Click here to switch to the map view.

The map label for this gene is ruvA [H]

Identifier: 225630965

GI number: 225630965

Start: 1375237

End: 1375809

Strand: Reverse

Name: ruvA [H]

Synonym: WRi_012870

Alternate gene names: 225630965

Gene position: 1375809-1375237 (Counterclockwise)

Preceding gene: 225630966

Following gene: 225630964

Centisome position: 95.15

GC content: 34.73

Gene sequence:

>573_bases
ATGATAGGAAATCTAAGCGGAATAGTTGATGAAGTGCGCAGTGATCACATAATCCTGAATGTGAATGATGTTGGCTATAT
GGTGTATCTTTCAGCCAAAACTTTAAGTGCTTGTGCAATTGGAAGTAGAATCAAATTACTTATCGAAACCTATGCAAATA
ACAGAGAAAACACTACTCAGCTATATGGTTTTATAAGCGAAGAAGAACAGCAGTGCTTGAGGTTGCTTGTCAAAGTAAGC
GGTGTTAGCTATAAAACTGCAATGTCAATTTTGAGTAAATTAACTCCAGAACAGCTATTTTTGGCAATTATGAATGAAGA
TAAAGTAACACTCAAGATGAGTGGACTTGGCCTGAAACTCATAAATCGAATCATCACTGAATTGAGTGGCAAAGTAAGTA
AACTAGAAATAAATAACAATAATTTTCATCCAATTAATGAAGATGCCCTTTCAGCATTGATCAATCTTGGATATGAAAAA
ATGAAAGCTTATGATACGATAAAAAAATACAGGCCAAATCTGGACACTAAGGATATTATTCGCATGGCGCTTAAGGAGCT
CTCAACATTATGA

Upstream 100 bases:

>100_bases
TTTGTCAAGTGGTTTTTTAGCCACGTTTCCCTGTTATAATGTTCGTTTGCTTGACCTAAGATCCGGGAGTATTTAAACTG
AACTCTATATAGTGTTAAAA

Downstream 100 bases:

>100_bases
AATCAATATCGTGCGGTAAAGAATATACTGAAGATGTGCGCAATATTAACATCAGGCCTGAGCAACTTGATGATTTTGTC
GGGCAAAAAGACTTAATACA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MIGNLSGIVDEVRSDHIILNVNDVGYMVYLSAKTLSACAIGSRIKLLIETYANNRENTTQLYGFISEEEQQCLRLLVKVS
GVSYKTAMSILSKLTPEQLFLAIMNEDKVTLKMSGLGLKLINRIITELSGKVSKLEINNNNFHPINEDALSALINLGYEK
MKAYDTIKKYRPNLDTKDIIRMALKELSTL

Sequences:

>Translated_190_residues
MIGNLSGIVDEVRSDHIILNVNDVGYMVYLSAKTLSACAIGSRIKLLIETYANNRENTTQLYGFISEEEQQCLRLLVKVS
GVSYKTAMSILSKLTPEQLFLAIMNEDKVTLKMSGLGLKLINRIITELSGKVSKLEINNNNFHPINEDALSALINLGYEK
MKAYDTIKKYRPNLDTKDIIRMALKELSTL
>Mature_190_residues
MIGNLSGIVDEVRSDHIILNVNDVGYMVYLSAKTLSACAIGSRIKLLIETYANNRENTTQLYGFISEEEQQCLRLLVKVS
GVSYKTAMSILSKLTPEQLFLAIMNEDKVTLKMSGLGLKLINRIITELSGKVSKLEINNNNFHPINEDALSALINLGYEK
MKAYDTIKKYRPNLDTKDIIRMALKELSTL

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=28.0788177339901, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 21319; Mature: 21319

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGNLSGIVDEVRSDHIILNVNDVGYMVYLSAKTLSACAIGSRIKLLIETYANNRENTTQ
CCCCHHHHHHHHCCCEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCHH
LYGFISEEEQQCLRLLVKVSGVSYKTAMSILSKLTPEQLFLAIMNEDKVTLKMSGLGLKL
HHEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCHHH
INRIITELSGKVSKLEINNNNFHPINEDALSALINLGYEKMKAYDTIKKYRPNLDTKDII
HHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHH
RMALKELSTL
HHHHHHHHCC
>Mature Secondary Structure
MIGNLSGIVDEVRSDHIILNVNDVGYMVYLSAKTLSACAIGSRIKLLIETYANNRENTTQ
CCCCHHHHHHHHCCCEEEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCHH
LYGFISEEEQQCLRLLVKVSGVSYKTAMSILSKLTPEQLFLAIMNEDKVTLKMSGLGLKL
HHEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCHHH
INRIITELSGKVSKLEINNNNFHPINEDALSALINLGYEKMKAYDTIKKYRPNLDTKDII
HHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHH
RMALKELSTL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA