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The map label for this gene is purQ [H]

Identifier: 225630682

GI number: 225630682

Start: 1049067

End: 1049864

Strand: Reverse

Name: purQ [H]

Synonym: WRi_009750

Alternate gene names: 225630682

Gene position: 1049864-1049067 (Counterclockwise)

Preceding gene: 225630683

Following gene: 225630681

Centisome position: 72.61

GC content: 36.22

Gene sequence:

>798_bases
ATGAAAATCACAGTCCTATCTGGTTATGGCTTAAATTGCGAAAAAGAAACTGCATTTGCATTTATGGAATGCAGCAGAAA
ACTTGGTATTGGTAATATTGAAGTAAAAATCGTTCACATTAACGATATCATAGATAATCCAGGTGAACTGAAATTAAGCA
ATATACTTGCAATTCCAGGGGGTTTTTCCTATGGTGATGACACTGGTGCTGGTAATGCGTTTGCTTTACGTATTAAAAAC
AACTTGTTGGATGAGTTTCAAGAGTTTTTATCTCAGGACAAGCTGATTATAGGAATATGTAATGGTTGTCAGATATTAGT
AAAATTAATTCCAGAGTTCTCTAATCTAGCTTTAATCCATAATGATATAGGCAATTACCAATGCCGCTGGATTAGAGTGA
GAGTTAATCCGCAGAGTAATTCTGTTTGGCTACGGGGTCTGAGTGAACTATATCTCCCTATTGCTCATGGGGAAGGCAAA
TTTTTTATGGATCAAGATATTTTGAACCAATTGATTGAGAGCAATTCCACCGCATTACGTTACATTGATAAAAATGGCAA
CTATGCTAACCTACAATTTCCTTACAATCCGAATGGATCTACATACGACCTAGCAGCTTTATCAGATAAAAGTGGAAGAG
TGCTAGCTTTAATGCCCCATCCAGAAAGGGGAATATTTTTTACCCAGCAAGATAATTGGTCCCTTGAAAAAGAAAAGAGC
AAGCGTTTAGGTGTTGCTGTGCCAAAATATGGCGATGGAATGCTTATATTTGAAAATGCACTGAAGTATTTTTGTTAA

Upstream 100 bases:

>100_bases
TGCTATCGCAATTATAGCTTTATTATTGGTGTTATTTGCGTTAAATTTAGTAGCAAATTTTGTAAAAAGGAAATTCGAAT
TTTTTAATTTTTAGCAATTC

Downstream 100 bases:

>100_bases
AATTTATTGATAGGGATTTATGGTCGAAATTATCCCCTGATATTGCAAAAAACTTGCTTGACAAGCCTTGCCAGTCCCCT
TATCATGAAACTGAAGCTAT

Product: phosphoribosylformylglycinamidine synthase I, putative

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKITVLSGYGLNCEKETAFAFMECSRKLGIGNIEVKIVHINDIIDNPGELKLSNILAIPGGFSYGDDTGAGNAFALRIKN
NLLDEFQEFLSQDKLIIGICNGCQILVKLIPEFSNLALIHNDIGNYQCRWIRVRVNPQSNSVWLRGLSELYLPIAHGEGK
FFMDQDILNQLIESNSTALRYIDKNGNYANLQFPYNPNGSTYDLAALSDKSGRVLALMPHPERGIFFTQQDNWSLEKEKS
KRLGVAVPKYGDGMLIFENALKYFC

Sequences:

>Translated_265_residues
MKITVLSGYGLNCEKETAFAFMECSRKLGIGNIEVKIVHINDIIDNPGELKLSNILAIPGGFSYGDDTGAGNAFALRIKN
NLLDEFQEFLSQDKLIIGICNGCQILVKLIPEFSNLALIHNDIGNYQCRWIRVRVNPQSNSVWLRGLSELYLPIAHGEGK
FFMDQDILNQLIESNSTALRYIDKNGNYANLQFPYNPNGSTYDLAALSDKSGRVLALMPHPERGIFFTQQDNWSLEKEKS
KRLGVAVPKYGDGMLIFENALKYFC
>Mature_265_residues
MKITVLSGYGLNCEKETAFAFMECSRKLGIGNIEVKIVHINDIIDNPGELKLSNILAIPGGFSYGDDTGAGNAFALRIKN
NLLDEFQEFLSQDKLIIGICNGCQILVKLIPEFSNLALIHNDIGNYQCRWIRVRVNPQSNSVWLRGLSELYLPIAHGEGK
FFMDQDILNQLIESNSTALRYIDKNGNYANLQFPYNPNGSTYDLAALSDKSGRVLALMPHPERGIFFTQQDNWSLEKEKS
KRLGVAVPKYGDGMLIFENALKYFC

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=248, Percent_Identity=33.4677419354839, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI48994899, Length=272, Percent_Identity=36.0294117647059, Blast_Score=120, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17553022, Length=280, Percent_Identity=27.5, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321498, Length=286, Percent_Identity=31.8181818181818, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24582111, Length=238, Percent_Identity=35.7142857142857, Blast_Score=137, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24582109, Length=238, Percent_Identity=35.7142857142857, Blast_Score=137, Evalue=8e-33,
Organism=Drosophila melanogaster, GI17137292, Length=238, Percent_Identity=35.7142857142857, Blast_Score=137, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 29723; Mature: 29723

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITVLSGYGLNCEKETAFAFMECSRKLGIGNIEVKIVHINDIIDNPGELKLSNILAIPG
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEEEEEEEECC
GFSYGDDTGAGNAFALRIKNNLLDEFQEFLSQDKLIIGICNGCQILVKLIPEFSNLALIH
CCCCCCCCCCCCEEEEEEEHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCEEEEE
NDIGNYQCRWIRVRVNPQSNSVWLRGLSELYLPIAHGEGKFFMDQDILNQLIESNSTALR
ECCCCEEEEEEEEEECCCCCCEEEEEHHHEEEEEECCCCCEEECHHHHHHHHHCCCEEEE
YIDKNGNYANLQFPYNPNGSTYDLAALSDKSGRVLALMPHPERGIFFTQQDNWSLEKEKS
EEECCCCEEEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCHHHC
KRLGVAVPKYGDGMLIFENALKYFC
CCCCEECCCCCCCEEEEEHHHHHCC
>Mature Secondary Structure
MKITVLSGYGLNCEKETAFAFMECSRKLGIGNIEVKIVHINDIIDNPGELKLSNILAIPG
CEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCEEEEEEEEECC
GFSYGDDTGAGNAFALRIKNNLLDEFQEFLSQDKLIIGICNGCQILVKLIPEFSNLALIH
CCCCCCCCCCCCEEEEEEEHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCEEEEE
NDIGNYQCRWIRVRVNPQSNSVWLRGLSELYLPIAHGEGKFFMDQDILNQLIESNSTALR
ECCCCEEEEEEEEEECCCCCCEEEEEHHHEEEEEECCCCCEEECHHHHHHHHHCCCEEEE
YIDKNGNYANLQFPYNPNGSTYDLAALSDKSGRVLALMPHPERGIFFTQQDNWSLEKEKS
EEECCCCEEEEEEEECCCCCEEEEEEECCCCCCEEEEECCCCCCEEEEECCCCCCCHHHC
KRLGVAVPKYGDGMLIFENALKYFC
CCCCEECCCCCCCEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA