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The map label for this gene is argD [H]

Identifier: 225630986

GI number: 225630986

Start: 1397940

End: 1399115

Strand: Reverse

Name: argD [H]

Synonym: WRi_013100

Alternate gene names: 225630986

Gene position: 1399115-1397940 (Counterclockwise)

Preceding gene: 225630990

Following gene: 225630985

Centisome position: 96.77

GC content: 36.22

Gene sequence:

>1176_bases
ATGACAATTTCTCCTATTTTGCCAGTTTATTCTCCTATTAACATAAATTTTTCTTATGGTAAAGATATTTACTTGTATGA
TATTGACGGTAAGCGCTACGTAGATTTTCACTCTGGAATAGCCGTTAGCAGCTTAGGTCACACCAATTCACGATTAATTA
GTGCTCTAAAATTGCAAGGAGAAAAATTATGGCATATATCAAATACCTATAATATACCTGCTGCCAATAATTTTGCAGAA
AAATTAATAAACAATAGTTTCGCTGACACTGTATTTTTCTCAAATTCTGGATCAGAGGCAGTAGAATGTGGACTTAAGAT
TGCTAGGATCTATCAAAATGGAAAAGGCAATAAAAATCGTCACAGAATTTTAACATTTCATGGTGCATTTCATGGAAGAA
CCTTTTTAACTTGTGCTACAAACGATAAACAGAAATTTTCTGAATTACTAAATCCCTACATTGATTGGTGTGATAACATC
GAGCCCAATATTGAGAGCGTAAAGAAAGCAATTTCAAGTGGTATAGGCGTTATATTAATAGAACCAATACAAGGGCAAGG
TGGTATCAAAGTAATGAATGAAGTCTTTATGAAAGAACTAAGAAGGCTGTGTGATGAAAATGACATATTGTTATTTTTTG
ATTGCGTACAATGCGGTGCTGGTAGGACAGGAAAATTATTCGCATACGAACATATAGGAGTGGAACCTGATATATGTGCT
CTTGCAAAGGGAATAGGCGGGGGGTTTCCGCTGGGGGCTTGTCTTGCAACTGAAAAGGCTGCTAAATATATGGCAGTTGG
TATGCACGGTTCCACTTTTGGTGGCAATCCGCTTGCAACCTCAGTAGGTAATGCTGTGCTCGAAGAATTGCTCAGCCCCG
GCTTTTTGAAAAATGTTGAAATTAGAGGTAAATACTTAAAAAATAAACTAGAAGACTTAGCAAGTAAATTTCCAATAATA
GAGGAAGTAAGAGGGAAAGGGTTAATGCTTGGAATAAAAGTGAAAGCAGACAATCAAAAGTTTGCAGAAGAGTTAAGTCA
TCGCGGCTTGCTTACTGTTGGGGTAACATCAGATAACGTTGTGAGAATTTTACCTCCACTCATTATCACTGAAAAAGAGA
TTGATGAAGGCATCGAGATTTTGACTCAATATTTATCTGAGAAATCTTCTGATTAG

Upstream 100 bases:

>100_bases
GTGCAGAAAACATTAATTTACCTATCTTATACATATCCTTACTCATTGCGAAACAACGGCTTTTATGTTATTAATAATAA
AATTTAGCATATAATATTTT

Downstream 100 bases:

>100_bases
ATACTTGCATTAATATGAACGACAATCTGGTATGCTTAGGAATTATTACCTCTCCTCACGGAATTAAAGGAGCTGTTAAA
GTAAAAACCTTTACTGAAAA

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTISPILPVYSPININFSYGKDIYLYDIDGKRYVDFHSGIAVSSLGHTNSRLISALKLQGEKLWHISNTYNIPAANNFAE
KLINNSFADTVFFSNSGSEAVECGLKIARIYQNGKGNKNRHRILTFHGAFHGRTFLTCATNDKQKFSELLNPYIDWCDNI
EPNIESVKKAISSGIGVILIEPIQGQGGIKVMNEVFMKELRRLCDENDILLFFDCVQCGAGRTGKLFAYEHIGVEPDICA
LAKGIGGGFPLGACLATEKAAKYMAVGMHGSTFGGNPLATSVGNAVLEELLSPGFLKNVEIRGKYLKNKLEDLASKFPII
EEVRGKGLMLGIKVKADNQKFAEELSHRGLLTVGVTSDNVVRILPPLIITEKEIDEGIEILTQYLSEKSSD

Sequences:

>Translated_391_residues
MTISPILPVYSPININFSYGKDIYLYDIDGKRYVDFHSGIAVSSLGHTNSRLISALKLQGEKLWHISNTYNIPAANNFAE
KLINNSFADTVFFSNSGSEAVECGLKIARIYQNGKGNKNRHRILTFHGAFHGRTFLTCATNDKQKFSELLNPYIDWCDNI
EPNIESVKKAISSGIGVILIEPIQGQGGIKVMNEVFMKELRRLCDENDILLFFDCVQCGAGRTGKLFAYEHIGVEPDICA
LAKGIGGGFPLGACLATEKAAKYMAVGMHGSTFGGNPLATSVGNAVLEELLSPGFLKNVEIRGKYLKNKLEDLASKFPII
EEVRGKGLMLGIKVKADNQKFAEELSHRGLLTVGVTSDNVVRILPPLIITEKEIDEGIEILTQYLSEKSSD
>Mature_390_residues
TISPILPVYSPININFSYGKDIYLYDIDGKRYVDFHSGIAVSSLGHTNSRLISALKLQGEKLWHISNTYNIPAANNFAEK
LINNSFADTVFFSNSGSEAVECGLKIARIYQNGKGNKNRHRILTFHGAFHGRTFLTCATNDKQKFSELLNPYIDWCDNIE
PNIESVKKAISSGIGVILIEPIQGQGGIKVMNEVFMKELRRLCDENDILLFFDCVQCGAGRTGKLFAYEHIGVEPDICAL
AKGIGGGFPLGACLATEKAAKYMAVGMHGSTFGGNPLATSVGNAVLEELLSPGFLKNVEIRGKYLKNKLEDLASKFPIIE
EVRGKGLMLGIKVKADNQKFAEELSHRGLLTVGVTSDNVVRILPPLIITEKEIDEGIEILTQYLSEKSSD

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=383, Percent_Identity=32.1148825065274, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI13994255, Length=446, Percent_Identity=30.4932735426009, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI284507298, Length=300, Percent_Identity=33, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI37574042, Length=408, Percent_Identity=26.9607843137255, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI226442705, Length=412, Percent_Identity=25.9708737864078, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI226442709, Length=335, Percent_Identity=27.7611940298507, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI188536080, Length=430, Percent_Identity=23.4883720930233, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38679950, Length=430, Percent_Identity=23.4883720930233, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38679946, Length=430, Percent_Identity=23.4883720930233, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI24119277, Length=400, Percent_Identity=26.25, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1788044, Length=378, Percent_Identity=39.6825396825397, Blast_Score=288, Evalue=4e-79,
Organism=Escherichia coli, GI1789759, Length=386, Percent_Identity=37.5647668393782, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI1789016, Length=404, Percent_Identity=34.4059405940594, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI145693181, Length=373, Percent_Identity=32.7077747989276, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=31.75, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI1786991, Length=304, Percent_Identity=32.5657894736842, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786349, Length=324, Percent_Identity=28.0864197530864, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=386, Percent_Identity=30.8290155440415, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI32564660, Length=446, Percent_Identity=30.4932735426009, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI25144274, Length=384, Percent_Identity=27.6041666666667, Blast_Score=147, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=421, Percent_Identity=26.3657957244656, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17541228, Length=429, Percent_Identity=21.6783216783217, Blast_Score=85, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=389, Percent_Identity=35.73264781491, Blast_Score=229, Evalue=6e-61,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=32.5870646766169, Blast_Score=185, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6324386, Length=460, Percent_Identity=27.1739130434783, Blast_Score=113, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6321456, Length=425, Percent_Identity=24.7058823529412, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=31.9480519480519, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI28574759, Length=419, Percent_Identity=31.2649164677804, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI161085790, Length=419, Percent_Identity=30.7875894988067, Blast_Score=175, Evalue=4e-44,
Organism=Drosophila melanogaster, GI21356575, Length=418, Percent_Identity=25.8373205741627, Blast_Score=118, Evalue=6e-27,
Organism=Drosophila melanogaster, GI281366494, Length=419, Percent_Identity=27.9236276849642, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667139, Length=419, Percent_Identity=27.9236276849642, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667143, Length=419, Percent_Identity=27.9236276849642, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42928; Mature: 42797

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTISPILPVYSPININFSYGKDIYLYDIDGKRYVDFHSGIAVSSLGHTNSRLISALKLQG
CCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECCCEEEECCCCCHHHHHHHHHHCC
EKLWHISNTYNIPAANNFAEKLINNSFADTVFFSNSGSEAVECGLKIARIYQNGKGNKNR
CEEEEECCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHEEHHHCCCCCCCC
HRILTFHGAFHGRTFLTCATNDKQKFSELLNPYIDWCDNIEPNIESVKKAISSGIGVILI
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEE
EPIQGQGGIKVMNEVFMKELRRLCDENDILLFFDCVQCGAGRTGKLFAYEHIGVEPDICA
EECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCCCEEEEECCCCCCCHHH
LAKGIGGGFPLGACLATEKAAKYMAVGMHGSTFGGNPLATSVGNAVLEELLSPGFLKNVE
HHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEECHH
IRGKYLKNKLEDLASKFPIIEEVRGKGLMLGIKVKADNQKFAEELSHRGLLTVGVTSDNV
HHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEEEECCCHHHHHHHHCCCEEEEECCCCCE
VRILPPLIITEKEIDEGIEILTQYLSEKSSD
EEECCCCEEEHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TISPILPVYSPININFSYGKDIYLYDIDGKRYVDFHSGIAVSSLGHTNSRLISALKLQG
CCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECCCEEEECCCCCHHHHHHHHHHCC
EKLWHISNTYNIPAANNFAEKLINNSFADTVFFSNSGSEAVECGLKIARIYQNGKGNKNR
CEEEEECCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHEEHHHCCCCCCCC
HRILTFHGAFHGRTFLTCATNDKQKFSELLNPYIDWCDNIEPNIESVKKAISSGIGVILI
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEE
EPIQGQGGIKVMNEVFMKELRRLCDENDILLFFDCVQCGAGRTGKLFAYEHIGVEPDICA
EECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHCCCCCCCEEEEECCCCCCCHHH
LAKGIGGGFPLGACLATEKAAKYMAVGMHGSTFGGNPLATSVGNAVLEELLSPGFLKNVE
HHHHCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEECHH
IRGKYLKNKLEDLASKFPIIEEVRGKGLMLGIKVKADNQKFAEELSHRGLLTVGVTSDNV
HHHHHHHHHHHHHHHHCCCHHHHCCCEEEEEEEEECCCHHHHHHHHCCCEEEEECCCCCE
VRILPPLIITEKEIDEGIEILTQYLSEKSSD
EEECCCCEEEHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]