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The map label for this gene is fabD [H]

Identifier: 225630572

GI number: 225630572

Start: 906187

End: 907167

Strand: Reverse

Name: fabD [H]

Synonym: WRi_008340

Alternate gene names: 225630572

Gene position: 907167-906187 (Counterclockwise)

Preceding gene: 225630576

Following gene: 225630565

Centisome position: 62.74

GC content: 37.1

Gene sequence:

>981_bases
ATGATTTTCGCTTTCCCTGGTCAGGGCTCTCAGTTTGTAGGAATGGGAAGGAGCTTATATAGTGAGTTTTCCGTTGCAAG
ACAAGTATTTAATGAAGTAGATAGCATATTGGGTAGAAAGCTGTCTCATTTAATCTTCAACGGTCCTATTGAAGAATTAA
CCATTACAGAAAACGCTCAGCCAGCTATAATGGCAGTATCAATTGCAATGCTACGTGTTATGGAGCATATGTTTGGCAAA
TCTCTTTTCACTGATCACAATGTTAAATATGTTTGTGGGCATTCAGTTGGCGAATATACAGCGCTGTGTGCTGCAGGAGC
GTTAACGCTTGAGTCTGCAATCAAGCTGCTGAAAGTTCGCAGCGAAGCAATGCATGAAGCTTCACTGAAATGTAAAGGCG
GAATGGTTGCGTTGCTTGGAGCAGAGATAAATGAAGTGGAAGATATATTGAAATCAGTTCAAATTGACGGAATTTGTGAA
ATTGCAAACGATAACGGTGGCGGACAAGTGGTTATAAGTGGCACTAGAGAAGCTCTTGAAATGTTACCCGATTTATTCAA
AAACTCGAGTGTGAGGAAACTAATTAAATTACAGGTTAGTGGGCCTTTTCATTCATCTCTTATGAAACCTGCTGATGAAA
AAGTTTTGGAGTTTTTGAAGGGTATTAAAATAACCCGTCCTATAGTTCCTTTGATAACAAATGTTACAGCTAAAGAGGAG
AGTGATCCCAAAGTTATAAAAACTTTACTCGCCAAGCAAGTTGTAAGCAGAGTGAAATGGAGAGAAATGGTTTTGTATAT
GTCAAGCCGTGGCATTAACAAATTTGTTGAAATTGGCCCTAATAAAGTTTTATCTAATTTGGTCAAAAGAATTGACCAAT
CTATCAGTACAAAAAATATAGATAGTATTGGTGATATTGACAGCTTCTTTAATGAATCATTAGTACTAACAGCGAAAAAT
TTAAAAGTTGGATTAAGTTAA

Upstream 100 bases:

>100_bases
TATTCTAGTGAACTTAATTCACTAAGTCAATCATTATTCTAAAATATTGACAAAAAATAGATAAAATGTTATACTCAATA
GGGAATAAATAATAGTTATC

Downstream 100 bases:

>100_bases
AACACATCTATTTGATGTCATTCCGGTGCATAACGCTGCCTAGCTGGAATGACAGAGGGTAATGCAAGAAATCAATGAAC
TACCTGTCATTTCATCAGGT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MIFAFPGQGSQFVGMGRSLYSEFSVARQVFNEVDSILGRKLSHLIFNGPIEELTITENAQPAIMAVSIAMLRVMEHMFGK
SLFTDHNVKYVCGHSVGEYTALCAAGALTLESAIKLLKVRSEAMHEASLKCKGGMVALLGAEINEVEDILKSVQIDGICE
IANDNGGGQVVISGTREALEMLPDLFKNSSVRKLIKLQVSGPFHSSLMKPADEKVLEFLKGIKITRPIVPLITNVTAKEE
SDPKVIKTLLAKQVVSRVKWREMVLYMSSRGINKFVEIGPNKVLSNLVKRIDQSISTKNIDSIGDIDSFFNESLVLTAKN
LKVGLS

Sequences:

>Translated_326_residues
MIFAFPGQGSQFVGMGRSLYSEFSVARQVFNEVDSILGRKLSHLIFNGPIEELTITENAQPAIMAVSIAMLRVMEHMFGK
SLFTDHNVKYVCGHSVGEYTALCAAGALTLESAIKLLKVRSEAMHEASLKCKGGMVALLGAEINEVEDILKSVQIDGICE
IANDNGGGQVVISGTREALEMLPDLFKNSSVRKLIKLQVSGPFHSSLMKPADEKVLEFLKGIKITRPIVPLITNVTAKEE
SDPKVIKTLLAKQVVSRVKWREMVLYMSSRGINKFVEIGPNKVLSNLVKRIDQSISTKNIDSIGDIDSFFNESLVLTAKN
LKVGLS
>Mature_326_residues
MIFAFPGQGSQFVGMGRSLYSEFSVARQVFNEVDSILGRKLSHLIFNGPIEELTITENAQPAIMAVSIAMLRVMEHMFGK
SLFTDHNVKYVCGHSVGEYTALCAAGALTLESAIKLLKVRSEAMHEASLKCKGGMVALLGAEINEVEDILKSVQIDGICE
IANDNGGGQVVISGTREALEMLPDLFKNSSVRKLIKLQVSGPFHSSLMKPADEKVLEFLKGIKITRPIVPLITNVTAKEE
SDPKVIKTLLAKQVVSRVKWREMVLYMSSRGINKFVEIGPNKVLSNLVKRIDQSISTKNIDSIGDIDSFFNESLVLTAKN
LKVGLS

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=306, Percent_Identity=36.6013071895425, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=38.3177570093458, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1787334, Length=299, Percent_Identity=34.4481605351171, Blast_Score=189, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=30.7432432432432, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17550940, Length=304, Percent_Identity=26.6447368421053, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24665753, Length=315, Percent_Identity=32.3809523809524, Blast_Score=151, Evalue=4e-37,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 35685; Mature: 35685

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFAFPGQGSQFVGMGRSLYSEFSVARQVFNEVDSILGRKLSHLIFNGPIEELTITENAQ
CEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCC
PAIMAVSIAMLRVMEHMFGKSLFTDHNVKYVCGHSVGEYTALCAAGALTLESAIKLLKVR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
SEAMHEASLKCKGGMVALLGAEINEVEDILKSVQIDGICEIANDNGGGQVVISGTREALE
HHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCHHHHH
MLPDLFKNSSVRKLIKLQVSGPFHSSLMKPADEKVLEFLKGIKITRPIVPLITNVTAKEE
HHHHHHCCCHHHHHHHEEECCCHHHHHCCCCHHHHHHHHHCCCHHCCHHHHHHCCCCCCC
SDPKVIKTLLAKQVVSRVKWREMVLYMSSRGINKFVEIGPNKVLSNLVKRIDQSISTKNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCC
DSIGDIDSFFNESLVLTAKNLKVGLS
CCCCCHHHHHCCCEEEEEECEEECCC
>Mature Secondary Structure
MIFAFPGQGSQFVGMGRSLYSEFSVARQVFNEVDSILGRKLSHLIFNGPIEELTITENAQ
CEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCC
PAIMAVSIAMLRVMEHMFGKSLFTDHNVKYVCGHSVGEYTALCAAGALTLESAIKLLKVR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
SEAMHEASLKCKGGMVALLGAEINEVEDILKSVQIDGICEIANDNGGGQVVISGTREALE
HHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCHHHHH
MLPDLFKNSSVRKLIKLQVSGPFHSSLMKPADEKVLEFLKGIKITRPIVPLITNVTAKEE
HHHHHHCCCHHHHHHHEEECCCHHHHHCCCCHHHHHHHHHCCCHHCCHHHHHHCCCCCCC
SDPKVIKTLLAKQVVSRVKWREMVLYMSSRGINKFVEIGPNKVLSNLVKRIDQSISTKNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCC
DSIGDIDSFFNESLVLTAKNLKVGLS
CCCCCHHHHHCCCEEEEEECEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]