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The map label for this gene is dnaX [H]

Identifier: 225851577

GI number: 225851577

Start: 38731

End: 40539

Strand: Reverse

Name: dnaX [H]

Synonym: BMEA_A0034

Alternate gene names: 225851577

Gene position: 40539-38731 (Counterclockwise)

Preceding gene: 225851580

Following gene: 225851576

Centisome position: 1.91

GC content: 61.86

Gene sequence:

>1809_bases
ATGGACACACAATCCGCCGATGGCGCCTATCGCGTTCTAGCCCGCAAATATCGCCCGCAGAATTTCGATGATCTCATCGG
CCAGGAGCCGATGGTGCGCACGCTGCGCAATGCGTTCGAGACGGGCCGCATCGCACAGGCCTGGATGCTTACCGGCGTGC
GCGGGGTCGGCAAGACCACGACGGCACGTATTCTGGCGCGCGCGCTCAATTACAAGACCGATACGGTCGATCAGCCAACG
ATCGATCTTTCCACACCGGGCGAGCATTGCCAGGCGATCATGGAAGGCCGCCATGTCGATGTCATCGAGATGGACGCGGC
CTCGCATACAGGCATCGACGACATTCGCGAGATCATCGAGCAGGTCCGCTATCGCCCGGTTTCAGCGCGCTACAAAGTCT
ATATCATCGACGAAGTGCACATGCTTTCCACCGCCGCCTTCAACGGGTTGCTGAAGACGCTGGAAGAGCCGCCGCCGCAC
GTCAAGTTCATCTTCGCCACCACTGAAATCCGCAAGGTTCCGATCACGGTCCTGTCGCGCTGCCAGCGTTTCGATCTGCG
CCGCATCGAATCGGGCACGCTGGCGCAGCATCTGCGCCGCATCGCGGAAGCCGAAAAGATCGAGGTGGACGACGCATCGC
TCGCCATGATCGCACGCGCGGGCGAAGGGTCTGCGCGTGATTCGCTGTCGATCTTCGATCAGGCGATTGCGCATGGTGCG
GGCAGCGTCACAGCGGAAGCCGTGCGTTCCATGCTGGGCCTTGCCGACCGTGCCCGTATCATCGACCTGTTTGAAATGCT
GATGCGCGGCGATGTGGCTGGCGCGCTCACCGAATTTCGCGCGCAATATGATGTGGGCGCCGACCCTTCGGTGGTGCTGA
CCGATCTTGCCGATTTCAACCATCTGGTGACGCGCCTGCGTTTCACGCCGGATGTGGCCGAGGATGTGTCGCTGTCGGAA
GATGAGCGCGTGCGCGGACGCGAATTCGCACAGACACTTTCCATACGCGCGCTCTCACGCACCTGGCAGATGCTGCTCAA
GGGCATTGCGGAAGTGGATACGGCGACGAGGCCGGTTCAGGCGGCTGAAATGCTTTTGATCCGCCTTGCCCATGCTGCCG
ACCTGCCAACGCTGGACGAGGCGATCCGTGGTCTCGACAATGGTTCGGTTTCTGCACCGCGCCCGCAGCCTTCCGCAACA
CCGCGGCCAAATGGCGGCAGTGCGCCGCAAGCGCATGGGGCCGCCGATGCCGTCGGTTCTTCAGCACTTGCACCGGCAGC
CGGTGGACCGGCCACGGCCATGCGCATTGTGGAAACGCCGCCGATCCAGGTTTCCGCACCAAAACCATCTGAAGCGGCGC
CGCAGCCTTCCGTACCGATCAACAGCTTGCAGGATATCGTTGCGCTTGCCGATAAATATCGCGACATGCAGTTCAAGATT
CTGGTCAAAAACTGTGTGCGTCCGGCATCGATTGCGCCGGGGCGGCTGGAAATCGGCTTGACGGACGATGCGCCGAAATC
GCTGCCGAGTGATATTGCACAGCATCTTCTGAACTGGACCGGCATTCGCTGGGTGGTGACGGTGGCGCGCGACGTTGCGG
GCCAGACCATTGCCGAAGCGGAAGCCGAACGCCGCGACAATCTGGTGACGGACGCCCGCGCCGACCCCGATGTGGCGGCC
ATTCTCGCGGCTTTTCCCGGCGCGAAGATCATAGACGTACGCATTGCTGTGCCGGATAAGAGCAAAGACGAGGATATCGA
CCTCGACGCCGTGGCGGAAGTGCCGGACGTTCTGCCTGAAGACGACTGA

