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The map label for this gene is mraY [H]

Identifier: 225630955

GI number: 225630955

Start: 1365910

End: 1366890

Strand: Direct

Name: mraY [H]

Synonym: WRi_012770

Alternate gene names: 225630955

Gene position: 1365910-1366890 (Clockwise)

Preceding gene: 225630954

Following gene: 225630956

Centisome position: 94.47

GC content: 31.8

Gene sequence:

>981_bases
ATGATCTTAGCTACAAAAGTATTTTTTACCTCATTTGTTTTTGGGTTTATTCTTTTTCCCTATTTTATAAAGCTTCTAAA
AAAAATAAGCAAAGATGGGCAACCAATTAGATCATGTGGACCAGAAAGTCATTTAATAACAAAAAAGAATGTACCACCTA
TGGGCGGAATAATAATACTGACTTCTTCTTTATTACCAATTTTACTCTGGGTTCAGTTAACACCAGAAATTTTGCTGCTG
ATATTGATAACTCTATTTTTTGCTCTACTTGGATTTATTGATGATTATTTAAAATTGAAGACAAATCACTATCGAGGTTT
AAGTGCAAAAACCAAAATACTTATTCAGTTTATTGTTGCTCTGGTTGGTGTGTTTATACTTAAGCTATACTCTGCTGAAT
GTTTTACAAAAACGTCCCTATTTAAAGGAGTAATAATAGATTTTGGCTATCTATATGTTCCGTTTGCTGCGTTTGTAATT
GTCGGCTCTTCTAATGCTGTGAATCTCACAGATGGTTTGGATGGCCTTGCTGCAACTCAAGTCATCACTTCCTTTGCTTT
TTTGGGGCTAATTGCATATATAACTCAAGCAGATATGAATATTACTTTATTCTGCATTGCATTTATAGGAGCTATTCTAA
GTTTCTTGTGGTTTAACACACATCCAGCAAAAATATTTATGGGTGATGTTGGTAGCTTGTCGGTAGGCGCAGCCTTAGGG
TTAACTAGTGTCCTAATTAAAAGAGAAATGCTTTTTGCCGTTATTGGAATAATTTTTGTAATAGAGACTCTATCTGTTAT
TATTCAGATATCATATTTTAAATATACAAAGTTTAAATATGGAGAAGGAAAAAGAGTTTTCCTTATGGCACCAATGCATC
ATCACTTTGAAAAGAAGGGATGGTCAGAAAATGTAATCGTTATGAAATTTTGGATAATTTCTATTATCTGTTCAGTTTTT
ACTATAACTTTCTTATTATAA

Upstream 100 bases:

>100_bases
AATCACAATGTTCGTACAGTTGTGGGTCAGGCTATAGGATGACAGAAGTTGACTTTATTAGCTATAGGTGGTATGACACT
CAGTCAATTTAAGTAAGCAG

Downstream 100 bases:

>100_bases
AAACCTATGAAATACCCAGACTTTACATTAGAAAATAAATTATCAGGAGTGATAGCAGGAGTGGATGAAGTTGGAAGAGG
TCCGCTAGCTGGTCCAGTAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MILATKVFFTSFVFGFILFPYFIKLLKKISKDGQPIRSCGPESHLITKKNVPPMGGIIILTSSLLPILLWVQLTPEILLL
ILITLFFALLGFIDDYLKLKTNHYRGLSAKTKILIQFIVALVGVFILKLYSAECFTKTSLFKGVIIDFGYLYVPFAAFVI
VGSSNAVNLTDGLDGLAATQVITSFAFLGLIAYITQADMNITLFCIAFIGAILSFLWFNTHPAKIFMGDVGSLSVGAALG
LTSVLIKREMLFAVIGIIFVIETLSVIIQISYFKYTKFKYGEGKRVFLMAPMHHHFEKKGWSENVIVMKFWIISIICSVF
TITFLL

Sequences:

>Translated_326_residues
MILATKVFFTSFVFGFILFPYFIKLLKKISKDGQPIRSCGPESHLITKKNVPPMGGIIILTSSLLPILLWVQLTPEILLL
ILITLFFALLGFIDDYLKLKTNHYRGLSAKTKILIQFIVALVGVFILKLYSAECFTKTSLFKGVIIDFGYLYVPFAAFVI
VGSSNAVNLTDGLDGLAATQVITSFAFLGLIAYITQADMNITLFCIAFIGAILSFLWFNTHPAKIFMGDVGSLSVGAALG
LTSVLIKREMLFAVIGIIFVIETLSVIIQISYFKYTKFKYGEGKRVFLMAPMHHHFEKKGWSENVIVMKFWIISIICSVF
TITFLL
>Mature_326_residues
MILATKVFFTSFVFGFILFPYFIKLLKKISKDGQPIRSCGPESHLITKKNVPPMGGIIILTSSLLPILLWVQLTPEILLL
ILITLFFALLGFIDDYLKLKTNHYRGLSAKTKILIQFIVALVGVFILKLYSAECFTKTSLFKGVIIDFGYLYVPFAAFVI
VGSSNAVNLTDGLDGLAATQVITSFAFLGLIAYITQADMNITLFCIAFIGAILSFLWFNTHPAKIFMGDVGSLSVGAALG
LTSVLIKREMLFAVIGIIFVIETLSVIIQISYFKYTKFKYGEGKRVFLMAPMHHHFEKKGWSENVIVMKFWIISIICSVF
TITFLL

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=317, Percent_Identity=41.6403785488959, Blast_Score=229, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 36413; Mature: 36413

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILATKVFFTSFVFGFILFPYFIKLLKKISKDGQPIRSCGPESHLITKKNVPPMGGIIIL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEECCCCCCCCHHHHH
TSSLLPILLWVQLTPEILLLILITLFFALLGFIDDYLKLKTNHYRGLSAKTKILIQFIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LVGVFILKLYSAECFTKTSLFKGVIIDFGYLYVPFAAFVIVGSSNAVNLTDGLDGLAATQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEECCCCCCHHHHHH
VITSFAFLGLIAYITQADMNITLFCIAFIGAILSFLWFNTHPAKIFMGDVGSLSVGAALG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
LTSVLIKREMLFAVIGIIFVIETLSVIIQISYFKYTKFKYGEGKRVFLMAPMHHHFEKKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEECCHHHHHHHCC
WSENVIVMKFWIISIICSVFTITFLL
CCCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MILATKVFFTSFVFGFILFPYFIKLLKKISKDGQPIRSCGPESHLITKKNVPPMGGIIIL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCEEECCCCCCCCHHHHH
TSSLLPILLWVQLTPEILLLILITLFFALLGFIDDYLKLKTNHYRGLSAKTKILIQFIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LVGVFILKLYSAECFTKTSLFKGVIIDFGYLYVPFAAFVIVGSSNAVNLTDGLDGLAATQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEECCCCCCHHHHHH
VITSFAFLGLIAYITQADMNITLFCIAFIGAILSFLWFNTHPAKIFMGDVGSLSVGAALG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
LTSVLIKREMLFAVIGIIFVIETLSVIIQISYFKYTKFKYGEGKRVFLMAPMHHHFEKKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCEEEEECCHHHHHHHCC
WSENVIVMKFWIISIICSVFTITFLL
CCCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA