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The map label for this gene is clpX [H]

Identifier: 225630254

GI number: 225630254

Start: 509570

End: 510847

Strand: Reverse

Name: clpX [H]

Synonym: WRi_004680

Alternate gene names: 225630254

Gene position: 510847-509570 (Counterclockwise)

Preceding gene: 225630255

Following gene: 225630253

Centisome position: 35.33

GC content: 36.7

Gene sequence:

>1278_bases
ATGGATAACAATAATGATTTACACTACTGTTCTTTTTGCAACAAGGCGCAAGATGAAGTAGATAAATTGATTACTAACTC
TTCGGATGGTTTAAAGGTGTTTATTTGTAATGAGTGCATAGAATTATCCCATAAAGCAATAAGTCAAAAGAAAGATAGAT
CTTTTAATTCAGATCGTATATCTGATATGAAGCTATTACTAAAGAAACCTGAGGATATAAAAAACTTTCTCAGCAAGCAT
GTTGTAGGTCAAGAACACGCGCAACACGTTTTATCTGTAGCTATGTATAACCATTGTCAATCCATGGTACAATTTCATGC
TATAAGTGATATTGAAATCGAGAAGTCAAATATAATGCTTATTGGTCCCACTGGTTCTGGTAAGACTTTGCTAGCCAAAA
CACTTGCTAAAGTTTCAGATGTGCCATTTGCTATGGCTGATGCGACAACTTTAACTGAGGCAGGTTATGTGGGTGATGAT
GTAGAAAGCGTGTTGTCGCGTTTATTACAAGCTGCAAATTATGACGTTGTAAAAGCACAGCGTGGTATAGTGTTTATAGA
TGAAATAGACAAGATTACAAGAAAATCTGAAAGCACTTCAATAACCCGTGACGTTTCAGGTGAAGGGGTCCAGCAAGCTC
TGCTTAAGATTATGGAGGGTACAGTTGCTTATGTTCCGCCACAAGGAGGGCGAAAACACCCACAACAAGAGTTTATACAA
GTGGATACTAGTAACATACTGTTTATTTGTGGAGGAGCTTTTGAAGGCCTCGATAAAATTATTGAAGCGAGAAAAAAGGG
AACGTCAGTTGGCTTTGGAGCAGATATAAGTCAGTCTAAAGAGCAAAAGAAAAAGAATGCTTTACATGATGTTCAACCTG
AAGATTTAATCAAATTCGGTTTAATACCCGAATTTGTAGGGCGGGTTCCAATAACTGCTGTTTTAGATGAGCTGGATCAT
GAAGATTTAATACATGTGTTGACAGAGCCAAGGAATGCACTAATAAAACAGTACAAAGCATTGCTTGCGTTTAGCAAAGT
AAACCTTGAGTTTTCAGATGAAGCAATATCAGCTATTGCTAAAAAGGCTATAAGCTACAAAACAGGTGCAAGAATGTTAC
GTGCTATCTTGGAGTCACTTTTGCTTGACATTATGTATACATCTGGAAACGGAGGCTTTGAAGGTAGCACTATAGTAATC
ACTAAGAAAATGGTAGAATTAGGAAAAGCAACGGTTAATCATAATAACAATGGCAATGTTATAACGGTTAATGATTAA

Upstream 100 bases:

>100_bases
ATCCTGAAGAAGCAAGGAAAATTGGCTTAATTGACAGGGTGATAGCTGAGCGTACAGATATTGAAATTGAAAATATTAAA
GTTAAACAAAAGGTGGGTTA

Downstream 100 bases:

>100_bases
TTTGAGGCATATATTATGAACATTGAACGTGCTGTAAGCTCTAGTTTTACTGCATTGCCAGTATTACCTTTAAGAGATGT
AGTAATTTTTCCAAATATAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MDNNNDLHYCSFCNKAQDEVDKLITNSSDGLKVFICNECIELSHKAISQKKDRSFNSDRISDMKLLLKKPEDIKNFLSKH
VVGQEHAQHVLSVAMYNHCQSMVQFHAISDIEIEKSNIMLIGPTGSGKTLLAKTLAKVSDVPFAMADATTLTEAGYVGDD
VESVLSRLLQAANYDVVKAQRGIVFIDEIDKITRKSESTSITRDVSGEGVQQALLKIMEGTVAYVPPQGGRKHPQQEFIQ
VDTSNILFICGGAFEGLDKIIEARKKGTSVGFGADISQSKEQKKKNALHDVQPEDLIKFGLIPEFVGRVPITAVLDELDH
EDLIHVLTEPRNALIKQYKALLAFSKVNLEFSDEAISAIAKKAISYKTGARMLRAILESLLLDIMYTSGNGGFEGSTIVI
TKKMVELGKATVNHNNNGNVITVND

Sequences:

