTLQRILAKRAPR

Specific function: Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response [H]

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=33.6363636363636, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1788905, Length=110, Percent_Identity=33.6363636363636, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=30.188679245283, Blast_Score=64, Evalue=4e-12,
Organism=Escherichia coli, GI1790437, Length=112, Percent_Identity=29.4642857142857, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20787; Mature: 20787

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDLKQEDTEAIGNDPTLLLVDDDKPFLQRLARAMESRGFQVTTAESVEEGIAAVKTSAP
CCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCC
AYAVVDMRLGDGNGLNIIEAIRSRRADTRAIVLTGYGNIATAVNAVKLGAIDYLSKPADA
CEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCH
DEVFAALTRRPGEKVAPPENPMSADRVRWEHIQRVYEMCERNVSETARRLNMHRRTLQRI
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LAKRAPR
HHHCCCC
>Mature Secondary Structure
MEDLKQEDTEAIGNDPTLLLVDDDKPFLQRLARAMESRGFQVTTAESVEEGIAAVKTSAP
CCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCC
AYAVVDMRLGDGNGLNIIEAIRSRRADTRAIVLTGYGNIATAVNAVKLGAIDYLSKPADA
CEEEEEEEECCCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCH
DEVFAALTRRPGEKVAPPENPMSADRVRWEHIQRVYEMCERNVSETARRLNMHRRTLQRI
HHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LAKRAPR
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]