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The map label for this gene is coq7 [H]

Identifier: 225630954

GI number: 225630954

Start: 1364787

End: 1365329

Strand: Direct

Name: coq7 [H]

Synonym: WRi_012760

Alternate gene names: 225630954

Gene position: 1364787-1365329 (Clockwise)

Preceding gene: 225630953

Following gene: 225630955

Centisome position: 94.39

GC content: 35.91

Gene sequence:

>543_bases
GTGGAGAAAGAAAGAAATCTAAATAATTTAAGGTACAGCAACAATCAGTTCTTGCAACAGGCAATTAGAGTAGATCACGC
TGGAGAATATGGAGCTATTTGCATTTATTCTGGTCAAAAATTTATTCTTAAGAAATCTTCTATAATCAATGAAATAATTG
AAATGGAAGAGCAGGAAAAAAAGCATTTTCACTATTTTAATGAGAAAATCAAAGAGCAAAAAGTTCGTCCTACTGTTTTG
TTGCCTGTTTGGCGTGTTTTAGGAGTGTCGCTTGGCGTTGCAACTGCCATTATGGGCAAAAAAGCTGCTATGGCTTGCAC
TGCTGCAGTTGAAGAAGTTATCGGGGAGCACTACAAAGAGCAAGTTTCACATTTAGAAGATGGGGAATTAAGAGAAACTA
TAAGTAAATTTCGCGACGAGGAGTTAGAGCACAAAGATATTGCAATTCAGCACAATGCTGAAAGCGCATTTGGCTACAAC
ATTTTATCATCATTCATAAAAACAGGCTGCAAAACTGCTATTTACTTGTCTAAGTTAATTTAA

Upstream 100 bases:

>100_bases
CCATCTTGTGACAGACCTCATTACGTTCTAGGTGTTTCCTTAGCAACATGGAATCTAATTTATCTCATAGTAGCTCTGTT
CGTATCAGGTAAGGTGTATT

Downstream 100 bases:

>100_bases
CTAAGCAGCTTTCTTAAAGTGTTTTAAATGTTCTGATAACAACAGAAACCAGGAAGGAATTCAAGTGTAACAATTATTTT
ATAACTATATTTACATATCA

Product: Coq7 family protein

Products: NA

Alternate protein names: 5-demethoxyubiquinone hydroxylase; DMQ hydroxylase [H]

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MEKERNLNNLRYSNNQFLQQAIRVDHAGEYGAICIYSGQKFILKKSSIINEIIEMEEQEKKHFHYFNEKIKEQKVRPTVL
LPVWRVLGVSLGVATAIMGKKAAMACTAAVEEVIGEHYKEQVSHLEDGELRETISKFRDEELEHKDIAIQHNAESAFGYN
ILSSFIKTGCKTAIYLSKLI

Sequences:

>Translated_180_residues
MEKERNLNNLRYSNNQFLQQAIRVDHAGEYGAICIYSGQKFILKKSSIINEIIEMEEQEKKHFHYFNEKIKEQKVRPTVL
LPVWRVLGVSLGVATAIMGKKAAMACTAAVEEVIGEHYKEQVSHLEDGELRETISKFRDEELEHKDIAIQHNAESAFGYN
ILSSFIKTGCKTAIYLSKLI
>Mature_180_residues
MEKERNLNNLRYSNNQFLQQAIRVDHAGEYGAICIYSGQKFILKKSSIINEIIEMEEQEKKHFHYFNEKIKEQKVRPTVL
LPVWRVLGVSLGVATAIMGKKAAMACTAAVEEVIGEHYKEQVSHLEDGELRETISKFRDEELEHKDIAIQHNAESAFGYN
ILSSFIKTGCKTAIYLSKLI

Specific function: Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol [H]

COG id: COG2941

COG function: function code H; Ubiquinone biosynthesis protein COQ7

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COQ7 family [H]

Homologues:

Organism=Homo sapiens, GI25453484, Length=163, Percent_Identity=53.9877300613497, Blast_Score=174, Evalue=4e-44,
Organism=Homo sapiens, GI300244542, Length=167, Percent_Identity=52.6946107784431, Blast_Score=174, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17552756, Length=174, Percent_Identity=41.3793103448276, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324699, Length=191, Percent_Identity=38.7434554973822, Blast_Score=132, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24640215, Length=176, Percent_Identity=50.5681818181818, Blast_Score=170, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012347
- InterPro:   IPR009078
- InterPro:   IPR011566 [H]

Pfam domain/function: PF03232 COQ7 [H]

EC number: NA

Molecular weight: Translated: 20604; Mature: 20604

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKERNLNNLRYSNNQFLQQAIRVDHAGEYGAICIYSGQKFILKKSSIINEIIEMEEQEK
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
KHFHYFNEKIKEQKVRPTVLLPVWRVLGVSLGVATAIMGKKAAMACTAAVEEVIGEHYKE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVSHLEDGELRETISKFRDEELEHKDIAIQHNAESAFGYNILSSFIKTGCKTAIYLSKLI
HHHCCCCCHHHHHHHHHHHHHCCHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKERNLNNLRYSNNQFLQQAIRVDHAGEYGAICIYSGQKFILKKSSIINEIIEMEEQEK
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
KHFHYFNEKIKEQKVRPTVLLPVWRVLGVSLGVATAIMGKKAAMACTAAVEEVIGEHYKE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVSHLEDGELRETISKFRDEELEHKDIAIQHNAESAFGYNILSSFIKTGCKTAIYLSKLI
HHHCCCCCHHHHHHHHHHHHHCCHHCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]