Click here to switch to the map view.

The map label for this gene is folB [H]

Identifier: 225630595

GI number: 225630595

Start: 933733

End: 934119

Strand: Reverse

Name: folB [H]

Synonym: WRi_008630

Alternate gene names: 225630595

Gene position: 934119-933733 (Counterclockwise)

Preceding gene: 225630596

Following gene: 225630594

Centisome position: 64.61

GC content: 36.95

Gene sequence:

>387_bases
ATGTCTGCATGTAATCTTCTTATATCTGACTTACGGCTTTGGGTTCATTTAGGCTATAGTGCAGAAGAGAAGTATCATTC
TCAATTAGTTAGTGTTAATATTGATTTTACCTTTAAATCCCCCCCTTTAGGACTTACAACTGACCGGCTTGAGGATACTA
TATGCTACTTGGAGGTAGTTCAGAGTATTCAATCTCTCGTTCAAAGCAAGCAATTCAACTTAATCGAGCATTTAACTCAT
GATATATACAGGACCATTAATAACCTTGTGATGCAAAAAAAGCTTATTATTTCTTCTATAGGCGTAACTATTCACAAAGT
TGCACCACCTGTCCCCAGTGTGCATGGAGGTGTTTTCTTTACTTATCGTAATGCGTTGCAAGAATGA

Upstream 100 bases:

>100_bases
AAAGGGAGCAAGGCTCTTGTGGGGTTTTCTTGATGGAATGATGAATGCTAGCGTGTGTTAGTAGTTGTAAGTAGCTTAAA
CTCAGTGATGTTGGAATGCA

Downstream 100 bases:

>100_bases
TTTACATTTCTATTGGCTCAAATATGGGGAATCGCTTTTCCCATTTACAAAAGGCTGCTCAGTTACTGCAGGAACGCTAT
TTTAAAAATTTAAAATCTTC

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MSACNLLISDLRLWVHLGYSAEEKYHSQLVSVNIDFTFKSPPLGLTTDRLEDTICYLEVVQSIQSLVQSKQFNLIEHLTH
DIYRTINNLVMQKKLIISSIGVTIHKVAPPVPSVHGGVFFTYRNALQE

Sequences:

>Translated_128_residues
MSACNLLISDLRLWVHLGYSAEEKYHSQLVSVNIDFTFKSPPLGLTTDRLEDTICYLEVVQSIQSLVQSKQFNLIEHLTH
DIYRTINNLVMQKKLIISSIGVTIHKVAPPVPSVHGGVFFTYRNALQE
>Mature_127_residues
SACNLLISDLRLWVHLGYSAEEKYHSQLVSVNIDFTFKSPPLGLTTDRLEDTICYLEVVQSIQSLVQSKQFNLIEHLTHD
IYRTINNLVMQKKLIISSIGVTIHKVAPPVPSVHGGVFFTYRNALQE

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 14527; Mature: 14396

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSACNLLISDLRLWVHLGYSAEEKYHSQLVSVNIDFTFKSPPLGLTTDRLEDTICYLEVV
CCHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
QSIQSLVQSKQFNLIEHLTHDIYRTINNLVMQKKLIISSIGVTIHKVAPPVPSVHGGVFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCHH
TYRNALQE
EEHHHHCC
>Mature Secondary Structure 
SACNLLISDLRLWVHLGYSAEEKYHSQLVSVNIDFTFKSPPLGLTTDRLEDTICYLEVV
CHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHH
QSIQSLVQSKQFNLIEHLTHDIYRTINNLVMQKKLIISSIGVTIHKVAPPVPSVHGGVFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCHH
TYRNALQE
EEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]