>Translated_425_residues
MDNNNDLHYCSFCNKAQDEVDKLITNSSDGLKVFICNECIELSHKAISQKKDRSFNSDRISDMKLLLKKPEDIKNFLSKH
VVGQEHAQHVLSVAMYNHCQSMVQFHAISDIEIEKSNIMLIGPTGSGKTLLAKTLAKVSDVPFAMADATTLTEAGYVGDD
VESVLSRLLQAANYDVVKAQRGIVFIDEIDKITRKSESTSITRDVSGEGVQQALLKIMEGTVAYVPPQGGRKHPQQEFIQ
VDTSNILFICGGAFEGLDKIIEARKKGTSVGFGADISQSKEQKKKNALHDVQPEDLIKFGLIPEFVGRVPITAVLDELDH
EDLIHVLTEPRNALIKQYKALLAFSKVNLEFSDEAISAIAKKAISYKTGARMLRAILESLLLDIMYTSGNGGFEGSTIVI
TKKMVELGKATVNHNNNGNVITVND
>Mature_425_residues
MDNNNDLHYCSFCNKAQDEVDKLITNSSDGLKVFICNECIELSHKAISQKKDRSFNSDRISDMKLLLKKPEDIKNFLSKH
VVGQEHAQHVLSVAMYNHCQSMVQFHAISDIEIEKSNIMLIGPTGSGKTLLAKTLAKVSDVPFAMADATTLTEAGYVGDD
VESVLSRLLQAANYDVVKAQRGIVFIDEIDKITRKSESTSITRDVSGEGVQQALLKIMEGTVAYVPPQGGRKHPQQEFIQ
VDTSNILFICGGAFEGLDKIIEARKKGTSVGFGADISQSKEQKKKNALHDVQPEDLIKFGLIPEFVGRVPITAVLDELDH
EDLIHVLTEPRNALIKQYKALLAFSKVNLEFSDEAISAIAKKAISYKTGARMLRAILESLLLDIMYTSGNGGFEGSTIVI
TKKMVELGKATVNHNNNGNVITVND

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=303, Percent_Identity=51.4851485148515, Blast_Score=298, Evalue=8e-81,
Organism=Escherichia coli, GI1786642, Length=388, Percent_Identity=59.5360824742268, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI1790366, Length=226, Percent_Identity=35.3982300884956, Blast_Score=102, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71982905, Length=290, Percent_Identity=47.9310344827586, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI71982908, Length=290, Percent_Identity=47.9310344827586, Blast_Score=259, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI71988663, Length=395, Percent_Identity=39.2405063291139, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI71988660, Length=255, Percent_Identity=40, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6319704, Length=403, Percent_Identity=38.7096774193548, Blast_Score=251, Evalue=1e-67,
Organism=Drosophila melanogaster, GI24648291, Length=326, Percent_Identity=46.6257668711656, Blast_Score=291, Evalue=8e-79,
Organism=Drosophila melanogaster, GI24648289, Length=326, Percent_Identity=46.6257668711656, Blast_Score=290, Evalue=9e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46740; Mature: 46740

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNNDLHYCSFCNKAQDEVDKLITNSSDGLKVFICNECIELSHKAISQKKDRSFNSDRI
CCCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCHH
SDMKLLLKKPEDIKNFLSKHVVGQEHAQHVLSVAMYNHCQSMVQFHAISDIEIEKSNIML
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEE
IGPTGSGKTLLAKTLAKVSDVPFAMADATTLTEAGYVGDDVESVLSRLLQAANYDVVKAQ
EECCCCCHHHHHHHHHHHHCCCEEHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCEECC
RGIVFIDEIDKITRKSESTSITRDVSGEGVQQALLKIMEGTVAYVPPQGGRKHPQQEFIQ
CCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHE
VDTSNILFICGGAFEGLDKIIEARKKGTSVGFGADISQSKEQKKKNALHDVQPEDLIKFG
ECCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHC
LIPEFVGRVPITAVLDELDHEDLIHVLTEPRNALIKQYKALLAFSKVNLEFSDEAISAIA
CCHHHHCCCCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEECHHHHHHHH
KKAISYKTGARMLRAILESLLLDIMYTSGNGGFEGSTIVITKKMVELGKATVNHNNNGNV
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCE
ITVND
EEECC
>Mature Secondary Structure
MDNNNDLHYCSFCNKAQDEVDKLITNSSDGLKVFICNECIELSHKAISQKKDRSFNSDRI
CCCCCCEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCHH
SDMKLLLKKPEDIKNFLSKHVVGQEHAQHVLSVAMYNHCQSMVQFHAISDIEIEKSNIML
HHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEE
IGPTGSGKTLLAKTLAKVSDVPFAMADATTLTEAGYVGDDVESVLSRLLQAANYDVVKAQ
EECCCCCHHHHHHHHHHHHCCCEEHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCEECC
RGIVFIDEIDKITRKSESTSITRDVSGEGVQQALLKIMEGTVAYVPPQGGRKHPQQEFIQ
CCEEEEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHE
VDTSNILFICGGAFEGLDKIIEARKKGTSVGFGADISQSKEQKKKNALHDVQPEDLIKFG
ECCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHC
LIPEFVGRVPITAVLDELDHEDLIHVLTEPRNALIKQYKALLAFSKVNLEFSDEAISAIA
CCHHHHCCCCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEECHHHHHHHH
KKAISYKTGARMLRAILESLLLDIMYTSGNGGFEGSTIVITKKMVELGKATVNHNNNGNV
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCE
ITVND
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA