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The map label for this gene is pbpG [H]

Identifier: 225851657

GI number: 225851657

Start: 127916

End: 130207

Strand: Reverse

Name: pbpG [H]

Synonym: BMEA_A0124

Alternate gene names: 225851657

Gene position: 130207-127916 (Counterclockwise)

Preceding gene: 225851658

Following gene: 225851656

Centisome position: 6.13

GC content: 59.99

Gene sequence:

>2292_bases
ATGGCATCGCGAGACGACAGGAACAGACGCATCGAACCTTCCTTCGGTGGGGAAGAGAAGCGGGAAGATGAGGTCTTTCA
GGTCGATGAGGAGGATCGCATGGCTCGCTCGCAACAGCGCAGGCAAAAGCAATCCGCAGATCGTGCTCCCCGCTCTTCGC
GGGGCGGTAAAAGAAAGCAACGCGGCTTTTTCGGTTTTCTGCGCCGTTCGATCTACTGGTTTCTCGTGCTGGGCCTTTGG
GGCGGCATCGCCTTTGCTGGCCTTCTGGTCTATTTCGCGGCCAAGATGCCGCCGACGACCGCCTGGGCCATTCCTGACAG
GCCACCCAATGTGCGCATTGTCGATGTGAACAGCAATCTCATCGCCAACCGTGGCACGACGGGCGGCGAGGCCGTGAGCC
TGCATGAAATGTCGCCCTATATTCCCCAGGCCGTTATCGCCATTGAGGACCGCCGCTTCAATTCGCATTTCGGTATCGAC
CCGATCGGGCTTGCGCGCGCTATCGTAACCAATGTGGTTTCGGGCCGCGCGGTGCAGGGCGGCTCCACGCTGACACAGCA
GCTTGCCAAGAATCTCTTTCTTTCGCCTGACCGCACGCTGGAGCGCAAGGTGCAGGAAGTGATGCTCGCCCTTTGGCTGG
AGCATAAATATACCAAGGACCAGATATTGGAGATGTATCTGAACCGGGTTTATCTGGGTTCGGGCGCTTTCGGCGTCGAT
GCGGCATCGCGGCGCTATTTCAACAAATCGGCCAAGGACGTGAACCTGATGGAAGCGGCAACGCTTGCAGGGCTCCTGAA
AGCGCCTTCGCGCCTCTCCCCTGCCCGCGACCCGGAAGCCGCCGCAGCGCGCGCCAGGCTGGTGCTGGGCGCCATGCGCG
AGAAAGGCATGATCGACGACAGGCAGGTGGCGATTGCCGAAAGCGAACCACCGACGCGCGCGCCTTCCTACTGGCAGGGT
TCGGAAAACTATGTGGCCGACAAGGTTGTCGCCGAATTGCCCGAACTGATCGGCGAAGCAAAGGATGACATCATCGTCCA
GACGACCATCGATCTTAACCTCCAGCGCGCTGGCGAAGAGGCGATCAAGGATCAGATCGAGCAGAACGGCAAAAAGATGA
ATGCGAGCCAGGGCGCGCTTGTTTCCATCGATAATACGGGCGCGGTGCGCGCCATGGTGGGCGGGGTGGACTATGCGGCC
AGCCAGTTTGACCGCGTGACCGATGCGCATCGCCAACCGGCTTCCTCGTTCAAGCCCTTTGTCTATCTTTCTGCGCTGGA
ACAGGGCCGGACACCGGATTCCGTGCGCAACGACGCACCTGTGCGCATCGGCAAATGGACACCGAGTAATGATAACGGCA
AGTATATGGGGCCAGTGACGCTCGCCACCGCACTTTCCCATTCGCTGAACTCGGTCGCAGCCCAGCTTGTGATGGAAGTC
GGCCCCCAAACCGTGATCGACACGGCCCACCGCCTCGGTGTGCAGTCGAAGCTTGAACCCAATGCTTCGCTGGCGCTAGG
CACGTCGGAAGTGACACTTCTTGAATTAACCGACGCCTATGTTCCCTTCGCCAATGGCGGCTATCGCGCGCCGGTCTATT
TCATTACCAAGGTGACGGATTCCGATGGAAACGTGCTTTACCAGAAGGAAGATGGTGTCGGCCCGCGCGTGATCGACGAG
CGCAATGTCGGCATGATGAACGCCATGCTGCGCCGCACCGTGGAAGATGGCACCGCCAAACGCGCCGCCTTCGGCTGGCC
GGCCGCAGGCAAAACCGGCACTAGCCAGAATTTCCGCGATGCCTGGTTCATCGGCTACACAGCCAATCTTACGACCGGCG
TTTGGTTCGGCAATGACGACGGCAAGGGCATGAAGCGCGTTTTTGGCGCAACACTTCCCGTGGCGGCCTGGAAAAGCTTC
ATGAAGGAAGCACATAAGGGTGTTCCCATCGCCGAGCTTCCCGGCCATTACGATATCCAGAACGTGCTGCCCGGCGGCAG
CGACGGCATAGACCCCAATGCGCCTTATGATCCCGGCATGATGCAGCAGGATAATTATGGCAACCAGCCGATGGCAGGCA
CCGGCGACGATGGCTACTGGCCACCGGCGCCGGATTTGCCCGGCCGAAGCGGTATCCAGCAGGGCGAAACCGGACAGCCC
CTTGCCTCTTCCGCCAGGAATAACGGCGATTACCGGCCCATGCCTGCGGGCAATGTGGGCGAACAGCCGCAAGCCCAGCC
TGCGAGAAAATCCACCACCCTGCTCGATATCATCATGGGTAATTCACAGTAA

Upstream 100 bases:

>100_bases
CTTCAGGGCGATAGCGAACGGTGGGGCACCGCTCTGTGCGAGCAGATCGAAACACGCTCCGGCATGAAAAACAGGCGCGT
GGGGCGCGGATCAGGCAGAC

Downstream 100 bases:

>100_bases
AAACAGGAGGGACTGGCAAGCGGCCAGTCCCTTCATGGTGCTTTCATTCCCTTGCCATGCTGAATCCCCCTCGAAATCTT
GAGCGGCATGGTCTATTCAA

Product: 1A family penicillin-binding protein

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 763; Mature: 762

Protein sequence:

>763_residues
MASRDDRNRRIEPSFGGEEKREDEVFQVDEEDRMARSQQRRQKQSADRAPRSSRGGKRKQRGFFGFLRRSIYWFLVLGLW
GGIAFAGLLVYFAAKMPPTTAWAIPDRPPNVRIVDVNSNLIANRGTTGGEAVSLHEMSPYIPQAVIAIEDRRFNSHFGID
PIGLARAIVTNVVSGRAVQGGSTLTQQLAKNLFLSPDRTLERKVQEVMLALWLEHKYTKDQILEMYLNRVYLGSGAFGVD
AASRRYFNKSAKDVNLMEAATLAGLLKAPSRLSPARDPEAAAARARLVLGAMREKGMIDDRQVAIAESEPPTRAPSYWQG
SENYVADKVVAELPELIGEAKDDIIVQTTIDLNLQRAGEEAIKDQIEQNGKKMNASQGALVSIDNTGAVRAMVGGVDYAA
SQFDRVTDAHRQPASSFKPFVYLSALEQGRTPDSVRNDAPVRIGKWTPSNDNGKYMGPVTLATALSHSLNSVAAQLVMEV
GPQTVIDTAHRLGVQSKLEPNASLALGTSEVTLLELTDAYVPFANGGYRAPVYFITKVTDSDGNVLYQKEDGVGPRVIDE
RNVGMMNAMLRRTVEDGTAKRAAFGWPAAGKTGTSQNFRDAWFIGYTANLTTGVWFGNDDGKGMKRVFGATLPVAAWKSF
MKEAHKGVPIAELPGHYDIQNVLPGGSDGIDPNAPYDPGMMQQDNYGNQPMAGTGDDGYWPPAPDLPGRSGIQQGETGQP
LASSARNNGDYRPMPAGNVGEQPQAQPARKSTTLLDIIMGNSQ

Sequences:

>Translated_763_residues
MASRDDRNRRIEPSFGGEEKREDEVFQVDEEDRMARSQQRRQKQSADRAPRSSRGGKRKQRGFFGFLRRSIYWFLVLGLW
GGIAFAGLLVYFAAKMPPTTAWAIPDRPPNVRIVDVNSNLIANRGTTGGEAVSLHEMSPYIPQAVIAIEDRRFNSHFGID
PIGLARAIVTNVVSGRAVQGGSTLTQQLAKNLFLSPDRTLERKVQEVMLALWLEHKYTKDQILEMYLNRVYLGSGAFGVD
AASRRYFNKSAKDVNLMEAATLAGLLKAPSRLSPARDPEAAAARARLVLGAMREKGMIDDRQVAIAESEPPTRAPSYWQG
SENYVADKVVAELPELIGEAKDDIIVQTTIDLNLQRAGEEAIKDQIEQNGKKMNASQGALVSIDNTGAVRAMVGGVDYAA
SQFDRVTDAHRQPASSFKPFVYLSALEQGRTPDSVRNDAPVRIGKWTPSNDNGKYMGPVTLATALSHSLNSVAAQLVMEV
GPQTVIDTAHRLGVQSKLEPNASLALGTSEVTLLELTDAYVPFANGGYRAPVYFITKVTDSDGNVLYQKEDGVGPRVIDE
RNVGMMNAMLRRTVEDGTAKRAAFGWPAAGKTGTSQNFRDAWFIGYTANLTTGVWFGNDDGKGMKRVFGATLPVAAWKSF
MKEAHKGVPIAELPGHYDIQNVLPGGSDGIDPNAPYDPGMMQQDNYGNQPMAGTGDDGYWPPAPDLPGRSGIQQGETGQP
LASSARNNGDYRPMPAGNVGEQPQAQPARKSTTLLDIIMGNSQ
>Mature_762_residues
ASRDDRNRRIEPSFGGEEKREDEVFQVDEEDRMARSQQRRQKQSADRAPRSSRGGKRKQRGFFGFLRRSIYWFLVLGLWG
GIAFAGLLVYFAAKMPPTTAWAIPDRPPNVRIVDVNSNLIANRGTTGGEAVSLHEMSPYIPQAVIAIEDRRFNSHFGIDP
IGLARAIVTNVVSGRAVQGGSTLTQQLAKNLFLSPDRTLERKVQEVMLALWLEHKYTKDQILEMYLNRVYLGSGAFGVDA
ASRRYFNKSAKDVNLMEAATLAGLLKAPSRLSPARDPEAAAARARLVLGAMREKGMIDDRQVAIAESEPPTRAPSYWQGS
ENYVADKVVAELPELIGEAKDDIIVQTTIDLNLQRAGEEAIKDQIEQNGKKMNASQGALVSIDNTGAVRAMVGGVDYAAS
QFDRVTDAHRQPASSFKPFVYLSALEQGRTPDSVRNDAPVRIGKWTPSNDNGKYMGPVTLATALSHSLNSVAAQLVMEVG
PQTVIDTAHRLGVQSKLEPNASLALGTSEVTLLELTDAYVPFANGGYRAPVYFITKVTDSDGNVLYQKEDGVGPRVIDER
NVGMMNAMLRRTVEDGTAKRAAFGWPAAGKTGTSQNFRDAWFIGYTANLTTGVWFGNDDGKGMKRVFGATLPVAAWKSFM
KEAHKGVPIAELPGHYDIQNVLPGGSDGIDPNAPYDPGMMQQDNYGNQPMAGTGDDGYWPPAPDLPGRSGIQQGETGQPL
ASSARNNGDYRPMPAGNVGEQPQAQPARKSTTLLDIIMGNSQ

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=585, Percent_Identity=31.965811965812, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI1788867, Length=581, Percent_Identity=32.8743545611015, Blast_Score=222, Evalue=7e-59,
Organism=Escherichia coli, GI87082258, Length=307, Percent_Identity=37.1335504885993, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI1789601, Length=236, Percent_Identity=33.8983050847458, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 83120; Mature: 82988

