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The map label for this gene is htpG [H]

Identifier: 225630981

GI number: 225630981

Start: 1389984

End: 1391891

Strand: Direct

Name: htpG [H]

Synonym: WRi_013040

Alternate gene names: 225630981

Gene position: 1389984-1391891 (Clockwise)

Preceding gene: 225630980

Following gene: 225630982

Centisome position: 96.13

GC content: 37.32

Gene sequence:

>1908_bases
ATGGAGCTCAAAATGCATAATGTACAAGAAACTGAAAATTTAAAATTTGACGCTGAGGTAGGGAAAGTACTGAATATAGT
GATTCATTCACTTTACACCAATAAAGACATTTTTCTGCGTGAATTAATATCAAATGCATCAGATGCATGTGATAAGTTGC
GCTATGAATCTCAACTAAACCCTAATTTGCTAGATTTGAGTGACGAATTAAAAATCACTATCAGCTCCAATAAAGATAAG
AACGAGCTATATATCACTGATAATGGCATTGGAATGAATAGACAGGATTTAATAGACAATCTTGGTACAATTGCAAGCTC
TGGTACGCAAAAGTTCTTGGATGCGATTAAGAATAGCAAGGATTCAAGCCAAACTGTGGAGCTGATTGGGAAGTTTGGTG
TTGGTTTTTACTCAAGCTTTATGGTTGCATCAGAAGTAATAGTAGAATCGAGAAAAGCTGGAGAAGAGGAGTCTTGGATC
TGGCAATCCAAAGGAGATGGGAAATATTCAATCAGCAAGTCAGATAATCAAGTCCCTCGCGGAACCAAAATTACGCTCAT
TATGCATCCTGAAGAAAACGAGTTTTTAGATAAATTTCGTGTTGAAAATATTGTCACTACTTACTCTGATCACATAAATT
TTCCTGTTGAATTTATAGACGAAGAAGGAAAAAGTGAAAAGTTAAACAGTAAGGCTGCAATTTGGACTAAGCCAAAAAAT
GACGTTACTCAAGAGGAGCACAACGATTTTTTCCGCAGTGTTGCCCACGTTGGCGGGGAGCCCTGGATGATATTGCATAA
TAAAAATGAAGGTGCAATAGAATATACAAATTTGCTTTATGTTCCTTCTATAAAACCTTTTGATTTATTCCATCCAGATA
GACGTTGCTCTGTGAAGTTATATGTAAATAAAGTATTTATCACTGAAGATAACGTACAGATTATACCACAATACTTGCGT
TTTCTGAAAGGCGTGGTTGATTCACCGGACTTGCCTCTTAATATCAGCAGAGAAACGCTGCAGAATAATCGTGTTGTTGA
GCAGATCAGAAAATCTCTCACTAAGCGTGTGATATCAGAGCTCGGTAAAAAGGCAAAAGAGAATTTAGAGGAGTACACAA
AATTCTGGACCAATTTTGGTGCAGTATTAAAAGAGGGTCTTTGTGAAGCTATGCCAACTGATGAGAGAGAAGCGCTGCTC
TCGATTTGCAGATTTCATAGCACCGGTGATGAGAAGTTGATCAGCATTGATGATTATATAAGCAGAATGAAGCCTGAGCA
GGAACATATCTATTATCTCACCGGAAATAGCCTCGATTCAGTGAAAAACAGTCCGCAACTTGAGGGATTCGTCAGTAAAG
GACTAGAAGTGCTCCTATTTGTTGATCCAGTTGATGACTTTTGGACTAGTGTAATTCATGAATACAAAGATCAGAAAATC
AAGTCTGTAACCCGTGCAGATGTTGATTTGGAAAAATTCTCTTCAGAAGAAGATAAGACAGATGAAGAAAATAAATCAAA
TGGAGAAAAAACTGAGGAAACTATACTGCAATATTTTACCACAGTGCTTGGAGATTCAGTAAAAAGCGTAAAAATTTCCA
AAAAATTGACTGATAGTCCCGTATGCCTAGCGGTTGATGAAGGTGCTATGGATCTTCGCATGGAGCGTTTTTTGCGTGAA
CAAAAGCAGCTAAATTACCGCACGCCAAAGGTGCTGGAAATTAACACTAAACATCCTGTAATAAAAAGTATAATGAAATC
TCACGCTGAAAATGGTGAAAACCCAACATTGGAAGACATGATTCATTTATTATTTTACCAAGCTTGTATAGTGGAAGGTG
AAGAGATGGATGACGCGAGCAGCTTTGCTAAGAGACTGAATAATTTGCTTGGCAAGATTTCTGTTTAA

Upstream 100 bases:

>100_bases
AAATTGGGTGTCATAATAACTACACCCACATTAATTTTGGTGTACGTGACCTTGAAAGATCGTGATTCAATACTTAAATT
ATTAGGGTAGTAGGCAAATA

Downstream 100 bases:

>100_bases
TGCTATACTTAGCTTAGCTATTAATTAGGGGTAAAACATGTTTGGTTCCAATTTTAGAGACTTTGTATCACAGGATGCAA
CTTCACAGGGCCAATCAAAT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MELKMHNVQETENLKFDAEVGKVLNIVIHSLYTNKDIFLRELISNASDACDKLRYESQLNPNLLDLSDELKITISSNKDK
NELYITDNGIGMNRQDLIDNLGTIASSGTQKFLDAIKNSKDSSQTVELIGKFGVGFYSSFMVASEVIVESRKAGEEESWI
WQSKGDGKYSISKSDNQVPRGTKITLIMHPEENEFLDKFRVENIVTTYSDHINFPVEFIDEEGKSEKLNSKAAIWTKPKN
DVTQEEHNDFFRSVAHVGGEPWMILHNKNEGAIEYTNLLYVPSIKPFDLFHPDRRCSVKLYVNKVFITEDNVQIIPQYLR
FLKGVVDSPDLPLNISRETLQNNRVVEQIRKSLTKRVISELGKKAKENLEEYTKFWTNFGAVLKEGLCEAMPTDEREALL
SICRFHSTGDEKLISIDDYISRMKPEQEHIYYLTGNSLDSVKNSPQLEGFVSKGLEVLLFVDPVDDFWTSVIHEYKDQKI
KSVTRADVDLEKFSSEEDKTDEENKSNGEKTEETILQYFTTVLGDSVKSVKISKKLTDSPVCLAVDEGAMDLRMERFLRE
QKQLNYRTPKVLEINTKHPVIKSIMKSHAENGENPTLEDMIHLLFYQACIVEGEEMDDASSFAKRLNNLLGKISV

Sequences:

>Translated_635_residues
MELKMHNVQETENLKFDAEVGKVLNIVIHSLYTNKDIFLRELISNASDACDKLRYESQLNPNLLDLSDELKITISSNKDK
NELYITDNGIGMNRQDLIDNLGTIASSGTQKFLDAIKNSKDSSQTVELIGKFGVGFYSSFMVASEVIVESRKAGEEESWI
WQSKGDGKYSISKSDNQVPRGTKITLIMHPEENEFLDKFRVENIVTTYSDHINFPVEFIDEEGKSEKLNSKAAIWTKPKN
DVTQEEHNDFFRSVAHVGGEPWMILHNKNEGAIEYTNLLYVPSIKPFDLFHPDRRCSVKLYVNKVFITEDNVQIIPQYLR
FLKGVVDSPDLPLNISRETLQNNRVVEQIRKSLTKRVISELGKKAKENLEEYTKFWTNFGAVLKEGLCEAMPTDEREALL
SICRFHSTGDEKLISIDDYISRMKPEQEHIYYLTGNSLDSVKNSPQLEGFVSKGLEVLLFVDPVDDFWTSVIHEYKDQKI
KSVTRADVDLEKFSSEEDKTDEENKSNGEKTEETILQYFTTVLGDSVKSVKISKKLTDSPVCLAVDEGAMDLRMERFLRE
QKQLNYRTPKVLEINTKHPVIKSIMKSHAENGENPTLEDMIHLLFYQACIVEGEEMDDASSFAKRLNNLLGKISV
>Mature_635_residues
MELKMHNVQETENLKFDAEVGKVLNIVIHSLYTNKDIFLRELISNASDACDKLRYESQLNPNLLDLSDELKITISSNKDK
NELYITDNGIGMNRQDLIDNLGTIASSGTQKFLDAIKNSKDSSQTVELIGKFGVGFYSSFMVASEVIVESRKAGEEESWI
WQSKGDGKYSISKSDNQVPRGTKITLIMHPEENEFLDKFRVENIVTTYSDHINFPVEFIDEEGKSEKLNSKAAIWTKPKN
DVTQEEHNDFFRSVAHVGGEPWMILHNKNEGAIEYTNLLYVPSIKPFDLFHPDRRCSVKLYVNKVFITEDNVQIIPQYLR
FLKGVVDSPDLPLNISRETLQNNRVVEQIRKSLTKRVISELGKKAKENLEEYTKFWTNFGAVLKEGLCEAMPTDEREALL
SICRFHSTGDEKLISIDDYISRMKPEQEHIYYLTGNSLDSVKNSPQLEGFVSKGLEVLLFVDPVDDFWTSVIHEYKDQKI
KSVTRADVDLEKFSSEEDKTDEENKSNGEKTEETILQYFTTVLGDSVKSVKISKKLTDSPVCLAVDEGAMDLRMERFLRE
QKQLNYRTPKVLEINTKHPVIKSIMKSHAENGENPTLEDMIHLLFYQACIVEGEEMDDASSFAKRLNNLLGKISV

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=632, Percent_Identity=34.4936708860759, Blast_Score=357, Evalue=1e-98,
Organism=Homo sapiens, GI154146191, Length=422, Percent_Identity=32.4644549763033, Blast_Score=228, Evalue=2e-59,
Organism=Homo sapiens, GI153792590, Length=422, Percent_Identity=32.4644549763033, Blast_Score=225, Evalue=1e-58,
Organism=Homo sapiens, GI4507677, Length=419, Percent_Identity=31.0262529832936, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI20149594, Length=414, Percent_Identity=32.3671497584541, Blast_Score=221, Evalue=2e-57,
Organism=Escherichia coli, GI1786679, Length=634, Percent_Identity=41.3249211356467, Blast_Score=499, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17559162, Length=673, Percent_Identity=34.6210995542348, Blast_Score=392, Evalue=1e-109,
Organism=Caenorhabditis elegans, GI17542208, Length=672, Percent_Identity=34.5238095238095, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI115535205, Length=655, Percent_Identity=32.2137404580153, Blast_Score=311, Evalue=6e-85,
Organism=Caenorhabditis elegans, GI115535167, Length=432, Percent_Identity=34.7222222222222, Blast_Score=256, Evalue=3e-68,
Organism=Saccharomyces cerevisiae, GI6325016, Length=415, Percent_Identity=35.421686746988, Blast_Score=263, Evalue=5e-71,
Organism=Saccharomyces cerevisiae, GI6323840, Length=415, Percent_Identity=35.421686746988, Blast_Score=263, Evalue=5e-71,
Organism=Drosophila melanogaster, GI21357739, Length=683, Percent_Identity=33.2357247437775, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24586016, Length=637, Percent_Identity=32.0251177394035, Blast_Score=312, Evalue=5e-85,
Organism=Drosophila melanogaster, GI17647529, Length=414, Percent_Identity=35.2657004830918, Blast_Score=257, Evalue=2e-68,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72557; Mature: 72557

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKMHNVQETENLKFDAEVGKVLNIVIHSLYTNKDIFLRELISNASDACDKLRYESQLN
CCCCCCCCCHHCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PNLLDLSDELKITISSNKDKNELYITDNGIGMNRQDLIDNLGTIASSGTQKFLDAIKNSK
CCEECCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCC
DSSQTVELIGKFGVGFYSSFMVASEVIVESRKAGEEESWIWQSKGDGKYSISKSDNQVPR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCCCCCC
GTKITLIMHPEENEFLDKFRVENIVTTYSDHINFPVEFIDEEGKSEKLNSKAAIWTKPKN
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCCHHCCCCCEEEECCCC
DVTQEEHNDFFRSVAHVGGEPWMILHNKNEGAIEYTNLLYVPSIKPFDLFHPDRRCSVKL
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEE
YVNKVFITEDNVQIIPQYLRFLKGVVDSPDLPLNISRETLQNNRVVEQIRKSLTKRVISE
EEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
LGKKAKENLEEYTKFWTNFGAVLKEGLCEAMPTDEREALLSICRFHSTGDEKLISIDDYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHH
SRMKPEQEHIYYLTGNSLDSVKNSPQLEGFVSKGLEVLLFVDPVDDFWTSVIHEYKDQKI
HHCCCCCCEEEEEECCCHHHHCCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHH
KSVTRADVDLEKFSSEEDKTDEENKSNGEKTEETILQYFTTVLGDSVKSVKISKKLTDSP
HHHHHHCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEHHHHCCCCC
VCLAVDEGAMDLRMERFLREQKQLNYRTPKVLEINTKHPVIKSIMKSHAENGENPTLEDM
EEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHH
IHLLFYQACIVEGEEMDDASSFAKRLNNLLGKISV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MELKMHNVQETENLKFDAEVGKVLNIVIHSLYTNKDIFLRELISNASDACDKLRYESQLN
CCCCCCCCCHHCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PNLLDLSDELKITISSNKDKNELYITDNGIGMNRQDLIDNLGTIASSGTQKFLDAIKNSK
CCEECCCCCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCC
DSSQTVELIGKFGVGFYSSFMVASEVIVESRKAGEEESWIWQSKGDGKYSISKSDNQVPR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEECCCCCCCCC
GTKITLIMHPEENEFLDKFRVENIVTTYSDHINFPVEFIDEEGKSEKLNSKAAIWTKPKN
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCCHHCCCCCEEEECCCC
DVTQEEHNDFFRSVAHVGGEPWMILHNKNEGAIEYTNLLYVPSIKPFDLFHPDRRCSVKL
CCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEE
YVNKVFITEDNVQIIPQYLRFLKGVVDSPDLPLNISRETLQNNRVVEQIRKSLTKRVISE
EEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHH
LGKKAKENLEEYTKFWTNFGAVLKEGLCEAMPTDEREALLSICRFHSTGDEKLISIDDYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHH
SRMKPEQEHIYYLTGNSLDSVKNSPQLEGFVSKGLEVLLFVDPVDDFWTSVIHEYKDQKI
HHCCCCCCEEEEEECCCHHHHCCCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHH
KSVTRADVDLEKFSSEEDKTDEENKSNGEKTEETILQYFTTVLGDSVKSVKISKKLTDSP
HHHHHHCCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEHHHHCCCCC
VCLAVDEGAMDLRMERFLREQKQLNYRTPKVLEINTKHPVIKSIMKSHAENGENPTLEDM
EEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCHHHH
IHLLFYQACIVEGEEMDDASSFAKRLNNLLGKISV
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA