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The map label for this gene is cysW [H]

Identifier: 225851649

GI number: 225851649

Start: 111744

End: 112610

Strand: Direct

Name: cysW [H]

Synonym: BMEA_A0116

Alternate gene names: 225851649

Gene position: 111744-112610 (Clockwise)

Preceding gene: 225851648

Following gene: 225851650

Centisome position: 5.26

GC content: 59.05

Gene sequence:

>867_bases
ATGGCGCATGAAGCCGCTTGCACCCGTCATGGCGCCGTGACCGAAAGCCCGCCGGTGCGTATTGCGCTGATTGCGCTGGC
GCTTGCCTTTCTGGCGCTCTTTCTCATCCTCCCGGTGGTCGCCGTTTTCGTGGAAGCCTTCCGCAAGGGAATGTCCGAAT
ATATCGCCGCGCTGGTGGAGCCGGATGCGTGGGCCGCCATCAAACTGACATTGACGGTCGCCGCCATTGCCGTGCCGCTC
AATGTCGTCTTCGGAATTGCGGCTGCATGGGCTATCGCCAAGTTCGAATTCAAGGGCAAGGCGCTTTTGACCACACTGAT
CGACCTGCCGTTTTCGGTATCGCCGGTCATATCGGGCCTCGTCTTCGTGCTGCTTTTTTCCAGCCACAGCCTGCTCGGCC
CATGGCTGTCGCGCCATGGCATCGAAATTCTCTTTGCCGTGCCGGGCATTGTGCTGGCAACAGTGTTCGTGACCTTTCCT
TTCGTGGCGCGTGAGCTGATCCCGCTCATGCAGGAACAGGGAACGGGTGATGAGGAAGCGGCGATCTCGCTTGGCGCCAG
TGGCTGGCAGGCCTTCCGCTATGTCACATTGCCCAACATCAAATGGGGCCTGCTTTACGGCGTCCTGCTTTGCAATGCGC
GCGCAATGGGCGAGTTCGGCGCGGTTTCGGTCGTGTCTGGCCATATTCGCGGCCTCACCAATACGATGCCGCTTCATGTC
GAAATCCTTTATAATGAGTATAATTTTGTCGGAGCCTTCGCGGTGGCGTCGTTGCTTGCCTTTCTCGCGCTGCTGACACT
GGCTATCAAGGCCGTGCTGGAATTGCGCTATGGCGACGAACTGGCAGGCAGCGGAAACGGGCATTGA

Upstream 100 bases:

>100_bases
GCGGGCGCGACGGCGCTGGCCACGGTGATGCTGGCGCTTTCTTTCGCGATGCTTCTGTTCATCAATCTCATTCAGACACG
CATACGGAGGAAATACGGCC

Downstream 100 bases:

>100_bases
ATTTGCGGGAGCATCGATGCTCCCGTTCGGGCGCAGCCGTGATGGCGGCGCAATGAAACAAGCATGGCCGCGCAGGCGGC
AGGGGAAAGGATTGGGAATG

Product: sulfate ABC transporter permease CysW

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MAHEAACTRHGAVTESPPVRIALIALALAFLALFLILPVVAVFVEAFRKGMSEYIAALVEPDAWAAIKLTLTVAAIAVPL
NVVFGIAAAWAIAKFEFKGKALLTTLIDLPFSVSPVISGLVFVLLFSSHSLLGPWLSRHGIEILFAVPGIVLATVFVTFP
FVARELIPLMQEQGTGDEEAAISLGASGWQAFRYVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLTNTMPLHV
EILYNEYNFVGAFAVASLLAFLALLTLAIKAVLELRYGDELAGSGNGH

Sequences:

>Translated_288_residues
MAHEAACTRHGAVTESPPVRIALIALALAFLALFLILPVVAVFVEAFRKGMSEYIAALVEPDAWAAIKLTLTVAAIAVPL
NVVFGIAAAWAIAKFEFKGKALLTTLIDLPFSVSPVISGLVFVLLFSSHSLLGPWLSRHGIEILFAVPGIVLATVFVTFP
FVARELIPLMQEQGTGDEEAAISLGASGWQAFRYVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLTNTMPLHV
EILYNEYNFVGAFAVASLLAFLALLTLAIKAVLELRYGDELAGSGNGH
>Mature_287_residues
AHEAACTRHGAVTESPPVRIALIALALAFLALFLILPVVAVFVEAFRKGMSEYIAALVEPDAWAAIKLTLTVAAIAVPLN
VVFGIAAAWAIAKFEFKGKALLTTLIDLPFSVSPVISGLVFVLLFSSHSLLGPWLSRHGIEILFAVPGIVLATVFVTFPF
VARELIPLMQEQGTGDEEAAISLGASGWQAFRYVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLTNTMPLHVE
ILYNEYNFVGAFAVASLLAFLALLTLAIKAVLELRYGDELAGSGNGH

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=258, Percent_Identity=53.1007751937985, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI1788764, Length=232, Percent_Identity=36.2068965517241, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1786980, Length=181, Percent_Identity=34.8066298342541, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30702; Mature: 30570

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHEAACTRHGAVTESPPVRIALIALALAFLALFLILPVVAVFVEAFRKGMSEYIAALVE
CCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PDAWAAIKLTLTVAAIAVPLNVVFGIAAAWAIAKFEFKGKALLTTLIDLPFSVSPVISGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHH
VFVLLFSSHSLLGPWLSRHGIEILFAVPGIVLATVFVTFPFVARELIPLMQEQGTGDEEA
HHHHHHHCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AISLGASGWQAFRYVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLTNTMPLHV
HEECCCCCHHHEEEEECCCCHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHCCCCCCCEEE
EILYNEYNFVGAFAVASLLAFLALLTLAIKAVLELRYGDELAGSGNGH
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AHEAACTRHGAVTESPPVRIALIALALAFLALFLILPVVAVFVEAFRKGMSEYIAALVE
CCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PDAWAAIKLTLTVAAIAVPLNVVFGIAAAWAIAKFEFKGKALLTTLIDLPFSVSPVISGL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHH
VFVLLFSSHSLLGPWLSRHGIEILFAVPGIVLATVFVTFPFVARELIPLMQEQGTGDEEA
HHHHHHHCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AISLGASGWQAFRYVTLPNIKWGLLYGVLLCNARAMGEFGAVSVVSGHIRGLTNTMPLHV
HEECCCCCHHHEEEEECCCCHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHCCCCCCCEEE
EILYNEYNFVGAFAVASLLAFLALLTLAIKAVLELRYGDELAGSGNGH
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]