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The map label for this gene is pheA [H]

Identifier: 225851580

GI number: 225851580

Start: 42202

End: 43065

Strand: Reverse

Name: pheA [H]

Synonym: BMEA_A0039

Alternate gene names: 225851580

Gene position: 43065-42202 (Counterclockwise)

Preceding gene: 225851581

Following gene: 225851577

Centisome position: 2.03

GC content: 58.56

Gene sequence:

>864_bases
ATGAAAACCAACAGGATTTCCTTCCAGGGTGAAGCAGGCGCAAACTCCGATACGGCGTGCCGCAACATGTTTCCCGATAT
GGAGCCTTTGCCGTGCCCGACTTTTGAGGATGCCTTCAATGCGGTTGAAACCGGCGCCGCAGACCTCGCGATGATCCCGA
TCGAGAACACGCTGGCCGGGCGCGTCGCCGATATTCATTATCTGCTACCGCTGGCCGACATGCACATTGTTGGCGAATAT
TTCCTGCCGATCCATTTCCAGCTTATGGTGCTTCCGGGTGTCCGGCGCGAGGAAATCAAGACGGTGCACAGCCATATCCA
CGCGCTCGGCCAGTGCCGCAACGTCATCCGCCAGAACGGCTGGAAGGGTGTGATTGCCGGTGACACGGCAGGGGCCGCGC
GCCTCGTCGCCGATGTGAAGGATCGCTCGATGGCGGCACTCGCGCCACGTCTTGCCGCCGATCTCTACGGCCTCGATATT
CTGGAAGAAAATGTCGAGGATTCCGAAAACAACGTCACCCGCTTCGTGGTCCTCTCCAAGAACAAGCAGTGGGCGGCGCG
GCCTGAAAACGACGAGCGCATTGTGACGACCTTCGTGTTCCGGGTGCGCAACGTGCCCGCCGCACTTTACAAGGCGCTGG
GCGGTTTCGCCACCAATGGCGTCAATATGACGAAGCTCGAAAGCTATCAGCTCGGCGGACGCTTCATCGCAACGCAGTTC
TATGCCGATATCGAGGGACACCCGGAAGAGCGTTCGGTGCAGCTTGCACTGGAAGAACTGCGCTTCTTCACCAAGGAAGT
GCGAATTCTGGGCGTTTACAAGGGAAGCGATATTCGCGGTACGCAGCTACTGGCTGCCGAATAA

Upstream 100 bases:

>100_bases
GGAACCATTTGACGCCGCACAAATGCGGCGTAAAAGATTCCTGTAGCACAGGGTAACTGACAGGCCGCCGATGAGCGGCA
TTTGAGAAAGCATGGGTACA

Downstream 100 bases:

>100_bases
TCAGCCTGCATCATAAGCCCAGGCCTTTATCAGATGGGTTGCGATGGCGCCGCATGGCGGCACCCGCAACCCATTTTCAT
GGGTACCTTCCAGCATGGTG

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT; MjPDT [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKTNRISFQGEAGANSDTACRNMFPDMEPLPCPTFEDAFNAVETGAADLAMIPIENTLAGRVADIHYLLPLADMHIVGEY
FLPIHFQLMVLPGVRREEIKTVHSHIHALGQCRNVIRQNGWKGVIAGDTAGAARLVADVKDRSMAALAPRLAADLYGLDI
LEENVEDSENNVTRFVVLSKNKQWAARPENDERIVTTFVFRVRNVPAALYKALGGFATNGVNMTKLESYQLGGRFIATQF
YADIEGHPEERSVQLALEELRFFTKEVRILGVYKGSDIRGTQLLAAE

Sequences:

>Translated_287_residues
MKTNRISFQGEAGANSDTACRNMFPDMEPLPCPTFEDAFNAVETGAADLAMIPIENTLAGRVADIHYLLPLADMHIVGEY
FLPIHFQLMVLPGVRREEIKTVHSHIHALGQCRNVIRQNGWKGVIAGDTAGAARLVADVKDRSMAALAPRLAADLYGLDI
LEENVEDSENNVTRFVVLSKNKQWAARPENDERIVTTFVFRVRNVPAALYKALGGFATNGVNMTKLESYQLGGRFIATQF
YADIEGHPEERSVQLALEELRFFTKEVRILGVYKGSDIRGTQLLAAE
>Mature_287_residues
MKTNRISFQGEAGANSDTACRNMFPDMEPLPCPTFEDAFNAVETGAADLAMIPIENTLAGRVADIHYLLPLADMHIVGEY
FLPIHFQLMVLPGVRREEIKTVHSHIHALGQCRNVIRQNGWKGVIAGDTAGAARLVADVKDRSMAALAPRLAADLYGLDI
LEENVEDSENNVTRFVVLSKNKQWAARPENDERIVTTFVFRVRNVPAALYKALGGFATNGVNMTKLESYQLGGRFIATQF
YADIEGHPEERSVQLALEELRFFTKEVRILGVYKGSDIRGTQLLAAE

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=279, Percent_Identity=34.4086021505376, Blast_Score=138, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 31806; Mature: 31806

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTNRISFQGEAGANSDTACRNMFPDMEPLPCPTFEDAFNAVETGAADLAMIPIENTLAG
CCCCEEEECCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCHHHH
RVADIHYLLPLADMHIVGEYFLPIHFQLMVLPGVRREEIKTVHSHIHALGQCRNVIRQNG
HHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
WKGVIAGDTAGAARLVADVKDRSMAALAPRLAADLYGLDILEENVEDSENNVTRFVVLSK
CCEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEC
NKQWAARPENDERIVTTFVFRVRNVPAALYKALGGFATNGVNMTKLESYQLGGRFIATQF
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCHHCCCCCEEEECCCCCCCEEEEEEE
YADIEGHPEERSVQLALEELRFFTKEVRILGVYKGSDIRGTQLLAAE
EECCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCEEEECC
>Mature Secondary Structure
MKTNRISFQGEAGANSDTACRNMFPDMEPLPCPTFEDAFNAVETGAADLAMIPIENTLAG
CCCCEEEECCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCHHHH
RVADIHYLLPLADMHIVGEYFLPIHFQLMVLPGVRREEIKTVHSHIHALGQCRNVIRQNG
HHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
WKGVIAGDTAGAARLVADVKDRSMAALAPRLAADLYGLDILEENVEDSENNVTRFVVLSK
CCEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEC
NKQWAARPENDERIVTTFVFRVRNVPAALYKALGGFATNGVNMTKLESYQLGGRFIATQF
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCHHCCCCCEEEECCCCCCCEEEEEEE
YADIEGHPEERSVQLALEELRFFTKEVRILGVYKGSDIRGTQLLAAE
EECCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]