Upstream 100 bases:

>100_bases
CCGATGACTGTTGATGGATTGCCTCTTTGGTTGACGGCAATCACAGGACCGGTTCAAACTGGAAACAGAGAAAGAAGCGA
ATGGAGAACGGAAGGGTCGC

Downstream 100 bases:

>100_bases
ATGACGCAATGATGGAGTGAACCCATGCGTGACATGATGGGCATGATGAAACAGGCGAAGGAATTGCAGGCCAAGATGAA
GGCCATGCAGGACGAAATCG

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 602

Protein sequence:

>602_residues
MDTQSADGAYRVLARKYRPQNFDDLIGQEPMVRTLRNAFETGRIAQAWMLTGVRGVGKTTTARILARALNYKTDTVDQPT
IDLSTPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTAAFNGLLKTLEEPPPH
VKFIFATTEIRKVPITVLSRCQRFDLRRIESGTLAQHLRRIAEAEKIEVDDASLAMIARAGEGSARDSLSIFDQAIAHGA
GSVTAEAVRSMLGLADRARIIDLFEMLMRGDVAGALTEFRAQYDVGADPSVVLTDLADFNHLVTRLRFTPDVAEDVSLSE
DERVRGREFAQTLSIRALSRTWQMLLKGIAEVDTATRPVQAAEMLLIRLAHAADLPTLDEAIRGLDNGSVSAPRPQPSAT
PRPNGGSAPQAHGAADAVGSSALAPAAGGPATAMRIVETPPIQVSAPKPSEAAPQPSVPINSLQDIVALADKYRDMQFKI
LVKNCVRPASIAPGRLEIGLTDDAPKSLPSDIAQHLLNWTGIRWVVTVARDVAGQTIAEAEAERRDNLVTDARADPDVAA
ILAAFPGAKIIDVRIAVPDKSKDEDIDLDAVAEVPDVLPEDD

Sequences:

>Translated_602_residues
MDTQSADGAYRVLARKYRPQNFDDLIGQEPMVRTLRNAFETGRIAQAWMLTGVRGVGKTTTARILARALNYKTDTVDQPT
IDLSTPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTAAFNGLLKTLEEPPPH
VKFIFATTEIRKVPITVLSRCQRFDLRRIESGTLAQHLRRIAEAEKIEVDDASLAMIARAGEGSARDSLSIFDQAIAHGA
GSVTAEAVRSMLGLADRARIIDLFEMLMRGDVAGALTEFRAQYDVGADPSVVLTDLADFNHLVTRLRFTPDVAEDVSLSE
DERVRGREFAQTLSIRALSRTWQMLLKGIAEVDTATRPVQAAEMLLIRLAHAADLPTLDEAIRGLDNGSVSAPRPQPSAT
PRPNGGSAPQAHGAADAVGSSALAPAAGGPATAMRIVETPPIQVSAPKPSEAAPQPSVPINSLQDIVALADKYRDMQFKI
LVKNCVRPASIAPGRLEIGLTDDAPKSLPSDIAQHLLNWTGIRWVVTVARDVAGQTIAEAEAERRDNLVTDARADPDVAA
ILAAFPGAKIIDVRIAVPDKSKDEDIDLDAVAEVPDVLPEDD
>Mature_602_residues
MDTQSADGAYRVLARKYRPQNFDDLIGQEPMVRTLRNAFETGRIAQAWMLTGVRGVGKTTTARILARALNYKTDTVDQPT
IDLSTPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIEQVRYRPVSARYKVYIIDEVHMLSTAAFNGLLKTLEEPPPH
VKFIFATTEIRKVPITVLSRCQRFDLRRIESGTLAQHLRRIAEAEKIEVDDASLAMIARAGEGSARDSLSIFDQAIAHGA
GSVTAEAVRSMLGLADRARIIDLFEMLMRGDVAGALTEFRAQYDVGADPSVVLTDLADFNHLVTRLRFTPDVAEDVSLSE
DERVRGREFAQTLSIRALSRTWQMLLKGIAEVDTATRPVQAAEMLLIRLAHAADLPTLDEAIRGLDNGSVSAPRPQPSAT
PRPNGGSAPQAHGAADAVGSSALAPAAGGPATAMRIVETPPIQVSAPKPSEAAPQPSVPINSLQDIVALADKYRDMQFKI
LVKNCVRPASIAPGRLEIGLTDDAPKSLPSDIAQHLLNWTGIRWVVTVARDVAGQTIAEAEAERRDNLVTDARADPDVAA
ILAAFPGAKIIDVRIAVPDKSKDEDIDLDAVAEVPDVLPEDD