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRDDRNRRIEPSFGGEEKREDEVFQVDEEDRMARSQQRRQKQSADRAPRSSRGGKRKQ
CCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
RGFFGFLRRSIYWFLVLGLWGGIAFAGLLVYFAAKMPPTTAWAIPDRPPNVRIVDVNSNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEECCCCE
IANRGTTGGEAVSLHEMSPYIPQAVIAIEDRRFNSHFGIDPIGLARAIVTNVVSGRAVQG
EECCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEECC
GSTLTQQLAKNLFLSPDRTLERKVQEVMLALWLEHKYTKDQILEMYLNRVYLGSGAFGVD
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCC
AASRRYFNKSAKDVNLMEAATLAGLLKAPSRLSPARDPEAAAARARLVLGAMREKGMIDD
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
RQVAIAESEPPTRAPSYWQGSENYVADKVVAELPELIGEAKDDIIVQTTIDLNLQRAGEE
CEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHH
AIKDQIEQNGKKMNASQGALVSIDNTGAVRAMVGGVDYAASQFDRVTDAHRQPASSFKPF
HHHHHHHHCCCEECCCCCCEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHCCCHHHCCCE
VYLSALEQGRTPDSVRNDAPVRIGKWTPSNDNGKYMGPVTLATALSHSLNSVAAQLVMEV
EEEEHHHCCCCCCHHCCCCCEEEECCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHH
GPQTVIDTAHRLGVQSKLEPNASLALGTSEVTLLELTDAYVPFANGGYRAPVYFITKVTD
CCHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEEC
SDGNVLYQKEDGVGPRVIDERNVGMMNAMLRRTVEDGTAKRAAFGWPAAGKTGTSQNFRD
CCCCEEEEECCCCCCCEECCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCC
AWFIGYTANLTTGVWFGNDDGKGMKRVFGATLPVAAWKSFMKEAHKGVPIAELPGHYDIQ
EEEEEEECCCEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCHH
NVLPGGSDGIDPNAPYDPGMMQQDNYGNQPMAGTGDDGYWPPAPDLPGRSGIQQGETGQP
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
LASSARNNGDYRPMPAGNVGEQPQAQPARKSTTLLDIIMGNSQ
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCEEEEEEECCCC
>Mature Secondary Structure 
ASRDDRNRRIEPSFGGEEKREDEVFQVDEEDRMARSQQRRQKQSADRAPRSSRGGKRKQ
CCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
RGFFGFLRRSIYWFLVLGLWGGIAFAGLLVYFAAKMPPTTAWAIPDRPPNVRIVDVNSNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEECCCCE
IANRGTTGGEAVSLHEMSPYIPQAVIAIEDRRFNSHFGIDPIGLARAIVTNVVSGRAVQG
EECCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEECC
GSTLTQQLAKNLFLSPDRTLERKVQEVMLALWLEHKYTKDQILEMYLNRVYLGSGAFGVD
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCCCCC
AASRRYFNKSAKDVNLMEAATLAGLLKAPSRLSPARDPEAAAARARLVLGAMREKGMIDD
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
RQVAIAESEPPTRAPSYWQGSENYVADKVVAELPELIGEAKDDIIVQTTIDLNLQRAGEE
CEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHH
AIKDQIEQNGKKMNASQGALVSIDNTGAVRAMVGGVDYAASQFDRVTDAHRQPASSFKPF
HHHHHHHHCCCEECCCCCCEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHCCCHHHCCCE
VYLSALEQGRTPDSVRNDAPVRIGKWTPSNDNGKYMGPVTLATALSHSLNSVAAQLVMEV
EEEEHHHCCCCCCHHCCCCCEEEECCCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHH
GPQTVIDTAHRLGVQSKLEPNASLALGTSEVTLLELTDAYVPFANGGYRAPVYFITKVTD
CCHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCEEEEEEEEC
SDGNVLYQKEDGVGPRVIDERNVGMMNAMLRRTVEDGTAKRAAFGWPAAGKTGTSQNFRD
CCCCEEEEECCCCCCCEECCCCCHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCC
AWFIGYTANLTTGVWFGNDDGKGMKRVFGATLPVAAWKSFMKEAHKGVPIAELPGHYDIQ
EEEEEEECCCEEEEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCHH
NVLPGGSDGIDPNAPYDPGMMQQDNYGNQPMAGTGDDGYWPPAPDLPGRSGIQQGETGQP
HCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
LASSARNNGDYRPMPAGNVGEQPQAQPARKSTTLLDIIMGNSQ
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]