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=293, Percent_Identity=24.2320819112628, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI194306571, Length=296, Percent_Identity=23.9864864864865, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI194306567, Length=296, Percent_Identity=23.9864864864865, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI4506491, Length=319, Percent_Identity=22.884012539185, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI31881687, Length=319, Percent_Identity=22.884012539185, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1786676, Length=361, Percent_Identity=39.8891966759003, Blast_Score=266, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI17541988, Length=236, Percent_Identity=27.1186440677966, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17554730, Length=211, Percent_Identity=24.1706161137441, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322528, Length=275, Percent_Identity=23.2727272727273, Blast_Score=77, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6324478, Length=238, Percent_Identity=23.9495798319328, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324039, Length=224, Percent_Identity=23.2142857142857, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17647857, Length=287, Percent_Identity=24.7386759581882, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI18859927, Length=260, Percent_Identity=23.0769230769231, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19921076, Length=258, Percent_Identity=24.8062015503876, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 65251; Mature: 65251

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQSADGAYRVLARKYRPQNFDDLIGQEPMVRTLRNAFETGRIAQAWMLTGVRGVGKTT
CCCCCCCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHH
TARILARALNYKTDTVDQPTIDLSTPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIE
HHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
QVRYRPVSARYKVYIIDEVHMLSTAAFNGLLKTLEEPPPHVKFIFATTEIRKVPITVLSR
HHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHCHHHHHHH
CQRFDLRRIESGTLAQHLRRIAEAEKIEVDDASLAMIARAGEGSARDSLSIFDQAIAHGA
HHHHHHHHCCCCHHHHHHHHHHHHHHEECCCHHEEEEEECCCCCCCHHHHHHHHHHHCCC
GSVTAEAVRSMLGLADRARIIDLFEMLMRGDVAGALTEFRAQYDVGADPSVVLTDLADFN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHH
HLVTRLRFTPDVAEDVSLSEDERVRGREFAQTLSIRALSRTWQMLLKGIAEVDTATRPVQ
HHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AAEMLLIRLAHAADLPTLDEAIRGLDNGSVSAPRPQPSATPRPNGGSAPQAHGAADAVGS
HHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
SALAPAAGGPATAMRIVETPPIQVSAPKPSEAAPQPSVPINSLQDIVALADKYRDMQFKI
CCCCCCCCCCHHEEEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHH
LVKNCVRPASIAPGRLEIGLTDDAPKSLPSDIAQHLLNWTGIRWVVTVARDVAGQTIAEA
HHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHH
EAERRDNLVTDARADPDVAAILAAFPGAKIIDVRIAVPDKSKDEDIDLDAVAEVPDVLPE
HHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCC
DD
CC
>Mature Secondary Structure
MDTQSADGAYRVLARKYRPQNFDDLIGQEPMVRTLRNAFETGRIAQAWMLTGVRGVGKTT
CCCCCCCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHH
TARILARALNYKTDTVDQPTIDLSTPGEHCQAIMEGRHVDVIEMDAASHTGIDDIREIIE
HHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHH
QVRYRPVSARYKVYIIDEVHMLSTAAFNGLLKTLEEPPPHVKFIFATTEIRKVPITVLSR
HHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHCHHHHHHH
CQRFDLRRIESGTLAQHLRRIAEAEKIEVDDASLAMIARAGEGSARDSLSIFDQAIAHGA
HHHHHHHHCCCCHHHHHHHHHHHHHHEECCCHHEEEEEECCCCCCCHHHHHHHHHHHCCC
GSVTAEAVRSMLGLADRARIIDLFEMLMRGDVAGALTEFRAQYDVGADPSVVLTDLADFN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEHHHHHHHH
HLVTRLRFTPDVAEDVSLSEDERVRGREFAQTLSIRALSRTWQMLLKGIAEVDTATRPVQ
HHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
AAEMLLIRLAHAADLPTLDEAIRGLDNGSVSAPRPQPSATPRPNGGSAPQAHGAADAVGS
HHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
SALAPAAGGPATAMRIVETPPIQVSAPKPSEAAPQPSVPINSLQDIVALADKYRDMQFKI
CCCCCCCCCCHHEEEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHH
LVKNCVRPASIAPGRLEIGLTDDAPKSLPSDIAQHLLNWTGIRWVVTVARDVAGQTIAEA
HHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHH
EAERRDNLVTDARADPDVAAILAAFPGAKIIDVRIAVPDKSKDEDIDLDAVAEVPDVLPE
HHHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCC
DD
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]